All Stories

  1. Foreword
  2. Direct and Indirect Effects on Viral Translation and RNA Replication Are Required for AUF1 Restriction of Enterovirus Infections in Human Cells
  3. Exploitation of nuclear functions by human rhinovirus, a cytoplasmic RNA virus
  4. Replication of the Poliovirus Genome
  5. Hijacking Host Functions for Translation and RNA Replication by Enteroviruses
  6. Functional Consequences of RNA 5′-Terminal Deletions on Coxsackievirus B3 RNA Replication and Ribonucleoprotein Complex Formation
  7. Mammalian Polycistronic mRNAs and Disease
  8. Diverse Strategies Used by Picornaviruses to Escape Host RNA Decay Pathways
  9. Construction of a subgenomic CV-B3 replicon expressing emerald green fluorescent protein to assess viral replication of a cardiotropic enterovirus strain in cultured human cells
  10. Generation of Recombinant Polioviruses Harboring RNA Affinity Tags in the 5′ and 3′ Noncoding Regions of Genomic RNAs
  11. Foreword
  12. Divergent Requirement for a DNA Repair Enzyme during Enterovirus Infections
  13. Viral Determinants of miR-122-Independent Hepatitis C Virus Replication
  14. Picornaviruses and nuclear functions: targeting a cellular compartment distinct from the replication site of a positive-strand RNA virus
  15. A 21st Century Perspective of Poliovirus Replication
  16. Picornaviruses: Pathogenesis and Molecular Biology
  17. Transformation
  18. Evolutionary and Population Biology of Streptococcus Pneumoniae
  19. Genome Replication II: the Process
  20. Genome Replication I: the Players
  21. Processing Determinants and Functions of Cleavage Products of Picornavirus Polyproteins
  22. Differential restriction patterns of mRNA decay factor AUF1 during picornavirus infections
  23. Translation and Host Cell Shutoff
  24. In Memoriam John J. Holland (1929-2013): a Pioneer in Molecular Virology
  25. Revelations from a bicistronic calcium channel gene
  26. Differential cleavage of IRES trans-acting factors (ITAFs) in cells infected by human rhinovirus
  27. Inhibition of Poliovirus-Induced Cleavage of Cellular Protein PCBP2 Reduces the Levels of Viral RNA Replication
  28. Poliovirus infection induces the co-localization of cellular protein SRp20 with TIA-1, a cytoplasmic stress granule protein
  29. Cellular mRNA Decay Protein AUF1 Negatively Regulates Enterovirus and Human Rhinovirus Infections
  30. Methods to study RNA virus molecular biology
  31. Viral Proteinase Requirements for the Nucleocytoplasmic Relocalization of Cellular Splicing Factor SRp20 during Picornavirus Infections
  32. MDA5 Detects the Double-Stranded RNA Replicative Form in Picornavirus-Infected Cells
  33. Viral subversion of host functions for picornavirus translation and RNA replication
  34. SARS Coronavirus nsp1 Protein Induces Template-Dependent Endonucleolytic Cleavage of mRNAs: Viral mRNAs Are Resistant to nsp1-Induced RNA Cleavage
  35. Re-localization of Cellular Protein SRp20 during Poliovirus Infection: Bridging a Viral IRES to the Host Cell Translation Apparatus
  36. Engineered Picornavirus VPg-RNA Substrates: Analysis of a Tyrosyl-RNA Phosphodiesterase Activity
  37. Mechanistic Intersections Between Picornavirus Translation and RNA Replication
  38. Alphacoronavirus Transmissible Gastroenteritis Virus nsp1 Protein Suppresses Protein Translation in Mammalian Cells and in Cell-Free HeLa Cell Extracts but Not in Rabbit Reticulocyte Lysate
  39. Stress-Inducible Alternative Translation Initiation of Human Cytomegalovirus Latency Protein pUL138
  40. Delayed kinetics of poliovirus RNA synthesis in a human cell line with reduced levels of hnRNP C proteins
  41. Positive-Strand RNA Virus Replication in Vertebrate Hosts
  42. Mechanistic Consequences of hnRNP C Binding to Both RNA Termini of Poliovirus Negative-Strand RNA Intermediates
  43. Bridging IRES elements in mRNAs to the eukaryotic translation apparatus
  44. Altered interactions between stem-loop IV within the 5′ noncoding region of coxsackievirus RNA and poly(rC) binding protein 2: Effects on IRES-mediated translation and viral infectivity
  45. The linker domain of poly(rC) binding protein 2 is a major determinant in poliovirus cap-independent translation
  46. IRES-mediated pathways to polysomes: nuclear versus cytoplasmic routes
  47. Alternative polyadenylation signals in the 3′ non-coding region of a voltage-gated potassium channel gene are major determinants of mRNA isoform expression
  48. Picornaviruses: Molecular Biology
  49. Cellular Protein Modification by Poliovirus: the Two Faces of Poly(rC)-Binding Protein
  50. A nucleo-cytoplasmic SR protein functions in viral IRES-mediated translation initiation
  51. Gene Expression and Replication of Picornaviruses
  52. An Authentic 3′ Noncoding Region Is Necessary for Efficient Poliovirus Replication
  53. Resistance is futile
  54. Allosteric Effects of Ligands and Mutations on Poliovirus RNA-Dependent RNA Polymerase
  55. Functional Interaction of Heterogeneous Nuclear Ribonucleoprotein C with Poliovirus RNA Synthesis Initiation Complexes
  56. Atomic Force Microscopy Analysis of Icosahedral Virus RNA
  57. Differential Rescue of Poliovirus RNA Replication Functions by Genetically Modified RNA Polymerase Precursors
  58. Multimerization of poly(rC) binding protein 2 is required for translation initiation mediated by a viral IRES
  59. Poliovirus proves IRES-istible in vivo
  60. Regulation of picornavirus gene expression
  61. Strand-Specific RNA Synthesis Determinants in the RNA-Dependent RNA Polymerase of Poliovirus
  62. Cell-Dependent Role for the Poliovirus 3′ Noncoding Region in Positive-Strand RNA Synthesis
  63. Functional conservation of the hydrophobic domain of polypeptide 3AB between human rhinovirus and poliovirus
  64. Distinct Poly(rC) Binding Protein KH Domain Determinants for Poliovirus Translation Initiation and Viral RNA Replication
  65. Molecular Biology of Picornavirus
  66. Subdomain Specific Functions of the RNA Polymerase Region of Poliovirus 3CD Polypeptide
  67. Requirements for Assembly of Poliovirus Replication Complexes and Negative-Strand RNA Synthesis
  68. A Group B Coxsackievirus/Poliovirus 5′ Nontranslated Region Chimera Can Act as an Attenuated Vaccine Strain in Mice
  69. Differential utilization of poly(rC) binding protein 2 in translation directed by picornavirus IRES elements
  70. Pyrimidine-Rich Region Mutations Compensate for a Stem-Loop V Lesion in the 5′ Noncoding Region of Poliovirus Genomic RNA
  71. Modulation of the RNA Binding and Protein Processing Activities of Poliovirus Polypeptide 3CD by the Viral RNA Polymerase Domain
  72. RNA structure adjacent to the attenuation determinant in the 5'-non-coding region influences poliovirus viability
  73. Translation and Replication Properties of the Human Rhinovirus Genomein Vivoandin Vitro
  74. RNA Determinants of Picornavirus Cap-Independent Translation Initiation
  75. Determinants of Membrane Association for Poliovirus Protein 3AB
  76. Poly(rC) binding protein 2 binds to stem-loop IV of the poliovirus RNA 5' noncoding region: identification by automated liquid chromatography-tandem mass spectrometry.
  77. Mutations in the Poliovirus 3CD Proteinase S1-Specificity Pocket Affect Substrate Recognition and RNA Binding
  78. Stem-Loop Structure Synergy in Binding Cellular Proteins to the 5′| Noncoding Region of Poliovirus RNA
  79. Expression of virus-encoded proteinases: functional and structural similarities with cellular enzymes
  80. 3CD Cleavage of the Poliovirus P1 Precursor: A Model for Complex Proteinase/Substrate Interactions
  81. Alternate poliovirus nonstructural protein processing cascades generated by primary sites of 3C proteinase cleavage
  82. High frequency of single-base transitions and extreme frequency of precise multiple-base reversion mutations in poliovirus.
  83. Self-cleaving proteases
  84. Poliovirus translation initiation: Differential effects of directed and selected mutations in the 5′ noncoding region of viral RNAs
  85. A genetic locus in mutant poliovirus genomes involved in overproduction of RNA polymerase and 3C proteinase
  86. Polyprotein processing of Theiler's murine encephalomyelitis virus
  87. Protein 3CD is the major poliovirus proteinase responsible for cleavage of the p1 capsid precursor
  88. Defined recombinants of poliovirus and coxsackievirus: Sequence-specific deletions and functional substitutions in the 5′-noncoding regions of viral RNAs
  89. The Development of New Poliovirus Vaccines Based on Molecular Cloning
  90. Construction of a "mutagenesis cartridge" for poliovirus genome-linked viral protein: isolation and characterization of viable and nonviable mutants.
  91. The Molecular Biology of Poliovirus.Friedrich Koch , Gebhard Koch
  92. Expression of the poliovirus genome from infectious cDNA is dependent upon arrangements of eukaryotic and prokaryotic sequences in recombinant plasmids
  93. Site-specific mutagenesis of cDNA clones expressing a poliovirus proteinase
  94. in vitromolecular genetics as a tool for determining the differential cleavage specificities of the polivirus 3C proteinase
  95. An Infectious cDNA clone of the poliovirus sabin strain could be used as a stable repository and inoculum for the oral polio live vaccine
  96. A chimeric plasmid from cDNA clones of poliovirus and coxsackievirus produces a recombinant virus that is temperature-sensitive.
  97. Organization of the poliovirus genome and the sites for proteolytic processing
  98. Expression of a cloned gene segment of poliovirus in E. coli: Evidence for autocatalytic production of the viral proteinase
  99. Structure, Proteolytic Processing, and Neutralization Antigenic Sites of Poliovirus
  100. Production of infectious poliovirus from cloned cDNA is dramatically increased by SV40 transcription and replication signals
  101. Membrane fractions active in poliovirus RNA replication contain VPg precursor polypeptides
  102. Poliovirus RNA synthesis in Vitro: Structuralelements and antibody inhibition
  103. Proteolytic processing of poliovirus polypeptides: antibodies to polypeptide P3-7c inhibit cleavage at glutamine-glycine pairs.
  104. A membrane-associated precursor to poliovirus VPg identified by immunoprecipitation with antibodies directed against a synthetic heptapeptide
  105. Cleavage sites in the polypeptide precursors of poliovirus protein P2-X
  106. Primary structure, gene organization and polypeptide expression of poliovirus RNA
  107. Poliovirus replication proteins: RNA sequence encoding P3-1b and the sites of proteolytic processing.
  108. Structure, Possible Function, and Biosynthesis of VPg, the Genome-linked Protein of Poliovirus
  109. Protein-linked RNA of poliovirus is competent to form an initiation complex of translation in vitro
  110. Virus protein changes and RNA termini alterations evolving during persistent infection
  111. Defective Interfering RNA Viruses and the Host-Cell Response
  113. Internal genome deletions in two distinct classes of defective interfering particles of vesicular stomatitis virus.
  114. Persistent vesicular stomatitis virus infection mediates base substitutions in viral RNA termini
  115. Evolution of multiple genome mutations during long-term persistent infection by vesicular stomatitis virus
  116. The nucleotide sequence of the 5′ terminus of vesicular stomatitis virus RNA
  117. Sequence of a RNA templated by the 3'-OH RNA terminus of defective interfering particles of vesicular stomatitis virus.
  119. Genome Replication I: the Players
  120. Genome Replication II: the Process
  121. Coxsackievirus B RNA Replication: Lessons from Poliovirus