All Stories

  1. A rapid CRISPR-based nanodroplet assay enables direct clinical identification of mycobacteria species

    Article • Science Translational Medicine, September 2026, American Association for the Advancement of Science

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  2. Direct delivery of assay reagents to extracellular vesicles in liquid biopsies for biomarker analysis

    Article • Nature Protocols, January 2026, Springer Science + Business Media

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  3. Hippocampal Bioenergetics and Metabolic Profiling Identifies Fatty Acid Oxidation as a Potential Therapeutic Target in Traumatic Brain Injury

    Article • Molecular Neurobiology, January 2026, Springer Science + Business Media

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  4. Sensitive pathogen DNA detection by a multi-guide RNA Cas12a assay favoring trans- versus cis-cleavage

    Article • Nature Communications, September 2025, Springer Science + Business Media

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  5. Self-powered rapid antigen-specific T-cell response assay for Mycobacterium tuberculosis infections

    Article • Nature Biomedical Engineering, June 2025, Springer Science + Business Media

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  6. Rapid tuberculosis diagnosis from respiratory or blood samples by a low cost, portable lab-in-tube assay

    Article • Science Translational Medicine, April 2025, American Association for the Advancement of Science

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  7. Precise mycobacterial species and subspecies identification using the PEP-TORCH peptidome algorithm

    Article • EMBO Molecular Medicine, March 2025, Springer Science + Business Media

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  8. CRISPR-mediated detection of Pneumocystis transcripts in bronchoalveolar, oropharyngeal, and serum specimens for Pneumocystis pneumonia diagnosis

    Article • Journal of Clinical Investigation, March 2025, American Society for Clinical Investigation

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  9. Applications of Nanotechnology for Spatial Omics: Biological Structures and Functions at Nanoscale Resolution

    Article • ACS Nano, December 2024, American Chemical Society (ACS)

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  10. Post‐COVID immunity in patients with solid tumor or hematological malignancies treated with SARS‐CoV‐2 monoclonal antibodies

    Article • Immunity Inflammation and Disease, December 2024, Wiley

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  11. Serum Cell-Free DNA-based Detection of Mycobacterium avium Complex Infection

    Article • American Journal of Respiratory and Critical Care Medicine, May 2024, American Thoracic Society

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  12. Improving Targeted Mass Spectrometry Data Analysis with Nested Active Machine Learning

    Article • Advanced Intelligent Systems, May 2024, Wiley

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  13. Mapping dynamic molecular changes in hippocampal subregions after traumatic brain injury through spatial proteomics

    Article • Clinical Proteomics, May 2024, Springer Science + Business Media

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  14. Altered COVID-19 immunity in children with asthma by atopic status

    Article • Journal of Allergy and Clinical Immunology Global, May 2024, Elsevier

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  15. Development of a CRISPR-Cas12a rapid diagnostic for human cytomegalovirus

    Article • Antiviral Research, July 2023, Elsevier

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  16. Chromatin-Accessible miRNA Regulons Driving Thyroid Tumorigenesis and Progression

    Article • Journal of the American College of Surgeons, January 2023, Wolters Kluwer Health

    Prof. Manal Said Fawzy, Bo Ning

  17. Evaluation of SARS-CoV-2-Specific T-Cell Activation with a Rapid On-Chip IGRA

    Article • ACS Nano, January 2023, American Chemical Society (ACS)

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  18. Extracellular vesicles: Emerging tools as therapeutic agent carriers

    Article • Acta Pharmaceutica Sinica B, October 2022, Elsevier

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  19. A miRNA-Based Prognostic Model to Trace Thyroid Cancer Recurrence

    Article • Cancers, August 2022, MDPI AG

    Prof. Manal Said Fawzy, Bo Ning

  20. Diagnosis of paediatric tuberculosis by optically detecting two virulence factors on extracellular vesicles in blood samples

    Article • Nature Biomedical Engineering, August 2022, Springer Science + Business Media

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  21. Understanding Immune‐Driven Brain Aging by Human Brain Organoid Microphysiological Analysis Platform

    Article • Advanced Science, July 2022, Wiley

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  22. CRISPR detection of circulating cell-free Mycobacterium tuberculosis DNA in adults and children, including children with HIV: a molecular diagnostics study

    Article • The Lancet Microbe, July 2022, Elsevier

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  23. Antibody Responses In Non-Severe SARS-CoV-2 Infections Are Driven By CD4+ T cells and Age

    Article • April 2022, Cold Spring Harbor Laboratory Press

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  24. Neuropathology and virus in brain of SARS-CoV-2 infected non-human primates

    Article • Nature Communications, April 2022, Springer Science + Business Media

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  25. CRISPR-based assay reveals SARS-CoV-2 RNA dynamic changes and redistribution patterns in non-human primate model

    Article • Emerging Microbes & Infections, February 2022, Taylor & Francis

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  26. Rapid detection of multiple SARS-CoV-2 variants of concern by PAM-targeting mutations

    Article • Cell Reports Methods, February 2022, Elsevier

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  27. Liposome-mediated detection of SARS-CoV-2 RNA-positive extracellular vesicles in plasma

    Article • Nature Physics, July 2021, Springer Science + Business Media

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  28. High mortality with High false negative rate: COVID-19 infection in patients with hematologic malignancies

    Article • Leukemia Research, July 2021, Elsevier

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  29. Evaluation of a serum-based antigen test for tuberculosis in HIV-exposed infants: a diagnostic accuracy study

    Article • BMC Medicine, May 2021, Springer Science + Business Media

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  30. Sensitive tracking of circulating viral RNA through all stages of SARS-CoV-2 infection

    Article • Journal of Clinical Investigation, April 2021, American Society for Clinical Investigation

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  31. A smartphone-read ultrasensitive and quantitative saliva test for COVID-19

    Article • Science Advances, January 2021, American Association for the Advancement of Science

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  32. Correction: The PorX/PorY system is a virulence factor of Porphyromonas gingivalis and mediates the activation of the type IX secretion system

    Article • Journal of Biological Chemistry, January 2021, Elsevier

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  33. The PorX/PorY system is a virulence factor of Porphyromonas gingivalis and mediates the activation of the type IX secretion system

    Article • Journal of Biological Chemistry, January 2021, Elsevier

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  34. Safety and efficacy of COVID‐19 convalescent plasma in severe pulmonary disease: A report of 17 patients

    Article • Transfusion Medicine, October 2020, Wiley

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  35. Ultra-sensitive and high-throughput CRISPR-p owered COVID-19 diagnosis

    Article • Biosensors and Bioelectronics, September 2020, Elsevier

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  36. Circulating levels of hydroxylated bradykinin function as an indicator of tissue HIF-1α expression

    Article • Science Bulletin, September 2020, Elsevier

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  37. Beclin 2 negatively regulates innate immune signaling and tumor development

    Article • Journal of Clinical Investigation, August 2020, American Society for Clinical Investigation

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  38. Neuropathology and Virus in Brain of SARS-CoV-2 Infected Non-Human Primates

    Article • August 2020, Springer Science + Business Media

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  39. COVID-19 in allogeneic stem cell transplant: high false-negative probability and role of CRISPR and convalescent plasma

    Article • British Journal of Pharmacology, June 2020, Springer Science + Business Media

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  40. Extracellular vesicle tetraspanin-8 level predicts distant metastasis in non–small cell lung cancer after concurrent chemoradiation

    Article • Science Advances, March 2020, American Association for the Advancement of Science

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  41. Cathepsin B Dependent Cleavage Product of Serum Amyloid A1 Identifies Patients with Chemotherapy-Related Cardiotoxicity

    Article • ACS Pharmacology & Translational Science, August 2019, American Chemical Society (ACS)

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  42. Tumor‐derived exosomes (TDEs): How to avoid the sting in the tail

    Article • Medicinal Research Reviews, July 2019, Wiley

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  43. Rapid Lipid-Based Approach for Normalization of Quantum-Dot-Detected Biomarker Expression on Extracellular Vesicles in Complex Biological Samples

    Article • Nano Letters, July 2019, American Chemical Society (ACS)

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  44. Nanotrap-enabled quantification of KRAS-induced peptide hydroxylation in blood for cancer early detection

    Article • Nano Research, May 2019, Tsinghua University Press

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  45. Extracellular vesicles as cancer liquid biopsies: from discovery, validation, to clinical application

    Article • Lab on a Chip, January 2019, Royal Society of Chemistry

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  46. Enhanced Natural Killer Cell Immunotherapy by Rationally Assembling Fc Fragments of Antibodies onto Tumor Membranes

    Article • Advanced Materials, December 2018, Wiley

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  47. PHF20 collaborates with PARP1 to promote stemness and aggressiveness of neuroblastoma cells through activation of SOX2 and OCT4

    Article • Journal of Molecular Cell Biology, March 2018, Oxford University Press (OUP)

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  48. Tgfbr2 inactivation facilitates cellular plasticity and development of Pten-null prostate cancer

    Article • Journal of Molecular Cell Biology, January 2018, Oxford University Press (OUP)

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  49. Chemoresistance Transmission via Exosome-Mediated EphA2 Transfer in Pancreatic Cancer

    Article • Theranostics, January 2018, Ivyspring International Publisher

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  50. USP26 functions as a negative regulator of cellular reprogramming by stabilising PRC1 complex components

    Article • Nature Communications, August 2017, Springer Science + Business Media

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  51. Circulating Peptidome and Tumor-Resident Proteolysis

    Article • January 2017, Elsevier

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  52. Drug Discovery via Human-Derived Stem Cell Organoids

    Article • Frontiers in Pharmacology, September 2016, Frontiers

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  53. Targeting epigenetic regulations in cancer

    Article • Acta Biochimica et Biophysica Sinica, January 2016, China Science Publishing & Media Ltd.

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  54. 5-Aza-2′-deoxycytidine Activates Iron Uptake and Heme Biosynthesis by Increasing c-Myc Nuclear Localization and Binding to the E-boxes of Transferrin Receptor 1 (TfR1) and Ferrochelatase (Fech) Genes

    Article • Journal of Biological Chemistry, October 2011, Elsevier

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  55. Ferroportin1 deficiency in mouse macrophages impairs iron homeostasis and inflammatory responses

    Article • Blood, August 2011, American Society of Hematology

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  56. Direct evidence for catalase and peroxidase activities of ferritin–platinum nanoparticles

    Article • Biomaterials, February 2011, Elsevier

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  57. Lysosomal Proteolysis Is the Primary Degradation Pathway for Cytosolic Ferritin and Cytosolic Ferritin Degradation Is Necessary for Iron Exit

    Article • Antioxidants & Redox Signaling, October 2010, Mary Ann Liebert Inc

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  58. Neuroprotective Mechanism of Mitochondrial Ferritin on 6-Hydroxydopamine–Induced Dopaminergic Cell Damage: Implication for Neuroprotection in Parkinson's Disease

    Article • Antioxidants & Redox Signaling, September 2010, Mary Ann Liebert Inc

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