All Stories

  1. Dual-specificity protein phosphatase 1: A potential therapeutic target in cancer

    Article • iScience, November 2025, Elsevier

    Professor Blaine Mooers

  2. Arginine demethylation of Serine/Arginine‐rich splicing factor 1 enhances miRNA enrichment in small extracellular vesicles derived from pancreatic ductal adenocarcinoma cells

    Article • The FASEB Journal, January 2025, Wiley

    Professor Blaine Mooers

  3. Targeting Oncogenic RET Kinase by Simultaneously Inhibiting Kinase Activity and Degrading the Protein

    Article • Journal of Medicinal Chemistry, December 2024, American Chemical Society (ACS)

    Professor Blaine Mooers

  4. Voice Computing with Python in Jupyter Notebooks

    Article • July 2024, NumFOCUS - Insight Software Consortium (ITK)

    Professor Blaine Mooers

  5. Adaptable SEC‐SAXS data collection for higher quality structure analysis in solution

    Article • Protein Science, March 2024, Wiley

    Professor Blaine Mooers

  6. Targeting RNA Structure to Inhibit Editing in Trypanosomes

    Article • International Journal of Molecular Sciences, June 2023, MDPI AG

    Professor Blaine Mooers

  7. Biomolecular Crystallographic Computing with Jupyter

    Article • January 2023, NumFOCUS - Insight Software Consortium (ITK)

    Professor Blaine Mooers

  8. Mutated KLF4(K409Q) in meningioma binds STRs and activates FGF3 gene expression

    Article • iScience, August 2022, Elsevier

    Professor Blaine Mooers

  9. Coupling of acceptor-substituted diazo compounds and tertiary thioamides: synthesis of enamino carbonyl compounds and their pharmacological evaluation

    Article • RSC Advances, January 2022, Royal Society of Chemistry

    Professor Blaine Mooers

  10. Precision therapy for RET-altered cancers with RET inhibitors

    Article • Trends in Cancer, December 2021, Elsevier

    Professor Blaine Mooers

  11. Engineering Crystal Packing in RNA Structures I: Past and Future Strategies for Engineering RNA Packing in Crystals

    Article • Crystals, August 2021, MDPI AG

    Professor Blaine Mooers

  12. Simulations of Promising Indolizidine—α6-β2 Nicotinic Acetylcholine Receptor Complexes

    Article • International Journal of Molecular Sciences, July 2021, MDPI AG

    Professor Blaine Mooers

  13. The L730V/I RET roof mutations display different activities toward pralsetinib and selpercatinib

    Article • npj Precision Oncology, June 2021, Springer Science + Business Media

    Professor Blaine Mooers

  14. Patient-driven discovery and post-clinical validation of NTRK3 fusion as an acquired resistance mechanism to selpercatinib in RET fusion-positive lung cancer

    Article • Annals of Oncology, June 2021, Elsevier

    Professor Blaine Mooers

  15. A PyMOL Snippet Library for Jupyter to Boost Researcher Productivity

    Article • Computing in Science & Engineering, March 2021, Institute of Electrical & Electronics Engineers (IEEE)

    Professor Blaine Mooers

  16. Structural basis of acquired resistance to selpercatinib and pralsetinib mediated by non-gatekeeper RET mutations

    Article • Annals of Oncology, February 2021, Elsevier

    Professor Blaine Mooers

  17. Modernizing computing by structural biologists with Jupyter and Colab

    Article • January 2021, NumFOCUS - Insight Software Consortium (ITK)

    Professor Blaine Mooers

  18. Templates for Writing PyMOL Scripts

    Article • Protein Science, November 2020, Wiley

    Professor Blaine Mooers

  19. SRSF1 regulates exosome microRNA enrichment in human cancer cells

    Article • Cell Communication and Signaling, August 2020, Springer Science + Business Media

    Professor Blaine Mooers

  20. RET kinase alterations in targeted cancer therapy

    Article • January 2020, OAE Publishing

    Professor Blaine Mooers

  21. Shortcuts ease and enhance productivity with the molecular graphic program PyMOL

    Article • Protein Science, November 2019, Wiley

    Professor Blaine Mooers

  22. Structural basis of resistance of mutant RET protein-tyrosine kinase to its inhibitors nintedanib and vandetanib

    Article • Journal of Biological Chemistry, May 2019, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Blaine Mooers

  23. Protein features for assembly of the RNA editing helicase 2 subcomplex (REH2C) in Trypanosome holo-editosomes

    Article • PLOS One, April 2019, PLOS

    Professor Blaine Mooers

  24. Protein features for assembly of the RNA editing helicase 2 subcomplex (REH2C) in Trypanosome holo-editosomes

    Article • January 2019, Cold Spring Harbor Laboratory Press

    Professor Blaine Mooers

  25. Dynamic RNA holo-editosomes with subcomplex variants: Insights into the control of trypanosome editing

    Article • Wiley Interdisciplinary Reviews - RNA, August 2018, Wiley

    Professor Blaine Mooers

  26. Drug resistance profiles of mutations in the RET kinase domain

    Article • British Journal of Pharmacology, July 2018, Wiley

    Professor Blaine Mooers

  27. Simplifying and enhancing the use of PyMOL with horizontal scripts

    Article • Protein Science, August 2016, Wiley

    Professor Blaine Mooers

  28. DEAH-RHA helicase•Znf cofactor systems in kinetoplastid RNA editing and evolutionarily distant RNA processes

    Article • RNA & DISEASE, June 2016, Smart Science and Technology, LLC

    Professor Blaine Mooers

  29. Direct-methods structure determination of a trypanosome RNA-editing substrate fragment with translational pseudosymmetry

    Article • Acta Crystallographica Section D Structural Biology, March 2016, International Union of Crystallography

    Professor Blaine Mooers

  30. REH2C Helicase and GRBC Subcomplexes May Base Pair through mRNA and Small Guide RNA in Kinetoplastid Editosomes

    Article • Journal of Biological Chemistry, January 2016, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Blaine Mooers

  31. Structures and Energetics of Four Adjacent G·U Pairs That Stabilize an RNA Helix

    Article • The Journal of Physical Chemistry B, October 2015, American Chemical Society (ACS)

    Professor Blaine Mooers

  32. Human γ-Glutamyl Transpeptidase 1

    Article • Journal of Biological Chemistry, May 2015, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Blaine Mooers

  33. Native Variants of the MRB1 Complex Exhibit Specialized Functions in Kinetoplastid RNA Editing

    Article • PLOS One, April 2015, PLOS

    Professor Blaine Mooers

  34. Fusion RNAs in Crystallographic Studies of Double-Stranded RNA from Trypanosome RNA Editing

    Article • October 2014, Springer Science + Business Media

    Professor Blaine Mooers

  35. Structural Studies of a Double-Stranded RNA from Trypanosome RNA Editing by Small-Angle X-Ray Scattering

    Article • October 2014, Springer Science + Business Media

    Professor Blaine Mooers

  36. Native mitochondrial RNA-binding complexes in kinetoplastid RNA editing differ in guide RNA composition

    Article • RNA, May 2014, Cold Spring Harbor Laboratory Press

    Professor Blaine Mooers

  37. Novel insights into eukaryotic γ-glutamyltranspeptidase 1 from the crystal structure of the glutamate-bound human enzyme.

    Article • Journal of Biological Chemistry, April 2014, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Blaine Mooers

  38. After Embedding in Membranes Antiapoptotic Bcl-XL Protein Binds Both Bcl-2 Homology Region 3 and Helix 1 of Proapoptotic Bax Protein to Inhibit Apoptotic Mitochondrial Permeabilization

    Article • Journal of Biological Chemistry, March 2014, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Blaine Mooers

  39. Glycosylation of Skp1 Affects Its Conformation and Promotes Binding to a Model F-Box Protein

    Article • Biochemistry, March 2014, American Chemical Society (ACS)

    Professor Blaine Mooers

  40. Novel Insights into Eukaryotic γ-Glutamyltranspeptidase 1 from the Crystal Structure of the Glutamate-bound Human Enzyme

    Article • Journal of Biological Chemistry, September 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Blaine Mooers

  41. Crystal structure of a new benzoic acid inhibitor of influenza neuraminidase bound with a new tilt induced by overpacking subsite C6

    Article • BMC Structural Biology, January 2012, Springer Science + Business Media

    Professor Blaine Mooers

  42. The crystal structure of an oligo(U):pre-mRNA duplex from a trypanosome RNA editing substrate

    Article • RNA, August 2011, Cold Spring Harbor Laboratory Press

    Professor Blaine Mooers

  43. Contributions of all 20 amino acids at site 96 to the stability and structure of T4 lysozyme

    Article • Protein Science, May 2009, Wiley

    Professor Blaine Mooers

  44. Evaluation at atomic resolution of the role of strain in destabilizing the temperature-sensitive T4 lysozyme mutant Arg 96 → His

    Article • Protein Science, May 2009, Wiley

    Professor Blaine Mooers

  45. Crystallographic studies of DNA and RNA

    Article • Methods, March 2009, Elsevier

    Professor Blaine Mooers

  46. Largest protein structure determined to date by traditional ab initio direct methods

    Article • Acta Crystallographica Section D Biological Crystallography, January 2006, International Union of Crystallography

    Professor Blaine Mooers

  47. The structural basis of myotonic dystrophy from the crystal structure of CUG repeats

    Article • Proceedings of the National Academy of Sciences, November 2005, Proceedings of the National Academy of Sciences

    Professor Blaine Mooers

  48. Use of an ion-binding site to bypass the 1000-atom limit to structure determination by direct methods

    Article • Acta Crystallographica Section D Biological Crystallography, September 2004, International Union of Crystallography

    Professor Blaine Mooers

  49. Relocation or Duplication of the Helix A Sequence of T4 Lysozyme Causes Only Modest Changes in Structure but Can Increase or Decrease the Rate of Folding†

    Article • Biochemistry, February 2004, American Chemical Society (ACS)

    Professor Blaine Mooers

  50. Repacking the Core of T4 Lysozyme by Automated Design

    Article • Journal of Molecular Biology, September 2003, Elsevier

    Professor Blaine Mooers

  51. Multiple methionine substitutions are tolerated in T4 lysozyme and have coupled effects on folding and stability

    Article • Biophysical Chemistry, December 2002, Elsevier

    Professor Blaine Mooers

  52. The crystal structures of psoralen cross-linked DNAs: drug-dependent formation of Holliday junctions11Edited by I. Tinoco

    Article • Journal of Molecular Biology, April 2001, Elsevier

    Professor Blaine Mooers

  53. The Holliday junction in an inverted repeat DNA sequence: Sequence effects on the structure of four-way junctions

    Article • Proceedings of the National Academy of Sciences, April 2000, Proceedings of the National Academy of Sciences

    Professor Blaine Mooers

  54. The structures and relative stabilities of d(G · G) reverse hoogsteen, d(G·T) reverse wobble, and d(G · C) reverse watson-crick base-pairs in DNA crystals 1 1Edited by I. Tinoco

    Article • Journal of Molecular Biology, July 1997, Elsevier

    Professor Blaine Mooers

  55. Z-DNA crystallography

    Article • Biopolymers, January 1997, Wiley

    Professor Blaine Mooers

  56. Alternating and Non-alternating dG-dC Hexanucleotides Crystallize as CanonicalA-DNA

    Article • Journal of Molecular Biology, June 1995, Elsevier

    Professor Blaine Mooers

  57. Fescue Grasses of Canada, by S. G. Aiken and S. J. Darbyshire [Review]

    Article • The Canadian Field-Naturalist, January 1991, Biodiversity Heritage Library

    Professor Blaine Mooers

  58. Mathematical Modling in Ecology: A Workbook for Students, by Clark Jeffries [Review]

    Article • The Canadian Field-Naturalist, January 1991, Biodiversity Heritage Library

    Professor Blaine Mooers

  59. Matrix Population Models: Construction, Analysis, and Interpretation, by Hal Caswell [Review]

    Article • The Canadian Field-Naturalist, January 1991, Biodiversity Heritage Library

    Professor Blaine Mooers

  60. Population Ecology of Individuals, by Adam Lomnicki [Review]

    Article • The Canadian Field-Naturalist, January 1990, Biodiversity Heritage Library

    Professor Blaine Mooers

  61. State of Washington Natural Heritage Plan, by Washington Natural Heritage Program [Review]

    Article • The Canadian Field-Naturalist, January 1990, Biodiversity Heritage Library

    Professor Blaine Mooers

  62. Individuals, Populations, and Communities, by Michael Begon, John L. Harper, and Colin R. Townsend [Review]

    Article • The Canadian Field-Naturalist, January 1989, Biodiversity Heritage Library

    Professor Blaine Mooers

  63. Plant Strategies and the Dynamics and Structure of Plant Communities, by David Tilman [Review]

    Article • The Canadian Field-Naturalist, January 1989, Biodiversity Heritage Library

    Professor Blaine Mooers

  64. Population Ecology: A Unified Study of Animals and Plants, by Michael Begon and Martin Mortimer [Review]

    Article • The Canadian Field-Naturalist, January 1989, Biodiversity Heritage Library

    Professor Blaine Mooers

  65. Restoration Ecology: A Synthetic Approach to Ecological Research, eds. William R. Jordan III, Michael E. Gilpin, and John D. Aber [Review]

    Article • The Canadian Field-Naturalist, January 1989, Biodiversity Heritage Library

    Professor Blaine Mooers

  66. Sustainable Development of the Biosphere, eds. William C. Clark and R. E. Munn [Review]

    Article • The Canadian Field-Naturalist, January 1989, Biodiversity Heritage Library

    Professor Blaine Mooers

  67. The Savannas: Biogeography and Geobotany, by Monica M. Cole [Review]

    Article • The Canadian Field-Naturalist, January 1988, Biodiversity Heritage Library

    Professor Blaine Mooers