All Stories

  1. CETP Renaissance with Obicetrapib
  2. From child to family: rethinking cascade screening for elevated Lipoprotein(a)
  3. Upfront Combination or Stepwise Escalation: Personalising LDL-C Reduction in Clinical Practice
  4. Fibrates : Do They Still Have a Role in Therapy in 2025?
  5. Apolipoprotein B at the core: another step forward
  6. Lipoprotein (a): A new target for pharmacological research and an option for treatment
  7. PCSK9 reloaded: sirtuin-1 as a post-translational checkpoint for LDL-C control
  8. Beyond the mean: the prognostic value of lipid variability in atherosclerosis and mortality
  9. Oral PCSK9 Inhibitors: Will They Work?
  10. Apolipoprotein C3 and cardiovascular risk: new insights from the ODYSSEY outcomes trial
  11. LDL-cholesterol goal attainment with ezetimibe and bempedoic acid in patients at high and very-high cardiovascular risk: A simulation study in the Italian cohort of the SANTORINI study
  12. Can apoA-I infusion decrease cardiovascular events?
  13. Saturated vs. unsaturated fatty acids: should we reconsider their cardiovascular effects?
  14. In memoriam: Akira Endo
  15. Proprotein convertase subtilisisn/kexin type 9 inhibitors: the earlier the better?
  16. European Lipid Guidelines and Cardiovascular Risk Estimation: Current Status and Future Challenges
  17. Exploring apolipoprotein C-III: pathophysiological and pharmacological relevance
  18. How to Handle Elevated Triglycerides: Life after PROMINENT
  19. Disconnect between triglyceride reduction and cardiovascular outcomes: lessons from the PROMINENT and CLEAR Outcomes trials
  20. PCSK9 in extrahepatic tissues: What can we expect from its inhibition?
  21. Glycerol and β-hydroxybutyrate: friends or foes?
  22. Cardiovascular risk assessment: are we getting all the information we need?
  23. The burden of hypercholesterolemia and ischemic heart disease in an ageing world
  24. Lipid-lowering treatment and LDL-C goal attainment in high and very high cardiovascular risk patients: Evidence from the SANTORINI study-The Italian experience
  25. Remnant cholesterol: a reliable prognostic marker?
  26. Lp(a) as a Cardiovascular Risk Factor
  27. Inclisiran: How Widely and When Should We Use It?
  28. Evinacumab: a new option in the treatment of homozygous familial hypercholesterolemia
  29. Twelve Variants Polygenic Score for Low‐Density Lipoprotein Cholesterol Distribution in a Large Cohort of Patients With Clinically Diagnosed Familial Hypercholesterolemia With or Without Causative Mutations
  30. Understanding the efficacy and safety of lomitapide in homozygous familial hypercholesterolaemia
  31. New insights into the role of bempedoic acid and ezetimibe in the treatment of hypercholesterolemia
  32. Monoclonal Antibodies in the Management of Familial Hypercholesterolemia: Focus on PCSK9 and ANGPTL3 Inhibitors
  33. Lipoprotein remnants: to be or not to be
  34. Omega-3 for Cardiovascular Diseases: Where Do We Stand After REDUCE-IT and STRENGTH?
  35. HDL in Immune-Inflammatory Responses: Implications beyond Cardiovascular Diseases
  36. Global epidemiology of dyslipidaemias
  37. Recent insights into low-density lipoprotein metabolism and therapy
  38. Hypercholesterolemia and cardiovascular disease: Focus on high cardiovascular risk patients
  39. Hypercholesterolemia and cardiovascular disease: What to do before initiating pharmacological therapy
  40. Implementation of clinical practices and pathways optimizing ACS patients lipid management: Focus on eight European initiatives
  41. Improving lipid management in patients with acute coronary syndrome: The ACS Lipid EuroPath tool
  42. Lipid-lowering therapy and low-density lipoprotein cholesterol goal achievement in patients with acute coronary syndromes: The ACS patient pathway project
  43. Similarities and differences between European and American guidelines on the management of blood lipids to reduce cardiovascular risk
  44. Worldwide Changes in Total Cholesterol and Non-HDL-Cholesterol Trends Indicate Where the Challenges Are for the Coming Years
  45. Genetically determined hypercholesterolaemia results into premature leucocyte telomere length shortening and reduced haematopoietic precursors
  46. The cardiovascular benefit of Lp(a) reduction: not there yet
  47. Omega n-3 Supplementation: Exploring the Cardiovascular Benefits Beyond Lipoprotein Reduction
  48. Impact of protein glycosylation on lipoprotein metabolism and atherosclerosis
  49. New Pharmacological Approaches to Target PCSK9
  50. Insights from ORION studies: focus on inclisiran safety
  51. Beyond LDL-C levels, does remnant cholesterol estimation matter?
  52. LDL-Cholesterol-Lowering Therapy
  53. Dietary linoleic acid and human health: Focus on cardiovascular and cardiometabolic effects
  54. Cholesterol membrane content has a ubiquitous evolutionary function in immune cell activation
  55. Cholesterol metabolism, pancreatic β-cell function and diabetes
  56. The role of red yeast rice (RYR) supplementation in plasma cholesterol control: A review and expert opinion
  57. Statins increase Lp(a) plasma level: is this clinically relevant?
  58. Multilevel Models to Estimate Carotid Intima-Media Thickness Curves for Individual Cardiovascular Risk Evaluation
  59. Biological Consequences of Dysfunctional HDL
  60. Cardiovascular events with PCSK9 inhibitors: an updated meta-analysis of randomised controlled trials
  61. Novel strategies to target PCSK9: beyond monoclonal antibodies
  62. Increasing high-density lipoprotein cholesterol levels for cardiovascular benefit: The end of a dream?
  63. Lipid Lowering and Incidence of Cataract, a Role for Fibrates
  64. High-density lipoprotein cholesterol levels, cardiovascular disease risk, and cancer: a relation which does not apply to all?
  65. Evaluation of the performance of Dutch Lipid Clinic Network score in an Italian FH population: The LIPIGEN study
  66. PCSK9 inhibition and Lp(a) reduction: another piece of the puzzle?
  67. Proprotein Convertase Subtilisin Kexin 9 Inhibitors
  68. The Interplay of Lipids, Lipoproteins, and Immunity in Atherosclerosis
  69. Prevalence and management of familial hypercholesterolemia in patients with coronary artery disease: The heredity survey
  70. Familial Hypercholesterolemia
  71. Targeting Cholesterol in Non-ischemic Heart Failure: A Role for LDLR Gene Therapy?
  72. Spectrum of mutations in Italian patients with familial hypercholesterolemia: New results from the LIPIGEN study
  73. Anti-PCSK9 antibodies for the treatment of heterozygous familial hypercholesterolemia: patient selection and perspectives
  74. Strategies for the use of nonstatin therapies
  75. Statin use and risk of new-onset diabetes: a meta-analysis of observational studies
  76. Effect of PSCK9 loss-of-function mutation R46l on plasma lipids, endothelial function and vascular inflammation in the post-prandial state
  77. PCSK9 inhibition in statin-intolerant HeFH patients: What’s new?
  78. Pitavastatin and HDL: Effects on plasma levels and function(s)
  79. Vascular inflammation and low‐density lipoproteins: is cholesterol the link? A lesson from the clinical trials
  80. Statin use and risk of new-onset diabetes: A meta-analysis of observational studies
  81. Familial Hypercholesterolemia
  82. Advances in Hypercholesterolemia
  83. Biology of proprotein convertase subtilisin kexin 9: beyond low-density lipoprotein cholesterol lowering
  84. Niemann-Pick C1-Like 1 (NPC1L1) Inhibition and Cardiovascular Diseases
  85. Berberine, a plant alkaloid with lipid- and glucose-lowering properties: From in vitro evidence to clinical studies
  86. Apolipoprotein C-III: From Pathophysiology to Pharmacology
  87. Mutazioni del gene APOC3, metabolismo dei trigliceridi e riduzione di eventi ischemici cardiovascolari
  88. Statin Intolerance: Diagnosis and Remedies
  89. Update on the management of severe hypertriglyceridemia – focus on free fatty acid forms of omega-3
  90. Statins and Lomitapide: A Suitable Response for Homozygous Familial Hypercholesterolemia?
  91. HDL in Infectious Diseases and Sepsis
  92. Cardiometabolic and immune factors associated with increased common carotid artery intima-media thickness and cardiovascular disease in patients with systemic lupus erythematosus
  93. HDL in innate and adaptive immunity
  94. HDL: To Treat or Not To Treat?
  95. Postprandial lipemia as a cardiometabolic risk factor
  96. 15-Lipoxygenase-Mediated Modification of HDL3 Impairs eNOS Activation in Human Endothelial Cells
  97. Omega-3 polyunsaturated fatty acids in the treatment of hypertriglyceridaemia
  98. Prevalence of classical CD14++/CD16− but not of intermediate CD14++/CD16+ monocytes in hypoalphalipoproteinemia
  99. Omega-3 polyunsaturated fatty acids in the treatment of atherogenic dyslipidemia
  100. Production and Metabolism of Triglyceride-Rich Lipoproteins in Both the Normal and Diabetic States
  101. Treating High Density Lipoprotein Cholesterol (HDL-C): Quantity Versus Quality
  102. LOX-1, OxLDL, and Atherosclerosis
  103. High-Density Lipoprotein Subfractions - What the Clinicians Need to Know
  104. Soluble Lectin-Like Oxidized Low Density Lipoprotein Receptor-1 as a Biochemical Marker for Atherosclerosis-Related Diseases
  105. Upregulation of lectin-like oxidized low density lipoprotein receptor 1 (LOX-1) expression in human endothelial cells by modified high density lipoproteins
  106. Effect of treatment with pravastatin or ezetimibe on endothelial function in patients with moderate hypercholesterolemia
  107. Effector Memory T cells Are Associated With Atherosclerosis in Humans and Animal Models
  108. Effector Memory T cells Are Associated With Atherosclerosis in Humans and Animal Models
  109. Association between OLR1 K167N SNP and Intima Media Thickness of the Common Carotid Artery in the General Population
  110. Proprotein convertase subtilisin kexin type 9 (PCSK9) secreted by cultured smooth muscle cells reduces macrophages LDLR levels
  111. Emerging role of high density lipoproteins as a player in the immune system
  112. HDLs, immunity, and atherosclerosis
  113. Therapy and clinical trials
  114. Statins prevent tissue factor induction by protease-activated receptors 1 and 2 in human umbilical vein endothelial cells in vitro
  115. Upregulation of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) by 15-lipoxygenase-modified LDL in endothelial cells
  116. Dual effect of hypochlorite in the modification of high density lipoproteins
  117. The Challenge of Lipid Management in Patients with Diabetes or Other Endocrine Disorders
  118. The 15-lipoxygenase-modified HDL3 fail to inhibit the TNF- -induced inflammatory response in human endothelial cells
  119. The 15-Lipoxygenase-Modified High Density Lipoproteins 3 Fail to Inhibit the TNF- -Induced Inflammatory Response in Human Endothelial Cells
  120. EFFECTS OF NATIVE AND MODIFIED HDL ON HUMAN IMMUNE FUNCTIONS
  121. Long Pentraxin 3, a Key Component of Innate Immunity, Is Modulated by High-Density Lipoproteins in Endothelial Cells
  122. Modification of HDL3 by mild oxidative stress increases ATP-binding cassette transporter 1-mediated cholesterol efflux
  123. Anti-inflammatory and anti-atherogenic effects of cathechin, caffeic acid and trans-resveratrol in apolipoprotein E deficient mice
  124. Modified HDL: Biological and physiopathological consequences
  125. 15-Lipoxygenase-mediated modification of high-density lipoproteins impairs SR-BI- and ABCA1-dependent cholesterol efflux from macrophages
  126. In vitro isolation of circulating endothelial progenitor cells is related to the high density lipoprotein plasma levels
  127. Th-P15:162 15-Lipoxygenase-mediated modification of high density lipoproteins impairs SR-BI- and ABCA1-dependent cholesterol efflux from macrophages
  128. Proteome of endothelial cell-derived procoagulant microparticles
  129. Oxidised-HDL3 induces the expression of PAI-1 in human endothelial cells. Role of p38MAPK activation and mRNA stabilization
  130. Native LDL and Oxidized LDL modulate cyclooxygenase-2 expression in HUVECs through a p38-MAPK, NF-κB, CRE dependent pathway and affect PGE2 synthesis
  131. Gene expression and intracellular pathways involved in endothelial dysfunction induced by VLDL and oxidised VLDL
  132. Statins and Oxidative Stress During Atherogenesis
  133. Macrophage metalloproteinases degrade high-density-lipoprotein-associated apolipoprotein A-I at both the N- and C-termini
  134. Macrophage metalloproteinases degrade high-density-lipoprotein-associated apolipoprotein A-I at both the N- and C-termini
  135. Overexpression of Inducible Heat Shock Protein 70 in COS-1 Cells Fails to Protect From Cytotoxicity of Oxidized LDLs
  136. Modification of high density lipoproteins: Effects on OxLDL cytotoxicity and on cholesterol efflux
  137. Enhanced Macrophage Uptake of Elastase-Modified High-Density Lipoproteins
  138. Oxidized Lipoproteins and Endothelium
  139. Oxysterols from oxidized LDL are cytotoxic but fail to induce hsp70 expression in endothelial cells
  140. Procyanidines from vitis vinifera seeds protect low density lipoproteins from oxidation
  141. Endothelium and oxidised lipoproteins
  142. Chronic stimulation by insulin induces HSP60 expression in cultured eahy cells
  143. Overexpression of HSP72 in COS-1 cells does not protect from apoptosis induced by oxidized LDL
  144. 3.P.87 Two distinct components of oxidized LDL mediate the heat shock response and cytotoxicity triggered by OxLDL
  145. 3.P.255 Cholesterol biosynthesis pathway is involved in the heat shock protein and cytotoxic indicated by oxidized LDL in cultured human endothelial cells and smooth muscle cells
  146. Simvastatin Modulates the Heat Shock Response and Cytotoxicity Mediated by Oxidized LDL in Cultured Human Endothelial Smooth Muscle Cells
  147. Human Endothelial Cells Exposed to Oxidized LDL Express hsp70 Only When Proliferating
  148. Oxidized Ldl Trigger the Expression of Hsp70 in Cultured Endothelial Cells
  149. Oxidized LDL induce hsp70 expression in human smooth muscle cells
  150. Oxidized lipoproteins induce long-lasting inhibition of nitric oxide synthase from a murine endothelioma cell line (bEnd.4)
  151. Oxidized Lipoproteins Induce Long-Lasting Inhibition of Nitric Oxide Synthase from a Murine Endothelioma Cell Line (bEnd.4)
  152. Constituents of Nothapodytes foetida