All Stories

  1. Unprecedented binding of Thioflavin T with well-ordered spherical aggregates: A false positive?
  2. A New Green Oxyma-Sulfonate Coupling Reagent for Sustainable Organic Transformations
  3. Morphology Transition of Tripeptides from Porous Spherical to Rod-like Nanostructures for Small-Molecule Adsorption
  4. Peptide-Based Strategies: Combating Alzheimer’s Amyloid β Aggregation through Ergonomic Design and Fibril Disruption
  5. Influence of Chirality on the Self-Assembly of Dipeptides and Sensing of Fe3+
  6. Early events during the aggregation of Aβ16-22-derived switch-peptides tracked using Protein Charge Transfer Spectra
  7. A smart adaptable metal sequestering peptide conjugate to modulate Aβ fibrillar aggregation
  8. Carbon‐Sulfur Bond Formation via Ipso Nucleophilic Substitution of Electron‐Deficient Benzenesulfonic Acid with Thiol
  9. Atomic Insight on Inhibition of Fibrillization of Dipeptides by Replacement of Phenylalanine with Tryptophan
  10. Unprecedented C–C Bond Formation via Ipso Nucleophilic Substitution of 2,4-Dinitrobenzene Sulfonic Acid with Active Methylene Compounds
  11. Chapter 19. Targeted Protein Degradation as a Therapeutic Avenue for Alzheimer's Disease
  12. A proteolytic functional amyloid digests pathogenic amyloids
  13. Copper chelating cyclic peptidomimetic inhibits Aβ fibrillogenesis
  14. Supramolecular helical self-assembly of small peptides
  15. Versatility in self-assembly and morphology of non-coded anthranilic acid and phenylglycine based dipeptide stereoisomers
  16. One‐Pot Synthesis of Amide, Dipeptide, Ester and Hydroxamate Using Oxyma and Thionyl Chloride (SOCl 2 )
  17. Protecting Group-Directed Diversity in the Morphology of Self-Assembled Ant-Aib Dipeptides: Garland-Like Architecture and Nanovesicle Formation
  18. Ethyl‐2‐Cyano‐2‐(2‐Nitrophenylsulfonyloximino)Acetate (ortho‐NosylOXY) Mediated One‐Pot Racemization Free Synthesis of Ureas, Carbamates, and Thiocarbamates via Curtius Rearrangement
  19. Crystal structure and supramolecular arrangement of heterochiral tripeptides
  20. An explicitly designed paratope of amyloid-β prevents neuronal apoptosis in vitro and hippocampal damage in rat brain
  21. Crystal structure of 1-(2,4,6-trichlorobenzoyloxy) benzotriazole (TCB-OBt): observation of uncommon intermolecular oxygen–oxygen interaction and synthetic application in amidation
  22. Site-specific single point mutation by anthranilic acid in hIAPP8–37 enhances anti-amyloidogenic activity
  23. Ethyl 2‐Cyano‐2‐(2‐nitrobenzenesulfonyloxyimino) Acetate ( ortho ‐NosylOXY)‐Mediated Double Beckmann Rearrangement of Ketoximes under Microwave Irradiation: A Mechanistic Perception
  24. Role of side-chain and chirality of the amino acids on the supramolecular assemblies of dipeptides
  25. Ethyl‐2‐cyano‐2‐(2‐nitrophenylsulfonyloximino)acetate ( ortho ‐ NosylOXY) Mediated Acetalization and Thioacetalization of Aldehydes
  26. Nanostructures from protected L/L and D/L amino acid containing dipeptides
  27. FeCl 3 ‐Mediated Boc Deprotection: Mild Facile Boc‐Chemistry in Solution and on Resin
  28. Peptidomimetics prepared by tail-to-side chain one component peptide stapling inhibit Alzheimer's amyloid-β fibrillogenesis
  29. Total degradation of extracellular amyloids by miniature artificial proteases
  30. A Synthetic Pro-Drug Peptide Reverses Amyloid-β-Induced Toxicity in the Rat Model of Alzheimer’s Disease
  31. Sequence specificity of amylin-insulin interaction: a fragment-based insulin fibrillation inhibition study
  32. Synthesis of o-Nitroarylamines via Ipso Nucleophilic Substitution of Sulfonic Acids
  33. Engineered peptidic constructs metabolize amyloid β by self-assembly-driven reactions
  34. Formation of supramolecular single and double helix-like structures from designed tripeptides
  35. Unique crystallographic signatures of Boc-Gly-Phe-Phe-OMe and Boc-Gly-Phg-Phe-OMe and their self-association
  36. (E)-Ethyl-2-cyano-2-(((2,4,6-trichlorobenzoyl)oxy)imino)acetate: A Modified Yamaguchi Reagent for Enantioselective Esterification, Thioesterification, Amidation, and Peptide Synthesis
  37. Synthesis of β -Amino Alcohols Using Ethyl 2-Cyano-2-(2-nitrobenzenesulfonyloxyimino)acetate (o -NosylOXY)
  38. Boc-Val-Val-OMe (Aβ39–40) and Boc-Ile-Ala-OMe (Aβ41–42) crystallize in a parallel β-sheet arrangement but generate a different morphology
  39. A Peptide Based Pro-Drug Ameliorates Amyloid-β Induced Neuronal Apoptosis in In Vitro SH-SY5Y Cells
  40. FeCl3-Mediated Side Chain Modification of Aspartic Acid- and Glutamic Acid-Containing Peptides on a Solid Support
  41. Direct Synthesis of Sulphonates of Alcohol, Oxyma-O -sulphonates and Oxime-O -sulphonates under Microwave Irradiation
  42. A Peptide Based Pro-drug Disrupts Alzheimer’s Amyloid into Non-toxic Species and Reduces Aβ Induced Toxicity In Vitro
  43. Disaggregation of Amylin Aggregate by Novel Conformationally Restricted Aminobenzoic Acid containing α/β and α/γ Hybrid Peptidomimetics
  44. Near UV-Visible electronic absorption originating from charged amino acids in a monomeric protein
  45. Protective effects of β-sheet breaker α/β-hybrid peptide against amyloid β-induced neuronal apoptosis in vitro
  46. Ethyl 2-(tert-Butoxycarbonyloxyimino)-2-cyanoacetate (Boc-Oxyma): An Efficient Reagent for the Racemization Free Synthesis of Ureas, Carbamates and Thiocarbamates via Lossen Rearrangement
  47. ChemInform Abstract: Benzoxazole and Benzothiazole Synthesis from Carboxylic Acids in Solution and on Resin by Using Ethyl 2-Cyano-2-(2-nitrobenzenesulfonyloxyimino)acetate and para-Toluenesulfonic Acid.
  48. Functional Characterization of the Odorant Receptor 51E2 in Human Melanocytes
  49. Benzoxazole and Benzothiazole Synthesis from Carboxylic Acids in Solution and on Resin by Using Ethyl 2-Cyano-2-(2-nitrobenzenesulfonyloxyimino)acetate and para -Toluenesulfonic Acid
  50. ChemInform Abstract: Racemization Free Longer N-Terminal Peptide Hydroxamate Synthesis on Solid Support Using Ethyl 2-(tert-Butoxycarbonyloxyimino)-2-cyanoacetate.
  51. Investigation of Novel Spectroscopic Features in the Near Ultraviolet Region Arising from Non-Aromatic Amino Acids in Peptides and Proteins
  52. Amyloid β derived switch-peptides as a tool for investigation of early events of aggregation: a combined experimental and theoretical approach
  53. The role of caffeine as an inhibitor in the aggregation of amyloid forming peptides: a unified molecular dynamics simulation and experimental study
  54. Racemization free longer N-terminal peptide hydroxamate synthesis on solid support using ethyl 2-(tert-butoxycarbonyloxyimino)-2-cyanoacetate
  55. Dynamic Combinatorial Enrichment of PolyconformationalD-/L-Peptide Dimers
  56. Inhibition of Alzheimer's amyloid-β peptide aggregation and its disruption by a conformationally restricted α/β hybrid peptide
  57. ChemInform Abstract: Ethyl 2-Cyano-2-(2-nitrobenzenesulfonyloxyimino)acetate (o-NosylOXY): A Recyclable Coupling Reagent for Racemization-Free Synthesis of Peptide, Amide, Hydroxamate, and Ester.
  58. ChemInform Abstract: Synthesis of O-Benzyl Hydroxamates Employing the Sulfonate Esters of N-Hydroxybenzotriazole.
  59. Microwave assisted chemoselective organocatalytic peptide alcohol synthesis from C-terminal amide
  60. ChemInform Abstract: Ethyl 2-Cyano-2-(4-nitrophenylsulfonyloxyimino)acetate-Mediated Lossen Rearrangement: Single-Pot Racemization-Free Synthesis of Hydroxamic Acids and Ureas from Carboxylic Acids.
  61. Ethyl 2-Cyano-2-(2-nitrobenzenesulfonyloxyimino)acetate (o-NosylOXY): A Recyclable Coupling Reagent for Racemization-Free Synthesis of Peptide, Amide, Hydroxamate, and Ester
  62. Reversal of Aggregation Using β-Breaker Dipeptide Containing Peptides: Application to Aβ(1–40)Self-Assembly and Its Inhibition
  63. Ethyl 2-Cyano-2-(4-nitrophenylsulfonyloxyimino)acetate-Mediated Lossen Rearrangement: Single-Pot Racemization-Free Synthesis of Hydroxamic Acids and Ureas from Carboxylic Acids
  64. Synthesis of O-benzyl hydroxamates employing the sulfonate esters of N-hydroxybenzotriazole
  65. Phenolic Ester Mediated Oligopeptide Synthesis Promoted by HOBt
  66. ChemInform Abstract: An Unexpected Involvement of Ethyl-2-cyano-2-(hydroxyimino)acetate Cleaved Product in the Promotion of the Synthesis of Nitriles from Aldoximes: A Mechanistic Perception.
  67. ChemInform Abstract: Sulfonamide Synthesis via Oxyma-O-sulfonates - Compatibility to Acid Sensitive Groups and Solid-Phase Peptide Synthesis.
  68. An unexpected involvement of ethyl-2-cyano-2-(hydroxyimino) acetate cleaved product in the promotion of the synthesis of nitriles from aldoximes: a mechanistic perception
  69. Modulation of Aggregation Propensity of Aβ38 by Site Specific Multiple Proline Substitution
  70. ChemInform Abstract: Ethyl 2-(tert-Butoxycarbonyloxyimino)-2-cyanoacetate (Boc-Oxyma) as Coupling Reagent for Racemization-Free Esterification, Thioesterification, Amidation and Peptide Synthesis.
  71. Sulfonamide Synthesis via Oxyma-O-sulfonates - Compatibility to Acid Sensitive Groups and Solid-Phase Peptide Synthesis
  72. Ethyl 2-(tert-Butoxycarbonyloxyimino)-2-cyanoacetate (Boc-Oxyma) as Coupling Reagent for Racemization-Free Esterification, Thioesterification, Amidation and Peptide Synthesis
  73. Waste reduction in amide synthesis by a continuous method based on recycling of the reaction mixture
  74. Sulfonamide synthesis using N-hydroxybenzotriazole sulfonate: an alternative to pentafluorophenyl (PFP) and trichlorophenyl (TCP) esters of sulfonic acids
  75. Catalyst and solvent-free amidation of inactive esters of N-protected amino acids
  76. ChemInform Abstract: Selective para-Metalation of Unprotected 3-Methoxy and 3,5-Dimethoxy Benzoic Acids with n-Butyl Lithium-Potassium tert-Butoxide (LIC-KOR): Synthesis of 3,5-Dimethoxy-4-methyl Benzoic Acid.
  77. Switch-Peptides: Design and Characterization of Controllable Super-Amyloid-Forming Host-Guest Peptides as Tools for Identifying Anti-Amyloid Agents
  78. Switch-Peptides: From Conformational Studies to Alzheimer's Disease
  79. Switch on Amyloid β Peptide Self-Assembly by Enzyme-Triggered Acyl Migration
  80. Switch-Peptides:  Controlling Self-Assembly of Amyloid β-Derived Peptides in vitro by Consecutive Triggering of Acyl Migrations
  81. Switch Peptides In Statu Nascendi: Induction of Conformational Transitions Relevant to Degenerative Diseases
  82. Switch-Peptide in statu nascendi: Induktion von Konformationsübergängen und deren Bedeutung in degenerativen Erkrankungen
  83. ChemInform Abstract: Synthesis of Ethyl Arylacetates by Means of Friedel-Crafts Reactions of Aromatic Compounds with Ethyl α-Chloro-α-(ethylthio)acetate Catalyzed by Ytterbium Triflate.
  84. Synthesis of ethyl arylacetates by means of Friedel–Crafts reactions of aromatic compounds with ethyl α-chloro-α-(ethylthio)acetate catalysed by ytterbium triflate
  85. Selective para metalation of unprotected 3-methoxy and 3,5-dimethoxy benzoic acids with n-butyl lithium–potassium tert-butoxide (LIC–KOR): synthesis of 3,5-dimethoxy-4-methyl benzoic acid