All Stories

  1. Bioactive compounds in European ferns: inhibition of pro-inflammatory enzymes and cytotoxic effects on cancer cells
  2. Flubendazole carbonyl reduction in drug-susceptible and drug-resistant strains of the parasitic nematode Haemonchus contortus: changes during the life cycle and possible inhibition
  3. Anthelmintic activity of European fern extracts against Haemonchus contortus
  4. Albendazole from ovine excrements in soil and plants under real agricultural conditions: Distribution, persistence, and effects
  5. Environmental circulation of the anthelmintic drug albendazole affects expression and activity of resistance-related genes in the parasitic nematode Haemonchus contortus
  6. Albendazole from Ovine Excrements in Soil and Plants Under Real Agricultural Conditions: Distribution, Persistence, and Effects
  7. Proof of the environmental circulation of veterinary drug albendazole in real farm conditions
  8. Soybean (Glycine max) Is Able to Absorb, Metabolize and Accumulate Fenbendazole in All Organs Including Beans
  9. Leaves and Fruits Preparations of Pistacia lentiscus L.: A Review on the Ethnopharmacological Uses and Implications in Inflammation and Infection
  10. <em>Pistacia lentiscus</em>: From Phytopharmacology to Scientific Explanations on Its Anti-Inflammatory and Antimicrobial Capacity
  11. The Identification of Metabolites and Effects of Albendazole in Alfalfa (Medicago sativa)
  12. The Uptake of Ivermectin and Its Effects in Roots, Leaves and Seeds of Soybean (Glycine max)
  13. Sub-lethal doses of albendazole induce drug metabolizing enzymes and increase albendazole deactivation in Haemonchus contortus adults
  14. The Modulation of Phase II Drug-Metabolizing Enzymes in Proliferating and Differentiated CaCo-2 Cells by Hop-Derived Prenylflavonoids
  15. Pharmaceuticals in environment: the effect of ivermectin on ribwort plantain (Plantago lanceolata L.)
  16. The Pharmaceutical Ability of Pistacia lentiscus L. Leaves Essential Oil Against Periodontal Bacteria and Candida sp. and Its Anti-Inflammatory Potential
  17. The Pharmaceutical Ability of <em>Pistacia lentiscus</em> L. Leaves Essential Oil against Periodontal Bacteria and Candida sp. and Its Anti-inflammatory Potential
  18. The uptake, effects and biotransformation of monepantel in meadow plants used as a livestock feed
  19. Ivermectin biotransformation and impact on transcriptome in Arabidopsis thaliana
  20. Ivermectin-induced changes in the expression of cytochromes P450 and efflux transporters in Haemonchus contortus female and male adults
  21. Effect of bilberry extract (Vaccinium myrtillus L.) on drug-metabolizing enzymes in rats
  22. Carbonyl Reduction of Flubendazole in the Human Liver: Strict Stereospecificity, Sex Difference, Low Risk of Drug Interactions
  23. Ivermectin environmental impact: Excretion profile in sheep and phytotoxic effect in Sinapis alba
  24. Metabolism of the anthelmintic drug fenbendazole in Arabidopsis thaliana and its effect on transcriptome and proteome
  25. UDP-glycosyltransferase family in Haemonchus contortus: Phylogenetic analysis, constitutive expression, sex-differences and resistance-related differences
  26. Metabolism of albendazole, ricobendazole and flubendazole in Haemonchus contortus adults: Sex differences, resistance-related differences and the identification of new metabolites
  27. Induction of xenobiotic-metabolizing enzymes in hepatocytes by beta-naphthoflavone: Time-dependent changes in activities, protein and mRNA levels
  28. Biotransformation of flubendazole and fenbendazole and their effects in the ribwort plantain (Plantago lanceolata)
  29. The inhibitory effects of β-caryophyllene, β-caryophyllene oxide and α-humulene on the activities of the main drug-metabolizing enzymes in rat and human liver in vitro
  30. Sulforaphane Alters β-Naphthoflavone-Induced Changes in Activity and Expression of Drug-Metabolizing Enzymes in Rat Hepatocytes
  31. Evaluation of drug uptake and deactivation in plant: Fate of albendazole in ribwort plantain (Plantago laceolata) cells and regenerants
  32. Design, Synthesis, and Biological Evaluation of Isothiosemicarbazones with Antimycobacterial Activity
  33. Nerolidol and Farnesol Inhibit Some Cytochrome P450 Activities but Did Not Affect Other Xenobiotic-Metabolizing Enzymes in Rat and Human Hepatic Subcellular Fractions
  34. Effect of Green Tea Extract-Enriched Diets on Insulin and Leptin Levels, Oxidative Stress Parameters and Antioxidant Enzymes Activities in Obese Mice
  35. Catechins Variously Affect Activities of Conjugation Enzymes in Proliferating and Differentiated Caco-2 Cells
  36. Metabolic pathways of benzimidazole anthelmintics in harebell (Campanula rotundifolia)
  37. Albendazole in environment: faecal concentrations in lambs and impact on lower development stages of helminths and seed germination
  38. Cranberry extract–enriched diets increase NAD(P)H:quinone oxidoreductase and catalase activities in obese but not in nonobese mice
  39. The Influence of Sesquiterpenes from Myrica rubra on the Antiproliferative and Pro-Oxidative Effects of Doxorubicin and Its Accumulation in Cancer Cells
  40. Metabolism of drugs and other xenobiotics in giant liver fluke (Fascioloides magna)
  41. Reliable reference gene selection for quantitative real time PCR in Haemonchus contortus
  42. Comparison of biotransformation and efficacy of aminoacetonitrile anthelmintics in vitro
  43. Effect of oral administration of green tea extract in various dosage schemes on oxidative stress status of mice in vivo
  44. Influence of diet supplementation with green tea extract on drug-metabolizing enzymes in a mouse model of monosodium glutamate-induced obesity
  45. Monepantel induces hepatic cytochromes p450 in sheep in vitro and in vivo
  46. Drug-Metabolizing and Antioxidant Enzymes in Monosodium L-Glutamate Obese Mice
  47. Biotransformation of anthelmintics in tapeworm Moniezia expansa
  48. Characterization of Tetratricopeptide Repeat-Like Proteins in Francisella tularensis and Identification of a Novel Locus Required for Virulence
  49. Effect of Standardized Cranberry Extract on the Activity and Expression of Selected Biotransformation Enzymes in Rat Liver and Intestine
  50. Effect of defined green tea extract in various dosage schemes on drug-metabolizing enzymes in mice in vivo
  51. Metabolic pathways of anthelmintic drug monepantel in sheep and in its parasite (Haemonchus contortus)
  52. Reference Genes for Real-Time PCR Quantification of Messenger RNAs and MicroRNAs in Mouse Model of Obesity
  53. Francisella tularensis subsp. holarctica DsbA homologue: a thioredoxin-like protein with chaperone function
  54. Biotransformation of albendazole and activities of selected detoxification enzymes in Haemonchus contortus strains susceptible and resistant to anthelmintics
  55. Biotransformation of benzimidazole anthelmintics in reed (Phragmites australis) as a potential tool for their detoxification in environment
  56. Analytical power of LLE–HPLC–PDA–MS/MS in drug metabolism studies: Identification of new nabumetone metabolites
  57. Inhibitory effect of anthocyanidins on hepatic glutathione S-transferase, UDP-glucuronosyltransferase and carbonyl reductase activities in rat and human
  58. Age-Related Changes in Hepatic Activity and Expression of Detoxification Enzymes in Male Rats
  59. Investigation of the metabolism of monepantel in ovine hepatocytes by UHPLC/MS/MS
  60. The metabolic fate of ivermectin in host (Ovis aries) and parasite (Haemonchus contortus)
  61. Import and efflux of flubendazole in Haemonchus contortus strains susceptible and resistant to anthelmintics
  62. The metabolism of flubendazole and the activities of selected biotransformation enzymes in Haemonchus contortus strains susceptible and resistant to anthelmintics
  63. The inability of tapeworm Hymenolepis diminuta and fluke Dicrocoelium dendriticum to metabolize praziquantel
  64. The activity of drug-metabolizing enzymes and the biotransformation of selected anthelmintics in the model tapeworm Hymenolepis diminuta
  65. High-performance liquid chromatographic determination of tiapride and its phase I metabolite in blood plasma using tandem UV photodiode-array and fluorescence detection
  66. The transport of albendazole and albendazole sulphoxide in the lancet fluke (Dicrocoelium dendriticum)
  67. The effects of flubendazole and its metabolites on the larval development of Haemonchus contortus (Nematoda: Trichostrongylidae): an in vitro study
  68. Effect of Flubendazole on Biotransformation Enzymes Activities in Haemonchus contortus~!2010-03-18~!2010-06-16~!2010-08-07~!
  69. In vitrooxidative metabolism of xenobiotics in the lancet fluke (Dicrocoelium dendriticum) and the effects of albendazole and albendazole sulphoxideex vivo
  70. Activities of biotransformation enzymes and flubendazole metabolism in lambs (Ovis aries): effect of gender and flubendazole therapy
  71. Flubendazole metabolism and biotransformation enzymes activities in healthy sheep and sheep with haemonchosis
  72. Pharmacokinetics of flubendazole and its metabolites in lambs and adult sheep (Ovis aries)
  73. Liquid chromatography/mass spectrometric identification of benzimidazole anthelminthics metabolites formed ex vivo by Dicrocoelium dendriticum
  74. The role of aryl hydrocarbon receptor in regulation of enzymes involved in metabolic activation of polycyclic aromatic hydrocarbons in a model of rat liver progenitor cells
  75. Phase I biotransformation of albendazole in lancet fluke (Dicrocoelium dendriticum)
  76. Characterization of metabolites of sibutramine in primary cultures of rat hepatocytes by liquid chromatography–ion trap mass spectrometry
  77. Sensitive chiral high-performance liquid chromatographic determination of anthelmintic flubendazole and its phase I metabolites in blood plasma using UV photodiode-array and fluorescence detection
  78. LC with Fluorimetric Detection for Sensitive Analysis of Reduced Flubendazole in Biological Samples
  79. LC–MS–MS identification of albendazole and flubendazole metabolites formed ex vivo by Haemonchus contortus
  80. Biotransformation of flubendazole and selected model xenobiotics in Haemonchus contortus
  81. Modulation of Porcine (Sus scrofa domestica) and Pheasant (Phasianus colchicus) Carbonyl Reducing Enzymes by Anthelmintic Therapy with Flubendazole
  82. Aldo-keto reductases (AKR) from the AKR1C subfamily catalyze the carbonyl reduction of the novel anticancer drug oracin in man
  83. Activities of biotransformation enzymes in pheasant (Phasianus colchicus) and their modulation by in vivo administration of mebendazole and flubendazole
  84. Achiral and chiral high-performance liquid chromatographic determination of flubendazole and its metabolites in biomatrices using UV photodiode-array and mass spectrometric detection
  85. Mouflon (Ovis musimon) dicrocoeliosis: Effects of parasitosis on the activities of biotransformation enzymes and albendazole metabolism in liver
  86. Modulation of porcine biotransformation enzymes by anthelmintic therapy with fenbendazole and flubendazole
  87. The effects of flubendazole and mebendazole on cytochromes P4501A in pheasant hepatocytes
  88. Liver microsomal biotransformation of albendazole in deer, cattle, sheep and pig and some related wild breeds
  89. Albendazole repeated administration induces cytochromes P4501A and accelerates albendazole deactivation in mouflon (Ovis musimon)
  90. Use of chiral liquid chromatography for the evaluation of stereospecificity in the carbonyl reduction of potential benzo[c]fluorene antineoplastics benfluron and dimefluron in various species
  91. The stereoselective biotransformation of the anti-obesity drug sibutramine in rat liver microsomes and in primary cultures of rat hepatocytes
  92. Chiral Inversion of Drugs: Coincidence or Principle?
  93. The novel anticancer drug oracin: different stereospecificity and cooperativity for carbonyl reduction by purified human liver 11β-hydroxysteroid dehydrogenase type 1
  94. The effects of fenbendazole, flubendazole and mebendazole on activities of hepatic cytochromes P450 in pig
  95. Characterization of enzymes responsible for biotransformation of the new antileukotrienic drug quinlukast in rat liver microsomes and in primary cultures of rat hepatocytes
  96. Comparison of in vitro activities of biotransformation enzymes in pig, cattle, goat and sheep
  97. The Phase I Biotransformation of the Potential Antileukotrienic Drug Quinlukast in Rat Microsomes and Hepatocytes
  98. Stereospecificity of flobufen metabolism in guinea pigs in vitro and in vivo: Phase I of biotransformation
  99. Inter-species comparisons of hepatic cytochrome P450 enzyme levels in male ruminants
  100. Stereospecific biotransformation of albendazole in mouflon and rat‐isolated hepatocytes
  101. Stereospecific reduction of the original anticancer drug oracin in rat extrahepatic tissues
  102. Stereochemical aspects of carbonyl reduction of the original anticancer drug oracin by mouse liver microsomes and purified 11β-hydroxysteroid dehydrogenase type 1
  103. Chiral aspects of metabolism of antiinflammatory drug flobufen in human hepatocytes
  104. Reduction of flobufen in pig hepatocytes: Effect of pig breed (domestic, wild) and castration
  105. Carbonyl reduction of the potential cytostatic drugs benfluron and 3,9-dimethoxybenfluron in human in vitro
  106. Effect of ivermectin on activities of cytochrome P450 isoenzymes in mouflon (Ovis musimon) and fallow deer (Dama dama)
  107. Biotransformation of flobufen enantiomers in ruminant hepatocytes and subcellular fractions
  108. Stereospecificity and stereoselectivity of flobufen metabolic profile in male rats in vitro and in vivo: Phase I of biotransformation
  109. Effect of substituents on microsomal reduction of benzo(c)fluorene N-oxides
  110. Reduction of the Potential Anticancer Drug Oracin in the Rat Liver In-vitro
  111. Activity, stereospecificity, and stereoselectivity of microsomal enzymes in dependence on storage and freezing of rat liver samples
  112. A comparison between stereospecificity of oracin reduction and stereoselectivity of oxidation of 11-dihydrooracin enantiomersin vitro in rat and guinea pig
  113. Sex differences in stereospecificity of oracin reductases in ratin vitro andin vivo
  114. Stereoselective pharmacokinetics of flobufen in rats
  115. High-performance liquid chromatography study of stereospecific microsomal enzymes catalysing the reduction of a potential cytostatic drug, oracin
  116. High-performance liquid chromatographic assay for the separation and characterization of metabolites of the potential cytostatic drug oracine