All Stories

  1. Bioactive compounds in European ferns: inhibition of pro-inflammatory enzymes and cytotoxic effects on cancer cells
  2. Flubendazole carbonyl reduction in drug-susceptible and drug-resistant strains of the parasitic nematode Haemonchus contortus: changes during the life cycle and possible inhibition
  3. Anthelmintic activity of European fern extracts against Haemonchus contortus
  4. Albendazole from ovine excrements in soil and plants under real agricultural conditions: Distribution, persistence, and effects
  5. Environmental circulation of the anthelmintic drug albendazole affects expression and activity of resistance-related genes in the parasitic nematode Haemonchus contortus
  6. Proof of the environmental circulation of veterinary drug albendazole in real farm conditions
  7. Soybean (Glycine max) Is Able to Absorb, Metabolize and Accumulate Fenbendazole in All Organs Including Beans
  8. Leaves and Fruits Preparations of Pistacia lentiscus L.: A Review on the Ethnopharmacological Uses and Implications in Inflammation and Infection
  9. <em>Pistacia lentiscus</em>: From Phytopharmacology to Scientific Explanations on Its Anti-Inflammatory and Antimicrobial Capacity
  10. The Identification of Metabolites and Effects of Albendazole in Alfalfa (Medicago sativa)
  11. The Uptake of Ivermectin and Its Effects in Roots, Leaves and Seeds of Soybean (Glycine max)
  12. Sub-lethal doses of albendazole induce drug metabolizing enzymes and increase albendazole deactivation in Haemonchus contortus adults
  13. The Modulation of Phase II Drug-Metabolizing Enzymes in Proliferating and Differentiated CaCo-2 Cells by Hop-Derived Prenylflavonoids
  14. Pharmaceuticals in environment: the effect of ivermectin on ribwort plantain (Plantago lanceolata L.)
  15. The Pharmaceutical Ability of Pistacia lentiscus L. Leaves Essential Oil Against Periodontal Bacteria and Candida sp. and Its Anti-Inflammatory Potential
  16. The Pharmaceutical Ability of <em>Pistacia lentiscus</em> L. Leaves Essential Oil against Periodontal Bacteria and Candida sp. and Its Anti-inflammatory Potential
  17. The uptake, effects and biotransformation of monepantel in meadow plants used as a livestock feed
  18. Ivermectin biotransformation and impact on transcriptome in Arabidopsis thaliana
  19. Ivermectin-induced changes in the expression of cytochromes P450 and efflux transporters in Haemonchus contortus female and male adults
  20. Effect of bilberry extract (Vaccinium myrtillus L.) on drug-metabolizing enzymes in rats
  21. Carbonyl Reduction of Flubendazole in the Human Liver: Strict Stereospecificity, Sex Difference, Low Risk of Drug Interactions
  22. Ivermectin environmental impact: Excretion profile in sheep and phytotoxic effect in Sinapis alba
  23. Metabolism of the anthelmintic drug fenbendazole in Arabidopsis thaliana and its effect on transcriptome and proteome
  24. UDP-glycosyltransferase family in Haemonchus contortus: Phylogenetic analysis, constitutive expression, sex-differences and resistance-related differences
  25. Metabolism of albendazole, ricobendazole and flubendazole in Haemonchus contortus adults: Sex differences, resistance-related differences and the identification of new metabolites
  26. Induction of xenobiotic-metabolizing enzymes in hepatocytes by beta-naphthoflavone: Time-dependent changes in activities, protein and mRNA levels
  27. Biotransformation of flubendazole and fenbendazole and their effects in the ribwort plantain (Plantago lanceolata)
  28. The inhibitory effects of β-caryophyllene, β-caryophyllene oxide and α-humulene on the activities of the main drug-metabolizing enzymes in rat and human liver in vitro
  29. Sulforaphane Alters β-Naphthoflavone-Induced Changes in Activity and Expression of Drug-Metabolizing Enzymes in Rat Hepatocytes
  30. Evaluation of drug uptake and deactivation in plant: Fate of albendazole in ribwort plantain (Plantago laceolata) cells and regenerants
  31. Design, Synthesis, and Biological Evaluation of Isothiosemicarbazones with Antimycobacterial Activity
  32. Nerolidol and Farnesol Inhibit Some Cytochrome P450 Activities but Did Not Affect Other Xenobiotic-Metabolizing Enzymes in Rat and Human Hepatic Subcellular Fractions
  33. Effect of Green Tea Extract-Enriched Diets on Insulin and Leptin Levels, Oxidative Stress Parameters and Antioxidant Enzymes Activities in Obese Mice
  34. Catechins Variously Affect Activities of Conjugation Enzymes in Proliferating and Differentiated Caco-2 Cells
  35. Metabolic pathways of benzimidazole anthelmintics in harebell (Campanula rotundifolia)
  36. Albendazole in environment: faecal concentrations in lambs and impact on lower development stages of helminths and seed germination
  37. Cranberry extract–enriched diets increase NAD(P)H:quinone oxidoreductase and catalase activities in obese but not in nonobese mice
  38. The Influence of Sesquiterpenes from Myrica rubra on the Antiproliferative and Pro-Oxidative Effects of Doxorubicin and Its Accumulation in Cancer Cells
  39. Metabolism of drugs and other xenobiotics in giant liver fluke (Fascioloides magna)
  40. Reliable reference gene selection for quantitative real time PCR in Haemonchus contortus
  41. Comparison of biotransformation and efficacy of aminoacetonitrile anthelmintics in vitro
  42. Effect of oral administration of green tea extract in various dosage schemes on oxidative stress status of mice in vivo
  43. Influence of diet supplementation with green tea extract on drug-metabolizing enzymes in a mouse model of monosodium glutamate-induced obesity
  44. Monepantel induces hepatic cytochromes p450 in sheep in vitro and in vivo
  45. Drug-Metabolizing and Antioxidant Enzymes in Monosodium L-Glutamate Obese Mice
  46. Biotransformation of anthelmintics in tapeworm Moniezia expansa
  47. Characterization of Tetratricopeptide Repeat-Like Proteins in Francisella tularensis and Identification of a Novel Locus Required for Virulence
  48. Effect of Standardized Cranberry Extract on the Activity and Expression of Selected Biotransformation Enzymes in Rat Liver and Intestine
  49. Effect of defined green tea extract in various dosage schemes on drug-metabolizing enzymes in mice in vivo
  50. Metabolic pathways of anthelmintic drug monepantel in sheep and in its parasite (Haemonchus contortus)
  51. Reference Genes for Real-Time PCR Quantification of Messenger RNAs and MicroRNAs in Mouse Model of Obesity
  52. Francisella tularensis subsp. holarctica DsbA homologue: a thioredoxin-like protein with chaperone function
  53. Biotransformation of albendazole and activities of selected detoxification enzymes in Haemonchus contortus strains susceptible and resistant to anthelmintics
  54. Biotransformation of benzimidazole anthelmintics in reed (Phragmites australis) as a potential tool for their detoxification in environment
  55. Analytical power of LLE–HPLC–PDA–MS/MS in drug metabolism studies: Identification of new nabumetone metabolites
  56. Inhibitory effect of anthocyanidins on hepatic glutathione S-transferase, UDP-glucuronosyltransferase and carbonyl reductase activities in rat and human
  57. Age-Related Changes in Hepatic Activity and Expression of Detoxification Enzymes in Male Rats
  58. Investigation of the metabolism of monepantel in ovine hepatocytes by UHPLC/MS/MS
  59. The metabolic fate of ivermectin in host (Ovis aries) and parasite (Haemonchus contortus)
  60. Import and efflux of flubendazole in Haemonchus contortus strains susceptible and resistant to anthelmintics
  61. The metabolism of flubendazole and the activities of selected biotransformation enzymes in Haemonchus contortus strains susceptible and resistant to anthelmintics
  62. The inability of tapeworm Hymenolepis diminuta and fluke Dicrocoelium dendriticum to metabolize praziquantel
  63. The activity of drug-metabolizing enzymes and the biotransformation of selected anthelmintics in the model tapeworm Hymenolepis diminuta
  64. High-performance liquid chromatographic determination of tiapride and its phase I metabolite in blood plasma using tandem UV photodiode-array and fluorescence detection
  65. The transport of albendazole and albendazole sulphoxide in the lancet fluke (Dicrocoelium dendriticum)
  66. The effects of flubendazole and its metabolites on the larval development of Haemonchus contortus (Nematoda: Trichostrongylidae): an in vitro study
  67. Effect of Flubendazole on Biotransformation Enzymes Activities in Haemonchus contortus~!2010-03-18~!2010-06-16~!2010-08-07~!
  68. In vitrooxidative metabolism of xenobiotics in the lancet fluke (Dicrocoelium dendriticum) and the effects of albendazole and albendazole sulphoxideex vivo
  69. Activities of biotransformation enzymes and flubendazole metabolism in lambs (Ovis aries): effect of gender and flubendazole therapy
  70. Flubendazole metabolism and biotransformation enzymes activities in healthy sheep and sheep with haemonchosis
  71. Pharmacokinetics of flubendazole and its metabolites in lambs and adult sheep (Ovis aries)
  72. Liquid chromatography/mass spectrometric identification of benzimidazole anthelminthics metabolites formed ex vivo by Dicrocoelium dendriticum
  73. The role of aryl hydrocarbon receptor in regulation of enzymes involved in metabolic activation of polycyclic aromatic hydrocarbons in a model of rat liver progenitor cells
  74. Phase I biotransformation of albendazole in lancet fluke (Dicrocoelium dendriticum)
  75. Characterization of metabolites of sibutramine in primary cultures of rat hepatocytes by liquid chromatography–ion trap mass spectrometry
  76. Sensitive chiral high-performance liquid chromatographic determination of anthelmintic flubendazole and its phase I metabolites in blood plasma using UV photodiode-array and fluorescence detection
  77. LC with Fluorimetric Detection for Sensitive Analysis of Reduced Flubendazole in Biological Samples
  78. LC–MS–MS identification of albendazole and flubendazole metabolites formed ex vivo by Haemonchus contortus
  79. Biotransformation of flubendazole and selected model xenobiotics in Haemonchus contortus
  80. Modulation of Porcine (Sus scrofa domestica) and Pheasant (Phasianus colchicus) Carbonyl Reducing Enzymes by Anthelmintic Therapy with Flubendazole
  81. Aldo-keto reductases (AKR) from the AKR1C subfamily catalyze the carbonyl reduction of the novel anticancer drug oracin in man
  82. Activities of biotransformation enzymes in pheasant (Phasianus colchicus) and their modulation by in vivo administration of mebendazole and flubendazole
  83. Achiral and chiral high-performance liquid chromatographic determination of flubendazole and its metabolites in biomatrices using UV photodiode-array and mass spectrometric detection
  84. Mouflon (Ovis musimon) dicrocoeliosis: Effects of parasitosis on the activities of biotransformation enzymes and albendazole metabolism in liver
  85. Modulation of porcine biotransformation enzymes by anthelmintic therapy with fenbendazole and flubendazole
  86. The effects of flubendazole and mebendazole on cytochromes P4501A in pheasant hepatocytes
  87. Liver microsomal biotransformation of albendazole in deer, cattle, sheep and pig and some related wild breeds
  88. Albendazole repeated administration induces cytochromes P4501A and accelerates albendazole deactivation in mouflon (Ovis musimon)
  89. Use of chiral liquid chromatography for the evaluation of stereospecificity in the carbonyl reduction of potential benzo[c]fluorene antineoplastics benfluron and dimefluron in various species
  90. The stereoselective biotransformation of the anti-obesity drug sibutramine in rat liver microsomes and in primary cultures of rat hepatocytes
  91. Chiral Inversion of Drugs: Coincidence or Principle?
  92. The novel anticancer drug oracin: different stereospecificity and cooperativity for carbonyl reduction by purified human liver 11β-hydroxysteroid dehydrogenase type 1
  93. The effects of fenbendazole, flubendazole and mebendazole on activities of hepatic cytochromes P450 in pig
  94. Characterization of enzymes responsible for biotransformation of the new antileukotrienic drug quinlukast in rat liver microsomes and in primary cultures of rat hepatocytes
  95. Comparison of in vitro activities of biotransformation enzymes in pig, cattle, goat and sheep
  96. The Phase I Biotransformation of the Potential Antileukotrienic Drug Quinlukast in Rat Microsomes and Hepatocytes
  97. Stereospecificity of flobufen metabolism in guinea pigs in vitro and in vivo: Phase I of biotransformation
  98. Inter-species comparisons of hepatic cytochrome P450 enzyme levels in male ruminants
  99. Stereospecific biotransformation of albendazole in mouflon and rat‐isolated hepatocytes
  100. Stereospecific reduction of the original anticancer drug oracin in rat extrahepatic tissues
  101. Stereochemical aspects of carbonyl reduction of the original anticancer drug oracin by mouse liver microsomes and purified 11β-hydroxysteroid dehydrogenase type 1
  102. Chiral aspects of metabolism of antiinflammatory drug flobufen in human hepatocytes
  103. Reduction of flobufen in pig hepatocytes: Effect of pig breed (domestic, wild) and castration
  104. Carbonyl reduction of the potential cytostatic drugs benfluron and 3,9-dimethoxybenfluron in human in vitro
  105. Effect of ivermectin on activities of cytochrome P450 isoenzymes in mouflon (Ovis musimon) and fallow deer (Dama dama)
  106. Biotransformation of flobufen enantiomers in ruminant hepatocytes and subcellular fractions
  107. Stereospecificity and stereoselectivity of flobufen metabolic profile in male rats in vitro and in vivo: Phase I of biotransformation
  108. Effect of substituents on microsomal reduction of benzo(c)fluorene N-oxides
  109. Reduction of the Potential Anticancer Drug Oracin in the Rat Liver In-vitro
  110. Activity, stereospecificity, and stereoselectivity of microsomal enzymes in dependence on storage and freezing of rat liver samples
  111. A comparison between stereospecificity of oracin reduction and stereoselectivity of oxidation of 11-dihydrooracin enantiomersin vitro in rat and guinea pig
  112. Sex differences in stereospecificity of oracin reductases in ratin vitro andin vivo
  113. Stereoselective pharmacokinetics of flobufen in rats
  114. High-performance liquid chromatography study of stereospecific microsomal enzymes catalysing the reduction of a potential cytostatic drug, oracin
  115. High-performance liquid chromatographic assay for the separation and characterization of metabolites of the potential cytostatic drug oracine