All Stories

  1. Hypoxia couples growth and developmental timing by decoupling steroid synthesis and secretion

    Article • January 2026, openRxiv

    Alexander Shingleton

  2. Private QTLs and the Genetic Architecture of Hierarchical Size Traits: From Body Size to Sex-Specific Plasticity

    Article • October 2025, Cold Spring Harbor Laboratory Press

    Alexander Shingleton

  3. Dpp Scaling is Not the Key to Robust Wing Patterning in Drosophila

    Article • April 2025, Cold Spring Harbor Laboratory Press

    Alexander Shingleton

  4. HIF signaling in the prothoracic gland regulates growth and development in hypoxia but not normoxia in Drosophila

    Article • Journal of Experimental Biology, September 2024, The Company of Biologists

    Alexander Shingleton

  5. A dynamical model of growth and maturation in Drosophila

    Article • Proceedings of the National Academy of Sciences, November 2023, Proceedings of the National Academy of Sciences

    Alexander Shingleton, Professor John J Tyson

  6. Genetic Variation in Sexual Size Dimorphism Is Associated with Variation in Sex-Specific Plasticity in Drosophila

    Article • The American Naturalist, September 2023, University of Chicago Press

    Alexander Shingleton

  7. Genetic variation of morphological scaling in Drosophila melanogaster

    Article • Heredity, March 2023, Springer Science + Business Media

    Alexander Shingleton

  8. Sex-specific regulation of development, growth and metabolism

    Article • Seminars in Cell and Developmental Biology, March 2023, Elsevier

    Alexander Shingleton

  9. The steroid hormone ecdysone regulates growth rate in response to oxygen availability

    Article • Scientific Reports, March 2022, Springer Science + Business Media

    Alexander Shingleton

  10. Ecdysone coordinates plastic growth with robust pattern in the developing wing

    Article • eLife, March 2022, eLife

    Alexander Shingleton

  11. Sex-specific plasticity and the nutritional geometry of insulin-signaling gene expression in Drosophila melanogaster

    Article • EvoDevo, May 2021, Springer Science + Business Media

    Alexander Shingleton

  12. Network‐regulated organ allometry: The developmental regulation of morphological scaling

    Article • Wiley Interdisciplinary Reviews Developmental Biology, June 2020, Wiley

    Alexander Shingleton

  13. Individual Cryptic Scaling Relationships and the Evolution of Animal Form

    Article • Integrative and Comparative Biology, July 2019, Oxford University Press (OUP)

    Alexander Shingleton, Dr Gerald S Wilkinson

  14. Which Line to Follow? The Utility of Different Line-Fitting Methods to Capture the Mechanism of Morphological Scaling

    Article • Integrative and Comparative Biology, May 2019, Oxford University Press (OUP)

    Alexander Shingleton

  15. Insulin-insensitivity of male genitalia maintains reproductive success in Drosophila

    Article • Biology Letters, May 2019, Royal Society Publishing

    Alexander Shingleton

  16. Coordinating Development: How Do Animals Integrate Plastic and Robust Developmental Processes?

    Article • Frontiers in Cell and Developmental Biology, February 2019, Frontiers

    Alexander Shingleton

  17. Plasticity Through Canalization: The Contrasting Effect of Temperature on Trait Size and Growth in Drosophila

    Article • Frontiers in Cell and Developmental Biology, November 2018, Frontiers

    Alexander Shingleton

  18. The (ongoing) problem of relative growth

    Article • Current Opinion in Insect Science, February 2018, Elsevier

    Alexander Shingleton

  19. The sex-specific effects of diet quality versus quantity on morphology in Drosophila melanogaster

    Article • Royal Society Open Science, September 2017, Royal Society Publishing

    Dr Christen Kerry Mirth, Alexander Shingleton

  20. Quantifying Abdominal Pigmentation in Drosophila melanogaster

    Article • Journal of Visualized Experiments, June 2017, MyJove Corporation

    Alexander Shingleton

  21. Intra-organ growth coordination in Drosophila is mediated by systemic ecdysone signaling

    Article • Developmental Biology, October 2016, Elsevier

    Alexander Shingleton

  22. Cryptic individual scaling relationships and the evolution of morphological scaling

    Article • Evolution, July 2016, Wiley

    Alexander Shingleton

  23. Allometry and size control: what can studies of body size regulation teach us about the evolution of morphological scaling relationships?

    Article • Current Opinion in Insect Science, February 2016, Elsevier

    Dr Christen Kerry Mirth, Alexander Shingleton

  24. Tipping the scales: Evolution of the allometric slope independent of average trait size

    Article • Evolution, February 2016, Wiley

    Alexander Shingleton

  25. Stunted by Developing in Hypoxia: Linking Comparative and Model Organism Studies

    Article • Physiological and Biochemical Zoology, September 2015, University of Chicago Press

    Alexander Shingleton

  26. Physiology: Female Flies Have the Guts for Reproduction

    Article • Current Biology, August 2015, Elsevier

    Alexander Shingleton

  27. Ecdysone promotes growth of imaginal discs through the regulation of Thor in D. melanogaster

    Article • Scientific Reports, July 2015, Nature

    Dr Christen Kerry Mirth, Alexander Shingleton

  28. Size control: the developmental physiology of body and organ size regulation

    Article • Wiley Interdisciplinary Reviews Developmental Biology, March 2015, Wiley

    Alexander Shingleton

  29. Nutritional control of body size through FoxO-Ultraspiracle mediated ecdysone biosynthesis

    Article • eLife, November 2014, eLife

    Dr Christen Kerry Mirth, Alexander Shingleton

  30. Mitochondrial chaperone TRAP1 activates the mitochondrial UPR and extends healthspan in Drosophila

    Article • Mechanisms of Ageing and Development, November 2014, Elsevier

    Alexander Shingleton

  31. The roles of juvenile hormone, insulin/target of rapamycin, and ecydsone signaling in regulating body size inDrosophila

    Article • Communicative & Integrative Biology, October 2014, Taylor & Francis

    Dr Christen Kerry Mirth, Alexander Shingleton

  32. Coordination of Wing and Whole-Body Development at Developmental Milestones Ensures Robustness against Environmental and Physiological Perturbations

    Article • PLoS Genetics, June 2014, PLOS

    Dr Christen Kerry Mirth, Alexander Shingleton

  33. Juvenile hormone regulates body size and perturbs insulin signaling in Drosophila

    Article • Proceedings of the National Academy of Sciences, April 2014, Proceedings of the National Academy of Sciences

    Dr Christen Kerry Mirth, Alexander Shingleton, Professor Lynn Moorhead Riddiford

  34. The role of reduced oxygen in the developmental physiology of growth and metamorphosis initiation in Drosophila melanogaster

    Article • Journal of Experimental Biology, November 2013, The Company of Biologists

    Dr Shampa M Ghosh, Alexander Shingleton

  35. The developmental control of size in insects

    Article • Wiley Interdisciplinary Reviews Developmental Biology, July 2013, Wiley

    Dr Christen Kerry Mirth, Alexander Shingleton, Professor Lynn Moorhead Riddiford

  36. New Frontiers for Organismal Biology

    Article • BioScience, June 2013, Oxford University Press (OUP)

    Alexander Shingleton

  37. Temperature-size rule is mediated by thermal plasticity of critical size in Drosophila melanogaster

    Article • Proceedings of the Royal Society B Biological Sciences, April 2013, Royal Society Publishing

    Dr Shampa M Ghosh, Alexander Shingleton

  38. Growth regulation and the insulin signaling pathway

    Article • Networks & Heterogeneous Media, April 2013, American Institute of Mathematical Sciences (AIMS)

    Alexander Shingleton

  39. Sex-Specific Weight Loss Mediates Sexual Size Dimorphism in Drosophila melanogaster

    Article • PLOS One, March 2013, PLOS

    Dr Shampa M Ghosh, Alexander Shingleton

  40. New perspectives on the evolution of exaggerated traits

    Article • BioEssays, December 2012, Wiley

    Alexander Shingleton

  41. Plastic flies

    Article • Fly, July 2012, Taylor & Francis

    Alexander Shingleton

  42. Integrating Body and Organ Size in Drosophila: Recent Advances and Outstanding Problems

    Article • Frontiers in Endocrinology, January 2012, Frontiers

    Dr Christen Kerry Mirth, Alexander Shingleton

  43. The Effect of Genetic and Environmental Variation on Genital Size in Male Drosophila: Canalized but Developmentally Unstable

    Article • PLOS One, December 2011, PLOS

    Alexander Shingleton

  44. FOXO Regulates Organ-Specific Phenotypic Plasticity In Drosophila

    Article • PLoS Genetics, November 2011, PLOS

    Alexander Shingleton

  45. Experimental Manipulation of Body Size to Estimate Morphological Scaling Relationships in Drosophila

    Article • Journal of Visualized Experiments, October 2011, MyJove Corporation

    Alexander Shingleton

  46. The coordination of growth among Drosophila organs in response to localized growth-perturbation

    Article • Developmental Biology, September 2011, Elsevier

    Alexander Shingleton

  47. The regulation of organ size in Drosophila

    Article • Organogenesis, April 2010, Taylor & Francis

    Alexander Shingleton

  48. The effects of molar tooth involvement in mandibular angle fractures treated with rigid fixation

    Article • Otolaryngology, June 2009, SAGE Publications

    Alexander Shingleton

  49. Many ways to be small: different environmental regulators of size generate distinct scaling relationships in Drosophila melanogaster

    Article • Proceedings of the Royal Society B Biological Sciences, April 2009, Royal Society Publishing

    Alexander Shingleton

  50. Imaginal discs regulate developmental timing in Drosophila melanogaster

    Article • Developmental Biology, September 2008, Elsevier

    Alexander Shingleton

  51. Developmental model of static allometry in holometabolous insects

    Article • Proceedings of the Royal Society B Biological Sciences, August 2008, Royal Society Publishing

    Dr Christen Kerry Mirth, Alexander Shingleton

  52. The effects of laser irradiation on Trichophyton rubrum growth

    Article • Lasers in Medical Science, September 2007, Springer Science + Business Media

    Alexander Shingleton

  53. Size and shape: the developmental regulation of static allometry in insects

    Article • BioEssays, January 2007, Wiley

    Professor Douglas J Emlen, Alexander Shingleton

  54. Body-Size Regulation: Combining Genetics and Physiology

    Article • Current Biology, October 2005, Elsevier

    Alexander Shingleton

  55. The Temporal Requirements for Insulin Signaling During Development in Drosophila

    Article • PLoS Biology, August 2005, PLOS

    Alexander Shingleton

  56. THE ORIGIN OF A MUTUALISM: A MORPHOLOGICAL TRAIT PROMOTING THE EVOLUTION OF ANT-APHID MUTUALISMS

    Article • Evolution, April 2005, Wiley

    Alexander Shingleton

  57. Developmental Origin and Evolution of Bacteriocytes in the Aphid–Buchnera Symbiosis

    Article • PLoS Biology, October 2003, PLOS

    Alexander Shingleton

  58. Size-correlated division of labour and spatial distribution of workers in the driver ant, Dorylus molestus

    Article • The Science of Nature, June 2003, Springer Science + Business Media

    Alexander Shingleton

  59. A comparison of parthenogenetic and sexual embryogenesis of the pea aphidAcyrthosiphon pisum (Hemiptera: Aphidoidea)

    Article • The Journal of Experimental Zoology, January 2003, Wiley

    Alexander Shingleton

  60. Article • BMC Developmental Biology, January 2003, Springer Science + Business Media

    Alexander Shingleton

  61. Molecular phylogenetic evidence for multiple gains or losses of ant mutualism within the aphid genus Chaitophorus

    Article • Molecular Phylogenetics and Evolution, January 2003, Elsevier

    Alexander Shingleton

  62. Behaviour, morphology and the division of labour in two soldier-producing aphids

    Article • Animal Behaviour, October 2001, Elsevier

    Alexander Shingleton

  63. Host plant and ants influence the honeydew sugar composition of aphids

    Article • Functional Ecology, August 2001, Wiley

    Alexander Shingleton

  64. Ant tending influences soldier production in a social aphid

    Article • Proceedings of the Royal Society B Biological Sciences, September 2000, Royal Society Publishing

    Alexander Shingleton