All Stories

  1. Structures of a calcium channel reveal crosstalk of intracellular segments
  2. A peptide toxin in ant venom mimics vertebrate EGF-like hormones to cause long-lasting hypersensitivity in mammals
  3. Multitarget nociceptor sensitization by a promiscuous peptide from the venom of the King Baboon spider
  4. A pain-causing and paralytic ant venom glycopeptide
  5. Vincristine-induced peripheral neuropathy is driven by canonical NLRP3 activation and IL-1β release
  6. Subcutaneous ω-Conotoxins Alleviate Mechanical Pain in Rodent Models of Acute Peripheral Neuropathy
  7. Small cyclic sodium channel inhibitors
  8. Recombinant production, bioconjugation and membrane binding studies of Pn3a, a selective NaV1.7 inhibitor
  9. Manipulation of a spider peptide toxin alters its affinity for lipid bilayers and potency and selectivity for voltage-gated sodium channel subtype 1.7
  10. Mapping the Molecular Surface of the Analgesic NaV1.7-Selective Peptide Pn3a Reveals Residues Essential for Membrane and Channel Interactions
  11. Minocycline Prevents the Development of Mechanical Allodynia in Mouse Models of Vincristine-Induced Peripheral Neuropathy
  12. Inflammatory and Neuropathic Gene Expression Signatures of Chemotherapy-Induced Neuropathy Induced by Vincristine, Cisplatin, and Oxaliplatin in C57BL/6J Mice
  13. The tarantula venom peptide Pn3a effectively and safely reduces pain after surgery in mice
  14. A comprehensive portrait of the venom of the giant red bull ant, Myrmecia gulosa, reveals a hyperdiverse hymenopteran toxin gene family
  15. Abstracts
  16. The pharmacology of voltage-gated sodium channel activators
  17. Fluorescent Labeling and 2-Photon Imaging of Mouse Tooth Pulp Nociceptors
  18. NaV1.7 as a pain target – from gene to pharmacology
  19. Comprehensive thermal preference phenotyping in mice using a novel automated circular gradient assay
  20. α-conotoxin MrIC is a biased agonist at α7 nicotinic acetylcholine receptors
  21. Engineering an optimized analgesic from the NaV1.7 selective spider venom peptide Pn3a