All Stories

  1. Biophysical insights into protein–co-solute interactions of alpha lactalbumin: mitigating urea effects in physiological crowded environments
  2. Insight into the Interaction and Inhibition of NS3 ATPase of Dengue Virus with 3′-Azido-3′-deoxythymidine: Computational and Biophysical Approaches
  3. Urea induced characterization & structural dynamics of the Nucleocapsid Protein using biophysical and in silico approaches
  4. Insights into Mechanism of Ionic Liquids for Protein Stability: Future Implications for Neurodegeneration Treatment
  5. Exploring the binding energies of new pyrazoline derivatives to DNA/BSA: antifungal, antioxidant, MD simulations and TD-DFT studies
  6. Antibacterial potential of Trichoderma bioactive metabolites in managing Staphylococcus aureus infection: Integrated molecular modeling approaches
  7. Computational evaluation of Jeevamrutha metabolites binding affinity to MurE enzyme of Xanthomonas oryzae pv. oryzae for bacterial disease management
  8. Targeting rice blast disease: evaluating binding affinity of trichoderma metabolite to Pyricularia oryzae GSK-1 through molecular modeling approaches
  9. Identification of high-affinity inhibitors for epoxide hydrolase 2 from repurposed drugs in Parkinson’s disease therapeutics
  10. Delineating the Mechanistic Insight of Inhibition of α-Synuclein Fibrillation by Neuro Metabolite, Myo-inositol: Implications in Synucleopathies-Related Disorders
  11. Biochemical Screening of Phytochemicals and Identification of Scopoletin as a Potential Inhibitor of SARS-CoV-2 Mpro, Revealing Its Biophysical Impact on Structural Stability
  12. Telomeric RNA quadruplexes as targets for cancer prevention: The therapeutic potential of agonodepsides
  13. Targeting tau in Alzheimer’s and beyond: Insights into pathology and therapeutic strategies
  14. pH induced structural and conformational changes in nucleocapsid protein leads to intermediate like conformation: a biophysical and computational approach
  15. Understanding the role of potential biomarkers in attenuating multiple sclerosis progression via multiomics and network-based approach
  16. Navigating the Maze of Alzheimer’s disease by exploring BACE1: Discovery, current scenario, and future prospects
  17. Amyloid-induced neurodegeneration: A comprehensive review through aggregomics perception of proteins in health and pathology
  18. Understanding the Modulation of α-Synuclein Fibrillation by N-Acetyl Aspartate: A Brain Metabolite
  19. Comprehensive Perspective Towards the Management of Proteinopathies by Elucidating Protein Misfolding and Aggregation
  20. Elucidating the pH-dependent conformational transitions of eryngin: Insights from molecular dynamics simulations
  21. The Molecular Blueprint for Chronic Obstructive Pulmonary Disease (COPD): A New Paradigm for Diagnosis and Therapeutics
  22. Integrated spectroscopic and MD simulation approach to decipher the effect of pH on the structure function of Staphylococcus aureus thymidine kinase
  23. Polyherbal nano formulation: A potent antibiotic resistance breaker in bovine mastitis causing MDR pathogens
  24. Recent advancement in therapeutic strategies for Alzheimer’s disease: Insights from clinical trials
  25. Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative Diseases
  26. Interaction studies of recombinant laccase with co-solutes: Using various spectroscopic, calorimetric, and in silico approaches
  27. Role of sugar osmolytes and their nano-counterparts as inhibitors in protein fibrillation
  28. Therapeutic targeting of microtubule affinity‐regulating kinase 4 in cancer and neurodegenerative diseases
  29. Laccase Engineering: Redox Potential Is Not the Only Activity-Determining Feature in the Metalloproteins
  30. Polyethylene glycol induced structural modulation of holo alpha-lactalbumin: In vitro and in vivo approach towards protein stability
  31. Aggregation of irisin and its prevention by trehalose: A biophysical approach
  32. Nature's toolbox against tau aggregation: An updated review of current research
  33. Signature Garlic Phytochemical as a Potential Anti-Candidal Candidate Targeting Virulence Factors in Candida albicans 
  34. Counteraction of the cetyltrimethylammonium bromide-induced protein aggregation by heparin: Potential impact on protein aggregation and neurodegenerative diseases using biophysical approaches
  35. Interaction of Thioflavin T (ThT) and 8-anilino-1-naphthalene sulfonic acid (ANS) with macromolecular crowding agents and their monomers: Biophysical analysis using in vitro and computational approaches
  36. Elucidating the Role of Santalol as a Potent Inhibitor of Tyrosinase: In Vitro and In Silico Approaches
  37. Characterization of advanced glycation end products and aggregates of irisin: Multispectroscopic and microscopic approaches
  38. Mitochondrial Dysfunction: Pathophysiology and Mitochondria-Targeted Drug Delivery Approaches
  39. Identification of Thermostable Xylose Reductase fromThermothelomyces thermophilus: A Biochemical Characterization Approach to Meet Biofuel Challenges
  40. Measuring Structural Changes in Cytochrome c under Crowded Conditions Using In Vitro and In Silico Approaches
  41. Elucidating the Role of Santalol as A Potent Inhibitor of Tyrosinase: <em>In Vitro</em> and <em>In Silico</em> Approaches
  42. Interferons Horizon Therapeutics
  43. Mechanistic Insight into the Enzymatic Inhibition of β-Amyrin against Mycobacterial Rv1636: In Silico and In Vitro Approaches
  44. Design and evaluation of pyrimidine derivatives as potent inhibitors of ABCG2, a breast cancer resistance protein
  45. Inhibiting Cyclin-Dependent Kinase 6 by Taurine: Implications in Anticancer Therapeutics
  46. Investigating binding mechanism of thymoquinone to human transferrin, targeting Alzheimer's disease therapy
  47. Phytochemicals targeting NF-κB signaling: Potential anti-cancer interventions
  48. Unraveling the Binding Mechanism of Alzheimer’s Drugs with Irisin: Spectroscopic, Calorimetric, and Computational Approaches
  49. Insights into Fluctuations of Structure of Proteins: Significance of Intermediary States in Regulating Biological Functions
  50. Insights into the Antibacterial Activity of Prolactin-Inducible Protein against the Standard and Environmental MDR Bacterial Strains
  51. Mutation in the CX3C Motif of G Protein Disrupts Its Interaction with Heparan Sulfate: A Calorimetric, Spectroscopic, and Molecular Docking Study
  52. FNDC5/Irisin: Physiology and Pathophysiology
  53. Parkinson’s Disease: A Current Perspectives on Parkinson’s Disease and Key Bioactive Natural Compounds as Future Potential Drug Candidates
  54. Structural Characterization of Ectodomain G Protein of Respiratory Syncytial Virus and Its Interaction with Heparan Sulfate: Multi-Spectroscopic and In Silico Studies Elucidating Host-Pathogen Interactions
  55. Delineating the Aggregation-Prone Hotspot Regions (Peptides) in the Human Cu/Zn Superoxide Dismutase 1
  56. Therapeutic Potential of Ursolic Acid in Cancer and Diabetic Neuropathy Diseases
  57. Myricetin inhibits breast and lung cancer cells proliferation via inhibiting MARK4
  58. Characterization of different intermediate states in myoglobin induced by polyethylene glycol: A process of spontaneous molecular self-organization foresees the energy landscape theory via in vitro and in silico approaches
  59. Investigating single amino acid substitutions in PIM1 kinase: A structural genomics approach
  60. MAP/Microtubule Affinity Regulating Kinase 4 Inhibitory Potential of Irisin: A New Therapeutic Strategy to Combat Cancer and Alzheimer’s Disease
  61. An Insight Into Mitochondrial Dysfunction and its Implications in Neurological Diseases
  62. Impact of single amino acid substitution on the structure and function of TANK‐binding kinase‐1
  63. Structure‐based investigation of MARK4 inhibitory potential of Naringenin for therapeutic management of cancer and neurodegenerative diseases
  64. Structural Refolding and Thermal Stability of Myoglobin in the Presence of Mixture of Crowders: Importance of Various Interactions for Protein Stabilization in Crowded Conditions
  65. Targeting the Sphingosine Kinase/Sphingosine-1-Phosphate Signaling Axis in Drug Discovery for Cancer Therapy
  66. Structural Characterization and Binding Studies of the Ectodomain G Protein of Respiratory Syncytial Virus Reveal the Crucial Role of pH with Possible Implications in Host–Pathogen Interactions
  67. Glossary of phytoconstituents: Can these be repurposed against SARS CoV-2? A quick in silico screening of various phytoconstituents from plant Glycyrrhiza glabra with SARS CoV-2 main protease
  68. Elucidating the Interaction of Human Ferritin with Quercetin and Naringenin: Implication of Natural Products in Neurodegenerative Diseases: Molecular Docking and Dynamics Simulation Insight
  69. Trehalose Restrains the Fibril Load towards α-Lactalbumin Aggregation and Halts Fibrillation in a Concentration-Dependent Manner
  70. Multispectroscopic and Molecular Docking Insight into Elucidating the Interaction of Irisin with Rivastigmine Tartrate: A Combinational Therapy Approach to Fight Alzheimer’s Disease
  71. Morphology, Genomic Organization, Proteins and Replication of SARS-CoV-2
  72. Effect of Antioxidants on Heavy Metals Induced Conformational Alteration of Cytochrome C and Myoglobin
  73. Heparin Accelerates the Protein Aggregation via the Downhill Polymerization Mechanism: Multi-Spectroscopic Studies to Delineate the Implications on Proteinopathies
  74. Insight into the binding of PEG-400 with eye protein alpha-crystallin: Multi spectroscopic and computational approach: possible therapeutics targeting eye diseases
  75. Heme-iron ligand (M80-Fe) in cytochrome c is destabilizing: combined in vitro and in silico approaches to monitor changes in structure, stability and dynamics of the protein on mutation
  76. Concentration dependent effect of ethylene glycol on the structure and stability of holo α-lactalbumin: Characterization of intermediate state amidst soft interactions
  77. Conformational changes in cytochrome c directed by ethylene glycol accompanying complex formation: Protein-solvent preferential interaction or/and kosmotropic effect
  78. Evaluation of Binding of Rosmarinic Acid with Human Transferrin and Its Impact on the Protein Structure: Targeting Polyphenolic Acid-Induced Protection of Neurodegenerative Disorders
  79. Inhibiting CDK6 Activity by Quercetin Is an Attractive Strategy for Cancer Therapy
  80. Biophysical Elucidation of Fibrillation Inhibition by Sugar Osmolytes in α-Lactalbumin: Multispectroscopic and Molecular Docking Approaches
  81. Corona virus versus existence of human on the earth: A computational and biophysical approach
  82. Identification of high-affinity inhibitors of SARS-CoV-2 main protease: Towards the development of effective COVID-19 therapy
  83. Structural and biochemical investigation of MARK4 inhibitory potential of cholic acid: Towards therapeutic implications in neurodegenerative diseases
  84. A Systems View of the Genome Guardians: Mapping the Signaling Circuitry Underlying Oligonucleotide/Oligosaccharide-Binding Fold Proteins
  85. Effects of natural mutations (L94I and L94V) on the stability and mechanism of folding of horse cytochrome c: A combined in vitro and molecular dynamics simulations approach
  86. Biophysical Insights into Implications of PEG-400 on the α-Crystallin Structure: Multispectroscopic and Microscopic Approach
  87. Identification of Potential Inhibitors of Calcium/Calmodulin-Dependent Protein Kinase IV from Bioactive Phytoconstituents
  88. Unravelling the unfolding pathway of human Fas-activated serine/threonine kinase induced by urea
  89. Rosmarinic Acid Exhibits Anticancer Effects via MARK4 Inhibition
  90. Effects of Ethylene Glycol on the Structure and Stability of Myoglobin Using Spectroscopic, Interaction, and In Silico Approaches: Monomer Is Different from Those of Its Polymers
  91. Glecaprevir and Maraviroc are high-affinity inhibitors of SARS-CoV-2 main protease: possible implication in COVID-19 therapy
  92. MARK4 Inhibited by AChE Inhibitors, Donepezil and Rivastigmine Tartrate: Insights into Alzheimer’s Disease Therapy
  93. Ellagic Acid Controls Cell Proliferation and Induces Apoptosis in Breast Cancer Cells via Inhibition of Cyclin-Dependent Kinase 6
  94. Structure, function and therapeutic implications of OB-fold proteins: A lesson from past to present
  95. Molecular and macromolecular crowding-induced stabilization of proteins: Effect of dextran and its building block alone and their mixtures on stability and structure of lysozyme
  96. Urea Stress: Myo-inositol's efficacy to counteract destabilization of TIM-β-globin complex by urea is as good as that of the methylamine
  97. Formation of molten globule state in horse heart cytochrome c under physiological conditions: Importance of soft interactions and spectroscopic approach in crowded milieu
  98. Optimization of Parameters for Expression and Purification of G Glycoprotein Ectodomain of Respiratory Syncytial Virus
  99. Probing the interaction of Rivastigmine Tartrate, an important Alzheimer's drug, with serum albumin: Attempting treatment of Alzheimer's disease
  100. The anti-oxidant enzyme, Prdx6 might have cis-acting regulatory sequence(s)
  101. Interactions Under Crowding Milieu: Chemical-Induced Denaturation of Myoglobin is Determined by the Extent of Heme Dissociation on Interaction with Crowders
  102. Investigation of guanidinium chloride-induced unfolding pathway of sphingosine kinase 1
  103. Effect of pH on the structure and function of pyruvate dehydrogenase kinase 3: Combined spectroscopic and MD simulation studies
  104. Virtual Screening Approach to Identify High-Affinity Inhibitors of Serum and Glucocorticoid-Regulated Kinase 1 among Bioactive Natural Products: Combined Molecular Docking and Simulation Studies
  105. Structural Features of Nucleoprotein CST/Shelterin Complex Involved in the Telomere Maintenance and Its Association with Disease Mutations
  106. Amphiphilic nature of polyethylene glycols and their role in medical research
  107. Identification of high-affinity inhibitors of pyruvate dehydrogenase kinase-3: towards therapeutic management of cancer
  108. Targeting metacaspase-3 from Plasmodium falciparum towards antimalarial therapy: A combined approach of in-silico and in-vitro investigation
  109. Discovery of 4-(2-(dimethylamino)ethoxy)benzohydrazide derivatives as prospective microtubule affinity regulating kinase 4 inhibitors
  110. Molecular basis of pathogenic parasitic infections insights from parasite kinome
  111. Investigation of conformational dynamics of Tyr89Cys mutation in protection of telomeres 1 gene associated with familial melanoma
  112. Ionic Liquid Green Assembly-Mediated Migration of Piperine from Calf-Thymus DNA: A New Possibility of the Tunable Drug Delivery System
  113. Backbone and side chain 1H, 15N and 13C chemical shift assignments of the molten globule state of L94G mutant of horse cytochrome-c
  114. Virtual high-throughput screening of natural compounds in-search of potential inhibitors for protection of telomeres 1 (POT1)
  115. Exploration of Fungal Lipase as Direct Target of Eugenol through Spectroscopic Techniques
  116. Evaluation of pyrazolopyrimidine derivatives as microtubule affinity regulating kinase 4 inhibitors: Towards therapeutic management of Alzheimer’s disease
  117. Unraveling Binding Mechanism of Alzheimer’s Drug Rivastigmine Tartrate with Human Transferrin: Molecular Docking and Multi-Spectroscopic Approach towards Neurodegenerative Diseases
  118. Carbohydrate-Based Macromolecular Crowding-Induced Stabilization of Proteins: Towards Understanding the Significance of the Size of the Crowder
  119. Investigation of inhibitory potential of quercetin to the pyruvate dehydrogenase kinase 3: Towards implications in anticancer therapy
  120. Investigating architecture and structure-function relationships in cold shock DNA-binding domain family using structural genomics-based approach
  121. Unfoldness of the denatured state of proteins determines urea: Methylamine counteraction in terms of Gibbs free energy of stabilization
  122. Structural Analysis and Conformational Dynamics of STN1 Gene Mutations Involved in Coat Plus Syndrome
  123. Impact of Gln94Glu mutation on the structure and function of protection of telomere 1, a cause of cutaneous familial melanoma
  124. First evidence of formation of pre-molten globule state in myoglobin: A macromolecular crowding approach towards protein folding in vivo
  125. Protein stability: Determination of structure and stability of the transmembrane protein Mce4A from M. tuberculosis in membrane-like environment
  126. Spectroscopic, calorimetric and molecular docking insight into the interaction of Alzheimer’s drug donepezil with human transferrin: implications of Alzheimer’s drug
  127. Mixture of Macromolecular Crowding Agents Has a Non-additive Effect on the Stability of Proteins
  128. 2/3D-QSAR, molecular docking and MD simulation studies of FtsZ protein targeting benzimidazoles derivatives
  129. Protein folding: Molecular dynamics simulations and in vitro studies for probing mechanism of urea- and guanidinium chloride-induced unfolding of horse cytochrome-c
  130. Purification, modeling and structural insights of calmodulin-binding receptor like cytoplasmic kinase 2 from Oroxylum Indicum
  131. Circulation of single serotype of Dengue Virus (DENV-3) in New Delhi, India during 2016: A change in the epidemiological trend
  132. Investigation of deleterious effects of nsSNPs in thePOT1gene: a structural genomics‐based approach to understand the mechanism of cancer development
  133. Identification of potential inhibitors of sortase A: Binding studies, in-silico docking and protein-protein interaction studies of sortase A from Enterococcus faecalis
  134. Sequence, structure and evolutionary analysis of cold shock domain proteins, a member of OB fold family
  135. Unravelling the unfolding mechanism of human integrin linked kinase by GdmCl-induced denaturation
  136. Sugar osmolytes-induced stabilization of RNase A in macromolecular crowded cellular environment
  137. High throughput screening, docking and molecular dynamics studies to identify potential inhibitors of human calcium/calmodulin-dependent protein kinase IV
  138. Comparison of the thermal stabilization of proteins by oligosaccharides and monosaccharide mixtures: Measurement and analysis in the context of excluded volume theory
  139. Identification and evaluation of bioactive natural products as potential inhibitors of human microtubule affinity-regulating kinase 4 (MARK4)
  140. Mechanistic insights into the urea-induced denaturation of kinase domain of human integrin linked kinase
  141. Exploring molecular insights into the interaction mechanism of cholesterol derivatives with the Mce4A: A combined spectroscopic and molecular dynamic simulation studies
  142. Investigation of molecular mechanism of recognition between citral and MARK4: A newer therapeutic approach to attenuate cancer cell progression
  143. Counteraction of the deleterious effects of urea on structure and stability of mammalian kidney proteins by osmolytes
  144. Macromolecular crowding induces molten globule state in the native myoglobin at physiological pH
  145. Estimation of pH effect on the structure and stability of kinase domain of human Integrin linked kinase
  146. Estimation of thermodynamic stability of human carbonic anhydrase IX from urea-induced denaturation and MD simulation studies
  147. Effect of conservative mutations (L94V and L94I) on the structure and stability of horse cytochrome c
  148. New insights into the antioxidant and apoptotic potential of Glycyrrhiza glabra L. during hydrogen peroxide mediated oxidative stress: An in vitro and in silico evaluation
  149. Fas-activated serine/threonine kinase: Structure and function
  150. Elucidation of Dietary Polyphenolics as Potential Inhibitor of Microtubule Affinity Regulating Kinase 4: In silico and In vitro Studies
  151. Evidence of vanillin binding to CAMKIV explains the anti-cancer mechanism in human hepatic carcinoma and neuroblastoma cells
  152. Computing disease-linked SOD1 mutations: deciphering protein stability and patient-phenotype relations
  153. Characterization of intermediate state of myoglobin in the presence of PEG 10 under physiological conditions
  154. Non-enzymatic glycation enhances human serum albumin binding capacity to sodium fluorescein at room temperature: A spectroscopic analysis
  155. Effect of mammalian kidney osmolytes on the folding pathway of sheep serum albumin
  156. Binding studies and biological evaluation of β-carotene as a potential inhibitor of human calcium/calmodulin-dependent protein kinase IV
  157. Protein aggregation, misfolding and consequential human neurodegenerative diseases
  158. Size-dependent studies of macromolecular crowding on the thermodynamic stability, structure and functional activity of proteins: in vitro and in silico approaches
  159. Characterization of folding intermediates during urea-induced denaturation of human carbonic anhydrase II
  160. Data on the role of accessible surface area on osmolytes-induced protein stabilization
  161. Purification, preliminary X-ray crystallography and biophysical studies of triose phosphate isomerase-β-globin subunit complex
  162. The pH Dependence of Saccharides' Influence on Thermal Denaturation of Two Model Proteins Supports an Excluded Volume Model for Stabilization Generalized to Allow for Intramolecular Electrostatic Interactions
  163. Design, synthesis, and biological evaluation of pyrimidine derivatives as potential inhibitors of human calcium/calmodulin-dependent protein kinase IV
  164. Purification and structural characterization of Mce4A from Mycobacterium tuberculosis
  165. Refolding of urea denatured cytochrome c : Role of hydrophobic tail of the cationic gemini surfactants
  166. Ubiquitin-associated domain of MARK4 provides stability at physiological pH
  167. Evaluation of human microtubule affinity-regulating kinase 4 inhibitors: fluorescence binding studies, enzyme, and cell assays
  168. Effect of 1,4-bis(3-dodecylimidazolium-1-yl) butane bromide on channel form of gramicidin vesicles
  169. Protein aggregation and neurodegenerative diseases: From theory to therapy
  170. Structural and thermodynamic characterisation of L94F mutant of horse cytochrome c
  171. Structural insight into C9orf72 hexanucleotide repeat expansions: Towards new therapeutic targets in FTD-ALS
  172. Therapeutic progress in amyotrophic lateral sclerosis-beginning to learning
  173. GdnHCl-induced unfolding intermediate in the mitochondrial carbonic anhydrase VA
  174. Structural basis of urea-induced unfolding: Unraveling the folding pathway of hemochromatosis factor E
  175. Delineating the relationship between amyotrophic lateral sclerosis and frontotemporal dementia: Sequence and structure-based predictions
  176. Exploring Missense Mutations in Tyrosine Kinases Implicated with Neurodegeneration
  177. Effect of pH on the stability of hemochromatosis factor E: a combined spectroscopic and molecular dynamics simulation-based study
  178. Characterisation of molten globule-like state of sheep serum albumin at physiological pH
  179. Denatured states of yeast cytochrome c induced by heat and guanidinium chloride are structurally and thermodynamically different
  180. Effect of pH on the structure, function, and stability of human calcium/calmodulin-dependent protein kinase IV: combined spectroscopic and MD simulation studies
  181. GdmCl-induced unfolding studies of human carbonic anhydrase IX: a combined spectroscopic and MD simulation approach
  182. Probing pH sensitivity of αC-phycoerythrin and its natural truncant: A comparative study
  183. Calcium/calmodulin-dependent protein kinase IV: A multifunctional enzyme and potential therapeutic target
  184. Human Disease Insight: An integrated knowledge-based platform for disease-gene-drug information
  185. Despite an Extensive Sequence Analysis Identification of Functional Candidates Amongst Hypothetical Proteins of Neisseria gonorrhoeae
  186. Effect of pH on structure, function, and stability of mitochondrial carbonic anhydrase VA
  187. Urea-induced denaturation of human calcium/calmodulin-dependent protein kinase IV: a combined spectroscopic and MD simulation studies
  188. Purification and characterization of RGA2, a Rho2 GTPase-activating protein from Tinospora cordifolia
  189. Structure guided design of potential inhibitors of human calcium–calmodulin dependent protein kinase IV containing pyrimidine scaffold
  190. Testing the dependence of stabilizing effect of osmolytes on the fractional increase in the accessible surface area on thermal and chemical denaturations of proteins
  191. Spectroscopic and MD simulation studies on unfolding processes of mitochondrial carbonic anhydrase VA induced by urea
  192. Cloning, expression, purification and characterization of human mitochondrial carbonic anhydrase VA
  193. Functional annotation of putative conserved proteins from Borrelia burgdorferi to find potential drug targets
  194. Purification and characterization of Ras related protein, Rab5a from Tinospora cordifolia
  195. Purification and characterization of oligonucleotide binding (OB)-fold protein from medicinal plant Tinospora cordifolia
  196. Molecular basis of the structural stability of hemochromatosis factor E: A combined molecular dynamic simulation and GdmCl-induced denaturation study
  197. Chikungunya virus: recent advances in epidemiology, host pathogen interaction and vaccine strategies
  198. Designing New Kinase Inhibitor Derivatives as Therapeutics Against Common Complex Diseases: Structural Basis of Microtubule Affinity-Regulating Kinase 4 (MARK4) Inhibition
  199. PKR-inhibitor binds efficiently with human microtubule affinity-regulating kinase 4
  200. Biophysical characterization of G protein ectodomain of group B human respiratory syncytial virus fromE. coli
  201. Relationship between protein stability and functional activity in the presence of macromolecular crowding agents alone and in mixture: An insight into stability-activity trade-off
  202. Atypical PKC phosphorylates microtubule affinity-regulating kinase 4 in vitro
  203. Effect of dextran on the thermodynamic stability and structure of ribonuclease A
  204. Human microtubule affinity-regulating kinase 4 is stable at extremes of pH
  205. Cooperative Unfolding of Residual Structure in Heat Denatured Proteins by Urea and Guanidinium Chloride
  206. Thermal Stabilization of Proteins by Mono- and Oligosaccharides: Measurement and Analysis in the Context of an Excluded Volume Model
  207. Heterogeneity of Equilibrium Molten Globule State of Cytochrome c Induced by Weak Salt Denaturants under Physiological Condition
  208. Structural characterization of MG and pre-MG states of proteins by MD simulations, NMR, and other techniques
  209. Characterization of pre-molten globule state of yeast iso-1-cytochrome c and its deletants at pH 6.0 and 25 °C
  210. Structure-based functional annotation of hypothetical proteins from Candida dubliniensis: a quest for potential drug targets
  211. Structural Characterization, Homology Modeling and Docking Studies of ARG674 Mutation in MyH8 Gene Associated with Trismus-Pseudocamptodactyly Syndrome
  212. In vitro and in silico studies of urea-induced denaturation of yeast iso-1-cytochromecand its deletants at pH 6.0 and 25 °C
  213. Purification and Characterization of Calreticulin: a Ca2+-Binding Chaperone from Sheep Kidney
  214. Functional annotation of putative hypothetical proteins from Candida dubliniensis
  215. A Review of Methods Available to Estimate Solvent-Accessible Surface Areas of Soluble Proteins in the Folded and Unfolded States
  216. Folding and stability studies on C-PE and its natural N-terminal truncant
  217. Cloning, Expression, Purification and Refolding of Microtubule Affinity-Regulating Kinase 4 Expressed in Escherichia coli
  218. Effect of sequential deletion of extra N-terminal residues on the structure and stability of yeast iso-1-cytochrome-c
  219. Humanβ-Glucuronidase: Structure, Function, and Application in Enzyme Replacement Therapy
  220. Testing the Ability of Non-Methylamine Osmolytes Present in Kidney Cells to Counteract the Deleterious Effects of Urea on Structure, Stability and Function of Proteins
  221. The role of key residues in structure, function, and stability of cytochrome-c
  222. Microtubule Affinity-Regulating Kinase 4: Structure, Function, and Regulation
  223. Evidence of non-coincidence of normalized sigmoidal curves of two different structural properties for two-state protein folding/unfolding
  224. Why is Glycine not a Part of the Osmoticum in the Urea-rich Cells?
  225. Characterization of a Neutral and Thermostable Glucoamylase from the Thermophilic Mold Thermomucor indicae-seudaticae: Activity, Stability, and Structural Correlation
  226. Biophysical Analyses of Human Resistin: Oligomer Formation Suggests Novel Biological Function
  227. Purification and characterization of a trypsin inhibitor from Putranjiva roxburghii seeds
  228. Structure–function studies of Murraya koenigii trypsin inhibitor revealed a stable core beta sheet structure surrounded by α-helices with a possible role for α-helix in inhibitory function
  229. Role of unique basic residues of human pancreatic ribonuclease in its catalysis and structural stability
  230. Guanidinium chloride and urea denaturations of β-Lactoglobulin A at pH 2.0 and 25 °C: The equilibrium intermediate contains non-native structures (helix, tryptophan and hydrophobic patches)
  231. A Unique Molten Globule State Occurs during Unfolding of Cytochrome c by LiClO4 Near Physiological pH and Temperature: Structural and Thermodynamic Characterization
  232. Stability of proteins in the presence of polyols estimated from their guanidinium chloride-induced transition curves at different pH values and 25 °C