All Stories

  1. Corrigendum to “Distinct mutational features across preinvasive and invasive subtypes identified through comprehensive profiling of surgically resected lung adenocarcinoma” [Modern Pathology. 2022;35(9):1181-1192]
  2. Individualized dynamic methylation-based analysis of cell-free DNA in postoperative monitoring of lung cancer
  3. Blood-based DNA methylation profiling for the detection of ovarian cancer
  4. Distinct mutational features across preinvasive and invasive subtypes identified through comprehensive profiling of surgically resected lung adenocarcinoma
  5. The utility of sputum supernatant as an alternative liquid biopsy specimen for next-generation sequencing-based somatic variation profiling
  6. Disease progression patterns and molecular resistance mechanisms to crizotinib of lung adenocarcinoma harboring ROS1 rearrangements
  7. Effective response to crizotinib of concurrent KIF5B-MET and MET-CDR2-rearranged non-small cell lung cancer: A case report
  8. Molecular characterization and clinical outcomes in EGFR-mutant de novo MET-overexpressed advanced non-small-cell lung cancer
  9. Clinical and molecular feature-based nomogram model for predicting benefit from bevacizumab combined with first-generation EGFR-tyrosine kinase inhibitor (TKI) in EGFR-mutant advanced NSCLC
  10. Potential utility of longitudinal somatic mutation and methylation profiling for predicting molecular residual disease in postoperative non‐small cell lung cancer patients
  11. Clinical and molecular factors that impact the efficacy of first-line crizotinib in ROS1-rearranged non-small-cell lung cancer: a large multicenter retrospective study
  12. Lung Adenocarcinoma Harboring Concomitant EGFR Mutations and BRAF V600E Responds to a Combination of Osimertinib and Vemurafenib to Overcome Osimertinib Resistance
  13. Characterization of Frequently Mutated Cancer Genes and Tumor Mutation Burden in Chinese Breast Cancer
  14. Brigatinib After Progression From Alectinib or Crizotinib: Paving the Way for Treatment Sequencing of ALK Inhibitors in ALK-Positive NSCLC
  15. Differences in the clinicopathological characteristics of pure and mixed invasive micropapillary breast carcinomas from eastern China
  16. Anlotinib combined with PD-1 blockade for the treatment of lung cancer: a real-world retrospective study in China
  17. Heterogeneous constitutional mismatch repair deficiency with MSH6 missense mutation clinically benefits from pembrolizumab and regorafenib combination therapy: a case report and literature review
  18. Mutational Landscape of PI3K-AKT-mTOR Pathway in Breast Cancer: Implications for Targeted Therapeutics
  19. The emergence of various genetic alterations mediated the Osimertinib resistance of a patient harboring heterozygous germline EGFR T790M: a case report
  20. The prognostic value of longitudinal circulating tumor DNA profiling during osimertinib treatment
  21. The efficacy of lorlatinib in a lung adenocarcinoma patient with a novel ALK G1202L mutation: a case report
  22. Clinical impact of uncommon epidermal growth factor receptor exon 19 insertion-deletion variants on epidermal growth factor receptor-tyrosine kinase inhibitor efficacy in non-small-cell lung cancer
  23. A reply to “MET-mutant cancer and immune checkpoint inhibitors: A large database analysis”
  24. A reply to “ROS1-mutant cancer and immune checkpoint inhibitors: A large database analysis”
  25. Integrated histological and molecular analyses of rebiopsy samples at osimertinib progression improve post-progression survivals: A single-center retrospective study
  26. Investigation on the potential of circulating tumor DNA methylation patterns as prognostic biomarkers for lung squamous cell carcinoma
  27. Third left pulmonary lobe
  28. The utility of sputum supernatant as an alternative liquid biopsy specimen for next-generation sequencing-based genomic profiling
  29. Characterization of MET exon 14 alteration and association with clinical outcomes of crizotinib in Chinese lung cancers
  30. Effective Treatment of Lung Adenocarcinoma Harboring EGFR-Activating Mutation, T790M, and cis-C797S Triple Mutations by Brigatinib and Cetuximab Combination Therapy
  31. Investigation on the prognostic impact of concurrent genomic alterations in crizotinib-treated EML4-ALK-rearranged advanced non-small cell lung cancer patients
  32. The clinical efficacy of combinatorial therapy of EGFR-TKI and crizotinib in overcoming MET amplification-mediated resistance from prior EGFR-TKI therapy
  33. A Burning External Colon Cancer Patient With Diffuse Miliary Peritoneal Metastases
  34. <p>Comparison of Next-Generation Sequencing and Ventana Immunohistochemistry in Detecting ALK Rearrangements and Predicting the Efficacy of First-Line Crizotinib in Patients with Advanced Non-Small Cell Lung Cancer</p>
  35. Detection of Microsatellite Instability from Circulating Tumor DNA by Targeted Deep Sequencing
  36. Efficacy of Joungal in preventing febrile neutropenia induced by platinum-based doublet chemotherapy in lung cancer
  37. Characterizations of Cancer Gene Mutations in Chinese Metastatic Breast Cancer Patients
  38. A novel ROS1 G2032 K missense mutation mediates lorlatinib resistance in a patient with ROS1-rearranged lung adenocarcinoma but responds to nab-paclitaxel plus pembrolizumab
  39. Comparison of BRCA versus non-BRCA germline mutations and associated somatic mutation profiles in patients with unselected breast cancer
  40. Detection of Nonreciprocal/Reciprocal ALK Translocation as Poor Predictive Marker in Patients With First-Line Crizotinib-Treated ALK-Rearranged NSCLC
  41. Rechallenge with erlotinib in osimertinib-resistant lung adenocarcinoma mediated by driver gene loss: a case report
  42. Tumor mutation burden derived from small next generation sequencing targeted gene panel as an initial screening method
  43. Unique molecular features and clinical outcomes in young patients with non-small cell lung cancer harboring ALK fusion genes
  44. Erratum to Prevalence and clinical significance of pathogenic germline <i>BRCA1/2</i> mutations in Chinese non-small cell lung cancer patients
  45. Acquired multiple mutations ALK I1171N, L1196M and G1202R mediate lorlatinib resistance in EML4-ALK-rearranged malignant pleural mesothelioma: a case report
  46. Efficacy of erlotinib as neoadjuvant regimen in EGFR-mutant locally advanced non-small cell lung cancer patients
  47. Parallel serial assessment of somatic mutation and methylation profile from circulating tumor DNA predicts treatment response and impending disease progression in osimertinib-treated lung adenocarcinoma patients
  48. Sequential ALK inhibitor treatment benefits patient with leptomeningeal metastasis harboring non‐EML4‐ALK rearrangements detected from cerebrospinal fluid: A case report
  49. Comparative study on the mutational profile of adenocarcinoma and squamous cell carcinoma predominant histologic subtypes in Chinese non‐small cell lung cancer patients
  50. A multicenter analysis of genomic profiles and PD-L1 expression of primary lymphoepithelioma-like carcinoma of the lung
  51. Mutational profiling of poorly differentiated and anaplastic thyroid carcinoma by the use of targeted next‐generation sequencing
  52. Targeted sequencing identifies the mutational signature of double primary and metastatic malignancies: a case report
  53. The association between BRAF mutation class and clinical features in BRAF-mutant Chinese non-small cell lung cancer patients
  54. Prevalence and clinical significance of pathogenic germline BRCA1/2 mutations in Chinese non-small cell lung cancer patients
  55. Somatic mutations in KMT2D and TET2 associated with worse prognosis in Epstein-Barr virus-associated T or natural killer-cell lymphoproliferative disorders
  56. Efficacy of afatinib in a HER2 amplification-positive endometrioid adenocarcinoma patient– a case report
  57. Detecting Ultralow Frequency Mutation in Circulating Cell‐Free DNA of Early‐Stage Nonsmall Cell Lung Cancer Patients with Unique Molecular Identifiers
  58. The in cis compound EGFR mutations in Chinese advanced non-small cell lung cancer patients
  59. Malignant pleural effusion supernatant is an alternative liquid biopsy specimen for comprehensive mutational profiling
  60. SIM2 maintains innate host defense of the small intestine
  61. β-adrenergic receptor-stimulated lipolysis requires the RAB7-mediated autolysosomal lipid degradation