All Stories

  1. Suppression of toxicity of the mutant huntingtin protein by its interacting compound, desonide

    Article • Proceedings of the National Academy of Sciences, March 2022, Proceedings of the National Academy of Sciences

    Dr BOXUN LU

  2. HIPK3 modulates autophagy and HTT protein levels in neuronal and mouse models of Huntington disease

    Article • Autophagy, November 2017, Taylor & Francis

    Dr BOXUN LU

  3. NUB1 suppression of Huntington toxicity: mechanistic insights

    Article • Research and Reports in Biochemistry, May 2015, Dove Medical Press

    Dr BOXUN LU

  4. Gpr52 is a potential target for Huntington's disease and contributes to selective degeneration

    Article • eLife, March 2015, eLife

    Dr BOXUN LU

  5. TR-FRET Assays of Huntingtin Protein Fragments Reveal Temperature and PolyQ Length-Dependent Conformational Changes

    Article • Scientific Reports, July 2014, Springer Science + Business Media

    Dr BOXUN LU

  6. Drugging unconventional targets: insights from Huntington's disease

    Article • Trends in Pharmacological Sciences, February 2014, Elsevier

    Dr BOXUN LU

  7. High-throughput High-content Detection of Genetic Modifiers of Neurodegeneration in Human Stem Cell Derived Neurons

    Article • Protocol Exchange, November 2013, Springer Science + Business Media

    Dr BOXUN LU

  8. Identification of NUB1 as a suppressor of mutant Huntingtin toxicity via enhanced protein clearance

    Article • Nature Neuroscience, March 2013, Springer Science + Business Media

    Dr BOXUN LU

  9. A novel human embryonic stem cell‐derived Huntington's disease neuronal model exhibits mutant huntingtin (mHTT) aggregates and soluble mHTT‐dependent neurodegeneration

    Article • The FASEB Journal, January 2013, Wiley

    Dr BOXUN LU

  10. Extracellular Calcium Controls Background Current and Neuronal Excitability via an UNC79-UNC80-NALCN Cation Channel Complex

    Article • Neuron, November 2010, Elsevier

    Dr BOXUN LU

  11. Regulation of the NALCN Sodium Leak Channel by Neuropeptides

    Article • Biophysical Journal, February 2009, Elsevier

    Dr BOXUN LU

  12. Peptide neurotransmitters activate a cation channel complex of NALCN and UNC-80

    Article • Nature, December 2008, Springer Science + Business Media

    Dr BOXUN LU

  13. The Neuronal Channel NALCN Contributes Resting Sodium Permeability and Is Required for Normal Respiratory Rhythm

    Article • Cell, April 2007, Elsevier

    Dr BOXUN LU

  14. Inhibition of Na+ channel currents in rat myoblasts by 4-aminopyridine

    Article • Toxicology and Applied Pharmacology, September 2005, Elsevier

    Dr BOXUN LU

  15. Boundary Events: Contact-Dependent and Contact-Facilitated Signaling between Platelets

    Article • Seminars in Thrombosis and Hemostasis, August 2004, Thieme Publishing Group

    Dr BOXUN LU