All Stories

  1. Herpesvirus-mediated stabilization of ICP0 expression neutralizes restriction by TRIM23

    Article • Proceedings of the National Academy of Sciences, December 2021, Proceedings of the National Academy of Sciences

    Professor Bin He

  2. Oncolytic HSV: Underpinnings of Tumor Susceptibility

    Article • Viruses, July 2021, MDPI AG

    Professor Bin He

  3. The herpesvirus accessory protein γ134.5 facilitates viral replication by disabling mitochondrial translocation of RIG-I

    Article • PLoS Pathogens, March 2021, PLOS

    Professor Bin He

  4. Disassembly of the TRIM23-TBK1 Complex by the Us11 Protein of Herpes Simplex Virus 1 Impairs Autophagy

    Article • Journal of Virology, September 2019, ASM Journals

    Professor Bin He

  5. Selective Editing of Herpes Simplex Virus 1 Enables Interferon Induction and Viral Replication That Destroy Malignant Cells

    Article • Journal of Virology, November 2018, ASM Journals

    Professor Bin He

  6. Herpes Simplex Virus 1 γ134.5 Protein Inhibits STING Activation That Restricts Viral Replication

    Article • Journal of Virology, July 2018, ASM Journals

    Professor Bin He

  7. Herpes Simplex Virus 1 Inhibits TANK-Binding Kinase 1 through Formation of the Us11-Hsp90 Complex

    Article • Journal of Virology, May 2018, ASM Journals

    Professor Bin He

  8. Enterovirus 3A Facilitates Viral Replication by Promoting Phosphatidylinositol 4-Kinase IIIβ–ACBD3 Interaction

    Article • Journal of Virology, July 2017, ASM Journals

    Dr Jianwei Wang, Professor Bin He

  9. Enterovirus 71 Inhibits Pyroptosis through Cleavage of Gasdermin D

    Article • Journal of Virology, July 2017, ASM Journals

    Dr Jianwei Wang, Professor Bin He

  10. The Golgi protein ACBD3 facilitates Enterovirus 71 replication by interacting with 3A

    Article • Scientific Reports, March 2017, Springer Science + Business Media

    Professor Bin He

  11. An Engineered Herpesvirus Activates Dendritic Cells and Induces Protective Immunity

    Article • Scientific Reports, February 2017, Springer Science + Business Media

    Professor Bin He

  12. Herpes Simplex Virus 1 Induces Phosphorylation and Reorganization of Lamin A/C through the γ134.5 Protein That Facilitates Nuclear Egress

    Article • Journal of Virology, September 2016, ASM Journals

    Professor Bin He

  13. 3C Protease of Enterovirus D68 Inhibits Cellular Defense Mediated by Interferon Regulatory Factor 7

    Article • Journal of Virology, November 2015, ASM Journals

    Dr Jianwei Wang, Professor Bin He

  14. Reciprocal Regulation between Enterovirus 71 and the NLRP3 Inflammasome

    Article • Cell Reports, July 2015, Elsevier

    Professor Bin He

  15. The Us3 Protein of Herpes Simplex Virus 1 Inhibits T Cell Signaling by Confining Linker for Activation of T Cells (LAT) Activation via TRAF6 Protein

    Article • Journal of Biological Chemistry, June 2015, Elsevier

    Professor Bin He

  16. Herpes Simplex Virus 1 Suppresses the Function of Lung Dendritic Cells via Caveolin-1

    Article • Clinical and Vaccine Immunology, May 2015, ASM Journals

    Professor Bin He

  17. p32 Is a Novel Target for Viral Protein ICP34.5 of Herpes Simplex Virus Type 1 and Facilitates Viral Nuclear Egress

    Article • Journal of Biological Chemistry, December 2014, Elsevier

    Professor Bin He

  18. Enterovirus 71 3C Inhibits Cytokine Expression through Cleavage of the TAK1/TAB1/TAB2/TAB3 Complex

    Article • Journal of Virology, June 2014, ASM Journals

    Dr Jianwei Wang, Professor Bin He

  19. Enterovirus 68 3C Protease Cleaves TRIF To Attenuate Antiviral Responses Mediated by Toll-Like Receptor 3

    Article • Journal of Virology, March 2014, ASM Journals

    Dr Jianwei Wang, Professor Bin He

  20. Recognition of Herpes Simplex Viruses: Toll-Like Receptors and Beyond

    Article • Journal of Molecular Biology, March 2014, Elsevier

    Professor Bin He

  21. TRIM14 is a mitochondrial adaptor that facilitates retinoic acid-inducible gene-I–like receptor-mediated innate immune response

    Article • Proceedings of the National Academy of Sciences, December 2013, Proceedings of the National Academy of Sciences

    Professor Bin He

  22. Cleavage of Interferon Regulatory Factor 7 by Enterovirus 71 3C Suppresses Cellular Responses

    Article • Journal of Virology, November 2012, ASM Journals

    Dr Jianwei Wang, Professor Bin He

  23. The Akt1 Isoform Is Required for Optimal IFN-β Transcription through Direct Phosphorylation of β-Catenin

    Article • The Journal of Immunology, August 2012, The American Association of Immunologists

    Professor Bin He

  24. Inhibition of TANK Binding Kinase 1 by Herpes Simplex Virus 1 Facilitates Productive Infection

    Article • Journal of Virology, December 2011, ASM Journals

    Professor Bin He

  25. Activation of NF- B in CD8+ Dendritic Cells Ex Vivo by the  134.5 Null Mutant Correlates with Immunity against Herpes Simplex Virus 1

    Article • Journal of Virology, November 2011, ASM Journals

    Professor Bin He

  26. Activation of Autophagy by α-Herpesviruses in Myeloid Cells Is Mediated by Cytoplasmic Viral DNA through a Mechanism Dependent on Stimulator of IFN Genes

    Article • The Journal of Immunology, October 2011, The American Association of Immunologists

    Professor Bin He

  27. A Herpesvirus Virulence Factor Inhibits Dendritic Cell Maturation through Protein Phosphatase 1 and I B Kinase

    Article • Journal of Virology, January 2011, ASM Journals

    Professor Bin He

  28. The VP35 protein of Ebola virus impairs dendritic cell maturation induced by virus and lipopolysaccharide

    Article • Journal of General Virology, October 2009, Society for General Microbiology

    Professor Bin He

  29. Dephosphorylation of eIF2α Mediated by the γ134.5 Protein of Herpes Simplex Virus 1 Facilitates Viral Neuroinvasion

    Article • Journal of Virology, September 2009, ASM Journals

    Professor Bin He

  30. The γ134.5 Protein of Herpes Simplex Virus 1 Is Required To Interfere with Dendritic Cell Maturation during Productive Infection

    Article • Journal of Virology, March 2009, ASM Journals

    Professor Bin He

  31. Control of TANK-binding Kinase 1-mediated Signaling by the γ134.5 Protein of Herpes Simplex Virus 1

    Article • Journal of Biological Chemistry, January 2009, Elsevier

    Professor Bin He

  32. Antisense RNA directed to the human papillomavirus type 16 E7 mRNA from herpes simplex virus type 1 derived vectors is expressed in CaSki cells and downregulates E7 mRNA

    Article • Virology Journal, January 2007, Springer Science + Business Media

    Dr. Veijo I Hukkanen, Professor Bin He

  33. The VP35 Protein of Ebola Virus Inhibits the Antiviral Effect Mediated by Double-Stranded RNA-Dependent Protein Kinase PKR

    Article • Journal of Virology, October 2006, ASM Journals

    Professor Bin He

  34. Viruses, endoplasmic reticulum stress, and interferon responses

    Article • Cell Death and Differentiation, January 2006, Springer Science + Business Media

    Professor Bin He

  35. Characterization of the triplet repeats in the central domain of the γ 134·5 protein of herpes simplex virus 1

    Article • Journal of General Virology, September 2005, Society for General Microbiology

    Professor Bin He

  36. Increased efficacy of an interleukin-12-secreting herpes simplex virus in a syngeneic intracranial murine glioma model

    Article • Neuro-Oncology, July 2005, Oxford University Press (OUP)

    Professor Bin He

  37. Herpes Simplex Virus 1 Infection Activates the Endoplasmic Reticulum Resident Kinase PERK and Mediates eIF-2α Dephosphorylation by the γ134.5 Protein

    Article • Journal of Virology, February 2005, ASM Journals

    Professor Bin He

  38. Replication of Herpes Simplex Virus 1 Depends on the γ134.5 Functions That Facilitate Virus Response to Interferon and Egress in the Different Stages of Productive Infection

    Article • Journal of Virology, July 2004, ASM Journals

    Professor Bin He

  39. GADD34–PP1c recruited by Smad7 dephosphorylates TGFβ type I receptor

    Article • The Journal of Cell Biology, January 2004, Rockefeller University Press

    Professor Bin He

  40. Dephosphorylation of eIF-2α Mediated by the γ134.5 Protein of Herpes Simplex Virus Type 1 Is Required for Viral Response to Interferon but Is Not Sufficient for Efficient Viral Replication

    Article • Journal of Virology, September 2003, ASM Journals

    Professor Bin He

  41. Amino acid substitutions in the effector domain of the γ134.5 protein of herpes simplex virus 1 have differential effects on viral response to interferon-α

    Article • Virology, March 2003, Elsevier

    Professor Bin He

  42. Signals That Dictate Nuclear, Nucleolar, and Cytoplasmic Shuttling of the γ134.5 Protein of Herpes Simplex Virus Type 1

    Article • Journal of Virology, September 2002, ASM Journals

    Professor Bin He

  43. Val193 and Phe195 of the γ134.5 Protein of Herpes Simplex Virus 1 Are Required for Viral Resistance to Interferon-α/β

    Article • Virology, November 2001, Elsevier

    Professor Bin He

  44. Expression of interleukin-4 but not of interleukin-10 from a replicative herpes simplex virus type 1 viral vector precludes experimental allergic encephalomyelitis

    Article • Gene Therapy, May 2001, Springer Science + Business Media

    Professor Bin He

  45. AlaArg Motif in the Carboxyl Terminus of the γ134.5 Protein of Herpes Simplex Virus Type 1 Is Required for the Formation of a High-Molecular-Weight Complex That Dephosphorylates eIF-2α

    Article • Journal of Virology, April 2001, ASM Journals

    Professor Bin He

  46. The C-terminal domain of the regulatory protein NOVH is sufficient to promote interaction with fibulin 1C: A clue for a role of NOVH in cell-adhesion signaling

    Article • Proceedings of the National Academy of Sciences, February 1999, Proceedings of the National Academy of Sciences

    Professor Bin He

  47. The γ134.5 Protein of Herpes Simplex Virus 1 Has the Structural and Functional Attributes of a Protein Phosphatase 1 Regulatory Subunit and Is Present in a High Molecular Weight Complex with the Enzyme in Infected Cells

    Article • Journal of Biological Chemistry, August 1998, Elsevier

    Professor Bin He

  48. Treatment of intracranial gliomas in immunocompetent mice using herpes simplex viruses that express murine interleukins

    Article • Gene Therapy, January 1998, Springer Science + Business Media

    Professor Bin He

  49. Suppression of the phenotype of gamma(1)34.5- herpes simplex virus 1: failure of activated RNA-dependent protein kinase to shut off protein synthesis is associated with a deletion in the domain of the alpha47 gene

    Article • Journal of Virology, August 1997, ASM Journals

    Professor Bin He

  50. The γ 1 34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1α to dephosphorylate the α subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis b...

    Article • Proceedings of the National Academy of Sciences, February 1997, Proceedings of the National Academy of Sciences

    Professor Bin He

  51. The application of genetically engineered herpes simplex viruses to the treatment of experimental brain tumors.

    Article • Proceedings of the National Academy of Sciences, October 1996, Proceedings of the National Academy of Sciences

    Professor Bin He

  52. The carboxyl terminus of the murine MyD116 gene substitutes for the corresponding domain of the gamma(1)34.5 gene of herpes simplex virus to preclude the premature shutoff of total protein synthesis in infected human cells

    Article • Journal of Virology, January 1996, ASM Journals

    Professor Bin He