All Stories

  1. Expanding the results of a high throughput screen against an isochorismate-pyruvate lyase to enzymes of a similar scaffold or mechanism

    Article • Bioorganic & Medicinal Chemistry, November 2014, Elsevier

    Professor Audrey Lamb

  2. Structure of anAspergillus fumigatusold yellow enzyme (EasA) involved in ergot alkaloid biosynthesis

    Article • Acta Crystallographica Section F Structural Biology Communications, September 2014, International Union of Crystallography

    Professor Audrey Lamb

  3. Compensating for the Absence of Selenocysteine in High-Molecular Weight Thioredoxin Reductases: The Electrophilic Activation Hypothesis

    Article • Biochemistry, January 2014, American Chemical Society (ACS)

    Professor Audrey Lamb

  4. Redesign of MST enzymes to target lyase activity instead promotes mutase and dehydratase activities

    Article • Archives of Biochemistry and Biophysics, November 2013, Elsevier

    Professor Audrey Lamb

  5. Lysine221 is the general base residue of the isochorismate synthase from Pseudomonas aeruginosa (PchA) in a reaction that is diffusion limited

    Article • Archives of Biochemistry and Biophysics, October 2013, Elsevier

    Professor Audrey Lamb

  6. Two Structures of a Thiazolinyl Imine Reductase from Yersinia enterocolitica Provide Insight into Catalysis and Binding to the Nonribosomal Peptide Synthetase Module of HMWP1

    Article • Biochemistry, October 2012, American Chemical Society (ACS)

    Professor Audrey Lamb

  7. Modification of Residue 42 of the Active Site Loop with a Lysine-Mimetic Side Chain Rescues Isochorismate-Pyruvate Lyase Activity in Pseudomonas aeruginosa PchB

    Article • Biochemistry, September 2012, American Chemical Society (ACS)

    Professor Audrey Lamb

  8. Mechanistic and structural studies of the N-hydroxylating flavoprotein monooxygenases

    Article • Bioorganic Chemistry, December 2011, Elsevier

    Professor Audrey Lamb

  9. Pericyclic Reactions Catalyzed by Chorismate-Utilizing Enzymes

    Article • Biochemistry, August 2011, American Chemical Society (ACS)

    Professor Audrey Lamb

  10. pH Dependence of Catalysis by Pseudomonas aeruginosa Isochorismate–Pyruvate Lyase: Implications for Transition State Stabilization and the Role of Lysine 42

    Article • Biochemistry, July 2011, American Chemical Society (ACS)

    Professor Audrey Lamb

  11. Entropic and Enthalpic Components of Catalysis in the Mutase and Lyase Activities of Pseudomonas aeruginosa PchB

    Article • Journal of the American Chemical Society, April 2011, American Chemical Society (ACS)

    Professor Audrey Lamb

  12. Structure ofEscherichia colimalate dehydrogenase at 1.45 Å resolution

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, August 2009, International Union of Crystallography

    Professor Audrey Lamb

  13. Expression, purification, crystallization and preliminary X-ray analysis of the DNA-binding domain of aChlamydia trachomatisOmpR/PhoB-subfamily response regulator homolog, ChxR

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, July 2009, International Union of Crystallography

    Professor Audrey Lamb

  14. Structure−Function Analyses of Isochorismate-Pyruvate Lyase from Pseudomonas aeruginosa Suggest Differing Catalytic Mechanisms for the Two Pericyclic Reactions of This Bifunctional Enzyme

    Article • Biochemistry, May 2009, American Chemical Society (ACS)

    Professor Audrey Lamb

  15. Kinetic Mechanism of Ornithine Hydroxylase (PvdA) from Pseudomonas aeruginosa: Substrate Triggering of O2 Addition but Not Flavin Reduction

    Article • Biochemistry, April 2009, American Chemical Society (ACS)

    Professor Audrey Lamb

  16. Biochemical Characterization of a Flavin Adenine Dinculeotide-Dependent Monooxygenase, Ornithine Hydroxylase fromPseudomonas aeruginosa, Suggests a Novel Reaction Mechanism

    Article • Biochemistry, September 2007, American Chemical Society (ACS)

    Professor Audrey Lamb

  17. Heterodimer Formation between Superoxide Dismutase and Its Copper Chaperone

    Article • Biochemistry, November 2000, American Chemical Society (ACS)

    Professor Audrey Lamb

  18. Crystal Structure of the Second Domain of the Human Copper Chaperone for Superoxide Dismutase,

    Article • Biochemistry, January 2000, American Chemical Society (ACS)

    Professor Audrey Lamb

  19. The Structure of Retinal Dehydrogenase Type II at 2.7 Å Resolution:  Implications for Retinal Specificity,

    Article • Biochemistry, April 1999, American Chemical Society (ACS)

    Professor Audrey Lamb

  20. Purification, crystallization and preliminary X-ray diffraction studies of retinal dehydrogenase type II

    Article • Acta Crystallographica Section D Biological Crystallography, July 1998, International Union of Crystallography

    Professor Audrey Lamb