All Stories

  1. L-Pipecolic Acid-catalyzed Highly Efficient Synthesis of 2,4,5-Trisubstituted Imidazoles and N-cycloalkyl-2,4,5-trisubstituted Imidazoles
  2. Cu(II) and Fe(III) Catalyzed Synthesis of Novel Thiophene Hybridized Thiadiazolyl Schiff Bases (TTS) as COX-2 Selective Inhibitor
  3. Mechanistic exploration of the activities of poly(lactic-co-glycolic acid)-loaded nanoparticles of betulinic acid against hepatocellular carcinoma at cellular and molecular levels
  4. Author Correction: Novel Indole-fused benzo-oxazepines (IFBOs) inhibit invasion of hepatocellular carcinoma by targeting IL-6 mediated JAK2/STAT3 oncogenic signals
  5. Antineoplastic properties of zafirlukast against hepatocellular carcinoma via activation of mitochondrial mediated apoptosis
  6. Zolmitriptan attenuates hepatocellular carcinoma via activation of caspase mediated apoptosis
  7. Novel 1,3,4-thiadiazoles inhibit colorectal cancer via blockade of IL-6/COX-2 mediated JAK2/STAT3 signals as evidenced through data-based mathematical modeling
  8. Bioactive and drug-delivery potentials of polysaccharides and their derivatives
  9. Anti-spasmolytic and Anti-diarrheal Activities of Newbouldia laevis, Cola nitida and Acanthus montanus Extracts on Gastrointestinal Muscles
  10. Chemistry, Therapeutic Attributes, and Biological Activities of Dillenia indica Linn
  11. Betulinic acid as apoptosis activator: Molecular mechanisms, mathematical modeling and chemical modifications
  12. Discovery of Novel 2-Amino-5-(Substituted)-1,3,4-Thiadiazole Derivatives: New Utilities for Colon Cancer Treatment
  13. Novel 1,4-benzothazines obliterate COX-2 mediated JAK-2/STAT-3 signals with potential regulation of oxidative and metabolic stress during colorectal cancer
  14. Novel fused oxazepino-indoles (FOIs) attenuate liver carcinogenesis via IL-6/JAK2/STAT3 signaling blockade as evidenced through data-based mathematical modeling
  15. Novel Indole-fused benzo-oxazepines (IFBOs) inhibit invasion of hepatocellular carcinoma by targeting IL-6 mediated JAK2/STAT3 oncogenic signals
  16. 6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid attenuates colon carcinogenesis via blockade of IL-6 mediated signals
  17. Poly(lactic-co-glycolic acid)-loaded nanoparticles of betulinic acid for improved treatment of hepatic cancer: characterization, in vitro and in vivo evaluations
  18. Isolated mangiferin and naringenin exert antidiabetic effect via PPAR γ /GLUT4 dual agonistic action with strong metabolic regulation
  19. Modern Extraction Techniques for Drugs and Medicinal Agents
  20. Pharmacophore, 3D-QSAR Models and Dynamic Simulation of 1,4-Benzothiazines for Colorectal Cancer Treatment
  21. ω-3 Fatty Acid Synergized Novel Nanoemulsifying System for Rosuvastatin Delivery: In Vitro and In Vivo Evaluation
  22. 1,4-Benzothiazines-A Biologically Attractive Scaffold
  23. DETERMINATION OF 5H-BENZO[2,3][1,4]OXAZEPINO[5,6-B]INDOLES IN RAT PLASMA BY REVERSED-PHASE HIGH-PERFORMANCE LIQUID CHROMATOGRAPHIC-ULTRAVIOLET METHOD: APPLICATION TO PHARMACOKINETIC STUDIES
  24. Indole-fused azepines and analogues as anticancer lead molecules: Privileged findings and future directions
  25. Pharmacokinetics studies of single orally administered 1,3,4-thiadiazoles: method development and validation
  26. 5H-benzo[h]thiazolo[2,3-b]quinazolines ameliorate NDEA-induced hepatocellular carcinogenesis in rats through IL-6 downregulation along with oxidative and metabolic stress reduction
  27. Bridgehead Nitrogen Thiazolo[3,2-a]pyrimidine: A Privileged Structural Framework in Drug Discovery
  28. 6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid attenuates heptatocellular carcinoma in rats with NMR-based metabolic perturbations
  29. p-TSA-promoted syntheses of 5H-benzo[h]thiazolo[2,3-b]quinazoline and indeno[1,2-d]thiazolo[3,2-a]pyrimidine analogs: molecular modeling and in vitro antitumor activity against hepatocellular carcinoma
  30. Metabolomics approach discriminates toxicity index of pyrazinamide and its metabolic products, pyrazinoic acid and 5-hydroxy pyrazinoic acid
  31. Ameliorative effects of pyrazinoic acid against oxidative and metabolic stress manifested in rats with dimethylhydrazine induced colonic carcinoma
  32. Design and microwave facilitated green synthesis of 2-[4-(3-carboxymethyl, methoxy carbonylmethyl-2,4-dioxo and 4-oxo-2-thioxo-thiazolidin-5-ylidenemethyl)-phenoxy]-2 and 3-methyl propionic acid ethyl ester derivatives: a novel structural class of anti...
  33. Design and synthesis of 1,4-benzothiazine derivatives with promising effects against colorectal cancer cells
  34. Indole-fused benzooxazepines: a new structural class of anticancer agents
  35. Protective Effect of Naringin against Pylorus Ligation-induced Esophagitis in Male Wistar Rats
  36. OXIDATIVE STRESS-BASED HEPATOTOXICITY OF DULOXETINE IN WISTAR RATS
  37. An updated review on the phytochemistry, pharmacology, and clinical trials of Salacia oblonga
  38. Human Metabolic Enzymes Deficiency: A Genetic Mutation Based Approach
  39. Visual & reversible sensing of cyanide in real samples by an effective ratiometric colorimetric probe & logic gate application
  40. Antiproliferative effect of isolated isoquinoline alkaloid fromMucuna pruriensseeds in hepatic carcinoma cells
  41. Antidiabetic effects of isolated sterols from Ficus racemosa leaves
  42. Validation of rapid DNA extraction protocol and their effectiveness in marker assisted selection in crop plants
  43. Solar activity during first six years of solar cycle 24 and 23: a comparative study
  44. Galactomannan-PEI based non-viral vectors for targeted delivery of plasmid to macrophages and hepatocytes