All Stories

  1. Development and Validation of a Higher-Throughput Cytochrome P450 Inhibition Assay with the Novel Cofactor-Supplemented Permeabilized Cryopreserved Human Hepatocytes (MetMax Human Hepatocytes)

    Article • Drug Metabolism and Disposition, August 2019, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Albert Li

  2. A Novel In vitro Experimental System for the Evaluation of Enteric Drug Metabolism: Cofactor-Supplemented Permeabilized Cryopreserved Human Enterocytes (MetMax™ Cryopreserved Human Enterocytes)

    Article • Drug Metabolism Letters, November 2018, Bentham Science Publishers

    Albert Li

  3. Comparison of uptake transporter functions in hepatocytes in different species to determine the optimal model for evaluating drug transporter activities in humans

    Article • Xenobiotica, September 2018, Taylor & Francis

    Albert Li

  4. Cryopreserved Human Intestinal Mucosal Epithelium: A Novel In Vitro Experimental System for the Evaluation of Enteric Drug Metabolism, Cytochrome P450 Induction, and Enterotoxicity

    Article • Drug Metabolism and Disposition, July 2018, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Albert Li

  5. A Novel In Vitro Experimental System for the Evaluation of Drug Metabolism: Cofactor-Supplemented Permeabilized Cryopreserved Human Hepatocytes (MetMax Cryopreserved Human Hepatocytes)

    Article • Drug Metabolism and Disposition, January 2018, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Albert Li

  6. Human Enterocytes as an In Vitro Model for the Evaluation of Intestinal Drug Metabolism: Characterization of Drug-Metabolizing Enzyme Activities of Cryopreserved Human Enterocytes from Twenty-Four Donors

    Article • Drug Metabolism and Disposition, April 2017, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Albert Li

  7. Editorial: Promising approaches to identify DILI drugs

    Article • Chemico-Biological Interactions, August 2016, Elsevier

    Albert Li

  8. Meet Our Editorial Board Member

    Article • Current Drug Metabolism, January 2016, Bentham Science Publishers

    Albert Li

  9. Meet Our Editorial Board Member:

    Article • Drug Metabolism Letters, October 2015, Bentham Science Publishers

    Albert Li

  10. Cryopreservation of Hepatocytes

    Article • November 2014, Springer Science + Business Media

    Albert Li

  11. Evaluation of Human Hepatocytes Under Prolonged Culture in a Novel Medium for the Maintenance of Hepatic Differentiation: Results with the Model Pro-inflammatory Cytokine Interleukin 6

    Article • Drug Metabolism Letters, September 2014, Bentham Science Publishers

    Albert Li

  12. Application of a Higher Throughput Approach to Derive Apparent Michaelis-Menten Constants of Isoform-Selective P450-Mediated Biotransformation Reactions in Human Hepatocytes

    Article • Drug Metabolism Letters, June 2014, Bentham Science Publishers

    Albert Li

  13. In Vitro Human Hepatocyte-Based Experimental Systems for the Evaluation of Human Drug Metabolism, Drug-Drug Interactions, and Drug Toxicity in Drug Development

    Article • Current Topics in Medicinal Chemistry, June 2014, Bentham Science Publishers

    Albert Li

  14. Biomarkers and human hepatocytes

    Article • Biomarkers in Medicine, February 2014, Future Medicine

    Albert Li

  15. In VitroEvaluation of Metabolic Drug-Drug Interactions: Scientific Concepts and Practical Considerations

    Article • March 2010, Wiley

    Albert Li

  16. Enzyme Inhibition in Drug Discovery and Development

    Article • December 2009, Wiley

    Albert Li

  17. Overview: Evaluation of metabolism-based drug toxicity in drug development

    Article • Chemico-Biological Interactions, April 2009, Elsevier

    Albert Li

  18. Drug–Drug Interactions in Pharmaceutical Development

    Article • October 2007, Wiley

    Albert Li

  19. Human-Based In Vitro Experimental Systems for the Evaluation of Human Drug Safety

    Article • Current Drug Safety, September 2007, Bentham Science Publishers

    Albert Li

  20. In Vitro Evaluation of Metabolic Drug-Drug Interactions: Scientific Concepts and Practical Considerations

    Article • August 2007, Wiley

    Albert Li

  21. In Vitro Evaluation of Metabolic Drug-Drug Interactions: A Descriptive and Critical Commentary

    Article • August 2007, Wiley

    Albert Li

  22. Hepatocytes and drug development

    Article • Chemico-Biological Interactions, May 2007, Elsevier

    Albert Li

  23. Human hepatocytes: Isolation, cryopreservation and applications in drug development

    Article • Chemico-Biological Interactions, May 2007, Elsevier

    Albert Li

  24. Drug–Drug Interaction – Enzyme Induction

    Article • January 2006, Springer Science + Business Media

    Albert Li

  25. Preface

    Article • Chemico-Biological Interactions, November 2004, Elsevier

    Albert Li

  26. A comprehensive approach for drug safety assessment

    Article • Chemico-Biological Interactions, November 2004, Elsevier

    Albert Li

  27. An integrated, multidisciplinary approach for drug safety assessment

    Article • Drug Discovery Today, August 2004, Elsevier

    Albert Li

  28. In Vitro Approaches to Evaluate ADMET Drug Properties

    Article • Current Topics in Medicinal Chemistry, March 2004, Bentham Science Publishers

    Albert Li

  29. In vitro experimental models for the blood–brain barrier

    Article • Drug Discovery Today, March 2004, Elsevier

    Albert Li

  30. Advancing technologies for accelerated drug development

    Article • Drug Discovery Today, March 2003, Elsevier

    Albert Li

  31. Prediction of idiosyncratic drug toxicity

    Article • Chemico-Biological Interactions, November 2002, Elsevier

    Albert Li

  32. ADME-Tox Screening in Drug Discovery

    Article • March 2002, Taylor & Francis

    Albert Li

  33. Foreword

    Article • Chemico-Biological Interactions, May 2001, Elsevier

    Albert Li

  34. Screening for human ADME/Tox drug properties in drug discovery

    Article • Drug Discovery Today, April 2001, Elsevier

    Albert Li

  35. Human hepatocytes as an experimental system for the evaluation of xenobiotics

    Article • January 2000, Springer Science + Business Media

    Albert Li

  36. Overview: hepatocytes and cryopreservation—a personal historical perspective

    Article • Chemico-Biological Interactions, June 1999, Elsevier

    Albert Li

  37. Preface

    Article • January 1997, Elsevier

    Albert Li

  38. Overview: Pharmacokinetic Drug-Drug Interactions

    Article • January 1997, Elsevier

    Albert Li

  39. Human-Basedin vitro Experimental Systems for the Evaluation of Human Drug Safety

    Article • Wiley

    Albert Li

  40. In Vitro Evaluation of Metabolic Drug–Drug Interactions: Concepts and Practice

    Article • Wiley

    Albert Li

  41. Evaluation of Inhibitors of Drug Metabolism in Human Hepatocytes

    Article • Wiley

    Albert Li