All Stories

  1. Structural and functional insights into an archaealL-asparaginase obtained through the linker-less assembly of constituent domains. Corrigendum
  2. l-Asparaginase as a new molecular target against leishmaniasis: insights into the mechanism of action and structure-based inhibitor design
  3. Structural and functional insights into an archaealL-asparaginase obtained through the linker-less assembly of constituent domains
  4. Selective Interception of Gelsolin Amyloidogenic Stretch Results in Conformationally Distinct Aggregates with Reduced Toxicity
  5. Thermodynamic Stabilization of the Folded Domain of Prion Protein Inhibits Prion Infection in Vivo
  6. Part of a large protein helps in preventing aggregation of many other proteins
  7. Hyperthermophilic asparaginase mutants with enhanced substrate affinity and antineoplastic activity: structural insights on their mechanism of action
  8. Structural stability and functional analysis of L-asparaginase from Pyrococcus furiosus
  9. Prion metal interaction: Is prion pathogenesis a cause or a consequence of metal imbalance?
  10. Formation of amyloid fibrils by bovine carbonic anhydrase
  11. Interplay between DtxR and nitric oxide reductase activities: a functional genomics approach indicating involvement of homologous protein domains in bacterial pathogenesis
  12. Modulation of Proteinase K-resistant Prion Protein in Cells and Infectious Brain Homogenate by Redox Iron: Implications for Prion Replication and Disease Pathogenesis
  13. Predicting alternate structure attainment and amyloidogenesis: A nonlinear signal analysis approach
  14. The excised heat-shock domain of αB crystallin is a folded, proteolytically susceptible trimer with significant surface hydrophobicity and a tendency to self-aggregate upon heating
  15. Nucleation-dependent conformational conversion of the Y145Stop variant of human prion protein: Structural clues for prion propagation
  16. Peptide scanning-based identification of regions of γ-II crystallin involved in thermal aggregation: Evidence of the involvement of structurally analogous, helix-containing loops from the two double Greek key domains of the molecule
  17. Use of a hydrophobic dye to indirectly probe the structural organization and conformational plasticity of molecules in amorphous aggregates of carbonic anhydrase
  18. Manipulation of Unfolding-Induced Protein Aggregation by Peptides Selected for Aggregate-Binding Ability through Phage Display Library Screening
  19. Hydrophobic dye inhibits aggregation of molten carbonic anhydrase during thermal unfolding and refolding