All Stories

  1. Current Insights into Liver Fibrosis: Epidemiological Patterns, Etiopathogenesis, Clinical Correlates, and Research Agenda
  2. Mechanobiological feedback loops and quantitative decision thresholds in organ fibrosis: Translational principles for antifibrotic therapy
  3. Interorgan Crosstalk in MASLD: A Narrative Review
  4. Biliary barrier disruption and phosphatidylcholine deficiency in primary sclerosing cholangitis
  5. Impact of Menopause and Menopausal Hormone Therapy on Liver–Kidney–Metabolic Health
  6. Editorial: Stand up to stay healthy?
  7. Synchronizing obesity management with survodutide
  8. Pharmacological chemoprevention of hepatocellular carcinoma: hype, hope, or reality?
  9. Inter-Organ Crosstalk in MASLD: A Narrative Review
  10. Metabolic Rewiring in MASLD: From Disease Mechanisms to Precision Medicine
  11. The Liver Left Behind: GLP-1 Receptor Agonists and the Prospect of Metabolic Adjuvant Therapy After HCC Resection
  12. Metabolic Rewiring in MASLD: From Disease Mechanisms to Precision Medicine
  13. Sex differences in MASLD-related atherosclerosis: plaque phenotype, vascular dysfunction, and cardiovascular outcomes
  14. How Physiology and Pharmacology Shape Liver Regeneration: From Molecules and Cells to Trials
  15. Current Insights into Liver Fibrosis: Epidemiological Patterns, Etiopathogenesis, Clinical Correlates, and Research Agenda
  16. Physiopharmacology of Liver Regeneration from Molecules to Trials
  17. Repurposing Resmetirom to Suppress MASLD/MASH-HCC in the Dysmetabolic Era
  18. X-chromosome gene dosage shapes MASLD beyond sex hormones
  19. Lipids at the helm: a metabolic playbook for liver regeneration
  20. Burden of Liver Disease Among Individuals With Turner Syndrome and Klinefelter Syndrome: A Comprehensive Perspective
  21. Understanding liver and digestive diseases: a paved road to improve diagnosis, management, and treatment
  22. Treating obesity with GLP-1 RAs: does sex matter? A commentary on the meta-analysis by Yang et al. (J Diabetes 2025;17(3):e70063)
  23. Biological determinants and outcomes of sex discrepancies in MASLD
  24. Liver Fibrosis and the Risks of Impaired Cognition and Dementia: Mechanisms, Evidence, and Clinical Implications
  25. Mitochondrial medicine in obesity: a scoping review
  26. Obesity, Metabolic Dysfunction-Associated Steatotic Liver Disease and Hepatocellular Carcinoma: How Molecular Changes Impact Cellular Functions
  27. Drug treatment of MASH from none to (too) many options?
  28. Insulin Resistance at the Crossroads of Metabolic Inflammation, Cardiovascular Disease, Organ Failure and Cancer
  29. Liver Fibrosis and the Risks of Impaired Cognition and Dementia: Mechanisms, Evidence, and Clinical Implications
  30. Unraveling One-Carbon Metabolism in Metabolic Dysfunction-Associated Steatotic Liver Disease: Semaglutide Turns Metabolic Stress Into Metabolic Resilience
  31. Sex differences in alcohol-related liver disease, viral hepatitis, metabolic dysfunction-associated steatotic liver disease, and hepatocellular carcinoma
  32. Stopping SOAT1 sparks an immune attack on liver cancer: a metabolic-immune axis in hepatocellular carcinoma
  33. Semaglutide from Bench to Bedside: The Experimental Journey Towards a Transformative Therapy for Diabetes, Obesity and Metabolic Liver Disorders
  34. Insulin Resistance at the Crossroads of Metabolic Inflammation, Cardiovascular Disease, Organ Failure, and Cancer
  35. Semaglutide from Bench to Bedside: The Experimental Journey Towards a Transformative Therapy for Diabetes, Obesity and Metabolic Liver Disorders
  36. Sex Hormones and Metabolic Dysfunction-Associated Steatotic Liver Disease
  37. Tirzepatide in metabolic dysfunction-associated steatotic liver disease and steatohepatitis: a novel star on the horizon?
  38. PPARs in molecular pathogenesis and drug treatment of type 2 diabetes-related MASLD
  39. MASLD vs. MAFLD. A narrative review
  40. Food insecurity is an emerging risk factor for liver disease: a scoping review
  41. The Ovary–Liver Axis: Molecular Science and Epidemiology
  42. Widening research horizons on metabolic dysfunction-associated steatotic liver disease and cancer
  43. Metabolic dysfunction‐associated steatotic liver disease and sex‐specific risk of fatal and non‐fatal cardiovascular events: A meta‐analysis
  44. Liver and obesity: a narrative review
  45. Targeting duodenum to reverse MASLD
  46. Not all fat is alike in MASLD
  47. Abdominal Aortic Aneurysm and Liver Fibrosis: Clinical Evidence and Molecular Pathomechanisms
  48. Duodenal mucosa resurfacing: the endoscopic silver bullet against metabolic disorders?
  49. Abdominal Aortic Aneurysm and Liver Fibrosis. Clinical Evidence and Molecular Pathomechanics
  50. Cardiovascular Mortality in MASLD: A Matter of Fat. Caution in Interpreting Liver Fat Quantification in Populations With High Fibrosis Variability
  51. PNPLA3 as a driver of steatotic liver disease: navigating from pathobiology to the clinics via epidemiology
  52. Global burden of disease attributable to metabolic risk factors in adolescents and young adults aged 15–39, 1990–2021
  53. Liver fibrosis as a barometer of systemic health by gauging the risk of extrahepatic disease
  54. MASLD: predictive value for liver-related events and extra-hepatic complications
  55. Intravenous lactated Ringer’s solution alone and in combination with NSAIDs in prevention of post-ERCP acute pancreatitis: an updated systematic review
  56. Clinical features and long-term outcomes of patients diagnosed with MASLD, MAFLD, or both
  57. Copper and liver fibrosis in MASLD: the two-edged sword of copper deficiency and toxicity
  58. Editorial - Reflecting on three years of M&TOD - Where we are and where we are going
  59. From Hypothalamic Obesity to Metabolic Dysfunction-Associated Steatotic Liver Disease: Physiology Meets the Clinics via Metabolomics
  60. Liver fibrosis: More than meets the eye
  61. Does an Aspirin a Day Take the MASLD Away?
  62. Researchers call for more flexible editorial conduct rather than abruptly adopting only the new MASLD nomenclature
  63. PRO‐C3, liver fibrosis and CKD: The plot thickens
  64. Resmetirom: Finally, the Light at the End of the NASH Tunnel?
  65. Endpoints in NASH Clinical Trials: Are We Blind in One Eye?
  66. MASLD co-aggregates with HCC in families-names change, fa(c)ts remain
  67. Reactivation of latent hepatitis B infection during immunosuppressive therapy with guselkumab for plaque psoriasis: a case report
  68. Role of steatotic liver disease in prediction and prevention of cardiometabolic diseases
  69. The heterogeneity of metabolic syndrome presentation and challenges this causes in its pharmacological management: a narrative review focusing on principal risk modifiers
  70. Principles of risk stratification in nonalcoholic fatty liver disease. A narrative review emphasizing non-invasive strategies
  71. Iron depletion in “metabolic fatty liver syndromes”: a strong biological rationale with disappointing liver outcomes
  72. Shutting those revolving doors
  73. Extra-hepatic cancers in metabolic fatty liver syndromes
  74. Rewriting the natural history of MAFLD on the basis of cardiovascular risk assessment
  75. Digging the metabolic roots of NASH up
  76. Nonalcoholic Fatty Liver Disease and Chronic Kidney Disease: Epidemiology, Pathogenesis, and Clinical and Research Implications
  77. Metabolic mechanisms for and treatment of NAFLD or NASH occurring after liver transplantation
  78. Precision medicine in nonalcoholic fatty liver disease
  79. Metabolomic signature: one step forward in the process of obtaining NAFLD patients’ metabolic identity card
  80. Separating the apples from the oranges: from NAFLD heterogeneity to personalized medicine
  81. Back to the future: From the history of NAFLD to MAFLD to heterogeneity of disease
  82. How Much Vitamin D is Too Much? A Case Report and Review of the Literature
  83. Clearing hepatitis C virus with direct antiviral agents reduces cardiovascular events in patients with prediabetes. Commentary to Sasso and colleagues
  84. Perspectives on Precision Medicine Approaches to NAFLD Diagnosis and Management
  85. Renaming NAFLD to MAFLD: Could the LDE System Assist in This Transition?
  86. Glucagon-Like Peptide-1 Receptor Agonists for Treatment of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis: An Updated Meta-Analysis of Randomized Controlled Trials
  87. Liver Fibrosis Biomarkers Accurately Exclude Advanced Fibrosis and Are Associated with Higher Cardiovascular Risk Scores in Patients with NAFLD or Viral Chronic Liver Disease
  88. Precision medicine approaches in metabolic disorders and target organ damage: where are we now, and where are we going?
  89. Non-alcoholic fatty liver disease and risk of incident chronic kidney disease: an updated meta-analysis
  90. Semi-Quantitative Ultrasonographic Evaluation of NAFLD
  91. History of Nonalcoholic Fatty Liver Disease
  92. Perspectives of nonalcoholic fatty liver disease research: a personal point of view
  93. Sexual Dimorphism of NAFLD in Adults. Focus on Clinical Aspects and Implications for Practice and Translational Research
  94. NAFLD in Some Common Endocrine Diseases: Prevalence, Pathophysiology, and Principles of Diagnosis and Management
  95. A critical appraisal of the use of ultrasound in hepatic steatosis
  96. Statins and nonalcoholic fatty liver disease in the era of precision medicine: More friends than foes
  97. Pathogenesis of hypothyroidism-induced NAFLD: Evidence for a distinct disease entity?
  98. A round trip from nonalcoholic fatty liver disease to diabetes: molecular targets to the rescue?
  99. Telomere shortening: An innocent bystander at the crossroad of NASH with ageing and cardiometabolic risk?
  100. Do Nonalcoholic Fatty Liver Disease and Fetuin-A Play Different Roles in Symptomatic Coronary Artery Disease and Peripheral Arterial Disease?
  101. Hypertension, diabetes, atherosclerosis and NASH: Cause or consequence?
  102. NAFLD: Is There Anything New under the Sun?
  103. Ultrasonographic fatty liver indicator detects mild steatosis and correlates with metabolic/histological parameters in various liver diseases
  104. Nonalcoholic fatty liver disease and COPD. Are they mutually associated ?
  105. Metabolic concerns in aging HIV-infected persons
  106. NAFLD as a Sexual Dimorphic Disease: Role of Gender and Reproductive Status in the Development and Progression of Nonalcoholic Fatty Liver Disease and Inherent Cardiovascular Risk
  107. AISF position paper on nonalcoholic fatty liver disease (NAFLD): Updates and future directions
  108. NAFLD, Hepatotropic Viruses, and Cardiometabolic Risk
  109. “ Not all forms of NAFLD were created equal ”. Do metabolic syndrome-related NAFLD and PNPLA3 -related NAFLD exert a variable impact on the risk of early carotid atherosclerosis?
  110. Clinical features and natural history of cryptogenic cirrhosis compared to hepatitis C virus-related cirrhosis
  111. Nonalcoholic steatohepatitis heralding olmesartan-induced sprue-like enteropathy
  112. Non-alcoholic fatty liver disease and risk of incident cardiovascular disease: A meta-analysis
  113. Non-alcoholic fatty liver disease and risk of cardiovascular disease
  114. Alcohol and Steatosis: The Japanese Paradox
  115. Global epidemiology of nonalcoholic fatty liver disease: Meta-analytic assessment of prevalence, incidence, and outcomes
  116. Nonalcoholic fatty liver disease is associated with an almost twofold increased risk of incident type 2 diabetes and metabolic syndrome. Evidence from a systematic review and meta-analysis
  117. The independent predictors of non-alcoholic steatohepatitis and its individual histological features.
  118. Type 2 Diabetes in Non-Alcoholic Fatty Liver Disease and Hepatitis C Virus Infection—Liver: The “Musketeer” in the Spotlight
  119. A “systems medicine” approach to the study of non-alcoholic fatty liver disease
  120. The Role of Nuclear Receptors in the Pathophysiology, Natural Course, and Drug Treatment of NAFLD in Humans
  121. Relationship between Non-Alcoholic Fatty Liver Disease and Psoriasis: A Novel Hepato-Dermal Axis?
  122. Nonalcoholic Fatty Liver Disease Is Associated With Higher 1-year All-Cause Rehospitalization Rates in Patients Admitted for Acute Heart Failure
  123. Cardiovascular Disease and Myocardial Abnormalities in Nonalcoholic Fatty Liver Disease
  124. Fatty liver is associated with an increased risk of diabetes and cardiovascular disease - Evidence from three different disease models: NAFLD, HCV and HIV
  125. Gamma glutamyl transferase: A novel cardiovascular outfit for an old liver test
  126. Epidemiological modifiers of non-alcoholic fatty liver disease: Focus on high-risk groups
  127. Sofosbuvir-based therapy cures hepatitis C virus infection after prior treatment failures in a patient with concurrent lymphoma
  128. Evidence that non-alcoholic fatty liver disease and polycystic ovary syndrome are associated by necessity rather than chance: a novel hepato-ovarian axis?
  129. Nonalcoholic fatty liver disease and decreased bone mineral density: is there a link?
  130. Do ultrasonographic semiquantitative indices predict histological changes in NASH irrespective of steatosis extent?
  131. Nonalcoholic fatty liver disease: A precursor of the metabolic syndrome
  132. Role of ultrasound in the diagnosis and treatment of nonalcoholic fatty liver disease and its complications
  133. Diagnosis and management of cardiovascular risk in nonalcoholic fatty liver disease
  134. Primary lymphoma of the spleen mimicking simple benign cysts: contrast-enhanced ultrasonography and other imaging findings
  135. Inflammatory hepatocellular adenomatosis, metabolic syndrome, polycystic ovary syndrome and non-alcoholic steatohepatitis: Chance tetrad or association by necessity?
  136. Cardiovascular risk, lipidemic phenotype and steatosis. A comparative analysis of cirrhotic and non-cirrhotic liver disease due to varying etiology
  137. Chronic hepatitis C virus infection and atherosclerosis: Clinical impact and mechanisms
  138. Nonalcoholic fatty liver disease and aging: Epidemiology to management
  139. Pathogenesis and significance of hepatitis C virus steatosis: An update on survival strategy of a successful pathogen
  140. Risk of cardiovascular, cardiac and arrhythmic complications in patients with non-alcoholic fatty liver disease
  141. From NAFLD in clinical practice to answers from guidelines
  142. Use of procalcitonin for the differential diagnosis of fever in cancer patients: an observational study
  143. Short-term multidisciplinary non-pharmacological intervention is effective in reducing liver fat content assessed non-invasively in patients with nonalcoholic fatty liver disease (NAFLD)
  144. Relationship of Serum Fetuin-A Levels with Coronary Atherosclerotic Burden and NAFLD in Patients Undergoing Elective Coronary Angiography
  145. Cardiovascular and Systemic Risk in Nonalcoholic Fatty Liver Disease - Atherosclerosis as a Major Player in the Natural Course of NAFLD
  146. HCV treatment in patients with metabolic syndrome
  147. Liver and diabetes. A vicious circle
  148. Potential for statins in the chemoprevention and management of hepatocellular carcinoma
  149. Hepatocellular carcinoma in a patient treated with efalizumab for psoriasis
  150. If steatosis is the atherosclerosis of the liver, are statins the “aspirin” for steatosis?
  151. Ultrasonographic fatty liver indicator, a novel score which rules out NASH and is correlated with metabolic parameters in NAFLD
  152. Chronic HCV infection is a risk of atherosclerosis. Role of HCV and HCV-related steatosis
  153. Human Immunodeficiency Virus Is the Major Determinant of Steatosis and Hepatitis C Virus of Insulin Resistance in Virus-associated Fatty Liver Disease
  154. Metabolic alterations and chronic hepatitis C: treatment strategies
  155. Treatment of Atherogenic Liver Based on the Pathogenesis of Nonalcoholic Fatty Liver Disease: A Novel Approach to Reduce Cardiovascular Risk?
  156. Nonalcoholic fatty liver disease activity score and Brunt's pathologic criteria for the diagnosis of nonalcoholic steatohepatitis: What do they mean and do they agree?
  157. Is nonalcoholic steatohepatitis associated with a high-though-normal thyroid stimulating hormone level and lower cholesterol levels?
  158. Insulin resistance in nonalcoholic steatohepatitis: necessary but not sufficient – death of a dogma from analysis of therapeutic studies?
  159. Perspectives on cellular dysfunction in nonalcoholic steatohepatitis: a case of ‘multiorganelle failure’? Proceedings of a virtual workshop on nonalcoholic steatohepatitis
  160. Clinical physiology of NAFLD: a critical overview of pathogenesis and treatment
  161. Practice guidelines for the diagnosis and management of nonalcoholic fatty liver disease
  162. Nonalcoholic Fatty Liver Disease in HIV-Infected Persons: Epidemiology and the Role of Nucleoside Reverse Transcriptase Inhibitors
  163. Genetic polymorphisms in non-alcoholic fatty liver disease: Interleukin-6−174G/C polymorphism is associated with non-alcoholic steatohepatitis
  164. NAFLD and Cardiovascular Risk: Direct Evidence for the Tale of Two Ages
  165. Differential effect of oleic and palmitic acid on lipid accumulation and apoptosis in cultured hepatocytes
  166. Endocrine and liver interaction: the role of endocrine pathways in NASH
  167. Hepatitis C and diabetes: the inevitable coincidence?
  168. Fatty Liver and Carotid Intimal Thickening: A Tale of Two Ages?
  169. Hepatitis C Virus-Infected Patients Are ‘Spared’ from the Metabolic Syndrome but Not from Insulin Resistance. A Comparative Study of Nonalcoholic Fatty Liver Disease and Hepatitis C Virus-Related Steatosis
  170. The hepatitis C virus-associated dysmetabolic syndrome
  171. Statins in liver disease: A molehill, an iceberg, or neither?
  172. Do diabetes and obesity promote hepatic fibrosis in familial heterozygous hypobetalipoproteinemia?
  173. Is liver fat detrimental to vessels?: intersections in the pathogenesis of NAFLD and atherosclerosis
  174. Dysmetabolic changes associated with HCV: a distinct syndrome?
  175. The neck-liver axis. Madelung disease as further evidence for an impact of body fat distribution on hepatic histology
  176. Non-alcoholic fatty liver disease (NAFLD) and cardiovascular disease: An open question
  177. HCV and diabetes
  178. Is Cholangiocarcinoma Another Complication of Insulin Resistance: A Report of Three Cases
  179. Chicken or egg turned into head or belly
  180. ‘Endocrine NAFLD’ a hormonocentric perspective of nonalcoholic fatty liver disease pathogenesis
  181. 17beta-estradiol prevents cytotoxicity from hydrophobic bile acids in HepG2 and WRL-68 cell cultures
  182. Hepatitis C and steatosis: a reappraisal
  183. Statins and HCV: A complex issue
  184. Gender, fatty liver and GGT
  185. Hepatic steatosis and insulin resistance: Does etiology make a difference?
  186. Fatty liver, carotid disease and gallstones: A study of age-related associations
  187. Review article: hepatic steatosis and insulin resistance
  188. Review article: the metabolic syndrome and non-alcoholic fatty liver disease
  189. Gallstone disease in non-alcoholic fatty liver: Prevalence and associated factors
  190. Pediatric gallstone disease in familial hypobetalipoproteinemia
  191. Should Nonalcoholic Fatty Liver Disease Be Renamed?
  192. The wide spectrum of steatohepatitis
  193. Steatosis and hepatitis C virus: Mechanisms and significance for hepatic and extrahepatic disease
  194. Relative contribution of iron burden, HFE mutations, and insulin resistance to fibrosis in nonalcoholic fatty liver
  195. Non-Organ-Specific Autoantibodies in Nonalcoholic Fatty Liver Disease: Prevalence and Correlates
  196. Intestinal Wegener's granulomatosis in a patient with severe alpha-1-antitrypsin deficiency resulting from a unique combination of two deficiency alleles (PiZ and PiMProcida)
  197. Apolipoprotein synthesis in nonalcoholic steatohepatitis
  198. Growth hormone plasma levels in nonalcoholic fatty liver disease
  199. Of liver, whisky and plants: a requiem for colchicine in alcoholic cirrhosis?
  200. Growth hormone plasma levels in nonalcoholic fatty liver disease
  201. Fasting insulin and uric acid levels but not indices of iron metabolism are independent predictors of non-alcoholic fatty liver disease. A case-control study
  202. Is insulin resistance a pathogenic co-factor in hepatitis C virus-related disease and hepatocellular carcinoma?
  203. A study of fatty liver disease and plasma lipoproteins in a kindred with familial hypobetalipoproteinemia due to a novel truncated form of apolipoprotein B (APO B-54.5)
  204. Are there any sex differences in fatty liver? A study of glucose metabolism and body fat distribution
  205. Fatty Liver and Nonalcoholic Steatohepatitis. Where Do We Stand and Where Are We Going?
  206. Isolated jejunal Crohn's disease in a young adult presenting as fever of unknown origin
  207. Fatty liver in heterozygous hypobetalipoproteinemia caused by a novel truncated form of apolipoprotein B
  208. LETTER TO THE EDITOR
  209. LETTER TO THE EDITOR
  210. Are Routine Duodenal and Antral Biopsies Useful in the Management of “Functional” Dyspepsia?
  211. Right Colon Adenocarcinoma Presenting as Bacteroides fragilis Liver Abscesses
  212. Solitary Peutz-Jeghers Type Polyp of the Stomach
  213. Liver cirrhosis as A diabetogenic condition
  214. Familial history in IBD
  215. Lack of correlation between the laboratory findings and a series of steps in the clinical severity of chronic liver disease