All Stories

  1. The high catalytic rate of the cold‐activeVibrioalkaline phosphatase requires a hydrogen bonding network involving a large interface loop

    Article • FEBS Open Bio, December 2020, Wiley

    Mr Bjarni Asgeirsson

  2. X-ray crystal structure of Vibrio alkaline phosphatase with the non-competitive inhibitor cyclohexylamine

    Article • Biochemistry and Biophysics Reports, December 2020, Elsevier

    Mr Bjarni Asgeirsson

  3. Chloride promotes refolding of active Vibrio alkaline phosphatase through an inactive dimeric intermediate with an altered interface

    Article • FEBS Open Bio, December 2018, Wiley

    Mr Bjarni Asgeirsson

  4. pH-Dependent Binding of Chloride to a Marine Alkaline Phosphatase Affects the Catalysis, Active Site Stability, and Dimer Equilibrium

    Article • Biochemistry, September 2017, American Chemical Society (ACS)

    Mr Bjarni Asgeirsson

  5. Cold-active alkaline phosphatase is irreversibly transformed into an inactive dimer by low urea concentrations

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, July 2016, Elsevier

    Mr Bjarni Asgeirsson

  6. The PDB database is a rich source of alpha-helical anti-microbial peptides to combat disease causing pathogens

    Article • F1000Research, June 2015, Faculty of 1000, Ltd.

    Mr Bjarni Asgeirsson

  7. The dipeptidyl peptidase IV inhibitors vildagliptin and K-579 inhibit a phospholipase C: a case of promiscuous scaffolds in proteins

    Article • F1000Research, January 2015, Faculty of 1000, Ltd.

    Mr Bjarni Asgeirsson

  8. Characterizing alpha helical properties of Ebola viral proteins as potential targets for inhibition of alpha-helix mediated protein-protein interactions

    Article • F1000Research, January 2015, Faculty of 1000, Ltd.

    Mr Bjarni Asgeirsson

  9. Dipeptidyl peptidase-IV inhibitors used in type-2 diabetes inhibit a phospholipase C: a case of promiscuous scaffolds in proteins

    Article • F1000Research, January 2015, Faculty of 1000, Ltd.

    Mr Bjarni Asgeirsson

  10. Correlating the ability of VP24 protein from Ebola and Marburg viruses to bind human karyopherin to their immune suppression mechanism and pathogenicity using computational methods

    Article • F1000Research, December 2014, Faculty of 1000, Ltd.

    Mr Bjarni Asgeirsson

  11. Alpha-helical anti-microbial peptides

    Article • F1000Research, December 2014, Faculty of 1000, Ltd.

    Professor Abhaya M Dandekar, Mr Bjarni Asgeirsson

  12. Characterizing alpha helical properties of Ebola viral proteins as potential targets for inhibition of alpha-helix mediated protein-protein interactions

    Article • F1000Research, November 2014, Faculty of 1000, Ltd.

    Mr Bjarni Asgeirsson

  13. Correlating the ability of VP24 protein from Ebola and Marburg viruses to bind human karyopherin to their immune suppression mechanism and pathogenicity using computational methods

    Article • F1000Research, November 2014, Faculty of 1000, Ltd.

    Professor Abhaya M Dandekar, Mr Bjarni Asgeirsson

  14. Characterizing alpha helical properties of Ebola viral proteins as potential targets for inhibition of alpha-helix mediated protein-protein interactions

    Article • F1000Research, October 2014, Faculty of 1000, Ltd.

    Professor Abhaya M Dandekar, Mr Bjarni Asgeirsson

  15. The electrostatic profile of consecutive Cβ atoms applied to protein structure quality assessment

    Article • F1000Research, September 2014, Faculty of 1000, Ltd.

    Mr Bjarni Asgeirsson

  16. PREMONITION - Preprocessing motifs in protein structures for search acceleration

    Article • F1000Research, September 2014, Faculty of 1000, Ltd.

    Professor Abhaya M Dandekar, Mr Bjarni Asgeirsson

  17. Directed evolution induces tributyrin hydrolysis in a virulence factor of Xylella fastidiosa using a duplicated gene as a template

    Article • F1000Research, September 2014, Faculty of 1000, Ltd.

    Professor Abhaya M Dandekar, Mr Bjarni Asgeirsson

  18. Promiscuous scaffolds in proteins - non-native, non-additive and non-trivial

    Article • F1000Research, January 2014, Faculty of 1000, Ltd.

    Mr Bjarni Asgeirsson

  19. Dipeptidyl peptidase-IV inhibitors used in type-2 diabetes inhibit a phospholipase C: a case of promiscuous scaffolds in proteins

    Article • F1000Research, December 2013, Faculty of 1000, Ltd.

    Mr Bjarni Asgeirsson

  20. Protein structure quality assessment based on the distance profiles of consecutive backbone Cα atoms

    Article • F1000Research, December 2013, F1000Research

    Mr Bjarni Asgeirsson

  21. Promiscuous scaffolds in proteins - non-native, non-additive and non-trivial

    Article • F1000Research, November 2013, Faculty of 1000, Ltd.

    Professor Abhaya M Dandekar, Mr Bjarni Asgeirsson, Professor Jean-Marie A FRERE, Ade Rendon

  22. Protein structure quality assessment based on the distance profiles of consecutive backbone Cα atoms

    Article • F1000Research, November 2013, F1000Research

    Mr Bjarni Asgeirsson

  23. The electrostatic profile of consecutive Cβ atoms applied to protein structure quality assessment

    Article • F1000Research, November 2013, Faculty of 1000, Ltd.

    Mr Bjarni Asgeirsson

  24. The electrostatic profile of consecutive Cβ atoms applied to protein structure quality assessment

    Article • F1000Research, November 2013, Faculty of 1000, Ltd.

    Professor Abhaya M Dandekar, Mr Bjarni Asgeirsson

  25. Protein structure quality assessment based on the distance profiles of consecutive backbone Cα atoms

    Article • F1000Research, October 2013, Faculty of 1000, Ltd.

    Professor Abhaya M Dandekar, Mr Bjarni Asgeirsson

  26. A Computational Module Assembled from Different Protease Family Motifs Identifies PI PLC from Bacillus cereus as a Putative Prolyl Peptidase with a Serine Protease Scaffold

    Article • PLOS One, August 2013, PLOS

    Mr Bjarni Asgeirsson

  27. Dynamics fingerprint and inherent asymmetric flexibility of a cold-adapted homodimeric enzyme. A case study of the Vibrio alkaline phosphatase

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, April 2013, Elsevier

    Mr Bjarni Asgeirsson

  28. Structural phylogeny by profile extraction and multiple superimposition using electrostatic congruence as a discriminator

    Article • Intrinsically Disordered Proteins, January 2013, Taylor & Francis

    Mr Bjarni Asgeirsson

  29. A Measure of the Broad Substrate Specificity of Enzymes Based on ‘Duplicate’ Catalytic Residues

    Article • PLOS One, November 2012, PLOS

    Mr Bjarni Asgeirsson

  30. Nervonic Acid (24:1n-9) is a Dominant Unsaturated Fatty Acid in the Intestinal Brush Border of Atlantic Cod

    Article • Lipid Insights, October 2012, Libertas Academica, Ltd.

    Mr Bjarni Asgeirsson

  31. Inhibition of a cold-active alkaline phosphatase by imipenem revealed by in silico modeling of metallo-β-lactamase active sites

    Article • FEBS Letters, September 2012, Wiley

    Mr Bjarni Asgeirsson

  32. Isolation and biochemical characterisation of lipid rafts from Atlantic cod (Gadus morhua) intestinal enterocytes

    Article • Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology, January 2010, Elsevier

    Mr Bjarni Asgeirsson

  33. The 1.4 A crystal structure of the large and cold-active Vibrio sp. alkaline phosphatase

    Article • June 2009, Protein Data Bank, Rutgers University

    Mr Bjarni Asgeirsson

  34. Structural features and dynamics of a cold-adapted alkaline phosphatase studied by EPR spectroscopy

    Article • FEBS Journal, May 2009, Wiley

    Mr Bjarni Asgeirsson

  35. The 1.4 Å crystal structure of the large and cold-active Vibrio sp. alkaline phosphatase

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, February 2009, Elsevier

    Mr Bjarni Asgeirsson

  36. Effects of replacing active site residues in a cold-active alkaline phosphatase with those found in its mesophilic counterpart from Escherichia coli

    Article • FEBS Journal, December 2007, Wiley

    Mr Bjarni Asgeirsson

  37. Engineered disulfide bonds increase active-site local stability and reduce catalytic activity of a cold-adapted alkaline phosphatase

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, June 2007, Elsevier

    Mr Bjarni Asgeirsson

  38. Microscopic rate-constants for substrate binding and acylation in cold-adaptation of trypsin I from Atlantic cod

    Article • FEBS Letters, July 2006, Wiley

    Mr Bjarni Asgeirsson

  39. Reversible inactivation of alkaline phosphatase from Atlantic cod (Gadus morhua) in urea

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, February 2006, Elsevier

    Mr Bjarni Asgeirsson

  40. Amino acid sequence of the cold-active alkaline phosphatase from Atlantic cod (Gadus morhua)

    Article • Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology, September 2003, Elsevier

    Mr Bjarni Asgeirsson

  41. Properties of Extremophilic Enzymes and Their Importance in Food Science and Technology

    Article • December 2002, Taylor & Francis

    Mr Bjarni Asgeirsson

  42. Primary structure of cold-adapted alkaline phosphatase from a Vibrio sp. as deduced from the nucleotide gene sequence

    Article • Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, September 2001, Elsevier

    Mr Bjarni Asgeirsson

  43. Dissociation and unfolding of cold-active alkaline phosphatase from Atlantic cod in the presence of guanidinium chloride

    Article • FEBS Journal, November 2000, Wiley

    Mr Bjarni Asgeirsson

  44. Alkaline phosphatase from a marine Vibrio sp.: Heat-lability coincides with high catalytic efficiency

    Article • Biochemical Society Transactions, October 2000, Portland Press Ltd.

    Mr Bjarni Asgeirsson

  45. Heat-labile bacterial alkaline phosphatase from a marine Vibrio sp.

    Article • Enzyme and Microbial Technology, July 2000, Elsevier

    Mr Bjarni Asgeirsson

  46. The third serine proteinase with chymotrypsin specificity isolated from Atlantic cod (Gadus morhua) is a type-II elastase

    Article • FEBS Journal, August 1998, Wiley

    Mr Bjarni Asgeirsson

  47. Hereditary cystatin C amyloid angiopathy: monitoring the presence of the Leu-68→Gln cystatin C variant in cerebrospinal fluids and monocyte cultures by MS

    Article • Biochemical Journal, February 1998, Portland Press Ltd.

    Mr Bjarni Asgeirsson

  48. Serine Proteinases from Cold-Adapted Organisms

    Article • January 1997, Springer Science + Business Media

    Mr Bjarni Asgeirsson

  49. Structure of chymotrypsin variant B from Atlantic cod, Gadus morhua

    Article • Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, September 1996, Elsevier

    Mr Bjarni Asgeirsson

  50. Alkaline phosphatase from Atlantic cod (Gadus morhua). Kinetic and structural properties which indicate adaptation to low temperatures

    Article • Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology, February 1995, Elsevier

    Mr Bjarni Asgeirsson

  51. Psychrophilic Proteinases from Atlantic Cod

    Article • December 1993, American Chemical Society (ACS)

    Mr Bjarni Asgeirsson

  52. Properties of elastase from Atlantic cod a cold-adapted proteinase

    Article • Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, June 1993, Elsevier

    Mr Bjarni Asgeirsson

  53. Characteristics, protein engineering and applications of psychrophilic marine proteinases from Atlantic cod

    Article • January 1993, Elsevier

    Mr Bjarni Asgeirsson

  54. On the role of monocytes/macrophages in the pathogenesis of central nervous system lesions in hereditary cystatin C amyloid angiopathy

    Article • Journal of the Neurological Sciences, April 1992, Elsevier

    Mr Bjarni Asgeirsson

  55. The characteristics of macrophage-like cell lines derived from normal sheep spleens

    Article • FEMS Microbiology Letters, December 1991, Oxford University Press (OUP)

    Mr Bjarni Asgeirsson

  56. The characteristics of macrophage-like cell lines derived from normal sheep spleens

    Article • FEMS Microbiology Letters, December 1991, Oxford University Press (OUP)

    Mr Bjarni Asgeirsson

  57. Isolation, Characterization and Utilization of Psychrophilic Proteinases from Atlantic Cod

    Article • January 1991, Springer Science + Business Media

    Mr Bjarni Asgeirsson

  58. Structural and kinetic properties of chymotrypsin from atlantic cod (Gadus morhua). Comparison with bovine chymotrypsin

    Article • Comparative Biochemistry and Physiology Part B Comparative Biochemistry, January 1991, Elsevier

    Mr Bjarni Asgeirsson

  59. Perturbation of processing of cystatin C in monocytes from patients with hereditary cystatin C amyloid angiopathy

    Article • January 1991, Springer Science + Business Media

    Mr Bjarni Asgeirsson

  60. Purification and characterization of trypsin from the poikilotherm Gadus morhua

    Article • FEBS Journal, March 1989, Wiley

    Mr Bjarni Asgeirsson

  61. Calcium-dependent protein phosphorylation in bovine anterior pituitary membranes and intact cells

    Article • Molecular and Cellular Endocrinology, March 1984, Elsevier

    Mr Bjarni Asgeirsson