All Stories

  1. Phosphorylation of the VAR2CSA extracellular region is associated with enhanced adhesive properties to the placental receptor CSA
  2. The sickle cell trait affects contact dynamics and endothelial cell activation in Plasmodium falciparum-infected erythrocytes
  3. Down-selection of the VAR2CSA DBL1-2 expressed in E. coli as a lead antigen for placental malaria vaccine development
  4. Optimization of incubation conditions of Plasmodium falciparum antibody multiplex assays to measure IgG, IgG1–4, IgM and IgE using standard and customized reference pools for sero-epidemiological and vaccine studies
  5. Host factors that modify Plasmodium falciparum adhesion to endothelial receptors
  6. Parasites Causing Cerebral Falciparum Malaria Bind Multiple Endothelial Receptors and Express EPCR and ICAM-1-Binding PfEMP1
  7. Heterozygous HbAC but not HbAS is associated with higher newborn birthweight among women with pregnancy-associated malaria
  8. Structure-Guided Identification of a Family of Dual Receptor-Binding PfEMP1 that Is Associated with Cerebral Malaria
  9. TSPO ligands stimulate ZnPPIX transport and ROS accumulation leading to the inhibition of P. falciparum growth in human blood
  10. Clinical development of placental malaria vaccines and immunoassays harmonization: a workshop report
  11. Murine Model for Preclinical Studies of Var2CSA-Mediated Pathology Associated with Malaria in Pregnancy
  12. Erratum to: Beninese children with cerebral malaria do not develop humoral immunity against the IT4-VAR19-DC8 PfEMP1 variant linked to EPCR and brain endothelial binding
  13. Beninese children with cerebral malaria do not develop humoral immunity against the IT4-VAR19-DC8 PfEMP1 variant linked to EPCR and brain endothelial binding
  14. Structure of the DBL3X-DBL4ε region of the VAR2CSA placental malaria vaccine candidate: insight into DBL domain interactions
  15. Parity-Dependent Recognition of DBL1X-3X Suggests an Important Role of the VAR2CSA High-Affinity CSA-Binding Region in the Development of the Humoral Response against Placental Malaria
  16. Crystal structure of the DBL3X-DBL4epsilon double domain from the extracellular part of VAR2CSA PfEMP1 from Plasmodium falciparum
  17. Llama immunization with full-length VAR2CSA generates cross-reactive and inhibitory single-domain antibodies against the DBL1X domain
  18. High-Throughput Screening Platform Identifies Small Molecules That Prevent Sequestration ofPlasmodium falciparum–Infected Erythrocytes
  19. Placental Cytokine and Chemokine Profiles Reflect Pregnancy Outcomes in Women Exposed to Plasmodium falciparum Infection
  20. Production, crystallization and X-ray diffraction analysis of two nanobodies against the Duffy binding-like (DBL) domain DBL6∊-FCR3 of thePlasmodium falciparumVAR2CSA protein. Corrigendum
  21. Structural and Immunological Correlations between the Variable Blocks of the VAR2CSA Domain DBL6ε from Two Plasmodium falciparum Parasite Lines
  22. Production, crystallization and X-ray diffraction analysis of two nanobodies against the Duffy binding-like (DBL) domain DBL6∊-FCR3 of thePlasmodium falciparumVAR2CSA protein
  23. Expressing Full-Length Functional PfEMP1 Proteins in the HEK293 Expression System
  24. Var2CSA Minimal CSA Binding Region Is Located within the N-Terminal Region
  25. Antibodies to a Full-Length VAR2CSA Immunogen Are Broadly Strain-Transcendent but Do Not Cross-Inhibit Different Placental-Type Parasite Isolates
  26. Full-length extracellular region of the var2CSA variant of PfEMP1 is required for specific, high-affinity binding to CSA
  27. How does Plasmodium falciparum stick to CSA? Let's see in the crystal
  28. Investigation of host factors possibly enhancing the emergence of the chondroitin sulfate A-binding phenotype in Plasmodium falciparum
  29. Var2CSA DBL6-epsilon domain expressed in HEK293 induces limited cross-reactive and blocking antibodies to CSA binding parasites
  30. Structural polymorphism and diversifying selection on the pregnancy malaria vaccine candidate VAR2CSA
  31. Disruption of Var2csa Gene Impairs Placental Malaria Associated Adhesion Phenotype
  32. Pregnancy-associated malaria: Parasite binding, natural immunity and vaccine development
  33. Characterization of anti-var2CSA-PfEMP1 cytoadhesion inhibitory mouse monoclonal antibodies
  34. The human placental derived BeWo cell line: A useful model for selecting Plasmodium falciparum CSA-binding parasites
  35. A single member of the Plasmodium falciparum var multigene family determines cytoadhesion to the placental receptor chondroitin sulphate A
  36. Identification of Multiple Chondroitin Sulfate A (CSA)–Binding Domains in the var2CSA Gene Transcribed in CSA‐Binding Parasites
  37. Identification of a 67-amino-acid region of the Plasmodium falciparum variant surface antigen that binds chondroitin sulphate A and elicits antibodies reactive with the surface of placental isolates
  38. Induction of crossreactive antibodies against the Plasmodium falciparum variant protein
  39. DNA Immunization with the Cysteine-Rich Interdomain Region 1 of the Plasmodium falciparum Variant Antigen Elicits Limited Cross-Reactive Antibody Responses
  40. Molecular basis for the dichotomy in Plasmodium falciparum adhesion to CD36 and chondroitin sulfate A
  41. Definition of the minimal domain of CIDR1α of Plasmodium falciparum PfEMP1 for binding CD36
  42. Immunization of Aotus monkeys with a functional domain of the Plasmodium falciparum variant antigen induces protection against a lethal parasite line
  43. Decoding the language of var genes and Plasmodium falciparum sequestration
  44. Modifications in the CD36 binding domain of the Plasmodium falciparum variant antigen are responsible for the inability of chondroitin sulfate A adherent parasites to bind CD36
  45. The surface variant antigens of Plasmodium falciparum contain cross-reactive epitopes
  46. The Putative Glutathione Peroxidase Gene of Plasmodium falciparum Codes for a Thioredoxin Peroxidase
  47. Classification of adhesive domains in the Plasmodium falciparum Erythrocyte Membrane Protein 1 family
  48. Plasmodium falciparum domain mediating adhesion to chondroitin sulfate A: A receptor for human placental infection
  49. Babesia hylomysci and B. divergens : presence of antioxidant enzymes destroying hydrogen peroxide
  50. Molecular characterization of the glutathione peroxidase gene of the human malaria parasite Plasmodium falciparum
  51. The course of Plasmodium berghei, P. chabaudi and P. yoelii infections in β-thalassaemic mice
  52. Increase in glutathione peroxidase activity in malaria parasite after selenium supplementation