All Stories

  1. From child to family: rethinking cascade screening for elevated Lipoprotein(a)
  2. Upfront Combination or Stepwise Escalation: Personalising LDL-C Reduction in Clinical Practice
  3. Fibrates : Do They Still Have a Role in Therapy in 2025?
  4. Apolipoprotein B at the core: another step forward
  5. Lipoprotein (a): A new target for pharmacological research and an option for treatment
  6. PCSK9 reloaded: sirtuin-1 as a post-translational checkpoint for LDL-C control
  7. Beyond the mean: the prognostic value of lipid variability in atherosclerosis and mortality
  8. Oral PCSK9 Inhibitors: Will They Work?
  9. Apolipoprotein C3 and cardiovascular risk: new insights from the ODYSSEY outcomes trial
  10. LDL-cholesterol goal attainment with ezetimibe and bempedoic acid in patients at high and very-high cardiovascular risk: A simulation study in the Italian cohort of the SANTORINI study
  11. Can apoA-I infusion decrease cardiovascular events?
  12. Saturated vs. unsaturated fatty acids: should we reconsider their cardiovascular effects?
  13. In memoriam: Akira Endo
  14. Proprotein convertase subtilisisn/kexin type 9 inhibitors: the earlier the better?
  15. European Lipid Guidelines and Cardiovascular Risk Estimation: Current Status and Future Challenges
  16. Exploring apolipoprotein C-III: pathophysiological and pharmacological relevance
  17. How to Handle Elevated Triglycerides: Life after PROMINENT
  18. Disconnect between triglyceride reduction and cardiovascular outcomes: lessons from the PROMINENT and CLEAR Outcomes trials
  19. PCSK9 in extrahepatic tissues: What can we expect from its inhibition?
  20. Glycerol and β-hydroxybutyrate: friends or foes?
  21. Cardiovascular risk assessment: are we getting all the information we need?
  22. The burden of hypercholesterolemia and ischemic heart disease in an ageing world
  23. Lipid-lowering treatment and LDL-C goal attainment in high and very high cardiovascular risk patients: Evidence from the SANTORINI study-The Italian experience
  24. Remnant cholesterol: a reliable prognostic marker?
  25. Lp(a) as a Cardiovascular Risk Factor
  26. Inclisiran: How Widely and When Should We Use It?
  27. Evinacumab: a new option in the treatment of homozygous familial hypercholesterolemia
  28. Twelve Variants Polygenic Score for Low‐Density Lipoprotein Cholesterol Distribution in a Large Cohort of Patients With Clinically Diagnosed Familial Hypercholesterolemia With or Without Causative Mutations
  29. Understanding the efficacy and safety of lomitapide in homozygous familial hypercholesterolaemia
  30. New insights into the role of bempedoic acid and ezetimibe in the treatment of hypercholesterolemia
  31. Monoclonal Antibodies in the Management of Familial Hypercholesterolemia: Focus on PCSK9 and ANGPTL3 Inhibitors
  32. Lipoprotein remnants: to be or not to be
  33. Omega-3 for Cardiovascular Diseases: Where Do We Stand After REDUCE-IT and STRENGTH?
  34. HDL in Immune-Inflammatory Responses: Implications beyond Cardiovascular Diseases
  35. Global epidemiology of dyslipidaemias
  36. Recent insights into low-density lipoprotein metabolism and therapy
  37. Hypercholesterolemia and cardiovascular disease: Focus on high cardiovascular risk patients
  38. Hypercholesterolemia and cardiovascular disease: What to do before initiating pharmacological therapy
  39. Implementation of clinical practices and pathways optimizing ACS patients lipid management: Focus on eight European initiatives
  40. Improving lipid management in patients with acute coronary syndrome: The ACS Lipid EuroPath tool
  41. Lipid-lowering therapy and low-density lipoprotein cholesterol goal achievement in patients with acute coronary syndromes: The ACS patient pathway project
  42. Similarities and differences between European and American guidelines on the management of blood lipids to reduce cardiovascular risk
  43. Worldwide Changes in Total Cholesterol and Non-HDL-Cholesterol Trends Indicate Where the Challenges Are for the Coming Years
  44. Genetically determined hypercholesterolaemia results into premature leucocyte telomere length shortening and reduced haematopoietic precursors
  45. The cardiovascular benefit of Lp(a) reduction: not there yet
  46. Omega n-3 Supplementation: Exploring the Cardiovascular Benefits Beyond Lipoprotein Reduction
  47. Impact of protein glycosylation on lipoprotein metabolism and atherosclerosis
  48. New Pharmacological Approaches to Target PCSK9
  49. Insights from ORION studies: focus on inclisiran safety
  50. Beyond LDL-C levels, does remnant cholesterol estimation matter?
  51. LDL-Cholesterol-Lowering Therapy
  52. Dietary linoleic acid and human health: Focus on cardiovascular and cardiometabolic effects
  53. Cholesterol membrane content has a ubiquitous evolutionary function in immune cell activation
  54. Cholesterol metabolism, pancreatic β-cell function and diabetes
  55. The role of red yeast rice (RYR) supplementation in plasma cholesterol control: A review and expert opinion
  56. Statins increase Lp(a) plasma level: is this clinically relevant?
  57. Multilevel Models to Estimate Carotid Intima-Media Thickness Curves for Individual Cardiovascular Risk Evaluation
  58. Biological Consequences of Dysfunctional HDL
  59. Cardiovascular events with PCSK9 inhibitors: an updated meta-analysis of randomised controlled trials
  60. Novel strategies to target PCSK9: beyond monoclonal antibodies
  61. Increasing high-density lipoprotein cholesterol levels for cardiovascular benefit: The end of a dream?
  62. Lipid Lowering and Incidence of Cataract, a Role for Fibrates
  63. High-density lipoprotein cholesterol levels, cardiovascular disease risk, and cancer: a relation which does not apply to all?
  64. Evaluation of the performance of Dutch Lipid Clinic Network score in an Italian FH population: The LIPIGEN study
  65. PCSK9 inhibition and Lp(a) reduction: another piece of the puzzle?
  66. Proprotein Convertase Subtilisin Kexin 9 Inhibitors
  67. The Interplay of Lipids, Lipoproteins, and Immunity in Atherosclerosis
  68. Prevalence and management of familial hypercholesterolemia in patients with coronary artery disease: The heredity survey
  69. Familial Hypercholesterolemia
  70. Targeting Cholesterol in Non-ischemic Heart Failure: A Role for LDLR Gene Therapy?
  71. Spectrum of mutations in Italian patients with familial hypercholesterolemia: New results from the LIPIGEN study
  72. Anti-PCSK9 antibodies for the treatment of heterozygous familial hypercholesterolemia: patient selection and perspectives
  73. Strategies for the use of nonstatin therapies
  74. Statin use and risk of new-onset diabetes: a meta-analysis of observational studies
  75. Effect of PSCK9 loss-of-function mutation R46l on plasma lipids, endothelial function and vascular inflammation in the post-prandial state
  76. PCSK9 inhibition in statin-intolerant HeFH patients: What’s new?
  77. Pitavastatin and HDL: Effects on plasma levels and function(s)
  78. Vascular inflammation and low‐density lipoproteins: is cholesterol the link? A lesson from the clinical trials
  79. Statin use and risk of new-onset diabetes: A meta-analysis of observational studies
  80. Familial Hypercholesterolemia
  81. Advances in Hypercholesterolemia
  82. Biology of proprotein convertase subtilisin kexin 9: beyond low-density lipoprotein cholesterol lowering
  83. Niemann-Pick C1-Like 1 (NPC1L1) Inhibition and Cardiovascular Diseases
  84. Berberine, a plant alkaloid with lipid- and glucose-lowering properties: From in vitro evidence to clinical studies
  85. Apolipoprotein C-III: From Pathophysiology to Pharmacology
  86. Mutazioni del gene APOC3, metabolismo dei trigliceridi e riduzione di eventi ischemici cardiovascolari
  87. Statin Intolerance: Diagnosis and Remedies
  88. Update on the management of severe hypertriglyceridemia – focus on free fatty acid forms of omega-3
  89. Statins and Lomitapide: A Suitable Response for Homozygous Familial Hypercholesterolemia?
  90. HDL in Infectious Diseases and Sepsis
  91. Cardiometabolic and immune factors associated with increased common carotid artery intima-media thickness and cardiovascular disease in patients with systemic lupus erythematosus
  92. HDL in innate and adaptive immunity
  93. HDL: To Treat or Not To Treat?
  94. Postprandial lipemia as a cardiometabolic risk factor
  95. 15-Lipoxygenase-Mediated Modification of HDL3 Impairs eNOS Activation in Human Endothelial Cells
  96. Omega-3 polyunsaturated fatty acids in the treatment of hypertriglyceridaemia
  97. Prevalence of classical CD14++/CD16− but not of intermediate CD14++/CD16+ monocytes in hypoalphalipoproteinemia
  98. Omega-3 polyunsaturated fatty acids in the treatment of atherogenic dyslipidemia
  99. Production and Metabolism of Triglyceride-Rich Lipoproteins in Both the Normal and Diabetic States
  100. Treating High Density Lipoprotein Cholesterol (HDL-C): Quantity Versus Quality
  101. LOX-1, OxLDL, and Atherosclerosis
  102. High-Density Lipoprotein Subfractions - What the Clinicians Need to Know
  103. Soluble Lectin-Like Oxidized Low Density Lipoprotein Receptor-1 as a Biochemical Marker for Atherosclerosis-Related Diseases
  104. Upregulation of lectin-like oxidized low density lipoprotein receptor 1 (LOX-1) expression in human endothelial cells by modified high density lipoproteins
  105. Effect of treatment with pravastatin or ezetimibe on endothelial function in patients with moderate hypercholesterolemia
  106. Effector Memory T cells Are Associated With Atherosclerosis in Humans and Animal Models
  107. Effector Memory T cells Are Associated With Atherosclerosis in Humans and Animal Models
  108. Association between OLR1 K167N SNP and Intima Media Thickness of the Common Carotid Artery in the General Population
  109. Proprotein convertase subtilisin kexin type 9 (PCSK9) secreted by cultured smooth muscle cells reduces macrophages LDLR levels
  110. Emerging role of high density lipoproteins as a player in the immune system
  111. HDLs, immunity, and atherosclerosis
  112. Therapy and clinical trials
  113. Statins prevent tissue factor induction by protease-activated receptors 1 and 2 in human umbilical vein endothelial cells in vitro
  114. Upregulation of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) by 15-lipoxygenase-modified LDL in endothelial cells
  115. Dual effect of hypochlorite in the modification of high density lipoproteins
  116. The Challenge of Lipid Management in Patients with Diabetes or Other Endocrine Disorders
  117. The 15-lipoxygenase-modified HDL3 fail to inhibit the TNF- -induced inflammatory response in human endothelial cells
  118. The 15-Lipoxygenase-Modified High Density Lipoproteins 3 Fail to Inhibit the TNF- -Induced Inflammatory Response in Human Endothelial Cells
  119. EFFECTS OF NATIVE AND MODIFIED HDL ON HUMAN IMMUNE FUNCTIONS
  120. Long Pentraxin 3, a Key Component of Innate Immunity, Is Modulated by High-Density Lipoproteins in Endothelial Cells
  121. Modification of HDL3 by mild oxidative stress increases ATP-binding cassette transporter 1-mediated cholesterol efflux
  122. Anti-inflammatory and anti-atherogenic effects of cathechin, caffeic acid and trans-resveratrol in apolipoprotein E deficient mice
  123. Modified HDL: Biological and physiopathological consequences
  124. 15-Lipoxygenase-mediated modification of high-density lipoproteins impairs SR-BI- and ABCA1-dependent cholesterol efflux from macrophages
  125. In vitro isolation of circulating endothelial progenitor cells is related to the high density lipoprotein plasma levels
  126. Th-P15:162 15-Lipoxygenase-mediated modification of high density lipoproteins impairs SR-BI- and ABCA1-dependent cholesterol efflux from macrophages
  127. Proteome of endothelial cell-derived procoagulant microparticles
  128. Oxidised-HDL3 induces the expression of PAI-1 in human endothelial cells. Role of p38MAPK activation and mRNA stabilization
  129. Native LDL and Oxidized LDL modulate cyclooxygenase-2 expression in HUVECs through a p38-MAPK, NF-κB, CRE dependent pathway and affect PGE2 synthesis
  130. Gene expression and intracellular pathways involved in endothelial dysfunction induced by VLDL and oxidised VLDL
  131. Statins and Oxidative Stress During Atherogenesis
  132. Macrophage metalloproteinases degrade high-density-lipoprotein-associated apolipoprotein A-I at both the N- and C-termini
  133. Macrophage metalloproteinases degrade high-density-lipoprotein-associated apolipoprotein A-I at both the N- and C-termini
  134. Overexpression of Inducible Heat Shock Protein 70 in COS-1 Cells Fails to Protect From Cytotoxicity of Oxidized LDLs
  135. Modification of high density lipoproteins: Effects on OxLDL cytotoxicity and on cholesterol efflux
  136. Enhanced Macrophage Uptake of Elastase-Modified High-Density Lipoproteins
  137. Oxidized Lipoproteins and Endothelium
  138. Oxysterols from oxidized LDL are cytotoxic but fail to induce hsp70 expression in endothelial cells
  139. Procyanidines from vitis vinifera seeds protect low density lipoproteins from oxidation
  140. Endothelium and oxidised lipoproteins
  141. Chronic stimulation by insulin induces HSP60 expression in cultured eahy cells
  142. Overexpression of HSP72 in COS-1 cells does not protect from apoptosis induced by oxidized LDL
  143. 3.P.87 Two distinct components of oxidized LDL mediate the heat shock response and cytotoxicity triggered by OxLDL
  144. 3.P.255 Cholesterol biosynthesis pathway is involved in the heat shock protein and cytotoxic indicated by oxidized LDL in cultured human endothelial cells and smooth muscle cells
  145. Simvastatin Modulates the Heat Shock Response and Cytotoxicity Mediated by Oxidized LDL in Cultured Human Endothelial Smooth Muscle Cells
  146. Human Endothelial Cells Exposed to Oxidized LDL Express hsp70 Only When Proliferating
  147. Oxidized Ldl Trigger the Expression of Hsp70 in Cultured Endothelial Cells
  148. Oxidized LDL induce hsp70 expression in human smooth muscle cells
  149. Oxidized lipoproteins induce long-lasting inhibition of nitric oxide synthase from a murine endothelioma cell line (bEnd.4)
  150. Oxidized Lipoproteins Induce Long-Lasting Inhibition of Nitric Oxide Synthase from a Murine Endothelioma Cell Line (bEnd.4)
  151. Constituents of Nothapodytes foetida