All Stories

  1. Continuous expression of TOX safeguards exhausted CD8 T cell epigenetic fate
  2. TET2 regulates early and late transitions in exhausted CD8 + T cell differentiation and limits CAR T cell function
  3. TET2 regulates early and late transitions in exhausted CD8+T-cell differentiation and limits CAR T-cell function
  4. In vitro modeling of CD8 + T cell exhaustion enables CRISPR screening to reveal a role for BHLHE40
  5. The SWI/SNF chromatin remodeling complexes BAF and PBAF differentially regulate epigenetic transitions in exhausted CD8+ T cells
  6. Efficient engineering of human and mouse primary cells using peptide-assisted genome editing
  7. Shared and distinct biological circuits in effector, memory and exhausted CD8+ T cells revealed by temporal single-cell transcriptomics and epigenetics
  8. Proteomic profiling of MIS-C patients indicates heterogeneity relating to interferon gamma dysregulation and vascular endothelial dysfunction
  9. Immune checkpoint expression on HIV-specific CD4+ T cells and response to their blockade are dependent on lineage and function
  10. Signaling through FcγRIIA and the C5a-C5aR pathway mediates platelet hyperactivation in COVID-19
  11. Deep immune profiling of MIS-C demonstrates marked but transient immune activation compared with adult and pediatric COVID-19
  12. In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer
  13. Deep Immune Profiling of MIS-C demonstrates marked but transient immune activation compared to adult and pediatric COVID-19
  14. Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications
  15. Comprehensive mapping of immune perturbations associated with severe COVID-19
  16. Deep immune profiling of COVID-19 patients reveals patient heterogeneity and distinct immunotypes with implications for therapeutic interventions
  17. Single-cell characterization and quantification of translation-competent viral reservoirs in treated and untreated HIV infection
  18. Multiparametric characterization of rare HIV-infected cells using an RNA-flow FISH technique
  19. Visualizing HIV viral translation-competent reservoirs.
  20. Tumor-necrosis factor is a master of T cell exhaustion
  21. High-throughput detection of miRNAs and gene-specific mRNA at the single-cell level by flow cytometry
  22. Macrophage Infection via Selective Capture of HIV-1-Infected CD4+ T Cells
  23. Efficient macrophage infection by phagocytosis of dying HIV-1 -infected CD4+T cells