All Stories

  1. Self-supervised plasma proteomic representations for prospective disease prediction across varying protein availability
  2. CytoGate-Bench: an LLM benchmark for cross-panel cell gating in cytometry
  3. Continuous expression of TOX safeguards exhausted CD8 T cell epigenetic fate
  4. TET2 regulates early and late transitions in exhausted CD8 + T cell differentiation and limits CAR T cell function
  5. TET2 regulates early and late transitions in exhausted CD8+T-cell differentiation and limits CAR T-cell function
  6. In vitro modeling of CD8 + T cell exhaustion enables CRISPR screening to reveal a role for BHLHE40
  7. The SWI/SNF chromatin remodeling complexes BAF and PBAF differentially regulate epigenetic transitions in exhausted CD8+ T cells
  8. Efficient engineering of human and mouse primary cells using peptide-assisted genome editing
  9. Shared and distinct biological circuits in effector, memory and exhausted CD8+ T cells revealed by temporal single-cell transcriptomics and epigenetics
  10. Proteomic profiling of MIS-C patients indicates heterogeneity relating to interferon gamma dysregulation and vascular endothelial dysfunction
  11. Immune checkpoint expression on HIV-specific CD4+ T cells and response to their blockade are dependent on lineage and function
  12. Signaling through FcγRIIA and the C5a-C5aR pathway mediates platelet hyperactivation in COVID-19
  13. Deep immune profiling of MIS-C demonstrates marked but transient immune activation compared with adult and pediatric COVID-19
  14. In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer
  15. Deep Immune Profiling of MIS-C demonstrates marked but transient immune activation compared to adult and pediatric COVID-19
  16. Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications
  17. Comprehensive mapping of immune perturbations associated with severe COVID-19
  18. Deep immune profiling of COVID-19 patients reveals patient heterogeneity and distinct immunotypes with implications for therapeutic interventions
  19. Single-cell characterization and quantification of translation-competent viral reservoirs in treated and untreated HIV infection
  20. Multiparametric characterization of rare HIV-infected cells using an RNA-flow FISH technique
  21. Visualizing HIV viral translation-competent reservoirs.
  22. Tumor-necrosis factor is a master of T cell exhaustion
  23. High-throughput detection of miRNAs and gene-specific mRNA at the single-cell level by flow cytometry
  24. Macrophage Infection via Selective Capture of HIV-1-Infected CD4+ T Cells
  25. Efficient macrophage infection by phagocytosis of dying HIV-1 -infected CD4+T cells