All Stories

  1. CRISPR–Cas9 genome editing induces a p53-mediated DNA damage response
  2. CRISPR screening is improved by inclusion of unique molecular identifiers or UMI.
  3. Structural insights into the DNA-binding specificity of E2F family transcription factors
  4. Response to comment on "Controlling long-term signaling: Receptor dynamics determine attenuation and refractory behavior of the TGF-  pathway"--Smad2/3 activity does not predict the dynamics of transcription
  5. Controlling Long-Term Signaling: Receptor Dynamics Determine Attenuation and Refractory Behavior of the TGF-  Pathway
  6. Transcription Factor Binding in Human Cells Occurs in Dense Clusters Formed around Cohesin Anchor Sites
  7. Dynamical Scenarios for Chromosome Bi-orientation
  8. Cell cycle commitment in budding yeast emerges from the cooperation of multiple bistable switches
  9. Studying Smad2 intranuclear diffusion dynamics by mathematical modelling of FRAP experiments
  10. Asparagine and Aspartate Hydroxylation of the Cytoskeletal Ankyrin Family Is Catalyzed by Factor-inhibiting Hypoxia-inducible Factor
  11. Hypoxia-dependent sequestration of an oxygen sensor by a widespread structural motif can shape the hypoxic response - a predictive kinetic model
  12. Two highly related regulatory subunits of PP2A exert opposite effects on TGF- /Activin/Nodal signalling
  13. Mathematical modeling identifies Smad nucleocytoplasmic shuttling as a dynamic signal-interpreting system
  14. TGFβ–SMAD signal transduction: molecular specificity and functional flexibility
  15. Upregulation of chicken p15INK4b at senescence and in the developing brain
  16. Kinetic Analysis of Smad Nucleocytoplasmic Shuttling Reveals a Mechanism for Transforming Growth Factor β-Dependent Nuclear Accumulation of Smads
  17. Analysis of Smad nucleocytoplasmic shuttling in living cells
  18. Activin A and Follicle-Stimulating Hormone Control Tight Junctions in Avian Granulosa Cells by Regulating Occludin Expression1
  19. Activin A Signaling Induces Smad2, but Not Smad3, Requiring Protein Kinase A Activity in Granulosa Cells from the Avian Ovary
  20. Activin and Follicle-Stimulating Hormone Signaling Are Required for Long-Term Culture of Functionally Differentiated Primary Granulosa Cells from the Chicken Ovary1
  21. Endothelial Cells Downregulate Expression of the 70 kDa Heat Shock Protein during Hypoxia