All Stories

  1. Synthesis, Characterization of Novel Morpholino-1, 3, 5-Triazinyl Amino Acid Ester Derivatives and their Anti-Proliferation Activities

    Article • Letters in Organic Chemistry, November 2015, Bentham Science Publishers

    Professor Ayman A. El-Faham

  2. Production and physicochemical assessment of new stevia amino acid sweeteners from the natural stevioside

    Article • Food Chemistry, April 2015, Elsevier

    Professor Ayman A. El-Faham

  3. Methods for the Peptide Synthesis and Analysis

    Article • February 2015, Wiley

    Professor Ayman A. El-Faham

  4. Peptide synthesis beyond DMF: THF and ACN as excellent and friendlier alternatives

    Article • Organic & Biomolecular Chemistry, January 2015, Royal Society of Chemistry

    Professor Ayman A. El-Faham

  5. TOMBU and COMBU as Novel Uronium-Type Peptide Coupling Reagents Derived from Oxyma-B

    Article • Molecules, November 2014, MDPI AG

    Professor Ayman A. El-Faham

  6. ChemInform Abstract: Advances in Acylation Methodologies Enabled by Oxyma-Based Reagents

    Article • ChemInform, October 2014, Wiley

    Professor Ayman A. El-Faham

  7. Low-epimerization Peptide Bond Formation with Oxyma Pure: Preparation of Z-L-Phg-Val-OMe

    Article • April 2014, Wiley

    Professor Ayman A. El-Faham

  8. Organophosphinic Coupling Reagents in Peptide Synthesis

    Article • February 2014, Global Science & Technology Forum

    Professor Ayman A. El-Faham

  9. Synthesis, Characterization and Anti-proliferation Activities of Novel Cyano Oximino Sulfonate Esters

    Article • Chemical and Pharmaceutical Bulletin, January 2014, Pharmaceutical Society of Japan

    Professor Ayman A. El-Faham

  10. OxymaPure/DIC: An Efficient Reagent for the Synthesis of a Novel Series of 4-[2-(2-Acetylaminophenyl)-2-oxo-acetylamino] Benzoyl Amino Acid Ester Derivatives

    Article • Molecules, November 2013, MDPI AG

    Professor Ayman A. El-Faham

  11. K-Oxyma: a Strong Acylation-Promoting, 2-CTC Resin-Friendly Coupling Additive

    Article • European Journal of Organic Chemistry, August 2013, Wiley

    Professor Ayman A. El-Faham

  12. Synthesis, structure, theoretical calculations and biological activity of sulfonate active ester new derivatives

    Article • Journal of Molecular Structure, August 2013, Elsevier

    Professor Ayman A. El-Faham

  13. An Efficient and Mild Method for the Synthesis and Hydrazinolysis ofN-Glyoxylamino Acid Esters

    Article • Journal of Chemistry, January 2013, Hindawi Publishing Corporation

    Professor Ayman A. El-Faham, Professor M Rafiq H Siddiqui

  14. Oxime-Based Carbonates as Useful Reagents for Both N-Protection and Peptide Coupling

    Article • Molecules, December 2012, MDPI AG

    Professor Ayman A. El-Faham

  15. Synthesis and characterization of new polyamides derived from alanine and valine derivatives

    Article • Chemistry Central Journal, November 2012, Springer Science + Business Media

    Professor Ayman A. El-Faham

  16. Microwave synthesis and thermal properties of polyacrylate derivatives containing itaconic anhydride moieties

    Article • Chemistry Central Journal, August 2012, Springer Science + Business Media

    Professor Ayman A. El-Faham

  17. Microwave irradiation: A facile, scalable and convenient method for synthesis of N-phthaloylamino acids

    Article • Arabian Journal of Chemistry, July 2012, Elsevier

    Professor Ayman A. El-Faham

  18. Screening ofN-Alkyl-Cyanoacetamido Oximes as Substitutes forN-Hydroxysuccinimide

    Article • ChemistryOpen, June 2012, Wiley

    Professor Ayman A. El-Faham

  19. ChemInform Abstract: Peptide-Coupling Reagents

    Article • ChemInform, May 2012, Wiley

    Professor Ayman A. El-Faham

  20. Cyanoacetamide-based oxime carbonates: an efficient, simple alternative for the introduction of Fmoc with minimal dipeptide formation

    Article • Tetrahedron, April 2012, Elsevier

    Professor Ayman A. El-Faham

  21. Recent development in peptide coupling reagents

    Article • Journal of Saudi Chemical Society, April 2012, Elsevier

    Professor Ayman A. El-Faham

  22. ChemInform Abstract: Aspartimide Formation in Peptide Chemistry: Occurrence, Prevention Strategies and the Role of N-Hydroxylamines

    Article • ChemInform, February 2012, Wiley

    Professor Ayman A. El-Faham

  23. Synthesis and Thermal Properties of Novel Polyamides Containing α-Amino Acid Moieties: Structure-Property Relationship

    Article • Journal of Macromolecular Science Part A, January 2012, Taylor & Francis

    Professor Ayman A. El-Faham

  24. ChemInform Abstract: Peptide Coupling Reagents - More than a Letter Soup

    Article • ChemInform, December 2011, Wiley

    Professor Ayman A. El-Faham

  25. Peptide Coupling Reagents, More than a Letter Soup

    Article • Chemical Reviews, November 2011, American Chemical Society (ACS)

    Professor Ayman A. El-Faham

  26. Aspartimide formation in peptide chemistry: occurrence, prevention strategies and the role of N-hydroxylamines

    Article • Tetrahedron, November 2011, Elsevier

    Professor Ayman A. El-Faham

  27. Peptide-Coupling Reagents

    Article • January 2011, Wiley

    Professor Ayman A. El-Faham

  28. Synthesis and Aminolysis of 2,4-Dinitrophenyl and 5-Nitropyridine N-Hydroxy Oxime Derivatives

    Article • Bulletin of the Chemical Society of Japan, January 2011, Chemical Society of Japan

    Professor Ayman A. El-Faham

  29. Synthesis of 2-(4,6-Dimethoxy-1,3,5-triazin-2-yloxyimino) Derivatives: Application in Solution Peptide Synthesis

    Article • Molecules, December 2010, MDPI AG

    Professor Ayman A. El-Faham

  30. N-Hydroxylamines for Peptide Synthesis

    Article • November 2010, Wiley

    Professor Ayman A. El-Faham

  31. ChemInform Abstract: The 1,1-Dioxobenzo[b]thiophene-2-ylmethyloxycarbonyl (Bsmoc) Amino-Protecting Group.

    Article • ChemInform, June 2010, Wiley

    Professor Ayman A. El-Faham

  32. ChemInform Abstract: The Solid State and Solution Structure of HAPyU (I).

    Article • ChemInform, May 2010, Wiley

    Professor Ayman A. El-Faham

  33. A Novel Family of Onium Salts Based Upon Isonitroso Meldrum's Acid Proves Useful as Peptide Coupling Reagents

    Article • European Journal of Organic Chemistry, May 2010, Wiley

    Professor Ayman A. El-Faham

  34. PyOxP and PyOxB: the Oxyma-based novel family of phosphonium salts

    Article • Organic & Biomolecular Chemistry, January 2010, Royal Society of Chemistry

    Professor Ayman A. El-Faham

  35. COMU: A third generation of uronium-type coupling reagents

    Article • Journal of Peptide Science, January 2010, Wiley

    Professor Ayman A. El-Faham

  36. Microwave irradiation and COMU: a potent combination for solid-phase peptide synthesis

    Article • Tetrahedron Letters, November 2009, Elsevier

    Professor Ayman A. El-Faham

  37. COMU: A Safer and More Effective Replacement for Benzotriazole-Based Uronium Coupling Reagents

    Article • Chemistry - A European Journal, September 2009, Wiley

    Professor Ayman A. El-Faham

  38. Dicyclopropylmethyl Peptide Backbone Protectant †

    Article • Organic Letters, August 2009, American Chemical Society (ACS)

    Professor Ayman A. El-Faham

  39. ChemInform Abstract: Utilization of N,N,N′,N′-Tetramethylfluoroformamidinium Hexafluorophosphate (TFFH) in Peptide and Organic Synthesis

    Article • ChemInform, July 2009, Wiley

    Professor Ayman A. El-Faham

  40. Synthesis and Application ofN-Hydroxylamine Derivatives as Potential Replacements for HOBt

    Article • European Journal of Organic Chemistry, April 2009, Wiley

    Professor Ayman A. El-Faham

  41. Utilization of N,N,N′,N′-Tetramethylfluoroformamidinium Hexafluoro­phosphate (TFFH) in Peptide and Organic Synthesis

    Article • Synlett, March 2009, Thieme Publishing Group

    Professor Ayman A. El-Faham

  42. Use ofN‐Methylpiperazine for the Preparation of Piperazine‐Based Unsymmetrical Bis‐Ureas as Anti‐HIV Agents

    Article • ChemMedChem, July 2008, Wiley

    Professor Ayman A. El-Faham

  43. Morpholine-Based Immonium and Halogenoamidinium Salts as Coupling Reagents in Peptide Synthesis1

    Article • The Journal of Organic Chemistry, April 2008, American Chemical Society (ACS)

    Professor Ayman A. El-Faham

  44. 1,1,3,3-Tetramethylfluoroformamidinium Hexafluorophosphate

    Article • March 2008, Wiley

    Professor Ayman A. El-Faham

  45. Novel Proton Acceptor Immonium-Type Coupling Reagents:  Application in Solution and Solid-Phase Peptide Synthesis

    Article • Organic Letters, October 2007, American Chemical Society (ACS)

    Professor Ayman A. El-Faham

  46. Reaction of Phthalaldehydic Acid with Different Substituted Aniline as well as Hydrazine Derivatives.

    Article • ChemInform, September 2007, Wiley

    Professor Ayman A. El-Faham

  47. Reaction of phthalaldehydic acid with different substituted aniline as well as hydrazine derivatives

    Article • Journal of Heterocyclic Chemistry, May 2007, Wiley

    Professor Ayman A. El-Faham

  48. Chloroformamidinium Salts: Efficient Reagents for Preparation of 2-Aminobenzoimidazole, 2-Aminobenzoxazole, and 2-Aminobenzothiazole Derivatives.

    Article • ChemInform, October 2006, Wiley

    Professor Ayman A. El-Faham

  49. Tetramethylfluoroformamidinium hexafluorophosphate (TFFH)/benzyltriphenylphosphonium dihydrogen trifluoride (PTF): a unique reagent for the conversion of carboxylic acids to the corresponding alcohols as well as hydroxamic acids

    Article • ARKIVOC, August 2006, University of Michigan Library

    Professor Ayman A. El-Faham

  50. Chloroformamidinium salts: Efficient reagents for preparation of 2-aminobenzoimidazole, 2-aminobenzoxazole, and 2-aminobenzothiazole derivatives

    Article • Journal of Heterocyclic Chemistry, May 2006, Wiley

    Professor Ayman A. El-Faham

  51. Design and Synthesis of New Immonium-Type Coupling Reagents

    Article • European Journal of Organic Chemistry, March 2006, Wiley

    Professor Ayman A. El-Faham

  52. Coupling Reactions of Hydralazine with Amino Acids and Their Adducts for Antihypertensive Activities.

    Article • ChemInform, October 2004, Wiley

    Professor Ayman A. El-Faham

  53. Coupling reactions of hydralazine with amino acids and their adducts for antihypertensive activities

    Article • Journal of Heterocyclic Chemistry, May 2004, Wiley

    Professor Ayman A. El-Faham

  54. Organophosphorus and Nitro-Substituted Sulfonate Esters of 1-Hydroxy-7-azabenzotriazole as Highly Efficient Fast-Acting Peptide Coupling Reagents.

    Article • ChemInform, April 2004, Wiley

    Professor Ayman A. El-Faham

  55. 3-Hydroxy-4-oxo-3,4-dihydro-5-azabenzo-1,2,3-triazene†

    Article • The Journal of Organic Chemistry, January 2004, American Chemical Society (ACS)

    Professor Ayman A. El-Faham

  56. 1,1,3,3-Tetramethylfluoroformamidinium Hexafluorophosphate

    Article • April 2003, Wiley

    Professor Ayman A. El-Faham

  57. O-(7-Azabenzotriazol-1-yl)-1,3-dimethyl- 1,3-dimethyleneuronium Hexafluorophos-phate

    Article • April 2003, Wiley

    Professor Ayman A. El-Faham

  58. Complex Polyfluoride Additives in Fmoc-Amino Acid Fluoride Coupling Processes. Enhanced Reactivity and Avoidance of Stereomutation †

    Article • Organic Letters, April 2003, American Chemical Society (ACS)

    Professor Ayman A. El-Faham

  59. Kupplungsreagentien vom Uronium-/Guanidinium-Typ: Synthese und Charakterisierung der authentischen Uroniumsalze

    Article • Angewandte Chemie, February 2002, Wiley

    Professor Ayman A. El-Faham

  60. A versatile synthetic route to chiral quinoxaline derivatives from amino acids precursors

    Article • January 2002, Springer Science + Business Media

    Professor Ayman A. El-Faham

  61. Substituted Guanidines:  Introducing Diversity in Combinatorial Chemistry

    Article • Organic Letters, November 2000, American Chemical Society (ACS)

    Professor Ayman A. El-Faham

  62. Addition of HOXt (X = A or B) improves the efficiency of phenol-based coupling reagents during peptide synthesis

    Article • March 2000, Springer Science + Business Media

    Professor Ayman A. El-Faham

  63. The 1,1-Dioxobenzo[ b ]thiophene-2-ylmethyloxycarbonyl (Bsmoc) † Amino-Protecting Group

    Article • The Journal of Organic Chemistry, June 1999, American Chemical Society (ACS)

    Professor Ayman A. El-Faham

  64. The diisopropylcarbodiimide/ 1-hydroxy-7-azabenzotriazole system: Segment coupling and stepwise peptide assembly

    Article • Tetrahedron, May 1999, Elsevier

    Professor Ayman A. El-Faham

  65. Use of Onium Salt-Based Coupling Reagents in Peptide Synthesis 1

    Article • The Journal of Organic Chemistry, December 1998, American Chemical Society (ACS)

    Professor Ayman A. El-Faham

  66. Bis(tetramethylene)fluoroformamidinium Hexafluorophospnate(BTFFH): A Convenient Coupling Reagent for Solid Phase Peptide Synthesis.

    Article • Chemistry Letters, January 1998, Chemical Society of Japan

    Professor Ayman A. El-Faham

  67. Protected amino acid chlorides vs protected amino acid fluorides: Reactivity comparisons

    Article • Tetrahedron Letters, January 1998, Elsevier

    Professor Ayman A. El-Faham

  68. Spectral Characterization of Some Phenylazodihydroxy Naphthalene Derivatives

    Article • Spectroscopy Letters, September 1996, Taylor & Francis

    Professor Ayman A. El-Faham

  69. Peptide Coupling in the Presence of Highly Hindered Tertiary Amines

    Article • The Journal of Organic Chemistry, January 1996, American Chemical Society (ACS)

    Professor Ayman A. El-Faham

  70. Efficiency in Peptide Coupling: 1-Hydroxy-7-azabenzotriazole vs 3,4-Dihydro-3-hydroxy-4-oxo-1,2,3-benzotriazine

    Article • The Journal of Organic Chemistry, June 1995, American Chemical Society (ACS)

    Professor Ayman A. El-Faham

  71. Tetramethylfluoroformamidinium Hexafluorophosphate: A Rapid-Acting Peptide Coupling Reagent for Solution and Solid Phase Peptide Synthesis

    Article • Journal of the American Chemical Society, May 1995, American Chemical Society (ACS)

    Professor Ayman A. El-Faham

  72. Peptide assembly in the absence of base via Fmoc amino acid fluorides

    Article • Journal of the Chemical Society Chemical Communications, January 1995, Royal Society of Chemistry

    Professor Ayman A. El-Faham

  73. Racemization studies during solid-phase peptide synthesis using azabenzotriazole-based coupling reagents

    Article • Tetrahedron Letters, April 1994, Elsevier

    Professor Ayman A. El-Faham

  74. Effect of Tertiary Bases on O-Benzotriazolyluronium Salt-Induced Peptide Segment Coupling

    Article • The Journal of Organic Chemistry, February 1994, American Chemical Society (ACS)

    Professor Ayman A. El-Faham

  75. Advantageous applications of azabenzotriazole (triazolopyridine)-based coupling reagents to solid-phase peptide synthesis

    Article • Journal of the Chemical Society Chemical Communications, January 1994, Royal Society of Chemistry

    Professor Ayman A. El-Faham

  76. Bis(BOC) amino acid fluorides as reactive peptide coupling reagents

    Article • The Journal of Organic Chemistry, July 1993, American Chemical Society (ACS)

    Professor Ayman A. El-Faham

  77. Protected amino acid chlorides: Coupling reagents suitable for the most highly hindered systems

    Article • Springer Science + Business Media

    Professor Ayman A. El-Faham