All Stories

  1. CRISPR–Cas9 genome editing induces a p53-mediated DNA damage response

    Article • Nature Medicine, June 2018, Springer Science + Business Media

    Bernhard Schmierer

  2. CRISPR screening is improved by inclusion of unique molecular identifiers or UMI.

    Article • Molecular Systems Biology, October 2017, EMBO

    Bernhard Schmierer

  3. Structural insights into the DNA-binding specificity of E2F family transcription factors

    Article • Nature Communications, December 2015, Nature

    Bernhard Schmierer

  4. Response to comment on "Controlling long-term signaling: Receptor dynamics determine attenuation and refractory behavior of the TGF-  pathway"--Smad2/3 activity does not predict the dynamics of transcription

    Article • Science Signaling, September 2014, American Association for the Advancement of Science

    Bernhard Schmierer

  5. Controlling Long-Term Signaling: Receptor Dynamics Determine Attenuation and Refractory Behavior of the TGF-  Pathway

    Article • Science Signaling, December 2013, American Association for the Advancement of Science

    Bernhard Schmierer

  6. Transcription Factor Binding in Human Cells Occurs in Dense Clusters Formed around Cohesin Anchor Sites

    Article • Cell, August 2013, Elsevier

    Bernhard Schmierer

  7. Dynamical Scenarios for Chromosome Bi-orientation

    Article • Biophysical Journal, June 2013, Elsevier

    Bernhard Schmierer

  8. Cell cycle commitment in budding yeast emerges from the cooperation of multiple bistable switches

    Article • Open Biology, November 2011, Royal Society Publishing

    Bernhard Schmierer

  9. Studying Smad2 intranuclear diffusion dynamics by mathematical modelling of FRAP experiments

    Article • Integrative Biology, January 2011, Oxford University Press (OUP)

    Bernhard Schmierer

  10. Asparagine and Aspartate Hydroxylation of the Cytoskeletal Ankyrin Family Is Catalyzed by Factor-inhibiting Hypoxia-inducible Factor

    Article • Journal of Biological Chemistry, December 2010, American Society for Biochemistry & Molecular Biology (ASBMB)

    Bernhard Schmierer

  11. Hypoxia-dependent sequestration of an oxygen sensor by a widespread structural motif can shape the hypoxic response - a predictive kinetic model

    Article • BMC Systems Biology, January 2010, Springer Science + Business Media

    Bernhard Schmierer

  12. Two highly related regulatory subunits of PP2A exert opposite effects on TGF- /Activin/Nodal signalling

    Article • Development, September 2008, The Company of Biologists

    Bernhard Schmierer

  13. Mathematical modeling identifies Smad nucleocytoplasmic shuttling as a dynamic signal-interpreting system

    Article • Proceedings of the National Academy of Sciences, May 2008, Proceedings of the National Academy of Sciences

    Bernhard Schmierer

  14. TGFβ–SMAD signal transduction: molecular specificity and functional flexibility

    Article • Nature Reviews Molecular Cell Biology, December 2007, Nature

    Bernhard Schmierer

  15. Upregulation of chicken p15INK4b at senescence and in the developing brain

    Article • Journal of Cell Science, June 2006, The Company of Biologists

    Bernhard Schmierer

  16. Kinetic Analysis of Smad Nucleocytoplasmic Shuttling Reveals a Mechanism for Transforming Growth Factor β-Dependent Nuclear Accumulation of Smads

    Article • Molecular and Cellular Biology, November 2005, ASM Journals

    Bernhard Schmierer

  17. Analysis of Smad nucleocytoplasmic shuttling in living cells

    Article • Journal of Cell Science, August 2004, The Company of Biologists

    Bernhard Schmierer

  18. Activin A and Follicle-Stimulating Hormone Control Tight Junctions in Avian Granulosa Cells by Regulating Occludin Expression1

    Article • Biology of Reproduction, May 2004, Oxford University Press (OUP)

    Bernhard Schmierer

  19. Activin A Signaling Induces Smad2, but Not Smad3, Requiring Protein Kinase A Activity in Granulosa Cells from the Avian Ovary

    Article • Journal of Biological Chemistry, March 2003, American Society for Biochemistry & Molecular Biology (ASBMB)

    Bernhard Schmierer

  20. Activin and Follicle-Stimulating Hormone Signaling Are Required for Long-Term Culture of Functionally Differentiated Primary Granulosa Cells from the Chicken Ovary1

    Article • Biology of Reproduction, February 2003, Oxford University Press (OUP)

    Bernhard Schmierer

  21. Endothelial Cells Downregulate Expression of the 70 kDa Heat Shock Protein during Hypoxia

    Article • Biochemical and Biophysical Research Communications, August 2000, Elsevier

    Bernhard Schmierer