All Stories

  1. The progressive spectral signal-to-noise ratio of cryo-electron micrograph movies as a tool to assess quality and radiation damage

    Article • Computer Methods and Programs in Biomedicine, June 2022, Elsevier

    Bernard Heymann

  2. Cryo-Electron Tomography of the Herpesvirus Procapsid Reveals Interactions of the Portal with the Scaffold and a Shift on Maturation

    Article • mBio, April 2021, ASM Journals

    Bernard Heymann

  3. FSC-Q: a CryoEM map-to-atomic model quality validation based on the local Fourier shell correlation

    Article • Nature Communications, January 2021, Springer Science + Business Media

    Bernard Heymann

  4. Cryo-electron tomography of the herpesvirus procapsid reveals interactions of the portal with the scaffold and a shift on maturation

    Article • October 2020, Cold Spring Harbor Laboratory Press

    Bernard Heymann

  5. High resolution electron tomography and segmentation‐by‐modeling interpretation in Bsoft

    Article • Protein Science, September 2020, Wiley

    Bernard Heymann

  6. The Mottled Capsid of the Salmonella Giant Phage SPN3US, a Likely Maturation Intermediate with a Novel Internal Shell

    Article • Viruses, August 2020, MDPI AG

    Bernard Heymann

  7. FSC-Q: A CryoEM map-to-atomic model quality validation based on the local Fourier Shell Correlation

    Article • May 2020, Cold Spring Harbor Laboratory Press

    Bernard Heymann

  8. Protocols for Processing and Interpreting cryoEM Data Using Bsoft: A Case Study of the Retinal Adhesion Protein, Retinoschisin

    Article • BIO-PROTOCOL, January 2020, Bio-Protocol, LLC

    Bernard Heymann

  9. Atomic structures of an entire contractile injection system in both the extended and contracted states

    Article • Nature Microbiology, August 2019, Springer Science + Business Media

    Bernard Heymann

  10. Hunting for the Adhesion Molecule, Retinoschisin, in Retina using CEMOVIS

    Article • Microscopy and Microanalysis, August 2019, Oxford University Press (OUP)

    Bernard Heymann

  11. Localization of the Herpesvirus Portal

    Article • Microscopy and Microanalysis, August 2019, Oxford University Press (OUP)

    Bernard Heymann

  12. Carbon replicas reveal double stranded structure of tight junctions in phase-contrast electron microscopy

    Article • Communications Biology, March 2019, Springer Science + Business Media

    Bernard Heymann

  13. Cryo-EM of retinoschisin branched networks suggests an intercellular adhesive scaffold in the retina

    Article • The Journal of Cell Biology, January 2019, Rockefeller University Press

    Bernard Heymann

  14. Single-particle reconstruction statistics: a diagnostic tool in solving biomolecular structures by cryo-EM

    Article • Acta Crystallographica Section F Structural Biology Communications, January 2019, International Union of Crystallography

    Bernard Heymann

  15. Map Challenge assessment: Fair comparison of single particle cryoEM reconstructions

    Article • Journal of Structural Biology, November 2018, Elsevier

    Bernard Heymann

  16. The first single particle analysis Map Challenge: A summary of the assessments

    Article • Journal of Structural Biology, November 2018, Elsevier

    Bernard Heymann

  17. Single particle reconstruction and validation using Bsoft for the map challenge

    Article • Journal of Structural Biology, October 2018, Elsevier

    Bernard Heymann

  18. Using Reconstruction Statistics to Predict the Number of Images Required for Single Particle Analysis

    Article • Microscopy and Microanalysis, August 2018, Oxford University Press (OUP)

    Bernard Heymann

  19. Tomographic Reconstruction from Electron Micrographs

    Article • December 2017, Springer Science + Business Media

    Bernard Heymann

  20. Guidelines for using Bsoft for high resolution reconstruction and validation of biomolecular structures from electron micrographs

    Article • Protein Science, October 2017, Wiley

    Bernard Heymann

  21. Galactose Induces Formation of Chains of the Retinal Adhesion Protein, Retinoschisin

    Article • Microscopy and Microanalysis, July 2017, Oxford University Press (OUP)

    Bernard Heymann

  22. Primary Envelopment of the Herpes Simplex 1 Virion

    Article • Microscopy and Microanalysis, July 2017, Oxford University Press (OUP)

    Bernard Heymann

  23. The Primary Enveloped Virion of Herpes Simplex Virus 1: Its Role in Nuclear Egress

    Article • mBio, June 2017, ASM Journals

    Bernard Heymann

  24. The Structure of HIV-1 Rev Filaments Suggests a Bilateral Model for Rev-RRE Assembly

    Article • Structure, July 2016, Elsevier

    Bernard Heymann

  25. A Polymerase-Activating Host Factor, YajQ, Bound to the Bacteriophage ϕ6 Capsid

    Article • Microscopy and Microanalysis, July 2016, Oxford University Press (OUP)

    Bernard Heymann

  26. The Electron Microscopy eXchange (EMX) initiative

    Article • Journal of Structural Biology, May 2016, Elsevier

    Bernard Heymann

  27. Revealing the molecular mechanisms of a retinal genetic disease

    Article • Proceedings of the National Academy of Sciences, April 2016, Proceedings of the National Academy of Sciences

    Dr Gökhan Tolun, Bernard Heymann

  28. α-Synuclein Amyloid Fibrils with Two Entwined, Asymmetrically Associated Protofibrils

    Article • Journal of Biological Chemistry, January 2016, Elsevier

    Bernard Heymann

  29. Subassemblies and Asymmetry in Assembly of Herpes Simplex Virus Procapsid

    Article • mBio, October 2015, ASM Journals

    Bernard Heymann

  30. α-Synuclein Amyloid Fibrils Formed of Two Protofibrils

    Article • Microscopy and Microanalysis, August 2015, Oxford University Press (OUP)

    Bernard Heymann

  31. CTF Challenge: Result summary

    Article • Journal of Structural Biology, June 2015, Elsevier

    Bernard Heymann

  32. Validation of 3D EM Reconstructions: The Phantom in the Noise

    Article • AIMS Biophysics, January 2015, American Institute of Mathematical Sciences (AIMS)

    Bernard Heymann

  33. Phage Capsid-like Structure of Myxococcus xanthus Encapsulin, a Protein Shell That Stores Iron

    Article • Microscopy and Microanalysis, August 2014, Oxford University Press (OUP)

    Bernard Heymann

  34. The Phantom in the Noise and Validation of 3D EM Reconstructions

    Article • Microscopy and Microanalysis, August 2014, Oxford University Press (OUP)

    Bernard Heymann

  35. A virus capsid‐like nanocompartment that stores iron and protects bacteria from oxidative stress

    Article • The EMBO Journal, July 2014, EMBO

    Bernard Heymann

  36. One number does not fit all: Mapping local variations in resolution in cryo-EM reconstructions

    Article • Journal of Structural Biology, November 2013, Elsevier

    Bernard Heymann

  37. A Two-Pronged Structural Analysis of Retroviral Maturation Indicates that Core Formation Proceeds by a Disassembly-Reassembly Pathway Rather than a Displacive Transition

    Article • Journal of Virology, October 2013, ASM Journals

    Rebecca C Craven, Bernard Heymann

  38. Clathrin-coated vesicles from brain have small payloads: A cryo-electron tomographic study

    Article • Journal of Structural Biology, October 2013, Elsevier

    Bernard Heymann

  39. Nucleic Acid Content of HBV Capsids Depends on its CTD-Phosphorylation State

    Article • Microscopy and Microanalysis, August 2013, Oxford University Press (OUP)

    Bernard Heymann

  40. Subunit Folds and Maturation Pathway of a dsRNA Virus Capsid

    Article • Structure, August 2013, Elsevier

    Bernard Heymann

  41. α Synuclein Amyloid Fibrils With Two Entwined Protofibrils Each With One Subunit Per 4.7 Å Axial Rise

    Article • Microscopy and Microanalysis, August 2013, Oxford University Press (OUP)

    Bernard Heymann

  42. Three-dimensional Structure of the Toxin-delivery Particle Antifeeding Prophage of Serratia entomophila

    Article • Journal of Biological Chemistry, August 2013, Elsevier

    Bernard Heymann

  43. Data management challenges in three-dimensional EM

    Article • Nature Structural & Molecular Biology, December 2012, Springer Science + Business Media

    Sjors Scheres, Bernard Heymann

  44. Packaging Accessory Protein P7 and Polymerase P2 Have Mutually Occluding Binding Sites inside the Bacteriophage  6 Procapsid

    Article • Journal of Virology, August 2012, ASM Journals

    Bernard Heymann

  45. Cryo-electron tomographic characterization of structural changes in influenza virus at low pH

    Article • Microscopy and Microanalysis, July 2012, Oxford University Press (OUP)

    Bernard Heymann

  46. Towards an atlas of mammalian cell ultrastructure by cryo soft X-ray tomography

    Article • Journal of Structural Biology, February 2012, Elsevier

    Bernard Heymann

  47. Structural Changes in Influenza Virus at Low pH Characterized by Cryo-Electron Tomography

    Article • Journal of Virology, January 2012, ASM Journals

    Bernard Heymann

  48. Procapsid Assembly, Maturation, Nuclear Exit: Dynamic Steps in the Production of Infectious Herpesvirions

    Article • November 2011, Springer Science + Business Media

    Bernard Heymann

  49. Stepwise Expansion of the Bacteriophage ϕ6 Procapsid: Possible Packaging Intermediates

    Article • Journal of Molecular Biology, November 2011, Elsevier

    Bernard Heymann

  50. Cryo-Electron Microscopy and Tomography Reveal Stepwise Expansion of the Bacteriophage φ6 Procapsid

    Article • Microscopy and Microanalysis, July 2011, Oxford University Press (OUP)

    Bernard Heymann

  51. HIV-1 Maturation Inhibitor Bevirimat Stabilizes the Immature Gag Lattice

    Article • Journal of Virology, November 2010, ASM Journals

    Bernard Heymann

  52. Three-dimensional cellular ultrastructure resolved by X-ray microscopy

    Article • Nature Methods, November 2010, Springer Science + Business Media

    Bernard Heymann

  53. Three-dimensional Structures of Pleiomorphic Viruses from Cryo-Electron Tomography

    Article • November 2010, Royal Society of Chemistry

    Bernard Heymann

  54. Cryo-electron tomography of bacteriophage φ6 procapsids shows random occupancy of the binding sites for RNA polymerase and packaging NTPase

    Article • Journal of Structural Biology, September 2010, Elsevier

    Bernard Heymann

  55. Retrovirus Capsid Assembly and Polymorphism Studied by Cryo-EM and Cryo-ET

    Article • Microscopy and Microanalysis, July 2010, Oxford University Press (OUP)

    Rebecca C Craven, Bernard Heymann

  56. Analysis of Simian Virus 40 Chromatin Structure by Cryo-Electron Tomography

    Article • Microscopy and Microanalysis, July 2009, Oxford University Press (OUP)

    Bernard Heymann

  57. Electron Cryo-Tomography Demonstrates Variable Distributions of the Viral NTPase and RNA Polymerase in Bacteriophage φ6 Procapsids

    Article • Microscopy and Microanalysis, July 2009, Oxford University Press (OUP)

    Bernard Heymann

  58. Expansion of the Bacteriophage φ6 Procapsid Revealed by Electron Cryo-Microscopy

    Article • Microscopy and Microanalysis, July 2009, Oxford University Press (OUP)

    Bernard Heymann

  59. Image Processing and Interpretation in Structural Electron Microscopy

    Article • Microscopy and Microanalysis, July 2009, Oxford University Press (OUP)

    Bernard Heymann

  60. Initial Stages of V(D)J Recombination: The Organization of RAG1/2 and RSS DNA in the Postcleavage Complex

    Article • Molecular Cell, July 2009, Elsevier

    Bernard Heymann

  61. Capsid Polymorphism of Rous Sarcoma Virus Correlates with Assembly Efficiency and Envelope Glycoprotein Content

    Article • Microscopy and Microanalysis, August 2008, Oxford University Press (OUP)

    Bernard Heymann

  62. Cryo-Electron Tomography of Coated Vesicles and Modeling the Polyhedral Clathrin Network

    Article • Microscopy and Microanalysis, August 2008, Oxford University Press (OUP)

    Bernard Heymann

  63. Packaging of Proteins into Viral Capsids and their Activation

    Article • Microscopy and Microanalysis, August 2008, Oxford University Press (OUP)

    Bernard Heymann

  64. Initial Location of the RNA-dependent RNA Polymerase in the Bacteriophage Φ6 Procapsid Determined by Cryo-electron Microscopy

    Article • Journal of Biological Chemistry, May 2008, Elsevier

    Bernard Heymann

  65. Computational resources for cryo-electron tomography in Bsoft

    Article • Journal of Structural Biology, March 2008, Elsevier

    Bernard Heymann

  66. RSV Capsid Polymorphism Correlates with Polymerization Efficiency and Envelope Glycoprotein Content: Implications that Nucleation Controls Morphogenesis

    Article • Journal of Molecular Biology, February 2008, Elsevier

    Rebecca C Craven, Bernard Heymann

  67. Irregular and Semi-Regular Polyhedral Models for Rous Sarcoma Virus Cores

    Article • Computational and Mathematical Methods in Medicine, January 2008, Hindawi Publishing Corporation

    Bernard Heymann

  68. RNA Packing in Bacteriophage φ6 Visualized by Cryo-Electron Microscopy

    Article • Microscopy and Microanalysis, August 2007, Oxford University Press (OUP)

    Bernard Heymann

  69. Bsoft: Image processing and molecular modeling for electron microscopy

    Article • Journal of Structural Biology, January 2007, Elsevier

    Bernard Heymann

  70. Influenza virus pleiomorphy characterized by cryoelectron tomography

    Article • Proceedings of the National Academy of Sciences, December 2006, Proceedings of the National Academy of Sciences

    Bernard Heymann

  71. Outcome of a Workshop on Archiving Structural Models of Biological Macromolecules

    Article • Structure, August 2006, Elsevier

    Bernard Heymann

  72. Visualizing the Clathrin and Assembly-Regulating Proteins of Coated Vesicles by Cryo-Electron Tomography

    Article • Microscopy and Microanalysis, July 2006, Oxford University Press (OUP)

    Bernard Heymann

  73. A comparison of liquid nitrogen and liquid helium as cryogens for electron cryotomography

    Article • Journal of Structural Biology, March 2006, Elsevier

    Bernard Heymann

  74. Corrigendum to “Common conventions for interchange and archiving of three-dimensional electron microscopy information in structural biology” [J. Struct. Biol. 151 (2005) 196–207]

    Article • Journal of Structural Biology, March 2006, Elsevier

    Bernard Heymann

  75. A “flip–flop” rotation stage for routine dual-axis electron cryotomography

    Article • Journal of Structural Biology, September 2005, Elsevier

    Bernard Heymann

  76. Dynamics of the Protrusion Domain of Herpes Simplex Virus Capsid from Time-Resolved Cryo-EM and Molecular Modelling

    Article • Microscopy and Microanalysis, August 2005, Oxford University Press (OUP)

    Bernard Heymann

  77. Recent Advances in Electron Cryotomography and their Application to Imaging Purified Protein Complexes, Isolated Organelles, and Small Cells

    Article • Microscopy and Microanalysis, August 2005, Oxford University Press (OUP)

    Bernard Heymann

  78. Common conventions for interchange and archiving of three-dimensional electron microscopy information in structural biology

    Article • Journal of Structural Biology, August 2005, Elsevier

    Bernard Heymann

  79. Peach: A Simple Perl-Based System for Distributed Computation and Its Application to Cryo-EM Data Processing

    Article • Structure, April 2005, Elsevier

    Bernard Heymann

  80. Virus maturation: dynamics and mechanism of a stabilizing structural transition that leads to infectivity

    Article • Current Opinion in Structural Biology, April 2005, Elsevier

    Bernard Heymann

  81. The Axial Channel of the 20S Proteasome Opens Upon Binding of the PA200 Activator

    Article • Journal of Molecular Biology, March 2005, Elsevier

    Bernard Heymann

  82. Visualization of the Binding of Hsc70 ATPase to Clathrin Baskets

    Article • Journal of Biological Chemistry, February 2005, Elsevier

    Bernard Heymann

  83. Molecular dynamics of protein complexes from four-dimensional cryo-electron microscopy

    Article • Journal of Structural Biology, September 2004, Elsevier

    Bernard Heymann

  84. Macro Molecular Dynamics by Multiple Particle Analysis: Classifying Distinct Conformational States by Generalized Projection Matching

    Article • Microscopy and Microanalysis, August 2004, Oxford University Press (OUP)

    Bernard Heymann

  85. Three-Dimensional Structure of Herpes Simplex Virus from Cryo-Electron Tomography

    Article • Science, November 2003, American Association for the Advancement of Science

    Bernard Heymann

  86. Dynamics of herpes simplex virus capsid maturation visualized by time-lapse cryo-electron microscopy

    Article • Nature Structural & Molecular Biology, April 2003, Springer Science + Business Media

    Bernard Heymann

  87. Herpes Simplex Virus Capsid Maturation Visualized by Time-Lapsed Cryo-EM

    Article • Microscopy and Microanalysis, August 2002, Oxford University Press (OUP)

    Bernard Heymann

  88. Sampling effects influence heights measured with atomic force microscopy

    Article • Journal of Microscopy, July 2002, Wiley

    Bernard Heymann

  89. Molecular basis of water selectivity on aquaporin-1

    Article • Kidney International, August 2001, Elsevier

    Bernard Heymann

  90. Capsid Structure of Kaposi's Sarcoma-Associated Herpesvirus, a Gammaherpesvirus, Compared to Those of an Alphaherpesvirus, Herpes Simplex Virus Type 1, and a Betaherpesvirus, Cytomegalovirus

    Article • Journal of Virology, March 2001, ASM Journals

    Bernard Heymann

  91. Bsoft: Image and Molecular Processing in Electron Microscopy

    Article • Journal of Structural Biology, February 2001, Elsevier

    Bernard Heymann

  92. Structural determinants of water permeation through aquaporin-1

    Article • Nature, October 2000, Springer Science + Business Media

    Bernard Heymann

  93. Folded State of the Integral Membrane Colicin E1 Immunity Protein in Solvents of Mixed Polarity

    Article • Biochemistry, September 2000, American Chemical Society (ACS)

    Bernard Heymann

  94. Atomic force microscopy of native purple membrane

    Article • Biochimica et Biophysica Acta (BBA) - Bioenergetics, August 2000, Elsevier

    Bernard Heymann

  95. The Fold of Human Aquaporin 1

    Article • Journal of Molecular Biology, July 2000, Elsevier

    Bernard Heymann

  96. Conformations of the rhodopsin third cytoplasmic loop grafted onto bacteriorhodopsin

    Article • Structure, June 2000, Elsevier

    Bernard Heymann

  97. Structural clues in the sequences of the aquaporins

    Article • Journal of Molecular Biology, January 2000, Elsevier

    Bernard Heymann

  98. The Structure of Aquaporin-1 at 4.5-Å Resolution Reveals Short α-Helices in the Center of the Monomer

    Article • Journal of Structural Biology, December 1999, Elsevier

    Bernard Heymann

  99. Charting the Surfaces of the Purple Membrane

    Article • Journal of Structural Biology, December 1999, Elsevier

    Bernard Heymann

  100. Aquaporins: Phylogeny, Structure, and Physiology of Water Channels

    Article • Physiology, October 1999, American Physiological Society

    Bernard Heymann

  101. Visualizing 3D Data Obtained from Microscopy on the Internet

    Article • Journal of Structural Biology, April 1999, Elsevier

    Bernard Heymann

  102. Imaging streptavidin 2D crystals on biotinylated lipid monolayers at high resolution with the atomic force microscope

    Article • Journal of Microscopy, January 1999, Wiley

    Bernard Heymann

  103. Organising multi-dimensional biological image information: The BioImage Database

    Article • Nucleic Acids Research, January 1999, Oxford University Press (OUP)

    Bernard Heymann

  104. 2D Crystallization of Membrane Proteins: Rationales and Examples

    Article • Journal of Structural Biology, January 1998, Elsevier

    Bernard Heymann

  105. Progress on the Structure and Function of Aquaporin 1

    Article • Journal of Structural Biology, January 1998, Elsevier

    Bernard Heymann

  106. Electron and atomic force microscopy of membrane proteins

    Article • Current Opinion in Structural Biology, August 1997, Elsevier

    Bernard Heymann

  107. The three-dimensional structure of aquaporin-1

    Article • Nature, June 1997, Springer Science + Business Media

    Bernard Heymann

  108. Characterization of the Chloroplast Cytochrome b6f Complex as a Structural and Functional Dimer

    Article • Biochemistry, April 1994, American Chemical Society (ACS)

    Bernard Heymann

  109. Structural aspects of the cytochromeb 6 f complex; structure of the lumen-side domain of cytochromef

    Article • Journal of Bioenergetics and Biomembranes, February 1994, Springer Science + Business Media

    Bernard Heymann