All Stories

  1. Proteome-wide analysis of chaperone-mediated autophagy targeting motifs

    Article • PLoS Biology, May 2019, PLOS

    Dr Ana Maria Cuervo

  2. The negative effect of lipid challenge on autophagy inhibits T cell responses

    Article • Autophagy, April 2019, Taylor & Francis

    Professor Laura santambrogio, Dr Ana Maria Cuervo

  3. Transcription factor NFE2L2/NRF2 modulates chaperone-mediated autophagy through the regulation of LAMP2A

    Article • Autophagy, July 2018, Taylor & Francis

    Dr Ana Maria Cuervo

  4. Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis

    Article • Nature Cell Biology, May 2015, Springer Science + Business Media

    Dr Ana Maria Cuervo

  5. HTT/Huntingtin in selective autophagy and Huntington disease: A foe or a friend within?

    Article • Autophagy, May 2015, Taylor & Francis

    Dr Ana Maria Cuervo

  6. Selective autophagy and Huntingtin: learning from disease

    Article • Cell Cycle, April 2015, Taylor & Francis

    Dr Ana Maria Cuervo

  7. Regulated degradation of Chk1 by chaperone-mediated autophagy in response to DNA damage

    Article • Nature Communications, April 2015, Springer Science + Business Media

    Dr Ana Maria Cuervo

  8. Methods to study chaperone-mediated autophagy

    Article • Methods, March 2015, Elsevier

    Dr Ana Maria Cuervo

  9. Huntingtin functions as a scaffold for selective macroautophagy

    Article • Nature Cell Biology, February 2015, Springer Science + Business Media

    Dr Ana Maria Cuervo

  10. Loss of hepatic chaperone‐mediated autophagy accelerates proteostasis failure in aging

    Article • Aging Cell, January 2015, Wiley

    Dr Ana Maria Cuervo

  11. Annexin A2 promotes phagophore assembly by enhancing Atg16L+ vesicle biogenesis and homotypic fusion

    Article • Nature Communications, January 2015, Springer Science + Business Media

    Dr Ana Maria Cuervo

  12. The Role of Autophagy in Liver Diseases: Mechanisms and Potential Therapeutic Targets

    Article • BioMed Research International, January 2015, Hindawi Publishing Corporation

    Dr Ana Maria Cuervo

  13. Hydrodynamic size-based separation and characterization of protein aggregates from total cell lysates

    Article • Nature Protocols, December 2014, Springer Science + Business Media

    Dr Ana Maria Cuervo

  14. Geroscience: Linking Aging to Chronic Disease

    Article • Cell, November 2014, Elsevier

    Dr Ana Maria Cuervo

  15. Chaperone-mediated autophagy regulates T cell responses through targeted degradation of negative regulators of T cell activation

    Article • Nature Immunology, September 2014, Springer Science + Business Media

    Dr Ana Maria Cuervo

  16. Deficient Chaperone-Mediated Autophagy in Liver Leads to Metabolic Dysregulation

    Article • Cell Metabolism, September 2014, Elsevier

    Dr Ana Maria Cuervo

  17. Autophagy and the immune function in aging

    Article • Current Opinion in Immunology, August 2014, Elsevier

    Dr Ana Maria Cuervo

  18. Connexins modulate autophagosome biogenesis

    Article • Nature Cell Biology, April 2014, Springer Science + Business Media

    Dr Ana Maria Cuervo

  19. Chaperone-mediated autophagy: roles in disease and aging

    Article • Cell Research, November 2013, Springer Science + Business Media

    Dr Ana Maria Cuervo

  20. Liver autophagy: much more than just taking out the trash

    Article • Nature Reviews Gastroenterology & Hepatology, November 2013, Springer Science + Business Media

    Dr Ana Maria Cuervo

  21. Erratum: Corrigendum: Chemical modulation of chaperone-mediated autophagy by retinoic acid derivatives

    Article • Nature Chemical Biology, October 2013, Springer Science + Business Media

    Dr Ana Maria Cuervo

  22. Functional interaction between autophagy and ciliogenesis

    Article • Nature, October 2013, Springer Science + Business Media

    Dr Ana Maria Cuervo

  23. Autophagy and neurodegeneration

    Article • Alzheimer s & Dementia, July 2013, Elsevier

    Dr Ana Maria Cuervo

  24. Preventing lysosomal fat indigestion

    Article • Nature Cell Biology, June 2013, Springer Science + Business Media

    Dr Ana Maria Cuervo

  25. Selective Autophagy: Talking with the UPS

    Article • Cell Biochemistry and Biophysics, May 2013, Springer Science + Business Media

    Dr Ana Maria Cuervo

  26. Chemical modulation of chaperone-mediated autophagy by retinoic acid derivatives

    Article • Nature Chemical Biology, April 2013, Springer Science + Business Media

    Dr Ana Maria Cuervo

  27. Interplay of LRRK2 with chaperone-mediated autophagy

    Article • Nature Neuroscience, March 2013, Springer Science + Business Media

    Dr Ana Maria Cuervo

  28. The lipid kinase PI4KIIIβ preserves lysosomal identity

    Article • The EMBO Journal, December 2012, Wiley

    Dr Ana Maria Cuervo

  29. Chaperones in autophagy

    Article • Pharmacological Research, December 2012, Elsevier

    Dr Ana Maria Cuervo

  30. Selective autophagy in cellular quality control

    Article • October 2012, Springer Science + Business Media

    Dr Ana Maria Cuervo

  31. Chaperone-mediated autophagy: a unique way to enter the lysosome world

    Article • Trends in Cell Biology, August 2012, Elsevier

    Dr Ana Maria Cuervo

  32. Dietary lipids and aging compromise chaperone-mediated autophagy by similar mechanisms

    Article • Autophagy, July 2012, Taylor & Francis

    Dr Ana Maria Cuervo

  33. Autophagy, nutrition and immunology

    Article • Molecular Aspects of Medicine, February 2012, Elsevier

    Dr Ana Maria Cuervo

  34. Molecular determinants of selective clearance of protein inclusions by autophagy

    Article • Nature Communications, January 2012, Springer Science + Business Media

    Dr Ana Maria Cuervo

  35. Lipophagy: Connecting Autophagy and Lipid Metabolism

    Article • International Journal of Cell Biology, January 2012, Hindawi Publishing Corporation

    Dr Ana Maria Cuervo

  36. Autophagy and disease: always two sides to a problem

    Article • The Journal of Pathology, November 2011, Wiley

    Dr Ana Maria Cuervo

  37. Chaperone-mediated autophagy: Dice's 'wild' idea about lysosomal selectivity

    Article • Nature Reviews Molecular Cell Biology, July 2011, Springer Science + Business Media

    Dr Ana Maria Cuervo

  38. A photoconvertible fluorescent reporter to track chaperone-mediated autophagy

    Article • Nature Communications, July 2011, Springer Science + Business Media

    Dr Ana Maria Cuervo

  39. Chaperone-mediated autophagy dysfunction in the pathogenesis of neurodegeneration

    Article • Neurobiology of Disease, July 2011, Elsevier

    Dr Ana Maria Cuervo

  40. Chasing the elusive mammalian microautophagy

    Article • Autophagy, June 2011, Taylor & Francis

    Dr Ana Maria Cuervo

  41. Autophagy in the Cellular Energetic Balance

    Article • Cell Metabolism, May 2011, Elsevier

    Dr Ana Maria Cuervo

  42. Protein homeostasis and aging: The importance of exquisite quality control

    Article • Ageing Research Reviews, April 2011, Elsevier

    Dr Ana Maria Cuervo

  43. Chaperone-mediated autophagy in protein quality control

    Article • Current Opinion in Cell Biology, April 2011, Elsevier

    Dr Ana Maria Cuervo

  44. Microautophagy of Cytosolic Proteins by Late Endosomes

    Article • Developmental Cell, March 2011, Elsevier

    Dr Ana Maria Cuervo

  45. Protein Homeostasis and Aging

    Article • January 2011, Elsevier

    Dr Ana Maria Cuervo

  46. Microautophagy of Cytosolic Proteins by Late Endosomes

    Article • Developmental Cell, January 2011, Elsevier

    Dr Ana Maria Cuervo

  47. Autophagy and lipids: tightening the knot

    Article • Seminars in Immunopathology, August 2010, Springer Science + Business Media

    Dr Ana Maria Cuervo

  48. Inhibitory effect of intracellular lipid load on macroautophagy

    Article • Autophagy, August 2010, Taylor & Francis

    Dr Ana Maria Cuervo

  49. Identification of Regulators of Chaperone-Mediated Autophagy

    Article • Molecular Cell, August 2010, Elsevier

    Dr Ana Maria Cuervo

  50. The plasma membrane brings autophagosomes to life

    Article • Nature Cell Biology, August 2010, Springer Science + Business Media

    Dr Ana Maria Cuervo

  51. Autophagy: An Alternative Degradation Mechanism for Misfolded Proteins

    Article • July 2010, Wiley

    Dr Ana Maria Cuervo

  52. Autophagy gone awry in neurodegenerative diseases

    Article • Nature Neuroscience, June 2010, Springer Science + Business Media

    Dr Ana Maria Cuervo

  53. Lysosomal Proteolysis and Autophagy Require Presenilin 1 and Are Disrupted by Alzheimer-Related PS1 Mutations

    Article • Cell, June 2010, Elsevier

    Dr Ana Maria Cuervo

  54. Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease

    Article • Nature Neuroscience, April 2010, Springer Science + Business Media

    Dr Ana Maria Cuervo

  55. Chaperone-mediated autophagy: selectivity pays off

    Article • Trends in Endocrinology and Metabolism, March 2010, Elsevier

    Dr Ana Maria Cuervo

  56. Protein degradation, aggregation, and misfolding

    Article • Movement Disorders, January 2010, Wiley

    Dr Ana Maria Cuervo

  57. Chaperone-mediated autophagy in health and disease

    Article • FEBS Letters, December 2009, Wiley

    Dr Ana Maria Cuervo

  58. Lipases in lysosomes, what for?

    Article • Autophagy, August 2009, Taylor & Francis

    Dr Ana Maria Cuervo

  59. In search of an “autophagomometer”

    Article • Autophagy, July 2009, Taylor & Francis

    Dr Ana Maria Cuervo

  60. Autophagy regulates lipid metabolism

    Article • Nature, April 2009, Springer Science + Business Media

    Dr Ana Maria Cuervo

  61. Monomeric fluorescent timers that change color from blue to red report on cellular trafficking

    Article • Nature Chemical Biology, January 2009, Springer Science + Business Media

    Dr Ana Maria Cuervo

  62. Chapter 19 Methods to Monitor Chaperone‐Mediated Autophagy

    Article • January 2009, Elsevier

    Dr Ana Maria Cuervo

  63. Autophagy and aging: keeping that old broom working

    Article • Trends in Genetics, December 2008, Elsevier

    Dr Ana Maria Cuervo

  64. Entering the lysosome through a transient gate by chaperone-mediated autophagy

    Article • Autophagy, November 2008, Taylor & Francis

    Dr Ana Maria Cuervo

  65. Restoration of chaperone-mediated autophagy in aging liver improves cellular maintenance and hepatic function

    Article • Nature Reports Stem Cells, August 2008, Springer Science + Business Media

    Dr Ana Maria Cuervo

  66. Degradation of Proteasomes by Lysosomes in Rat Liver

    Article • European Journal of Biochemistry, June 2008, Wiley

    Dr Ana Maria Cuervo

  67. Early cellular changes after blockage of chaperone-mediated autophagy

    Article • Autophagy, May 2008, Taylor & Francis

    Dr Ana Maria Cuervo

  68. Autophagy fights disease through cellular self-digestion

    Article • Nature, February 2008, Springer Science + Business Media

    Dr Ana Maria Cuervo

  69. Dopamine-modified α-synuclein blocks chaperone-mediated autophagy

    Article • Journal of Clinical Investigation, January 2008, American Society for Clinical Investigation

    Dr Ana Maria Cuervo

  70. Selective Autophagy in the Pathogenesis of Parkinson's Disease

    Article • January 2008, Elsevier

    Dr Ana Maria Cuervo

  71. Autophagy and neurodegeneration

    Article • Current Neurology and Neuroscience Reports, September 2007, Springer Science + Business Media

    Dr Ana Maria Cuervo

  72. Chaperone-Mediated Autophagy and Aging: A Novel Regulatory Role of Lipids Revealed

    Article • Autophagy, July 2007, Taylor & Francis

    Dr Ana Maria Cuervo

  73. Methods for Monitoring Autophagy from Yeast to Human

    Article • Autophagy, May 2007, Taylor & Francis

    Dr Ana Maria Cuervo

  74. Autophagy and neurodegeneration: when the cleaning crew goes on strike

    Article • The Lancet Neurology, April 2007, Elsevier

    Dr Ana Maria Cuervo

  75. Chaperone-mediated autophagy in aging and neurodegeneration: Lessons from α-synuclein

    Article • Experimental Gerontology, January 2007, Elsevier

    Dr Ana Maria Cuervo

  76. Autophagy in neurons: it is not all about food

    Article • Trends in Molecular Medicine, October 2006, Elsevier

    Dr Ana Maria Cuervo

  77. Autophagy in Disease and Aging

    Article • August 2006, Wiley

    Dr Ana Maria Cuervo

  78. Lysosome membrane lipid microdomains: novel regulators of chaperone-mediated autophagy

    Article • The EMBO Journal, August 2006, Wiley

    Dr Ana Maria Cuervo

  79. Lysosomal Chat Maintains the Balance

    Article • Autophagy, July 2006, Taylor & Francis

    Dr Ana Maria Cuervo

  80. Oxidative Stress and Autophagy

    Article • Antioxidants & Redox Signaling, January 2006, Mary Ann Liebert Inc

    Dr Ana Maria Cuervo

  81. Chaperone‐Mediated Autophagy in Aging and Disease

    Article • January 2006, Elsevier

    Dr Ana Maria Cuervo

  82. Autophagy and Aging: The Importance of Maintaining "Clean" Cells

    Article • Autophagy, October 2005, Taylor & Francis

    Dr Ana Maria Cuervo

  83. Unifying Nomenclature for the Isoforms of the Lysosomal Membrane Protein LAMP-2

    Article • Traffic, August 2005, Wiley

    Dr Ana Maria Cuervo

  84. Protein degradation and aging

    Article • Experimental Gerontology, August 2005, Elsevier

    Dr Ana Maria Cuervo

  85. Autophagy: Many paths to the same end

    Article • Molecular and Cellular Biochemistry, August 2004, Springer Science + Business Media

    Dr Ana Maria Cuervo

  86. Autophagy: in sickness and in health

    Article • Trends in Cell Biology, February 2004, Elsevier

    Dr Ana Maria Cuervo

  87. Stimulatory effect of vitamin C on autophagy in glial cells

    Article • Journal of Neurochemistry, August 2002, Wiley

    Dr Ana Maria Cuervo

  88. When lysosomes get old☆

    Article • Experimental Gerontology, March 2000, Elsevier

    Dr Ana Maria Cuervo

  89. Direct lysosomal uptake of α2-microglobulin contributes to chemically induced nephropathy

    Article • Kidney International, February 1999, Elsevier

    Dr Ana Maria Cuervo

  90. Lysosomes, a meeting point of proteins, chaperones, and proteases

    Article • Journal of Molecular Medicine, December 1997, Springer Science + Business Media

    Dr Ana Maria Cuervo

  91. Degradation of Proteasomes by Lysosomes in Rat Liver

    Article • European Journal of Biochemistry, February 1995, Wiley

    Dr Ana Maria Cuervo

  92. Nerve conduction velocity decrease and synaptic transmission alterations in caffeine-treated rats

    Article • Neurotoxicology and Teratology, January 1994, Elsevier

    Dr Ana Maria Cuervo

  93. Protein Degradation and the Lysosomal System

    Article • Wiley

    Dr Ana Maria Cuervo

  94. Autophagy – The Liaison between the Lysosomal System and Cell Death

    Article • Cambridge University Press

    Dr Ana Maria Cuervo