All Stories

  1. Site-Specific Load-Induced Expansion of Sca-1+ Prrx1 + and Sca-1 − Prrx1 + Cells in Adult Mouse Long Bone Is Attenuated With Age

    Article • JBMR Plus, July 2019, Wiley

    Dr Alesha B Castillo

  2. Mechanical Loading Promotes the Expansion of Primitive Osteoprogenitors and Organizes Matrix and Vascular Morphology in Long Bone Defects

    Article • Journal of Bone and Mineral Research, February 2019, Wiley

    Dr Alesha B Castillo

  3. Author Correction: WNT-activated bone grafts repair osteonecrotic lesions in aged animals

    Article • Scientific Reports, April 2018, Springer Science + Business Media

    Dr Alesha B Castillo

  4. Targeting Osteogenesis-Angiogenesis Coupling for Bone Repair

    Article • Journal of the American Academy of Orthopaedic Surgeons, April 2018, Wolters Kluwer Health

    Dr Alesha B Castillo

  5. Effects of mechanical loading on cortical defect repair using a novel mechanobiological model of bone healing

    Article • Bone, March 2018, Elsevier

    Dr Alesha B Castillo

  6. Use of Ferrule Rings as Stress Dissipators in Temporomandibular Joint Intramedullary Implants: A Finite Element Analysis Study

    Article • Journal of Long-Term Effects of Medical Implants, January 2018, Begell House

    Dr Alesha B Castillo

  7. Nanotopographic Regulation of Human Mesenchymal Stem Cell Osteogenesis

    Article • ACS Applied Materials & Interfaces, November 2017, American Chemical Society (ACS)

    Dr Alesha B Castillo

  8. WNT-activated bone grafts repair osteonecrotic lesions in aged animals

    Article • Scientific Reports, October 2017, Springer Science + Business Media

    Dr Alesha B Castillo

  9. The Selective Serotonin Reuptake Inhibitor Fluoxetine Directly Inhibits Osteoblast Differentiation and Mineralization During Fracture Healing in Mice

    Article • Journal of Bone and Mineral Research, February 2017, Wiley

    Dr Alesha B Castillo

  10. Osteoblast-derived paracrine factors regulate angiogenesis in response to mechanical stimulation

    Article • Integrative Biology, January 2016, Oxford University Press (OUP)

    Dr Alesha B Castillo

  11. Mechanical loading causes site-specific anabolic effects on bone following exposure to ionizing radiation

    Article • Bone, December 2015, Elsevier

    Dr Alesha B Castillo

  12. Introduction for the special issue: Fracture healing and bone regeneration

    Article • Clinical Reviews in Bone and Mineral Metabolism, November 2015, Springer Science + Business Media

    Dr Alesha B Castillo

  13. Bone Homeostasis and Repair: Forced Into Shape

    Article • Current Rheumatology Reports, August 2015, Springer Science + Business Media

    Dr Alesha B Castillo

  14. Oxygen-sensing PHDs regulate bone homeostasis through the modulation of osteoprotegerin

    Article • Genes & Development, April 2015, Cold Spring Harbor Laboratory Press

    Dr Alesha B Castillo

  15. Comparison of three methods of calculating strain in the mouse ulna in exogenous loading studies

    Article • Journal of Biomechanics, January 2015, Elsevier

    Dr Alesha B Castillo

  16. Estrogen receptor-β regulates mechanical signaling in primary osteoblasts

    Article • AJP Endocrinology and Metabolism, April 2014, American Physiological Society

    Dr Alesha B Castillo

  17. Decellularized Tendon-Bone Composite Grafts for Extremity Reconstruction

    Article • Plastic & Reconstructive Surgery, January 2014, Wolters Kluwer Health

    Dr Alesha B Castillo

  18. Geometric mouse variation: Implications to the axial ulnar loading protocol and animal specific calibration

    Article • Journal of Biomechanics, September 2013, Elsevier

    Dr Alesha B Castillo

  19. CXCR4 antagonism attenuates load-induced periosteal bone formation in mice

    Article • Journal of Orthopaedic Research®, July 2013, Wiley

    Dr Alesha B Castillo

  20. Comparison of tricalcium phosphate cement and cancellous autograft as bone void filler in acetabular fractures with marginal impaction

    Article • Injury, July 2013, Elsevier

    Dr Alesha B Castillo

  21. Physicochemical Decellularization of Composite Flexor Tendon–Bone Interface Grafts

    Article • Plastic & Reconstructive Surgery, July 2013, Wolters Kluwer Health

    Dr Alesha B Castillo

  22. Wnt3a Reestablishes Osteogenic Capacity to Bone Grafts from Aged Animals

    Article • Journal of Bone and Joint Surgery, July 2013, The Journal of Bone and Joint Surgery, Inc.

    Dr Alesha B Castillo

  23. Cellular and Molecular Mechanotransduction in Bone

    Article • January 2013, Elsevier

    Dr Alesha B Castillo

  24. Focal Adhesion Kinase Plays a Role in Osteoblast Mechanotransduction In Vitro but Does Not Affect Load-Induced Bone Formation In Vivo

    Article • PLoS ONE, September 2012, PLOS

    Dr Alesha B Castillo

  25. Mechanosensing by the Primary Cilium: Deletion of Kif3A Reduces Bone Formation Due to Loading

    Article • PLoS ONE, March 2012, PLOS

    Dr Alesha B Castillo

  26. Skeletal Mechanobiology

    Article • March 2011, Taylor & Francis

    Dr Alesha B Castillo

  27. Mechanobiology Handbook

    Article • March 2011, Taylor & Francis

    Dr Alesha B Castillo

  28. The epigenetic mechanism of mechanically induced osteogenic differentiation

    Article • Journal of Biomechanics, November 2010, Elsevier

    Dr Alesha B Castillo

  29. Osteocyte Mechanobiology and Pericellular Mechanics

    Article • Annual Review of Biomedical Engineering, July 2010, Annual Reviews

    Dr Alesha B Castillo

  30. Mesenchymal Stem Cell Mechanobiology

    Article • Current Osteoporosis Reports, April 2010, Springer Science + Business Media

    Dr Alesha B Castillo

  31. Grizzly bears (Ursus arctos horribilis) and black bears (Ursus americanus) prevent trabecular bone loss during disuse (hibernation)

    Article • Bone, December 2009, Elsevier

    Dr Alesha B Castillo

  32. Deletion of β1 Integrins from Cortical Osteocytes Reduces Load-Induced Bone Formation

    Article • Cellular and Molecular Bioengineering, July 2009, Springer Science + Business Media

    Dr Alesha B Castillo

  33. Grizzly Bears ( Ursus Arctos Horribilis ) and Black Bears ( Ursus Americanus ) Prevent Trabecular Bone Loss During Disuse (Hibernation)

    Article • June 2009, ASME International

    Dr Alesha B Castillo

  34. Primary Cilia: Cellular Sensors for the Skeleton

    Article • The Anatomical Record, September 2008, Wiley

    Dr Alesha B Castillo

  35. The skeletal responsiveness to mechanical loading is enhanced in mice with a null mutation in estrogen receptor-β

    Article • AJP Endocrinology and Metabolism, August 2007, American Physiological Society

    Dr Alesha B Castillo

  36. Simulated effects of marathon training on bone density, remodeling, and microdamage accumulation of the femur

    Article • International Journal of Fatigue, June 2007, Elsevier

    Dr Alesha B Castillo

  37. Estrogen Receptor-Beta Regulates Mechanical Signaling in Primary Osteoblasts

    Article • Medicine & Science in Sports & Exercise, May 2007, Wolters Kluwer Health

    Dr Alesha B Castillo

  38. Exercise When Young Provides Lifelong Benefits to Bone Structure and Strength

    Article • Journal of Bone and Mineral Research, November 2006, Wiley

    Dr Alesha B Castillo

  39. Low-amplitude, broad-frequency vibration effects on cortical bone formation in mice

    Article • Bone, November 2006, Elsevier

    Dr Alesha B Castillo

  40. BIOMECHANICAL AND MOLECULAR REGULATION OF BONE REMODELING

    Article • Annual Review of Biomedical Engineering, August 2006, Annual Reviews

    Dr Alesha B Castillo

  41. Exercise During Growth Has Long-Term Benefits to Skeletal Health

    Article • Medicine & Science in Sports & Exercise, May 2006, Wolters Kluwer Health

    Dr Alesha B Castillo

  42. Knee ligament mechanical properties are not influenced by estrogen or its receptors

    Article • AJP Endocrinology and Metabolism, May 2006, American Physiological Society

    Dr Alesha B Castillo

  43. Biological Effects of Short-Term or Prolonged Administration of 9-[2-(Phosphonomethoxy)Propyl]Adenine (Tenofovir) to Newborn and Infant Rhesus Macaques

    Article • Antimicrobial Agents and Chemotherapy, June 2004, ASM Journals

    Dr Alesha B Castillo

  44. Tenofovir treatment at 30 mg/kg/day can inhibit cortical bone mineralization in growing rhesus monkeys (Macaca mulatta)

    Article • Journal of Orthopaedic Research®, November 2002, Wiley

    Dr Alesha B Castillo

  45. Fetal and Maternal Outcome After Administration of Tenofovir to Gravid Rhesus Monkeys (Macaca mulatta)

    Article • JAIDS Journal of Acquired Immune Deficiency Syndromes, March 2002, Wolters Kluwer Health

    Dr Alesha B Castillo

  46. Fetal and Maternal Outcome After Administration of Tenofovir to Gravid Rhesus Monkeys (Macaca mulatta)

    Article • JAIDS Journal of Acquired Immune Deficiency Syndromes, March 2002, Wolters Kluwer Health

    Dr Alesha B Castillo