All Stories

  1. Exploring 1,3,4-Oxadiazole derivatives of 3,4-Dihydroxyphenylacetic acid as potent α-glucosidase inhibitors: Synthesis, structure-activity relationship, molecular docking, and DFT studies

    Article • Journal of Molecular Structure, April 2025, Elsevier

    Aftab Alam

  2. Exploring the Versatility of Azine Derivatives: A Comprehensive Review on Synthesis and Biological Applications

    Article • Mini-Reviews in Medicinal Chemistry, April 2025, Bentham Science Publishers

    Aftab Alam

  3. Ketorolac-based ester derivatives as promising hits for malignant glioma: Synthesis, brain cancer activity, molecular docking, dynamic simulation and DFT investigation

    Article • Journal of Molecular Structure, April 2025, Elsevier

    Aftab Alam

  4. Benzothiazole Derived Ether Hybrids as Potent Anti‐Thymidine Phosphorylase Agents: Synthesis, In Vitro, and Computational Investigations

    Article • Chemistry & Biodiversity, February 2025, Wiley

    Aftab Alam

  5. Experimental and computational profiling of novel bis-Schiff base derivatives bearing α-naphthalene moiety as potential tyrosinase inhibitors

    Article • Journal of Molecular Structure, February 2025, Elsevier

    Aftab Alam

  6. Exploring the anti-diabetic activity of benzimidazole containing Schiff base derivatives: In vitro α-amylase, α-glucosidase inhibitions and in silico studies

    Article • Journal of Molecular Structure, February 2025, Elsevier

    Aftab Alam

  7. Flurbiprofen clubbed schiff's base derivatives as potent anticancer agents: In Vitro and In Silico approach towards breast cancer

    Article • Journal of Molecular Structure, February 2025, Elsevier

    Aftab Alam

  8. Synthesis of novel thiazole derivatives containing 3-methylthiophene carbaldehyde as potent anti α-glucosidase agents: In vitro evaluation, molecular docking, dynamics, MM-GBSA, and DFT studies

    Article • Journal of Molecular Structure, February 2025, Elsevier

    Aftab Alam

  9. Synthesis, anticancer, α-glucosidase inhibition, molecular docking and dynamics studies of hydrazone-Schiff bases bearing polyhydroquinoline scaffold: In vitro and in silico approaches

    Article • Journal of Molecular Structure, February 2025, Elsevier

    Aftab Alam

  10. Copper(II) complexes of 2-hydroxy-1-naphthaldehyde Schiff bases: synthesis, in vitro activity and computational studies

    Article • Future Medicinal Chemistry, January 2025, Taylor & Francis

    Aftab Alam

  11. Synthesis, characterization, enzyme inhibition and molecular docking studies of benzothiazole derivatives bearing alkyl phenyl ether fragments

    Article • Journal of Molecular Structure, January 2025, Elsevier

    Aftab Alam

  12. Synthesis and Multi‐Target Inhibition of Bis‐Schiff Bases of Barbituric Acid: in Vitro α‐glucosidase, α‐amylase Inhibitory Activities With Docking and DFT Studies

    Article • ChemistrySelect, December 2024, Wiley

    Aftab Alam

  13. Synthesis of Some Novel 4-bromobenzoic Acid Clubbed Hydrazone Schiff Base Derivatives as Potent α-amylase Inhibitors: In vitro and In silico Studies

    Article • Letters in Drug Design & Discovery, December 2024, Bentham Science Publishers

    Aftab Alam

  14. Synthesis, Urease Inhibitory Activity, Molecular Docking, Dynamics, MMGBSA and DFT Studies of Hydrazone‐Schiff Bases Bearing Benzimidazole Scaffold

    Article • Chemistry & Biodiversity, November 2024, Wiley

    Aftab Alam

  15. Investigating the Tyrosinase Inhibitory Activity of 4‐Bromobenzoic Acid Hydrazone‐Schiff Bases: In Vitro, Molecular Structure and Docking Studies

    Article • ChemistrySelect, November 2024, Wiley

    Aftab Alam

  16. Synthesis and Molecular Docking Study of Hydrazone Schiff Bases of α‐Naphthalene‐Containing Alkyl Phenyl Ether Fragment as Potent α‐Amylase and α‐Glucosidase Inhibitors

    Article • ChemistrySelect, November 2024, Wiley

    Aftab Alam

  17. Synthesis of novel (S)-flurbiprofen-based esters for cancer treatment by targeting thymidine phosphorylase via Biomolecular Approaches

    Article • Journal of Molecular Structure, November 2024, Elsevier

    Aftab Alam

  18. Exploring bis-Schiff Bases with Thiobarbiturate Scaffold: In Vitro Urease Inhibition, Antioxidant Properties, and In Silico Studies

    Article • Russian Journal of Bioorganic Chemistry, October 2024, Pleiades Publishing Ltd

    Aftab Alam

  19. Novel benzimidazole-based azine derivatives as potent urease inhibitors: synthesis, in vitro and in silico approach

    Article • Future Medicinal Chemistry, September 2024, Taylor & Francis

    Aftab Alam

  20. Synthesis of Novel Benzimidazole Analogs for Neurodegenerative Diseases by Targeting Prolyl Oligopeptidase

    Article • ChemistrySelect, September 2024, Wiley

    Aftab Alam

  21. Discovering the anti-diabetic potential of thiosemicarbazone derivatives: In vitro α-glucosidase, α-amylase inhibitory activities with molecular docking and DFT investigations

    Article • Journal of Molecular Structure, September 2024, Elsevier

    Aftab Alam

  22. Synthesis of novel 2-mercapto-1,3,4-oxadiazole derivatives as potent urease inhibitors: In vitro and in silico investigations

    Article • Journal of Molecular Structure, September 2024, Elsevier

    Aftab Alam

  23. Thiosemicarbazone derivatives as potent antidiabetic agents: Synthesis, in vitro, molecular docking and DFT investigations

    Article • Journal of Molecular Structure, September 2024, Elsevier

    Aftab Alam

  24. Exploring the synthesis, molecular structure and biological activities of novel Bis-Schiff base derivatives: A combined theoretical and experimental approach

    Article • Journal of Molecular Structure, June 2024, Elsevier

    Aftab Alam

  25. Synthesis of 2,4-dihydroxyacetophenone derivatives as potent PDE-1 and -3 inhibitors: in vitro and in silico insights

    Article • Future Medicinal Chemistry, May 2024, Taylor & Francis

    Aftab Alam

  26. Multifaceted bioactivity of thiosemicarbazide derivatives: Synthesis, characterization, and DFT investigations on inhibition of α-amylase, hydroxyl radical scavenging, and iron chelating activities with molecular docking insights

    Article • Journal of Molecular Structure, May 2024, Elsevier

    Aftab Alam

  27. Novel hydrazone schiff’s base derivatives of polyhydroquinoline: synthesis, in vitro prolyl oligopeptidase inhibitory activity and their Molecular docking study

    Article • Journal of Biomolecular Structure and Dynamics, February 2024, Taylor & Francis

    Aftab Alam

  28. Investigating Novel Thiophene Carbaldehyde Based Thiazole Derivatives as Potential Hits for Diabetic Management: Synthesis, In Vitro and In Silico Approach

    Article • ChemistrySelect, February 2024, Wiley

    Aftab Alam

  29. Synthesis, molecular docking and DFT analysis of novel bis-Schiff base derivatives with thiobarbituric acid for α-glucosidase inhibition assessment

    Article • Scientific Reports, February 2024, Springer Science + Business Media

    Aftab Alam

  30. Synthesis of new bis(dimethylamino)benzophenone hydrazone for diabetic management: In-vitro and in-silico approach

    Article • Heliyon, January 2024, Elsevier

    Aftab Alam

  31. Biooriented Synthesis of Ibuprofen-Clubbed Novel Bis-Schiff Base Derivatives as Potential Hits for Malignant Glioma: In Vitro Anticancer Activity and In Silico Approach

    Article • ACS Omega, December 2023, American Chemical Society (ACS)

    Aftab Alam

  32. Novel Benzimidazole Derivatives as Effective Inhibitors of Prolyl Oligopeptidase: Synthesis, in Vitro and in Silico Analysis

    Article • Future Medicinal Chemistry, December 2023, Taylor & Francis

    Aftab Alam

  33. Discovery of (S)-flurbiprofen-based novel azine derivatives as prostaglandin endoperoxide synthase-II inhibitors: Synthesis, in-vivo analgesic, anti-inflammatory activities, and their molecular docking

    Article • Bioorganic Chemistry, December 2023, Elsevier

    Aftab Alam

  34. Exploring the synthesis, structure, spectroscopy and biological activities of novel 4-benzylidene-1-(2-(2,4-dichloro phenyl)acetyl) thiosemicarbazide derivatives: An integrated experimental and theoretical investigation

    Article • Saudi Pharmaceutical Journal, December 2023, Springer Science + Business Media

    Aftab Alam

  35. Synthetic Transformation of 4-fluorobenzoic Acid to 4-fluorobenzohydrazide Schiff Bases and 1,3,4-Oxadiazole Analogs having DPPH Radical Scavenging Potential

    Article • Letters in Drug Design & Discovery, December 2023, Elsevier

    Aftab Alam

  36. Polyhydroquinoline Derivatives for Diabetic Management: Synthesis, in Vitro and in Silico Approaches

    Article • Future Medicinal Chemistry, November 2023, Taylor & Francis

    Aftab Alam

  37. Synthesis, Antibacterial Activities and Theoretical Study of Polyhydroquinoline Derivatives

    Article • ChemistrySelect, November 2023, Wiley

    Aftab Alam

  38. Antioxidant Activity, Molecular Docking and Quantum Studies of New Bis‐Schiff Bases Based on Benzyl Phenyl Ketone Moiety

    Article • ChemistrySelect, September 2023, Wiley

    Aftab Alam

  39. Flurbiprofen Derivatives as Potential DPPH and ABTS Radical Scavengers

    Article • Russian Journal of Organic Chemistry, September 2023, Pleiades Publishing Ltd

    Aftab Alam

  40. Synthesis, molecular structure and urease inhibitory activity of novel bis-Schiff bases of benzyl phenyl ketone: A combined theoretical and experimental approach

    Article • Saudi Pharmaceutical Journal, August 2023, Springer Science + Business Media

    Aftab Alam

  41. Novel polyhydroquinoline Schiff’s base derivatives: synthesis, characterization, in vitro α-glucosidase inhibitory, and molecular docking studies

    Article • Research on Chemical Intermediates, May 2023, Springer Science + Business Media

    Aftab Alam

  42. Bio-Oriented Synthesis of Novel Polyhydroquinoline Derivatives as α-Glucosidase Inhibitor for Management of Diabetes

    Article • ACS Omega, February 2023, American Chemical Society (ACS)

    Aftab Alam

  43. Synthesis and characterization of biologically active flurbiprofen amide derivatives as selective prostaglandin-endoperoxide synthase II inhibitors: In vivo anti-inflammatory activity and molecular docking

    Article • International Journal of Biological Macromolecules, February 2023, Elsevier

    Aftab Alam

  44. Para-Substituted Thiosemicarbazones as Cholinesterase Inhibitors: Synthesis, In Vitro Biological Evaluation, and In Silico Study

    Article • ACS Omega, January 2023, American Chemical Society (ACS)

    Aftab Alam

  45. Novel flurbiprofen clubbed oxadiazole derivatives as potential urease inhibitors and their molecular docking study

    Article • RSC Advances, January 2023, Royal Society of Chemistry

    Aftab Alam

  46. Synthetic Transformation of 2-{2-Fluoro[1,1′-biphenyl]-4-yl} Propanoic Acid into Hydrazide–Hydrazone Derivatives: In Vitro Urease Inhibition and In Silico Study

    Article • ACS Omega, November 2022, American Chemical Society (ACS)

    Aftab Alam

  47. Novel Polyhydroquinoline-Hydrazide-Linked Schiff’s Base Derivatives: Multistep Synthesis, Antimicrobial, and Calcium-Channel-Blocking Activities

    Article • Antibiotics, November 2022, MDPI AG

    Aftab Alam

  48. Novel Bis-Schiff’s base derivatives of 4-nitroacetophenone as potent α-glucosidase agents: Design, synthesis and in silico approach

    Article • Bioorganic Chemistry, November 2022, Elsevier

    Aftab Alam

  49. Design, Synthesis, Crystal Structure, In Vitro and In Silico Evaluation of New N′-Benzylidene-4-tert-butylbenzohydrazide Derivatives as Potent Urease Inhibitors

    Article • Molecules, October 2022, MDPI AG

    Aftab Alam

  50. A study on green synthesis, characterization of chromium oxide nanoparticles and their enzyme inhibitory potential

    Article • Frontiers in Pharmacology, October 2022, Frontiers

    Aftab Alam

  51. Bio-Oriented Synthesis of Novel (S)-Flurbiprofen Clubbed Hydrazone Schiff’s Bases for Diabetic Management: In Vitro and In Silico Studies

    Article • Pharmaceuticals, May 2022, MDPI AG

    Aftab Alam

  52. 4-Bromobenzohydrzide Derivatives as Potent α-amylase Enzyme Inhibitors; Synthesis, in Vitro and in Silico Studies

    Article • February 2022, Research Square

    Aftab Alam

  53. Chalcones: As potent α-amylase enzyme inhibitors; synthesis, in vitro, and in silico studies

    Article • Medicinal Chemistry, June 2020, Bentham Science Publishers

    Mr. Irfan Ali, Aftab Alam

  54. Flurbiprofen derivatives as novel α-amylase inhibitors: Biology-oriented drug synthesis (BIODS), in vitro, and in silico evaluation

    Article • Bioorganic Chemistry, December 2018, Elsevier

    Aftab Alam