All Stories

  1. A series of spontaneously blinking dyes for super-resolution microscopy

    Article • Nature Chemical Biology, April 2026, Springer Science + Business Media

    Dr. Brian P English

  2. Compartmentalized cytoplasmic tradewinds direct soluble proteins

    Article • Nature Communications, March 2026, Springer Science + Business Media

    Dr. Brian P English

  3. Compartmentalized Cytoplasmic Flows Direct Protein Transport to the Cell’s Leading Edge

    Article • May 2024, Cold Spring Harbor Laboratory Press

    Dr. Brian P English

  4. Coumarin as a general switching auxiliary to prepare photochromic and spontaneously blinking fluorophores

    Article • May 2024, Cold Spring Harbor Laboratory Press

    Dr. Brian P English

  5. A series of spontaneously blinking dyes for super-resolution microscopy

    Article • February 2024, Cold Spring Harbor Laboratory Press

    Dr. Brian P English

  6. Cap-dependent translation initiation monitored in living cells

    Article • Nature Communications, November 2022, Springer Science + Business Media

    Dr. Brian P English

  7. BRD2 compartmentalizes the accessible genome

    Article • Nature Genetics, April 2022, Springer Science + Business Media

    Dr. Brian P English

  8. Cap-dependent translation initiation monitored in living cells

    Article • May 2021, Cold Spring Harbor Laboratory Press

    Dr. Brian P English

  9. Live-cell single particle imaging reveals the role of RNA polymerase II in histone H2A.Z eviction

    Article • eLife, April 2020, eLife

    Dr. Brian P English

  10. 3D ATAC-PALM: super-resolution imaging of the accessible genome

    Article • Nature Chemical Biology, March 2020, Springer Science + Business Media

    Dr. Brian P English

  11. Live-cell single particle imaging reveals the role of RNA polymerase II in histone H2A.Z eviction

    Article • February 2020, Cold Spring Harbor Laboratory Press

    Dr. Brian P English

  12. Super-resolution Imaging Reveals 3D Structure and Organizing Mechanism of Accessible Chromatin

    Article • June 2019, Cold Spring Harbor Laboratory Press

    Dr. Brian P English

  13. Erratum: Corrigendum: The 4D nucleome project

    Article • Nature, November 2017, Springer Science + Business Media

    Dr. Brian P English

  14. The 4D nucleome project

    Article • Nature, September 2017, Springer Science + Business Media

    Dr. Brian P English

  15. Synthesis of Janelia Fluor HaloTag and SNAP-Tag Ligands and Their Use in Cellular Imaging Experiments

    Article • January 2017, Springer Science + Business Media

    Dr. Brian P English

  16. Bright photoactivatable fluorophores for single-molecule imaging

    Article • Nature Chemical Biology, October 2016, Nature

    Dr. Brian P English

  17. Glutamate-induced RNA localization and translation in neurons

    Article • Proceedings of the National Academy of Sciences, October 2016, Proceedings of the National Academy of Sciences

    Dr. Brian P English

  18. Rapid dynamics of general transcription factor TFIIB binding during preinitiation complex assembly revealed by single-molecule analysis

    Article • Genes & Development, September 2016, Cold Spring Harbor Laboratory Press

    Dr. Brian P English

  19. Bright photoactivatable fluorophores for single-molecule imaging

    Article • July 2016, Cold Spring Harbor Laboratory Press

    Timothee Lionnet, Dr PENG DONG, Dr. Brian P English

  20. Protein-retention expansion microscopy of cells and tissues labeled using standard fluorescent proteins and antibodies

    Article • Nature Biotechnology, July 2016, Nature

    Dr. Brian P English

  21. Real-time quantification of single RNA translation dynamics in living cells

    Article • Science, May 2016, American Association for the Advancement of Science

    Dr. Brian P English

  22. RNA Polymerase II cluster dynamics predict mRNA output in living cells

    Article • eLife, May 2016, eLife

    Timothee Lionnet, Dr. Brian P English, Namrata Jayanth

  23. Simultaneous High-Speed Tracking of Multiple Single-Molecules Reveals Functional Interactions in Living Cells

    Article • Biophysical Journal, February 2016, Elsevier

    Dr. Brian P English

  24. Mapping translation 'hot-spots' in live cells by tracking single molecules of mRNA and ribosomes

    Article • eLife, January 2016, eLife

    Timothee Lionnet, Dr. Brian P English

  25. Tracking multiple single molecules in living cells

    Article • SPIE Newsroom, November 2015, SPIE

    Dr. Brian P English

  26. A three-camera imaging microscope for high-speed single-molecule tracking and super-resolution imaging in living cells

    Article • August 2015, SPIE

    Dr. Brian P English

  27. Inferring transient particle transport dynamics in live cells

    Article • Nature Chemical Biology, July 2015, Nature

    Dr. Brian P English

  28. High-performance probes for light and electron microscopy

    Article • Nature Chemical Biology, April 2015, Nature

    Dr. Brian P English

  29. A general method to improve fluorophores for live-cell and single-molecule microscopy

    Article • Nature Chemical Biology, January 2015, Nature

    Timothee Lionnet, Dr. Brian P English

  30. Bayesian Classification of Mrna and Kinetochore Transport Dynamics

    Article • Biophysical Journal, January 2015, Elsevier

    Dr. Brian P English

  31. Tracking Surface Glycans on Live Cancer Cells with Single-Molecule Sensitivity

    Article • Angewandte Chemie, December 2014, Wiley

    Dr. Brian P English

  32. Lattice light-sheet microscopy: Imaging molecules to embryos at high spatiotemporal resolution

    Article • Science, October 2014, American Association for the Advancement of Science

    Dr. Brian P English

  33. Photoswitchable Red Fluorescent Protein with a Large Stokes Shift

    Article • Chemistry & Biology, October 2014, Elsevier

    Dr. Brian P English

  34. Positive allosteric feedback regulation of the stringent response enzyme RelA by its product

    Article • EMBO Reports, July 2012, EMBO

    Dr. Brian P English

  35. Single molecule tracking fluorescence microscopy in mitochondria reveals highly dynamic but confined movement of Tom40

    Article • Scientific Reports, December 2011, Nature

    Dr. Brian P English

  36. Single-molecule investigations of the stringent response machinery in living bacterial cells

    Article • Proceedings of the National Academy of Sciences, July 2011, Proceedings of the National Academy of Sciences

    Dr. Brian P English

  37. Single Molecule Tracking Inside Individual Living Bacterial Cells

    Article • Biophysical Journal, January 2010, Elsevier

    Dr. Brian P English

  38. When Does the Michaelis−Menten Equation Hold for Fluctuating Enzymes?

    Article • The Journal of Physical Chemistry B, October 2006, American Chemical Society (ACS)

    Dr. Brian P English

  39. Ever-fluctuating single enzyme molecules: Michaelis-Menten equation revisited

    Article • Nature Chemical Biology, March 2006, Nature

    Dr. Brian P English

  40. Ever-fluctuating single enzyme molecules: Michaelis-Menten equation revisited

    Article • Nature Chemical Biology, December 2005, Nature

    Dr. Brian P English

  41. Fluctuating Enzymes:  Lessons from Single-Molecule Studies

    Article • Accounts of Chemical Research, December 2005, American Chemical Society (ACS)

    Dr. Brian P English

  42. Single-Molecule Michaelis−Menten Equations

    Article • The Journal of Physical Chemistry B, October 2005, American Chemical Society (ACS)

    Dr. Brian P English

  43. Development of a Novel Method To Populate Native Disulfide-Bonded Intermediates for Structural Characterization of Proteins:  Implications for the Mechanism of Oxidative Folding of RNase A †

    Article • Journal of the American Chemical Society, May 2002, American Chemical Society (ACS)

    Dr. Brian P English

  44. Abstract

    Article • eLife

    Dr. Brian P English