Dr. Braden C Fleming
Brown University
Professor, Medicine And Medical Sciences
United States
My co-authors include
Patrick Vavken
Find me at
My Publications
Peripheral shift in the viable chondrocyte population of the medial femoral condyle aft...
PLoS ONE
August 2021
Predictors of Healing Ligament Size and Magnetic Resonance Signal Intensity at 6 Months...
The American Journal of Sports Medicine
April 2019
Anatomic Features of the Tibial Plateau Predict Outcomes of ACL Reconstruction Within 7...
The American Journal of Sports Medicine
January 2019
Tibial tunnel widening following anterior cruciate ligament reconstruction: A retrospec...
The Knee
December 2018
Transcriptional Profiling of Synovium in a Porcine Model of Early Post-traumatic Osteoa...
Journal of Orthopaedic Research®
February 2018
Preoperative KOOS and SF-36 Scores Are Associated With the Development of Symptomatic K...
The American Journal of Sports Medicine
February 2018
Differences in the Lateral Compartment Joint Space Width After Anterior Cruciate Ligame...
The American Journal of Sports Medicine
February 2018
Magnetic resonance measurements of tissue quantity and quality using T2 * relaxometry p...
Journal of Orthopaedic Research®
December 2017
Synovial inflammation plays a greater role in post-traumatic osteoarthritis compared to...
BMC Musculoskeletal Disorders
December 2017
Limited Evidence Suggests a Protective Association Between Oral Contraceptive Pill Use ...
Sports Health A Multidisciplinary Approach
October 2017
Comparison of 2 Radiographic Techniques for Measurement of Tibiofemoral Joint Space Width
Orthopaedic Journal of Sports Medicine
September 2017
Transcriptional profiling of articular cartilage in a porcine model of early post-traum...
Journal of Orthopaedic Research®
August 2017
Structural and Anatomic Restoration of the Anterior Cruciate Ligament Is Associated Wit...
Orthopaedic Journal of Sports Medicine
August 2017
Bench-to-bedside: Bridge-enhanced anterior cruciate ligament repair
Journal of Orthopaedic Research®
July 2017
Conflicted
The American Journal of Sports Medicine
June 2017
Sensitivity of ACL volume and T 2 ∗ relaxation time to magnetic resonance imaging scan...
Journal of Biomechanics
May 2017
Reduction of friction by recombinant human proteoglycan 4 in IL-1α stimulated bovine ca...
Journal of Orthopaedic Research®
March 2017
Emerging Techniques for Tendon and Ligament MRI
February 2017
Intra-articular Recombinant Human Proteoglycan 4 Mitigates Cartilage Damage After Desta...
The American Journal of Sports Medicine
January 2017
ACL Graft Tensioning
January 2017
The Bridge-Enhanced Anterior Cruciate Ligament Repair (BEAR) Procedure: An Early Feasib...
Orthopaedic Journal of Sports Medicine
November 2016
Comparison of micro-CT post-processing methods for evaluating the trabecular bone volum...
Journal of Biomechanics
October 2016
Return to Play Following Anterior Cruciate Ligament Reconstruction
Clinics in Sports Medicine
October 2016
Arthroscopic irrigation of the bovine stifle joint increases cartilage surface friction...
Journal of Biomechanics
September 2016
Predictors of Lateral Compartment Joint Space Difference at a Minimum of Two Years afte...
Orthopaedic Journal of Sports Medicine
July 2016
Effect of Matching or Overconstraining Knee Laxity During Anterior Cruciate Ligament Re...
The American Journal of Sports Medicine
April 2016
Psychological Factors Associated With Anterior Cruciate Ligament Reconstruction Recovery
Orthopaedic Journal of Sports Medicine
March 2016
Abnormal Mechanical Loading Induces Cartilage Degeneration by Accelerating Meniscus Hyp...
The American Journal of Sports Medicine
January 2016
Extracellular matrix-blood composite injection reduces post-traumatic osteoarthritis af...
Journal of Orthopaedic Research®
December 2015
Lubricin deficiency in the murine lumbar intervertebral disc results in elevated torsio...
Journal of Biomechanics
July 2015
Sex Influences the Biomechanical Outcomes of Anterior Cruciate Ligament Reconstruction ...
The American Journal of Sports Medicine
July 2015
Effect of low-temperature ethylene oxide and electron beam sterilization on the in vitr...
Journal of Biomaterials Applications
June 2015
Attenuation of cartilage pathogenesis in post-traumatic osteoarthritis (PTOA) in mice b...
Journal of Orthopaedic Research®
April 2015
Electron beam sterilization does not have a detrimental effect on the ability of extrac...
Journal of Orthopaedic Research®
April 2015
T2* relaxometry and volume predict semi-quantitative histological scoring of an ACL bri...
Journal of Orthopaedic Research®
April 2015
Meniscus treatment and age associated with narrower radiographic joint space width 2–3 ...
Osteoarthritis and Cartilage
April 2015
The uncertainty of predicting intact anterior cruciate ligament degeneration in terms o...
Journal of Biomechanics
April 2015
Biomechanical Outcomes of Bridge-enhanced Anterior Cruciate Ligament Repair Are Influen...
Clinical Orthopaedics and Related Research
March 2015
Addition of Autologous Mesenchymal Stem Cells to Whole Blood for Bioenhanced ACL Repair...
The American Journal of Sports Medicine
December 2014
MRI Volume and Signal Intensity of ACL Graft Predict Clinical, Functional, and Patient-...
The American Journal of Sports Medicine
December 2014
Validation of Porcine Knee as a Sex-specific Model to Study Human Anterior Cruciate Lig...
Clinical Orthopaedics and Related Research
October 2014
Improving the clinical efficiency of T2⁎ mapping of ligament integrity
Journal of Biomechanics
July 2014
Time Zero
The American Journal of Sports Medicine
June 2014
Identification of α2-Macroglobulin as a Master Inhibitor of Cartilage-Degrading Factors...
Arthritis & Rheumatology
June 2014
In-Vitro Anatomic Double-Bundle and Single-Bundle Anterior Cruciate Ligament Reconstruc...
Arthroscopy The Journal of Arthroscopic and Related Surgery
June 2014
Indian Hedgehog in Synovial Fluid Is a Novel Marker for Early Cartilage Lesions in Huma...
International Journal of Molecular Sciences
April 2014
Increased platelet concentration does not improve functional graft healing in bio-enhan...
Knee Surgery Sports Traumatology Arthroscopy
March 2014
Disrupting the Indian hedgehog signaling pathway in vivo attenuates surgically induced ...
Arthritis Research & Therapy
January 2014
T 2 * MR relaxometry and ligament volume are associated with th...
Journal of Orthopaedic Research®
December 2013
Loss of extracellular matrix from articular cartilage is mediated by the synovium and l...
Osteoarthritis and Cartilage
December 2013
Histological Predictors of Maximum Failure Loads Differ Between the Healing ACL and ACL...
Orthopaedic Journal of Sports Medicine
November 2013
Tribosupplementation with Lubricin in Prevention of Post-Traumatic Arthritis
October 2013
Effects of ACL reconstruction surgery on muscle activity of the lower limb during a jum...
Journal of Orthopaedic Research®
August 2013
Automatic determination of an anatomical coordinate system for a three-dimensional mode...
Journal of Biomechanics
August 2013
Use of a Bioactive Scaffold to Stimulate Anterior Cruciate Ligament Healing Also Minimi...
The American Journal of Sports Medicine
July 2013
Biology of anterior cruciate ligament injury and repair: Kappa delta ann doner vaughn a...
Journal of Orthopaedic Research®
July 2013
Knee Biomechanics during a Jump-Cut Maneuver
Medicine & Science in Sports & Exercise
May 2013
Role of lubricin and boundary lubrication in the prevention of chondrocyte apoptosis
Proceedings of the National Academy of Sciences
March 2013
Kinematic differences between optical motion capture and biplanar videoradiography duri...
Journal of Biomechanics
February 2013
Pendulum mass affects the measurement of articular friction coefficient
Journal of Biomechanics
February 2013
In Situ, Noninvasive, T2*-Weighted MRI-Derived Parameters Predict Ex Vivo Structural Pr...
The American Journal of Sports Medicine
January 2013
Animal Models of Osteoarthritis: Challenges of Model Selection and Analysis
The AAPS Journal
January 2013
The ACL Handbook
January 2013
In Vitro Models of ACL Injury
January 2013
Outcome Assessment for ACL Tissue Engineering
January 2013
Bio-enhancement of ACL Graft Healing
January 2013
The Biology of the Normal ACL
January 2013
Effects of Suture Choice on Biomechanics and Physeal Status After Bioenhanced Anterior ...
Arthroscopy The Journal of Arthroscopic and Related Surgery
January 2013
The Effect of Initial Graft Tension After Anterior Cruciate Ligament Reconstruction
The American Journal of Sports Medicine
November 2012
A comparative anatomical study of the human knee and six animal species
The Knee
August 2012
Effects of single-bundle and double-bundle ACL reconstruction on tibiofemoral compressi...
The Knee
August 2012
The impact of forced joint exercise on lubricin biosynthesis from articular cartilage f...
Osteoarthritis and Cartilage
August 2012
Activation of Indian hedgehog promotes chondrocyte hypertrophy and upregulation of MMP-...
Osteoarthritis and Cartilage
July 2012
Preventing Friction-induced Chondrocyte Apoptosis: Comparison of Human Synovial Fluid a...
The Journal of Rheumatology
June 2012
Biomechanical Outcomes After Bioenhanced Anterior Cruciate Ligament Repair and Anterior...
Arthroscopy The Journal of Arthroscopic and Related Surgery
May 2012
Prevention of cartilage degeneration and gait asymmetry by lubricin tribosupplementatio...
Arthritis & Rheumatism
March 2012
Cyclic loading increases friction and changes cartilage surface integrity in lubricin-m...
Arthritis & Rheumatism
January 2012
Effect of muscle loads and torque applied to the tibia on the strain behavior of the an...
Clinical Biomechanics
December 2011
The use of magnetic resonance imaging to predict ACL graft structural properties
Journal of Biomechanics
November 2011
Paper # 255: Skeletal Maturity Significantly Affects Functional ACL Healing Using PRP
Arthroscopy The Journal of Arthroscopic and Related Surgery
October 2011
Accelerated Versus Nonaccelerated Rehabilitation After Anterior Cruciate Ligament Recon...
The American Journal of Sports Medicine
September 2011
Contact area and pressure in suture bridge rotator cuff repair using knotless lateral a...
Knee Surgery Sports Traumatology Arthroscopy
April 2011
VEGF receptor mRNA expression by ACL fibroblasts is associated with functional healing ...
Knee Surgery Sports Traumatology Arthroscopy
February 2011
Reduced platelet concentration does not harm PRP effectiveness for ACL repair in a porc...
Journal of Orthopaedic Research®
February 2011
The use of a non-benzodiazepine hypnotic sleep-aid (Zolpidem) in patients undergoing AC...
Knee Surgery Sports Traumatology Arthroscopy
January 2011
Static and Dynamic Error of a Biplanar Videoradiography System Using Marker-Based and M...
Journal of Biomechanical Engineering
January 2011
Activation of Indian hedgehog promotes chondrocyte hypertrophy and upregulation of MMP-...
Bone
October 2010
Effects of Supplemental Intra-articular Lubricin and Hyaluronic Acid on the Progression...
The American Journal of Sports Medicine
September 2010
Delay of 2 or 6 Weeks Adversely Affects the Functional Outcome of Augmented Primary Rep...
The American Journal of Sports Medicine
September 2010
The Effect of Skeletal Maturity on Functional Healing of the Anterior Cruciate Ligament
Journal of Bone and Joint Surgery
September 2010
Bone-to-Bone Fixation Enhances Functional Healing of the Porcine Anterior Cruciate Liga...
Arthroscopy The Journal of Arthroscopic and Related Surgery
September 2010
Effects of increased chronic loading on articular cartilage material properties in the ...
Journal of Biomechanics
August 2010
Prevention of cartilage degeneration and restoration of chondroprotection by lubricin t...
Arthritis & Rheumatism
May 2010
Quantitative Magnetic Resonance Imaging Detects Changes in Meniscal Volume In Vivo Afte...
The American Journal of Sports Medicine
May 2010
Automatic determination of anatomical coordinate systems for three-dimensional bone mod...
Journal of Biomechanics
May 2010
Delayed Gadolinium-Enhanced MR Imaging of Cartilage (dGEMRIC) following ACL injury
Osteoarthritis and Cartilage
May 2010
Reliable fusion of knee bone laser scans to establish ground truth for cartilage thickn...
March 2010
Collagen scaffold supplementation does not improve the functional properties of the rep...
Journal of Orthopaedic Research®
January 2010
Comparison of differential biomarkers of osteoarthritis with and without posttraumatic ...
Journal of Orthopaedic Research®
January 2010
Collagen-Platelet Composite Enhances Biomechanical and Histologic Healing of the Porcin...
The American Journal of Sports Medicine
November 2009
The impact of anterior cruciate ligament injury on lubricin metabolism and the effect o...
Arthritis & Rheumatism
October 2009
Comparison of two methods for calculating the frictional properties of articular cartil...
Journal of Biomechanics
August 2009
Collagen-Platelet Composites Improve the Biomechanical Properties of Healing Anterior C...
The American Journal of Sports Medicine
August 2009
Effects of Single-Bundle and Double-Bundle ACL Reconstruction on Tibiofemoral Forces an...
Arthroscopy The Journal of Arthroscopic and Related Surgery
June 2009
Platelet-rich plasma alone is not sufficient to enhance suture repair of the ACL in ske...
Journal of Orthopaedic Research®
May 2009
The use of platelets to affect functional healing of an anterior cruciate ligament (ACL...
Journal of Orthopaedic Research®
May 2009
Digital Radiographic Assessment of Tibiofemoral Joint Space Width – A Variance Compone...
The Journal of Knee Surgery
January 2009
Evaluation Criteria for Musculoskeletal and Craniofacial Tissue Engineering Constructs:...
Tissue Engineering Part A
December 2008
Quantitative MR imaging using “LiveWire” to measure tibiofemoral articular cartilage th...
Osteoarthritis and Cartilage
October 2008
Biomechanical comparison of single-row arthroscopic rotator cuff repair technique versu...
Journal of Shoulder and Elbow Surgery
September 2008
Tibiofemoral Compression Force Differences Using Laxity- and Force-Based Initial Graft ...
Arthroscopy The Journal of Arthroscopic and Related Surgery
September 2008
Can suture repair of ACL transection restore normal anteroposterior laxity of the knee?...
Journal of Orthopaedic Research®
June 2008
Effects of ACL interference screws on articular cartilage volume and thickness measurem...
Osteoarthritis and Cartilage
May 2008
A Systematic Review of Anterior Cruciate Ligament Reconstruction Rehabilitation – Part...
The Journal of Knee Surgery
January 2008
A Systematic Review of Anterior Cruciate Ligament Reconstruction Rehabilitation – Part...
The Journal of Knee Surgery
January 2008
Coefficients of friction, lubricin, and cartilage damage in the anterior cruciate ligam...
Journal of Orthopaedic Research®
January 2008
Measuring fixed charge density of goat articular cartilage using indentation methods an...
Journal of Biomechanics
January 2008
Decreased lubricin concentrations and markers of joint inflammation in the synovial flu...
Arthritis & Rheumatism
January 2008
Initial Fixation Strength of Massive Rotator Cuff Tears: In Vitro Comparison of Single-...
Arthroscopy The Journal of Arthroscopic and Related Surgery
July 2007
Intra-articular anesthesia and knee muscle response
Clinical Biomechanics
June 2007
The Meniscal Roots: Gross Anatomic Correlation with 3-T MRI Findings
American Journal of Roentgenology
May 2007
Assuming exponential decay by incorporating viscous damping improves the prediction of ...
Proceedings of the Institution of Mechanical Engineers Part H Journal of Engineering in...
March 2007
Effects of Initial Graft Tension on the Tibiofemoral Compressive Forces and Joint Posit...
The American Journal of Sports Medicine
March 2007
Frictional properties of Hartley guinea pig knees with and without proteolytic disrupti...
Osteoarthritis and Cartilage
March 2007
Accuracy of circular contact area measurements with thin-film pressure sensors
Journal of Biomechanics
January 2007
In Vitro Evaluation of the Effect Lateral Process Talar Excision on Ankle and Subtalar ...
Foot & Ankle International
January 2007
Quantification of meniscal volume by segmentation of 3T magnetic resonance images
Journal of Biomechanics
January 2007
Survey of Orthopaedic and Sports Medicine Physicians Regarding Use of Medrol Dosepak fo...
Arthroscopy The Journal of Arthroscopic and Related Surgery
December 2006
Compression Force and Laxity Differences Using Different Initial Graft Tensioning Techn...
Arthroscopy The Journal of Arthroscopic and Related Surgery
June 2006
In-Vitro Study of Hamstring Graft Morphometry and an Intraoperative Technique to Avoid ...
Arthroscopy The Journal of Arthroscopic and Related Surgery
June 2006
Free Communication/Poster – Fluid and Electrolyte Balance
Medicine & Science in Sports & Exercise
May 2006
Accurate Measurement of Cartilage Morphology Using a 3D Laser Scanner
January 2006
Material properties of articular cartilage in the rabbit tibial plateau
Journal of Biomechanics
January 2006
In vivo loads in the medial compartment of the rabbit knee
Clinical Biomechanics
November 2005
Treatment of Anterior Cruciate Ligament Injuries, Part 2
The American Journal of Sports Medicine
November 2005
Ligament injury, reconstruction and osteoarthritis
Current Opinion in Orthopedics
October 2005
Treatment of Anterior Cruciate Ligament Injuries, Part I
The American Journal of Sports Medicine
October 2005
Open- or Closed-Kinetic Chain Exercises After Anterior Cruciate Ligament Reconstruction?
Exercise and Sport Sciences Reviews
July 2005
Thumb carpometacarpal arthroscopy: A topographic, anatomic study of the thenar portal
The Journal Of Hand Surgery
March 2005
Rehabilitation after Anterior Cruciate Ligament Reconstruction: A Prospective, Randomiz...
The American Journal of Sports Medicine
March 2005
Strain on the Anterior Cruciate Ligament during Closed Kinetic Chain Exercises
Medicine & Science in Sports & Exercise
June 2004
In Vivo Measurement of Ligament/Tendon Strains and Forces: A Review
Annals of Biomedical Engineering
March 2004
The Effects of Compressive Load and Knee Joint Torque on Peak Anterior Cruciate Ligamen...
The American Journal of Sports Medicine
September 2003
The Effect of Anterior Cruciate Ligament Deficiency and Functional Bracing on Translati...
The American Journal of Sports Medicine
January 2003
The Science of Anterior Cruciate Ligament Rehabilitation
Clinical Orthopaedics and Related Research
September 2002
ANTERIOR CRUCIATE LIGAMENT REPLACEMENT: COMPARISON OF BONE-PATELLAR TENDON-BONE GRAFTS ...
Journal of Bone and Joint Surgery
September 2002
Erratum
Journal of Orthopaedic Research®
July 2002
Measurement of anterior–posterior knee laxity: a comparison of three techniques
Journal of Orthopaedic Research®
May 2002
Chronic anterior cruciate ligament deficiency is associated with increased anterior tra...
Journal of Orthopaedic Research®
March 2002
A new device to measure knee laxity during weightbearing and non-weightbearing conditions
Journal of Orthopaedic Research®
November 2001
The gastrocnemius muscle is an antagonist of the anterior cruciate ligament
Journal of Orthopaedic Research®
November 2001
Accuracy and repeatability of Roentgen stereophotogrammetric analysis (RSA) for measuri...
Journal of Biomechanics
October 2001
The relationship between graft tensioning and the anterior—posterior laxity in the ante...
Journal of Orthopaedic Research®
September 2001
The Elongation Behavior of the Anterior Cruciate Ligament Graft in Vivo
The American Journal of Sports Medicine
March 2001
The effect of weightbearing and external loading on anterior cruciate ligament strain
Journal of Biomechanics
February 2001
The Influence of Functional Knee Bracing on the Anterior Cruciate Ligament Strain Biome...
The American Journal of Sports Medicine
November 2000
Factors influencing the output of an implantable force transducer
Journal of Biomechanics
July 2000
Effects of Ultrasound and Stretch on Knee Ligament Extensibility
Journal of Orthopaedic and Sports Physical Therapy
June 2000
Pin Loosening in a Halo–Vest Orthosis
Spine
June 2000
The Strain Behavior of the Anterior Cruciate Ligament During Stair Climbing: An In Vivo...
Arthroscopy The Journal of Arthroscopic and Related Surgery
March 1999
Calibration and Application of an Intra-articular Force Transducer for the Measurement ...
Journal of Biomechanical Engineering
January 1999
Pin force measurement in a halo-vest orthosis, in vivo
Journal of Biomechanics
July 1998
The Effect of Screw Insertion Torque on Tendons Fixed with Spiked W...
The American Journal of Sports Medicine
July 1998
Anterior cruciate ligament strain in-vivo: A review of previous work
Journal of Biomechanics
June 1998
The Strain Behavior of the Anterior Cruciate Ligament During Bicycling
The American Journal of Sports Medicine
January 1998
The Strain Behavior of the Anterior Cruciate Ligament During Squatting and Active Flexi...
The American Journal of Sports Medicine
November 1997
The Effect of Functional Knee Bracing on the Anterior Cruciate Ligament in the Weightbe...
The American Journal of Sports Medicine
May 1997
Evaluation of Knee Joint Laxity and the Structural Properties of the Anterior Cruciate ...
The American Journal of Sports Medicine
March 1997
A Sagittal Plane Model of the Knee and Cruciate Ligaments With Application of a Sensiti...
Journal of Biomechanical Engineering
January 1996
Biomechanical analysis of the ankle anterior drawer test for anterior talofibular ligam...
Journal of Orthopaedic Research®
July 1995
Anterior Cruciate Ligament Strain Behavior During Rehabilitation Exercises In Vivo
The American Journal of Sports Medicine
January 1995
Determination of a zero strain reference for the anteromedial band of the anterior cruc...
Journal of Orthopaedic Research®
November 1994
An in vivo comparison between intraoperative isometric measurement and local elongation...
Journal of Bone and Joint Surgery
April 1994
The measurement of elongation of anterior cruciate-ligament grafts in vivo.
Journal of Bone and Joint Surgery
April 1994
Functional anatomy and biomechanics of the anterior cruciate ligament
Operative Techniques in Sports Medicine
January 1993
Isometric versus tension measurements
The American Journal of Sports Medicine
January 1993
An in vivo comparison of anterior tibial translation and strain in the anteromedial ban...
Journal of Biomechanics
January 1993
The effect of functional knee-braces on strain on the anterior cruciate ligament in vivo.
Journal of Bone and Joint Surgery
October 1992
External Fixator Pin Design
Clinical Orthopaedics and Related Research
May 1992
The measurement of anterior cruciate ligament strain in vivo
International Orthopaedics
March 1992
Effect of tension and placement of a prosthetic anterior cruciate ligament on the anter...
Journal of Orthopaedic Research®
March 1992
Anterior cruciate ligament reconstruction using quadriceps patellar tendon graft
The American Journal of Sports Medicine
September 1991
Anterior cruciate ligament reconstruction using quadriceps patellar tendon graft
The American Journal of Sports Medicine
September 1991
Effect of knee musculature on anterior cruciate ligament strain in vivo
Journal of Electromyography and Kinesiology
September 1991
Knee Biomechanics and Materials
January 1991
A method for the intravital measurement of interspinous kinematics
Journal of Biomechanics
January 1991
Reliability of Force/Displacement Measures in a Clinical Device Designed to Measure Lig...
Journal of Orthopaedic and Sports Physical Therapy
May 1989
Total knee arthroplasty kinematics
The Journal of Arthroplasty
October 1988
Comparative study of fracture gap motion in external fixation
Clinical Biomechanics
November 1987
