All Stories

  1. Overcoming host restrictions to enable continuous passaging of GII.3 human norovirus in human intestinal enteroids

    Article • Science Advances, February 2026, American Association for the Advancement of Science

    Dr B Vijayalakshmi Ayyar

  2. Functional diversity in GII.4 norovirus entry: HBGA binding and capsid clustering dynamics

    Article • Proceedings of the National Academy of Sciences, October 2025, Proceedings of the National Academy of Sciences

    Dr Mary K Estes, Dr B Vijayalakshmi Ayyar

  3. Functional Diversity in GII.4 Norovirus Entry: HBGA Binding and Capsid Clustering Dynamics

    Article • May 2025, Cold Spring Harbor Laboratory Press

    Dr B Vijayalakshmi Ayyar

  4. RNA-dependent RNA polymerase of predominant human norovirus forms liquid-liquid phase condensates as viral replication factories

    Article • Science Advances, December 2024, American Association for the Advancement of Science

    Dr B Vijayalakshmi Ayyar

  5. A single nanobody neutralizes multiple epochally evolving human noroviruses by modulating capsid plasticity

    Article • Nature Communications, October 2023, Springer Science + Business Media

    Dr B Vijayalakshmi Ayyar

  6. CLIC and membrane wound repair pathways enable pandemic norovirus entry and infection

    Article • Nature Communications, February 2023, Springer Science + Business Media

    Dr B Vijayalakshmi Ayyar

  7. New Insights and Enhanced Human Norovirus Cultivation in Human Intestinal Enteroids

    Article • mSphere, January 2021, ASM Journals

    Dr B Vijayalakshmi Ayyar

  8. Human norovirus exhibits strain-specific sensitivity to host interferon pathways in human intestinal enteroids

    Article • Proceedings of the National Academy of Sciences, September 2020, Proceedings of the National Academy of Sciences

    Dr Mary K Estes, Dr B Vijayalakshmi Ayyar

  9. Genetic Manipulation of Human Intestinal Enteroids Demonstrates the Necessity of a Functional Fucosyltransferase 2 Gene for Secretor-Dependent Human Norovirus Infection

    Article • mBio, March 2020, ASM Journals

    Dr B Vijayalakshmi Ayyar

  10. Bile acids and ceramide overcome the entry restriction for GII.3 human norovirus replication in human intestinal enteroids

    Article • Proceedings of the National Academy of Sciences, January 2020, Proceedings of the National Academy of Sciences

    Dr B Vijayalakshmi Ayyar

  11. Comparison of Microneutralization and Histo-Blood Group Antigen–Blocking Assays for Functional Norovirus Antibody Detection

    Article • The Journal of Infectious Diseases, October 2019, Oxford University Press (OUP)

    Dr B Vijayalakshmi Ayyar

  12. Human Norovirus Cultivation in Nontransformed Stem Cell-Derived Human Intestinal Enteroid Cultures: Success and Challenges

    Article • Viruses, July 2019, MDPI AG

    Dr B Vijayalakshmi Ayyar

  13. Decoding Selection Bias Imparted by Unpaired Cysteines: a Tug of War Between Expression and Affinity

    Article • Applied Biochemistry and Biotechnology, January 2018, Springer Science + Business Media

    Dr B Vijayalakshmi Ayyar

  14. Development of humanized scFv antibody fragment(s) that targets and blocks specific HLA alleles linked to myasthenia gravis

    Article • Applied Microbiology and Biotechnology, October 2017, Springer Science + Business Media

    Dr B Vijayalakshmi Ayyar

  15. Affinity chromatography: A versatile technique for antibody purification

    Article • Methods, March 2017, Elsevier

    Dr Sushrut Arora, Dr B Vijayalakshmi Ayyar

  16. Optimizing antibody expression: The nuts and bolts

    Article • Methods, March 2017, Elsevier

    Dr B Vijayalakshmi Ayyar, Dr Sushrut Arora

  17. Coming-of-Age of Antibodies in Cancer Therapeutics

    Article • Trends in Pharmacological Sciences, December 2016, Elsevier

    Dr B Vijayalakshmi Ayyar, Dr Sushrut Arora

  18. Effects of membrane properties on the binding activities of the HN and HC heavy-chain domains of botulinum neurotoxin A

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, September 2016, Elsevier

    Dr B Vijayalakshmi Ayyar

  19. Antigenic sites on the HN domain of botulinum neurotoxin A stimulate protective antibody responses against active toxin

    Article • Scientific Reports, October 2015, Nature

    Dr B Vijayalakshmi Ayyar

  20. The C-Terminal Heavy-Chain Domain of Botulinum Neurotoxin A Is Not the Only Site That Binds Neurons, as the N-Terminal Heavy-Chain Domain Also Plays a Very Active Role in Toxin-Cell Binding and Interactions

    Article • Infection and Immunity, January 2015, ASM Journals

    Dr B Vijayalakshmi Ayyar

  21. Facile domain rearrangement abrogates expression recalcitrance in a rabbit scFv

    Article • Applied Microbiology and Biotechnology, December 2014, Springer Science + Business Media

    Dr B Vijayalakshmi Ayyar

  22. Affinity Chromatography for Antibody Purification

    Article • January 2014, Springer Science + Business Media

    Dr Sushrut Arora, Dr B Vijayalakshmi Ayyar

  23. Affinity chromatography as a tool for antibody purification

    Article • Methods, February 2012, Elsevier

    Dr Sushrut Arora, Dr B Vijayalakshmi Ayyar

  24. Highly sensitive recombinant antibodies capable of reliably differentiating heart-type fatty acid binding protein from noncardiac isoforms

    Article • Analytical Biochemistry, December 2010, Elsevier

    Dr B Vijayalakshmi Ayyar

  25. Surface plasmon resonance for vaccine design and efficacy studies: recent applications and future trends

    Article • Expert Review of Vaccines, June 2010, Taylor & Francis

    Dr B Vijayalakshmi Ayyar