All Stories

  1. Aging Biomarker SMP30 into a New Phase of Vitamin C and Aging Research

    Article • January 2022, Springer Science + Business Media

    Dr Akihito Ishigami

  2. Age-associated changes in the transcriptomes of non-cultured adipose-derived stem cells from young and old mice assessed via single-cell transcriptome analysis

    Article • PLOS One, November 2020, PLOS

    Dr Akihito Ishigami

  3. Role of Ascorbic Acid in Skeletal Muscle Regeneration

    Article • The FASEB Journal, April 2020, Wiley

    Dr Akihito Ishigami

  4. Peptidyl arginine deiminase inhibition suppresses arthritis via decreased protein citrullination in joints and serum with the downregulation of interlukin-6

    Article • Modern Rheumatology, October 2018, Taylor & Francis

    Dr Akihito Ishigami

  5. Anti-aging effects of coffee

    Article • Aging, August 2017, Impact Journals, LLC

    Dr Akihito Ishigami

  6. Coffee consumption in aged mice increases energy production and decreases hepatic mTOR levels

    Article • Nutrition, June 2017, Elsevier

    Dr Akihito Ishigami

  7. Update on Deimination in Alzheimer’s Disease

    Article • January 2017, Springer Science + Business Media

    Dr Akihito Ishigami

  8. Induction of peptidylarginine deiminase 2 and 3 by dibutyryl cAMP via cAMP-PKA signaling in human astrocytoma U-251MG cells

    Article • Journal of Neuroscience Research, October 2016, Wiley

    Dr Akihito Ishigami

  9. Involvement of senescence marker protein-30 in glucose metabolism disorder and non-alcoholic fatty liver disease

    Article • Geriatrics and Gerontology International, March 2016, Wiley

    Dr Akihito Ishigami

  10. Antioxidant nutrients in plasma of Japanese patients with chronic obstructive pulmonary disease, asthma-COPD overlap syndrome and bronchial asthma

    Article • The Clinical Respiratory Journal, January 2016, Wiley

    Dr Akihito Ishigami

  11. Mass spectrometric identification of citrullination sites and immunohistochemical detection of citrullinated glial fibrillary acidic protein in Alzheimer's disease brains

    Article • Journal of Neuroscience Research, July 2015, Wiley

    Dr Akihito Ishigami

  12. Age-associated decrease of senescence marker protein-30/gluconolactonase in individual mouse liver cells: Immunohistochemistry and immunofluorescence

    Article • Geriatrics and Gerontology International, October 2014, Wiley

    Dr Akihito Ishigami

  13. Potato Chip Intake Increases Ascorbic Acid Levels and Decreases Reactive Oxygen Species in SMP30/GNL Knockout Mouse Tissues

    Article • Journal of Agricultural and Food Chemistry, September 2014, American Chemical Society (ACS)

    Dr Akihito Ishigami

  14. Senescence marker protein‐30/gluconolactonase deficiency exacerbates diabetic nephropathy through tubular injury in a mouse model of type 1 diabetes

    Article • Journal of Diabetes Investigation, July 2014, Wiley

    Dr Akihito Ishigami

  15. Ascorbic acid deficiency affects genes for oxidation–reduction and lipid metabolism in livers from SMP30/GNL knockout mice

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, July 2014, Elsevier

    Dr Akihito Ishigami

  16. P43 Ascorbic acid deficiency augments hyperalgesia induced by hydrogen sulfide in mice

    Article • Nitric Oxide, May 2014, Elsevier

    Dr Akihito Ishigami

  17. Vitamin C and Physical Performance in the Elderly

    Article • January 2014, Elsevier

    Dr Akihito Ishigami

  18. Senescence marker protein‐30/superoxide dismutase 1 double knockout mice exhibit increased oxidative stress and hepatic steatosis

    Article • FEBS Open Bio, January 2014, Wiley

    Dr Akihito Ishigami

  19. Senescence Marker Protein 30 Has a Cardio-Protective Role in Doxorubicin-Induced Cardiac Dysfunction

    Article • PLOS One, December 2013, PLOS

    Dr Akihito Ishigami

  20. Smad3 Deficiency Ameliorates Hepatic Fibrogenesis through the Expression of Senescence Marker Protein-30, an Antioxidant-Related Protein

    Article • International Journal of Molecular Sciences, December 2013, MDPI AG

    Dr Akihito Ishigami

  21. Ascorbic acid prevents protein oxidation in livers of senescence marker protein-30/gluconolactonase knockout mice

    Article • Geriatrics and Gerontology International, October 2013, Wiley

    Dr Akihito Ishigami

  22. Effects of Vitamin C on Cytotherapy-Mediated Muscle Regeneration

    Article • Cell Transplantation, October 2013, SAGE Publications

    Dr Akihito Ishigami

  23. Coronary Artery Spasm Related to Thiol Oxidation and Senescence Marker Protein-30 in Aging

    Article • Antioxidants & Redox Signaling, October 2013, Mary Ann Liebert Inc

    Dr Akihito Ishigami

  24. Deimination in Alzheimer’s Disease

    Article • September 2013, Springer Science + Business Media

    Dr Akihito Ishigami

  25. Deimination in Prion Diseases

    Article • September 2013, Springer Science + Business Media

    Dr Akihito Ishigami

  26. Vitamin C Prevents Cigarette Smoke-Induced Pulmonary Emphysema in Mice and Provides Pulmonary Restoration

    Article • American Journal of Respiratory Cell and Molecular Biology, September 2013, American Thoracic Society

    Dr Akihito Ishigami

  27. Senescence marker protein 30 inhibits angiotensin II-induced cardiac hypertrophy and diastolic dysfunction

    Article • Biochemical and Biophysical Research Communications, September 2013, Elsevier

    Dr Akihito Ishigami

  28. Two novel sandwich ELISAs identify PAD4 levels and PAD4 autoantibodies in patients with rheumatoid arthritis

    Article • Modern Rheumatology, July 2013, Oxford University Press (OUP)

    Dr Akihito Ishigami

  29. Leprdb/db Mice with Senescence Marker Protein-30 Knockout (Leprdb/dbSmp30Y/−) Exhibit Increases in Small Dense-LDL and Severe Fatty Liver Despite Being Fed a Standard Diet

    Article • PLOS One, June 2013, PLOS

    Dr Akihito Ishigami

  30. Senescence Marker Protein-30 (SMP30) Deficiency Impairs Myocardium-Induced Dilation of Coronary Arterioles Associated with Reactive Oxygen Species

    Article • International Journal of Molecular Sciences, April 2013, MDPI AG

    Dr Akihito Ishigami

  31. Exome sequencing of senescence-accelerated mice (SAM) reveals deleterious mutations in degenerative disease-causing genes

    Article • BMC Genomics, April 2013, Springer Science + Business Media

    Dr Akihito Ishigami

  32. Senescence marker protein 30 deficiency increases Parkinson's pathology by impairing astrocyte activation

    Article • Neurobiology of Aging, April 2013, Elsevier

    Dr Akihito Ishigami

  33. Effect of ascorbic acid deficiency on catecholamine synthesis in adrenal glands of SMP30/GNL knockout mice

    Article • Zeitschrift für Ernährungswissenschaft, March 2013, Springer Science + Business Media

    Dr Akihito Ishigami

  34. Age-related oxidant stress with senescence marker protein-30 deficiency plays a pivotal role in coronary artery spasm

    Article • Coronary Artery Disease, March 2013, Wolters Kluwer Health

    Dr Akihito Ishigami

  35. Insufficient ascorbic acid intake during gestation induces abnormal cardiac dilation in fetal and neonatal SMP30/GNL knockout mice

    Article • Pediatric Research, February 2013, Springer Science + Business Media

    Dr Akihito Ishigami

  36. Structural Basis of the γ-Lactone-Ring Formation in Ascorbic Acid Biosynthesis by the Senescence Marker Protein-30/Gluconolactonase

    Article • PLOS One, January 2013, PLOS

    Dr Akihito Ishigami

  37. Senescence Marker Protein-30/Gluconolactonase Expression in the Mouse Ovary during Gestation

    Article • Biological and Pharmaceutical Bulletin, January 2013, Pharmaceutical Society of Japan

    Dr Akihito Ishigami

  38. Peptidylarginine deiminase and protein citrullination in prion diseases

    Article • Prion, January 2013, Taylor & Francis

    Dr Akihito Ishigami

  39. Ascorbic acid enhances the expression of type 1 and type 4 collagen and SVCT2 in cultured human skin fibroblasts

    Article • Biochemical and Biophysical Research Communications, January 2013, Elsevier

    Dr Akihito Ishigami

  40. Effects of Ascorbic Acid Deficiency on Protein and Lipid Oxidation in Livers from SMP30/GNL Knockout Mice

    Article • Journal of Nutritional Science and Vitaminology, January 2013, Center for Academic Publications Japan

    Dr Akihito Ishigami

  41. The Effect of Vitamin C C-onsumption on the Oxidative Stress Regulation System in SMP30/GNL Knockout Mice

    Article • Japanese Journal of Complementary and Alternative Medicine, January 2013, Japanese Society for Complementary & Alternative Medicine

    Dr Akihito Ishigami

  42. ChemInform Abstract: Synthesis and Evaluation of 4‐Aryl‐2(1H)‐quinolinones as Potent Amyloid β Fibrillogenesis Inhibitors.

    Article • ChemInform, November 2012, Wiley

    Dr Akihito Ishigami

  43. Age‐related changes of dopamine, noradrenaline and adrenaline in adrenal glands of mice

    Article • Geriatrics and Gerontology International, August 2012, Wiley

    Dr Akihito Ishigami

  44. Ascorbic Acid Deficiency Leads to Epidermal Atrophy and UVB-Induced Skin Pigmentation in SMP30/GNL Knockout Hairless Mice

    Article • Journal of Investigative Dermatology, August 2012, Elsevier

    Dr Akihito Ishigami

  45. Peptidylarginine deiminase modulates the physiological roles of enolase via citrullination: links between altered multifunction of enolase and neurodegenerative diseases

    Article • Biochemical Journal, July 2012, Portland Press Ltd.

    Dr Akihito Ishigami

  46. Synthesis and Evaluation of 4-Aryl-2(1H)-quinolinones as Potent Amyloid β Fibrillogenesis Inhibitors

    Article • Heterocycles, January 2012, Japan Institute of Heterocyclic Chemistry

    Dr Akihito Ishigami

  47. Ascorbic Acid Levels in Various Tissues, Plasma and Urine of Mice during Aging

    Article • Journal of Nutritional Science and Vitaminology, January 2012, Center for Academic Publications Japan

    Dr Akihito Ishigami

  48. Uric Acid Levels in Tissues and Plasma of Mice during Aging

    Article • Biological and Pharmaceutical Bulletin, January 2012, Pharmaceutical Society of Japan

    Dr Akihito Ishigami

  49. Development of a New Distyrylbenzene-Derivative Amyloid-^|^#946;-aggregation and Fibril Formation Inhibitor

    Article • Chemical and Pharmaceutical Bulletin, January 2012, Pharmaceutical Society of Japan

    Dr Akihito Ishigami

  50. Effect of vitamin C depletion on UVR-B induced cataract in SMP30/GNL knockout mice

    Article • Experimental Eye Research, January 2012, Elsevier

    Dr Akihito Ishigami

  51. Pancreatic insulin release in vitamin C-deficient senescence marker protein-30/gluconolactonase knockout mice

    Article • Journal of Clinical Biochemistry and Nutrition, January 2012, The Society for Free Radical Research Japan

    Dr Akihito Ishigami

  52. 17β-Estradiol attenuates saturated fatty acid diet-induced liver injury in ovariectomized mice by up-regulating hepatic senescence marker protein-30

    Article • Biochemical and Biophysical Research Communications, November 2011, Elsevier

    Dr Akihito Ishigami

  53. Bioavailability of vitamin C from mashed potatoes and potato chips after oral administration in healthy Japanese men

    Article • British Journal Of Nutrition, September 2011, Cambridge University Press

    Dr Akihito Ishigami

  54. Time course of vitamin C distribution and absorption after oral administration in SMP30/GNL knockout mice

    Article • Nutrition, April 2011, Elsevier

    Dr Akihito Ishigami

  55. Subcellular Localization of Peptidylarginine Deiminase 2 and Citrullinated Proteins in Brains of Scrapie-Infected Mice: Nuclear Localization of PAD2 and Membrane Fraction-Enriched Citrullinated Proteins

    Article • Journal of Neuropathology & Experimental Neurology, February 2011, Oxford University Press (OUP)

    Dr Akihito Ishigami

  56. Absorption and Excretion of Ascorbic Acid Alone and in Acerola (Malpighia emarginata) Juice: Comparison in Healthy Japanese Subjects

    Article • Biological and Pharmaceutical Bulletin, January 2011, Pharmaceutical Society of Japan

    Dr Akihito Ishigami

  57. Vitamin C deficiency increases the binucleation of hepatocytes in SMP30 knock‐out mice

    Article • Journal of Gastroenterology and Hepatology, October 2010, Wiley

    Dr Akihito Ishigami

  58. Pathophysiological significance of senescence marker protein‐30

    Article • Geriatrics and Gerontology International, June 2010, Wiley

    Dr Akihito Ishigami

  59. Importance of research on peptidylarginine deiminase and citrullinated proteins in age‐related disease

    Article • Geriatrics and Gerontology International, June 2010, Wiley

    Dr Akihito Ishigami

  60. ChemInform Abstract: anti‐Aging Research Using SMP30/GNL Knockout Mice

    Article • ChemInform, May 2010, Wiley

    Dr Akihito Ishigami

  61. Corrigendum to “Effects of vitamin C deficiency on the skin of the senescence marker protein-30 (SMP30) knockout mouse” [Biochem. Biophys. Res. Commun. 385 (2009) 478–483]

    Article • Biochemical and Biophysical Research Communications, May 2010, Elsevier

    Dr Akihito Ishigami

  62. Vitamin C Deficiency Attenuates Liver Fibrosis by Way of Up-Regulated Peroxisome Proliferator-Activated Receptor-Gamma Expression in Senescence Marker Protein 30 Knockout Mice

    Article • Hepatology, May 2010, Wolters Kluwer Health

    Dr Akihito Ishigami

  63. Ascorbic acid depletion enhances expression of the sodium-dependent vitamin C transporters, SVCT1 and SVCT2, and uptake of ascorbic acid in livers of SMP30/GNL knockout mice

    Article • Archives of Biochemistry and Biophysics, April 2010, Elsevier

    Dr Akihito Ishigami

  64. Senescence Marker Protein-30/Gluconolactonase Deletion Worsens Glucose Tolerance through Impairment of Acute Insulin Secretion

    Article • Endocrinology, February 2010, Endocrine Society

    Dr Akihito Ishigami

  65. Anti-aging Research Using SMP30/GNL Knockout Mice

    Article • YAKUGAKU ZASSHI, January 2010, Pharmaceutical Society of Japan

    Dr Akihito Ishigami

  66. Advanced Approaches to Anti-aging —Use of Aging Model Animals—

    Article • YAKUGAKU ZASSHI, January 2010, Pharmaceutical Society of Japan

    Dr Akihito Ishigami

  67. Accumulation of amyloid β-like substances in aging Aplysia kurodai CNS

    Article • Neuroscience Research, January 2010, Elsevier

    Dr Akihito Ishigami

  68. Determination of Dehydroascorbic Acid in Mouse Tissues and Plasma by Using Tris(2-carboxyethyl)phosphine Hydrochloride as Reductant in Metaphosphoric Acid/Ethylenediaminetetraacetic Acid Solution

    Article • Biological and Pharmaceutical Bulletin, January 2010, Pharmaceutical Society of Japan

    Dr Akihito Ishigami

  69. Involvement of peptidylarginine deiminase-mediated post-translational citrullination in pathogenesis of sporadic Creutzfeldt-Jakob disease

    Article • Acta Neuropathologica, December 2009, Springer Science + Business Media

    Dr Akihito Ishigami

  70. Effect of vitamin C depletion on age-related hearing loss in SMP30/GNL knockout mice

    Article • Biochemical and Biophysical Research Communications, December 2009, Elsevier

    Dr Akihito Ishigami

  71. Hepatic senescence marker protein-30 is involved in the progression of nonalcoholic fatty liver disease

    Article • Journal of Gastroenterology, November 2009, Springer Science + Business Media

    Dr Akihito Ishigami

  72. Developmental and age‐related changes of peptidylarginine deiminase 2 in the mouse brain

    Article • Journal of Neuroscience Research, October 2009, Wiley

    Dr Akihito Ishigami

  73. Effects of vitamin C deficiency on the skin of the senescence marker protein-30 (SMP30) knockout mouse

    Article • Biochemical and Biophysical Research Communications, July 2009, Elsevier

    Dr Akihito Ishigami

  74. Senescence marker protein 30 is up‐regulated in kainate‐induced hippocampal damage through ERK‐mediated astrocytosis

    Article • Journal of Neuroscience Research, May 2009, Wiley

    Dr Akihito Ishigami

  75. Implication of p53-dependent cellular senescence related gene, TARSH in tumor suppression

    Article • Biochemical and Biophysical Research Communications, March 2009, Elsevier

    Dr Akihito Ishigami

  76. Over-expression of Senescence Marker Protein-30 Decreases Reactive Oxygen Species in Human Hepatic Carcinoma Hep G2 Cells

    Article • Biological and Pharmaceutical Bulletin, January 2009, Pharmaceutical Society of Japan

    Dr Akihito Ishigami

  77. Elevated levels of 4-hydroxynonenal-histidine Michael adduct in the hippocampi of patients with Alzheimer's disease

    Article • Biomedical Research, January 2009, Biomedical Research Press

    Dr Akihito Ishigami

  78. Vitamin C depletion increases superoxide generation in brains of SMP30/GNL knockout mice

    Article • Biochemical and Biophysical Research Communications, December 2008, Elsevier

    Dr Akihito Ishigami

  79. Accumulation of Citrullinated Proteins by Up-Regulated Peptidylarginine Deiminase 2 in Brains of Scrapie-Infected Mice

    Article • American Journal Of Pathology, October 2008, Elsevier

    Dr Akihito Ishigami

  80. Hydrogen-rich pure water prevents superoxide formation in brain slices of vitamin C-depleted SMP30/GNL knockout mice

    Article • Biochemical and Biophysical Research Communications, October 2008, Elsevier

    Dr Akihito Ishigami

  81. Age-related difference of site-specific histone modifications in rat liver

    Article • Biogerontology, September 2008, Springer Science + Business Media

    Dr Akihito Ishigami

  82. Myasthenia Gravis Experimentally Induced with Muscle‐specific Kinase

    Article • Annals of the New York Academy of Sciences, June 2008, Wiley

    Dr Akihito Ishigami

  83. Germ Cell-Specific Expression and Biochemical Characterization of Mouse PAD6.

    Article • Biology of Reproduction, May 2008, Oxford University Press (OUP)

    Dr Akihito Ishigami

  84. Hepatoprotective effect of Arazyme on CCl4-induced acute hepatic injury in SMP30 knock-out mice

    Article • Toxicology, April 2008, Elsevier

    Dr Akihito Ishigami

  85. Vitamin C Is Not Essential for Carnitine Biosynthesis in Vivo: Verification in Vitamin C-Depleted Senescence Marker Protein-30/Gluconolactonase Knockout Mice

    Article • Biological and Pharmaceutical Bulletin, January 2008, Pharmaceutical Society of Japan

    Dr Akihito Ishigami

  86. Significance of SMP30 in gerontology

    Article • Geriatrics and Gerontology International, December 2007, Wiley

    Dr Akihito Ishigami

  87. Microglial expression of peptidylarginine deiminase 2 in the prenatal rat brain

    Article • Cellular & Molecular Biology Letters, January 2007, De Gruyter

    Dr Akihito Ishigami

  88. Senescence Marker Protein-30 Protects Mice Lungs from Oxidative Stress, Aging, and Smoking

    Article • American Review of Respiratory Disease, September 2006, American Thoracic Society

    Dr Akihito Ishigami

  89. P4–122: Abnormal accumulation of citrullinated proteins in scrapie–infected mouse brain

    Article • Alzheimer s & Dementia, July 2006, Wiley

    Dr Akihito Ishigami

  90. SMP30 deficiency causes increased oxidative stress in brain

    Article • Mechanisms of Ageing and Development, May 2006, Elsevier

    Dr Akihito Ishigami

  91. The Redox-Sensitive DNA Binding Sites Responsible for Age-Related Downregulation of SMP30 by ERK Pathway and Reversal by Calorie Restriction

    Article • Antioxidants & Redox Signaling, March 2006, Mary Ann Liebert Inc

    Dr Akihito Ishigami

  92. A Selective NF.KAPPA.B Inhibitor, DHMEQ, Reduced Atherosclerosis in ApoE-deficient mice

    Article • Journal of Atherosclerosis and Thrombosis, January 2006, Japan Atherosclerosis Society

    Dr Akihito Ishigami

  93. Citrullination preferentially proceeds in glomerular Bowman's capsule and increases in obstructive nephropathy

    Article • Kidney International, July 2005, Elsevier

    Dr Akihito Ishigami

  94. Senescence marker protein-30 (SMP30) induces formation of microvilli and bile canaliculi in Hep G2 cells

    Article • Cell and Tissue Research, February 2005, Springer Science + Business Media

    Dr Akihito Ishigami

  95. Abnormal accumulation of citrullinated proteins catalyzed by peptidylarginine deiminase in hippocampal extracts from patients with Alzheimer's disease

    Article • Journal of Neuroscience Research, January 2005, Wiley

    Dr Akihito Ishigami

  96. Modulation of gene expression of SMP-30 by LPS and calorie restriction during aging process

    Article • Experimental Gerontology, August 2004, Elsevier

    Dr Akihito Ishigami

  97. Senescence marker protein-30 regulates Akt activity and contributes to cell survival in Hep G2 cells

    Article • Biochemical and Biophysical Research Communications, August 2004, Elsevier

    Dr Akihito Ishigami

  98. Senescence marker protein‐30 is a unique enzyme that hydrolyzes diisopropyl phosphorofluoridate in the liver

    Article • FEBS Letters, July 2004, Wiley

    Dr Akihito Ishigami

  99. Senescence Marker Protein‐30 as a Novel Antiaging Molecule

    Article • Annals of the New York Academy of Sciences, June 2004, Wiley

    Dr Akihito Ishigami

  100. Senescence Marker Protein‐30 Knockout Mouse as an Aging Model

    Article • Annals of the New York Academy of Sciences, June 2004, Wiley

    Dr Akihito Ishigami

  101. SMP30 deficiency in mice causes an accumulation of neutral lipids and phospholipids in the liver and shortens the life span

    Article • Biochemical and Biophysical Research Communications, March 2004, Elsevier

    Dr Akihito Ishigami

  102. Senescence marker protein‐30 knockout mouse as a novel murine model of senile lung

    Article • Pathology International, February 2004, Wiley

    Dr Akihito Ishigami

  103. cDNA cloning, gene organization and expression analysis of human peptidylarginine deiminase type I

    Article • Biochemical Journal, February 2003, Portland Press Ltd.

    Dr Akihito Ishigami

  104. Nuclear Localization of Senescence Marker Protein-30, SMP30, in Cultured Mouse Hepatocytes and Its Similarity to RNA Polymerase

    Article • Bioscience Biotechnology and Biochemistry, January 2003, Taylor & Francis

    Dr Akihito Ishigami

  105. Human peptidylarginine deiminase type II: molecular cloning, gene organization, and expression in human skin

    Article • Archives of Biochemistry and Biophysics, November 2002, Elsevier

    Dr Akihito Ishigami

  106. Senescence Marker Protein-30 Knockout Mouse Liver Is Highly Susceptible to Tumor Necrosis Factor-α- and Fas-Mediated Apoptosis

    Article • American Journal Of Pathology, October 2002, Elsevier

    Dr Akihito Ishigami

  107. Increased and type II-specific expression of peptidylarginine deiminase in activated microglia but not hyperplastic astrocytes following kainic acid-evoked neurodegeneration in the rat brain

    Article • Neuroscience Letters, June 2002, Elsevier

    Dr Akihito Ishigami

  108. Protein Deimination and Peptidylarginine Deiminase Expression during Cornification of Rat Epidermal Keratinocytes

    Article • Biomedical Research, January 2002, Biomedical Research Press

    Dr Akihito Ishigami

  109. Regulatory effects of senescence marker protein 30 on the proliferation of hepatocytes

    Article • Pathology International, July 2001, Wiley

    Dr Akihito Ishigami, Professor amedeo columbano

  110. Protein deimination in the rat brain after kainate administration: citrulline-containing proteins as a novel marker of neurodegeneration

    Article • Neuroscience Letters, February 2001, Elsevier

    Dr Akihito Ishigami

  111. Molecular cloning of two novel types of peptidylarginine deiminase cDNAs from retinoic acid‐treated culture of a newborn rat keratinocyte cell line

    Article • FEBS Letters, August 1998, Wiley

    Dr Akihito Ishigami

  112. All-TransRetinoic Acid Increases Peptidylarginine Deiminases in a Newborn Rat Keratinocyte Cell Line

    Article • Biochemical and Biophysical Research Communications, June 1996, Elsevier

    Dr Akihito Ishigami

  113. Detection of Deiminated Proteins in Rat Skin: Probing with a Monospecific Antibody After Modification of Citrulline Residues

    Article • Journal of Investigative Dermatology, August 1995, Elsevier

    Dr Akihito Ishigami

  114. Age‐related changes in DNA synthesis stimulated by epinephrine and isoproterenol in primary cultured rat hepatocytes

    Article • Journal of Cellular Physiology, February 1994, Wiley

    Dr Akihito Ishigami

  115. Effect of dietary restriction on the degradation of proteins in senescent mouse liver parenchymal cells in culture

    Article • Archives of Biochemistry and Biophysics, December 1990, Elsevier

    Dr Akihito Ishigami

  116. Age-related change in the degradation rate of ovalbumin microinjected into mouse liver parenchymal cells

    Article • Archives of Biochemistry and Biophysics, February 1990, Elsevier

    Dr Akihito Ishigami

  117. Inactivation kinetics of horseradish peroxidase microinjected into hepatocytes from mice of various ages

    Article • Mechanisms of Ageing and Development, January 1988, Elsevier

    Dr Akihito Ishigami