All Stories

  1. Dietary protein source dictates the impact of obesogenic diets on hepatic steatosis and insulin resistance via carnitine-dependent regulation of acetyl-CoA carboxylase

    Article • June 2026, openRxiv

    Dr Alexandre Caron

  2. Proanthocyanidin‐Rich Cranberry Extract Lowers Glycemia in Established Obesity by Delaying Glucose Absorption

    Article • The FASEB Journal, June 2026, Wiley

    Dr Alexandre Caron

  3. Cold exposure remodels bile acid metabolism in a mouse strain- and tissue-specific manner

    Article • Biochemical Journal, April 2026, Portland Press Ltd.

    Dr Alexandre Caron

  4. Noradrenergic inhibition of definitive POMC neurons through direct and indirect mechanisms

    Article • Journal of Neuroendocrinology, March 2026, Wiley

    Dr Alexandre Caron

  5. Impact of nesting materials on energy balance in male C57BL/6J mice exposed to different ambient temperatures

    Article • AJP Endocrinology and Metabolism, February 2026, American Physiological Society

    Dr Alexandre Caron

  6. GLP-1 is not enough: can glucagon fill the energy expenditure gap?

    Article • Neuroendocrinology, February 2026, Karger Publishers

    Dr Alexandre Caron

  7. Thermoregulatory adaptations to cold in C3H/HeJ mice are independent of ADRB3 signaling

    Article • Scientific Reports, February 2026, Springer Science + Business Media

    Dr Alexandre Caron

  8. Integrative genetic and liver transcriptomic analyses identify TRIB1AL as a target for steatotic liver disease

    Article • The Journal of Clinical Endocrinology & Metabolism, February 2026, Endocrine Society

    Dr Alexandre Caron

  9. Galanin Inhibits Histaminergic Neurons via Galanin Receptor 1

    Article • eNeuro, February 2026, Society for Neuroscience

    Dr Alexandre Caron

  10. Ablation of Sympathetic Nerve-β3 Adrenergic Receptor-mediated Adipose Tissue Lipolysis Attenuates Alcohol-induced Liver Injury in Mice

    Article • Cellular and Molecular Gastroenterology and Hepatology, January 2026, Elsevier

    Dr Alexandre Caron

  11. Automated quantification of collagen proportionate area correlates with molecular and histological markers of fibrosis in CCl4-treated rats

    Article • Experimental and Molecular Pathology, December 2025, Elsevier

    Dr Alexandre Caron

  12. Loss of hepatic alpha-1b adrenoceptor exacerbates inflammation and stellate cell activation in diet-induced MASLD

    Article • AJP Gastrointestinal and Liver Physiology, November 2025, American Physiological Society

    Dr Alexandre Caron

  13. Topiramate Enhances GABAergic Tone to Orexigenic Neuropeptide Y/Agouti‐Related Peptide (NPY/AgRP) Neurons

    Article • Obesity, October 2025, Wiley

    Dr Alexandre Caron

  14. Cold Exposure Exacerbates Cardiac Dysfunction in a Model of Heart Failure with Preserved Ejection Fraction in Male and Female C57Bl/6J Mice

    Article • Biomedicines, August 2025, MDPI AG

    Dr Alexandre Caron

  15. Pharmaco-nutraceutical improvement of the response to obeticholic acid with omega-3 polyunsaturated fatty acids

    Article • Biochemical Journal, August 2025, Portland Press Ltd.

    Dr Alexandre Caron

  16. Cold Exposure Exacerbates Cardiac Dysfunction in a Model of Heart Failure with Preserved Ejection Fraction in Male and Female C57Bl/6J Mice

    Article • July 2025, MDPI AG

    Dr Alexandre Caron

  17. The long non-coding RNATRIB1ALlinks metabolic dysfunction-associated steatotic liver disease, cardiometabolic risk and human lifespan

    Article • June 2025, Cold Spring Harbor Laboratory Press

    Dr Alexandre Caron

  18. New players in the leptin orchestra: PNOC/NPY neurons tune appetite and obesity

    Article • Neuron, June 2025, Elsevier

    Dr Alexandre Caron

  19. Spontaneous and pharmacologically induced hypothermia protect mice against endotoxic shock

    Article • British Journal of Pharmacology, February 2025, Wiley

    Dr Alexandre Caron, Laurent Gautron

  20. Changes in hypothalamic subunits volume and their association with metabolic parameters and gastrointestinal appetite-regulating hormones following bariatric surgery

    Article • Imaging Neuroscience, January 2025, The MIT Press

    Dr Alexandre Caron

  21. Ablation of sympathetic nerve-β3 adrenergic receptor-mediated adipose tissue lipolysis attenuates alcohol-induced liver injury in mice

    Article • December 2024, Cold Spring Harbor Laboratory Press

    Dr Alexandre Caron

  22. Liver adrenoceptor alpha-1b plays a key role in energy and glucose homeostasis in female mice

    Article • AJP Endocrinology and Metabolism, November 2024, American Physiological Society

    Dr Alexandre Caron

  23. A sympathetic paradigm shift for the role of NPY in obesity

    Article • Cell Metabolism, November 2024, Elsevier

    Dr Alexandre Caron

  24. Changes in hypothalamic subunits volume and their association with metabolic parameters and gastrointestinal appetite-regulating hormones following bariatric surgery

    Article • August 2024, Cold Spring Harbor Laboratory Press

    Dr Alexandre Caron

  25. Unveiling a novel memory center in human brain: neurochemical identification of the nucleus incertus, a key pontine locus implicated in stress and neuropathology

    Article • Biological Research, July 2024, Springer Science + Business Media

    Dr Alexandre Caron

  26. HSDL2 links nutritional cues to bile acid and cholesterol homeostasis

    Article • Science Advances, May 2024, American Association for the Advancement of Science

    Dr Alexandre Caron

  27. The effects of the β1‐adrenergic receptor antagonist bisoprolol administration on mirabegron‐stimulated human brown adipose tissue thermogenesis

    Article • Acta Physiologica, March 2024, Wiley

    Dr Alexandre Caron

  28. Hypothalamic GABAergic Neurons Expressing Cellular Retinoic Acid Binding Protein 1 (CRABP1) Are Sensitive to Metabolic Status and Liraglutide in Male Mice

    Article • Neuroendocrinology, January 2024, Karger Publishers

    Dr Alexandre Caron

  29. Unveiling a Novel Memory Center in Humans: Neurochemical Identification of theNucleus Incertus, a Key Pontine Locus Implicated in Stress and Neuropathology

    Article • September 2023, Cold Spring Harbor Laboratory Press

    Dr Alexandre Caron

  30. Electrophysiological Comparison of Definitive Pro-opiomelanocortin Neurons in the Arcuate Nucleus and the Retrochiasmatic Area of Male and Female Mice

    Article • Neuroscience, August 2023, Elsevier

    Dr Alexandre Caron

  31. Histaminergic regulation of food intake

    Article • Frontiers in Endocrinology, June 2023, Frontiers

    Dr Alexandre Caron

  32. Inhibition of the beta-1 adrenergic receptor does not potentiate mirabegron-stimulated human brown adipose tissue thermogenesis.

    Article • March 2023, Cold Spring Harbor Laboratory Press

    Dr Alexandre Caron

  33. A Critical Update on the Leptin‐Melanocortin System

    Article • Journal of Neurochemistry, January 2023, Wiley

    Dr Alexandre Caron

  34. Photoperiodic Remodeling of Adiposity and Energy Metabolism in Non-Human Mammals

    Article • International Journal of Molecular Sciences, January 2023, MDPI AG

    Dr Alexandre Caron

  35. DEPTOR loss impairs brown adipocyte development in vitro but has limited impacts in mice

    Article • Molecular Metabolism, January 2023, Elsevier

    Dr Alexandre Caron

  36. The sympathetic nervous system in the 21st century: Neuroimmune interactions in metabolic homeostasis and obesity

    Article • Neuron, November 2022, Elsevier

    Dr Alexandre Caron

  37. Do POMC neurons have a sweet tooth for leptin? Special issue: Role of nutrients in nervous control of energy balance

    Article • Biochimie, September 2022, Elsevier

    Dr Alexandre Caron

  38. Pathophysiological Mechanisms That Alter the Autonomic Brain-Liver Communication in Metabolic Diseases

    Article • Endocrinology, August 2021, Endocrine Society

    Dr Alexandre Caron

  39. CB1Rs in VMH neurons regulate glucose homeostasis but not body weight

    Article • AJP Endocrinology and Metabolism, July 2021, American Physiological Society

    Dr Alexandre Caron

  40. New Horizons: Is Obesity a Disorder of Neurotransmission?

    Article • The Journal of Clinical Endocrinology & Metabolism, June 2021, Endocrine Society

    Dr Alexandre Caron

  41. Melanocortin regulation of histaminergic neurons via perifornical lateral hypothalamic melanocortin 4 receptors

    Article • Molecular Metabolism, May 2020, Elsevier

    Dr Alexandre Caron

  42. The Hepatokine TSK does not affect brown fat thermogenic capacity, body weight gain, and glucose homeostasis

    Article • Molecular Metabolism, December 2019, Elsevier

    Ph.D. William T Festuccia, Dr Alexandre Caron

  43. Partial Leptin Reduction as an Insulin Sensitization and Weight Loss Strategy

    Article • Cell Metabolism, October 2019, Elsevier

    Dr Alexandre Caron

  44. Adipocyte Gs but not Gi signaling regulates whole-body glucose homeostasis

    Article • Molecular Metabolism, September 2019, Elsevier

    Dr Alexandre Caron

  45. The hepatokine Tsukushi is released in response to NAFLD and impacts cholesterol homeostasis

    Article • JCI Insight, August 2019, American Society for Clinical Investigation

    Dr Alexandre Caron, Ph.D. William T Festuccia

  46. Identification of leptin receptor-expressing cells in the nodose ganglion of male mice

    Article • Endocrinology, March 2019, Endocrine Society

    Dr Alexandre Caron, Laurent Gautron

  47. PPARγ is a major regulator of branched-chain amino acid blood levels and catabolism in white and brown adipose tissues

    Article • Metabolism, December 2018, Elsevier

    Dr Alexandre Caron, Ph.D. William T Festuccia

  48. Interscapular brown adipose tissue denervation does not promote the oxidative activity of inguinal white adipose tissue in male mice

    Article • AJP Endocrinology and Metabolism, August 2018, American Physiological Society

    Dr Alexandre Caron, Ph.D. William T Festuccia

  49. DEPTOR at the Nexus of Cancer, Metabolism, and Immunity

    Article • Physiological Reviews, July 2018, American Physiological Society

    Dr Alexandre Caron

  50. POMC neurons expressing leptin receptors coordinate metabolic responses to fasting via suppression of leptin levels

    Article • eLife, March 2018, eLife

    Dr Alexandre Caron

  51. Loss of OcaB Prevents Age-Induced Fat Accretion and Insulin Resistance by Altering B-Lymphocyte Transition and Promoting Energy Expenditure

    Article • Diabetes, March 2018, American Diabetes Association

    Dr Alexandre Caron

  52. Leptin and brain–adipose crosstalks

    Article • Nature Reviews Neuroscience, February 2018, Nature

    Dr Alexandre Caron, Laurent Gautron

  53. Leptin Receptor Expression in Mouse Intracranial Perivascular Cells

    Article • Frontiers in Neuroanatomy, January 2018, Frontiers

    Dr Alexandre Caron, Laurent Gautron

  54. Desacetyl-α-melanocyte stimulating hormone and α-melanocyte stimulating hormone are required to regulate energy balance

    Article • Molecular Metabolism, November 2017, Elsevier

    Dr Alexandre Caron

  55. Loss of hepatic DEPTOR alters the metabolic transition to fasting

    Article • Molecular Metabolism, February 2017, Elsevier

    Dr Alexandre Caron

  56. Energy Homeostasis: Paraventricular Nucleus System☆

    Article • January 2017, Elsevier

    Dr Alexandre Caron

  57. Amplification of Adipogenic Commitment by VSTM2A

    Article • Cell Reports, January 2017, Elsevier

    Dr Alexandre Caron

  58. Loss of UCP2 impairs cold-induced non-shivering thermogenesis by promoting a shift toward glucose utilization in brown adipose tissue

    Article • Biochimie, January 2017, Elsevier

    Dr Alexandre Caron

  59. mTORC1 is Required for Brown Adipose Tissue Recruitment and Metabolic Adaptation to Cold

    Article • Scientific Reports, November 2016, Nature

    Dr Alexandre Caron, Ph.D. William T Festuccia

  60. Neuronal systems and circuits involved in the control of food intake and adaptive thermogenesis

    Article • Annals of the New York Academy of Sciences, October 2016, Wiley

    Dr Alexandre Caron, Denis Richard

  61. Metabolic activity of brown, “beige,” and white adipose tissues in response to chronic adrenergic stimulation in male mice

    Article • AJP Endocrinology and Metabolism, May 2016, American Physiological Society

    Dr Alexandre Caron

  62. DEPTOR in POMC neurons affects liver metabolism but is dispensable for the regulation of energy balance

    Article • AJP Regulatory Integrative and Comparative Physiology, April 2016, American Physiological Society

    Dr Alexandre Caron

  63. Involvement of the Acyl-CoA binding domain containing 7 in the control of food intake and energy expenditure in mice

    Article • eLife, February 2016, eLife

    Dr Alexandre Caron

  64. Mediobasal hypothalamic overexpression of DEPTOR protects against high-fat diet-induced obesity

    Article • Molecular Metabolism, February 2016, Elsevier

    Dr Alexandre Caron

  65. Hypothalamic control of brown adipose tissue thermogenesis

    Article • Frontiers in Systems Neuroscience, November 2015, Frontiers

    Dr Alexandre Caron

  66. mTOR and lipid metabolism

    Article • Annual Review of Nutrition, July 2015, Annual Reviews

    Dr Alexandre Caron, Denis Richard

  67. In vivo measurement of energy substrate contribution to cold-induced brown adipose tissue thermogenesis

    Article • The FASEB Journal, February 2015, Federation of American Societies For Experimental Biology (FASEB)

    Dr Alexandre Caron, Denis Richard

  68. A Mitofusin-2–dependent inactivating cleavage of Opa1 links changes in mitochondria cristae and ER contacts in the postprandial liver

    Article • Proceedings of the National Academy of Sciences, October 2014, Proceedings of the National Academy of Sciences

    Dr Alexandre Caron

  69. DEP domain-containing mTOR-interacting protein in the rat brain: Distribution of expression and potential implication

    Article • The Journal of Comparative Neurology, September 2014, Wiley

    Dr Alexandre Caron, Denis Richard

  70. The medial preoptic nucleus as a site of the thermogenic and metabolic actions of melanotan II in male rats

    Article • AJP Regulatory Integrative and Comparative Physiology, May 2014, American Physiological Society

    Dr Alexandre Caron

  71. Interrelationships between ghrelin, insulin and glucose homeostasis: Physiological relevance

    Article • World Journal of Diabetes, January 2014, Baishideng Publishing Group Co., Limited (formerly WJG Press)

    Dr Alexandre Caron

  72. Leptin resistance in obesity and aging

    Article • Clinical Interventions in Aging, July 2013, Taylor & Francis

    Dr Alexandre Caron, Denis Richard