All Stories

  1. Increased Pilus Production Conferred by a Naturally Occurring Mutation Alters Host-Pathogen Interaction in Favor of Carriage in Streptococcus pyogenes

    Article • Infection and Immunity, March 2017, ASM Journals

    Dr Anthony R Flores

  2. A Single Amino Acid Replacement in the Sensor Kinase LiaS Contributes to a Carrier Phenotype in Group A Streptococcus

    Article • Infection and Immunity, August 2015, ASM Journals

    Dr Anthony R Flores

  3. Sequence type 1 group B Streptococcus , an emerging cause of invasive disease in adults, evolves by small genetic changes

    Article • Proceedings of the National Academy of Sciences, May 2015, Proceedings of the National Academy of Sciences

    Dr Anthony R Flores, Dr Allison McGeer

  4. Natural Variant of Collagen-Like Protein A in Serotype M3 Group A Streptococcus Increases Adherence and Decreases Invasive Potential

    Article • Infection and Immunity, January 2015, ASM Journals

    Dr Anthony R Flores

  5. Asymptomatic Carriage of Group A Streptococcus Is Associated with Elimination of Capsule Production

    Article • Infection and Immunity, July 2014, ASM Journals

    Dr Anthony R Flores

  6. Streptococcus mitis Strains Causing Severe Clinical Disease in Cancer Patients

    Article • Emerging Infectious Diseases, May 2014, Centers for Disease Control and Prevention (CDC)

    Dr Anthony R Flores

  7. Molecular Characterization of an Invasive Phenotype of Group A Streptococcus Arising During Human Infection Using Whole Genome Sequencing of Multiple Isolates From the Same Patient

    Article • The Journal of Infectious Diseases, December 2013, Oxford University Press (OUP)

    Dr Anthony R Flores

  8. Natural Variation in the Promoter of the Gene Encoding the Mga Regulator Alters Host-Pathogen Interactions in Group A Streptococcus Carrier Strains

    Article • Infection and Immunity, August 2013, ASM Journals

    Dr Anthony R Flores, James Musser

  9. Differential Virulence Gene Expression of Group A Streptococcus Serotype M3 in Response to Co-Culture with Moraxella catarrhalis

    Article • PLoS ONE, April 2013, PLOS

    Dr Anthony R Flores, J HAYS

  10. Human Disease Isolates of Serotype M4 and M22 Group A Streptococcus Lack Genes Required for Hyaluronic Acid Capsule Biosynthesis

    Article • mBio, November 2012, ASM Journals

    Dr Anthony R Flores

  11. Full-Genome Dissection of an Epidemic of Severe Invasive Disease Caused by a Hypervirulent, Recently Emerged Clone of Group A Streptococcus

    Article • American Journal Of Pathology, April 2012, Elsevier

    Dr Anthony R Flores

  12. Polymorphisms in Regulator of Protease B (RopB) Alter Disease Phenotype and Strain Virulence of Serotype M3 Group A Streptococcus

    Article • The Journal of Infectious Diseases, January 2012, Oxford University Press (OUP)

    Dr Anthony R Flores, Professor ANDROULLA EFSTRATIOU

  13. Group A Streptococcus emm Gene Types in Pharyngeal Isolates, Ontario, Canada, 2002–2010

    Article • November 2011, Centers for Disease Control and Prevention (CDC)

    Dr Anthony R Flores

  14. Rapidly Progressive, Fatal, Inhalation Anthrax-like Infection in a Human: Case Report, Pathogen Genome Sequencing, Pathology, and Coordinated Response

    Article • Archives of Pathology & Laboratory Medicine, November 2011, Archives of Pathology and Laboratory Medicine

    Dr Anthony R Flores, Dr Scott W Long

  15. Distinct Single Amino Acid Replacements in the Control of Virulence Regulator Protein Differentially Impact Streptococcal Pathogenesis

    Article • PLoS Pathogens, October 2011, PLOS

    Dr Anthony R Flores

  16. Evolution of diversity in epidemics revealed by analysis of the human bacterial pathogen group A Streptococcus

    Article • Epidemics, September 2011, Elsevier

    Dr Anthony R Flores, Izabela Sitkiewicz

  17. Naturally occurring single amino acid replacements in a regulatory protein alter streptococcal gene expression and virulence in mice

    Article • Journal of Clinical Investigation, May 2011, American Society for Clinical Investigation

    Dr Anthony R Flores

  18. Distinct signatures of diversifying selection revealed by genome analysis of respiratory tract and invasive bacterial populations

    Article • Proceedings of the National Academy of Sciences, March 2011, Proceedings of the National Academy of Sciences

    Dr Anthony R Flores

  19. Pharyngitis

    Article • January 2010, Elsevier

    Dr Anthony R Flores

  20. The Twin-Arginine Translocation Pathway of Mycobacterium smegmatis Is Functional and Required for the Export of Mycobacterial β-Lactamases

    Article • Journal of Bacteriology, November 2005, ASM Journals

    Dr Anthony R Flores

  21. Characterization of Novel Mycobacterium tuberculosis and Mycobacterium smegmatis Mutants Hypersusceptible to β-Lactam Antibiotics

    Article • Journal of Bacteriology, March 2005, ASM Journals

    Dr Anthony R Flores