All Stories

  1. Spatial Localization and Binding of the Probiotic Lactobacillus farciminis to the Rat Intestinal Mucosa: Influence of Chronic Stress

    Article • PLoS ONE, September 2015, PLOS

    Dr Afifa Ait-Belgnaoui

  2. Effect of commensals and probiotics on visceral sensitivity and pain in irritable bowel syndrome

    Article • Gut Microbes, May 2014, Taylor & Francis

    Dr Afifa Ait-Belgnaoui

  3. 249 Premature Gut and Neonatal Stress: High Intestinal Glucocorticoid Responsiveness in Early Life Shapes the Risk of Epithelial Barrier Defect in Response to Maternal Separation

    Article • Gastroenterology, May 2014, Elsevier

    Dr Afifa Ait-Belgnaoui

  4. Changes in Intestinal Glucocorticoid Sensitivity in Early Life Shape the Risk of Epithelial Barrier Defect in Maternal-Deprived Rats

    Article • PLoS ONE, February 2014, PLOS

    Dr Afifa Ait-Belgnaoui

  5. Probiotic gut effect prevents the chronic psychological stress‐induced brain activity abnormality in mice

    Article • Neurogastroenterology & Motility, December 2013, Wiley

    Dr Thomas A Tompkins, Dr Afifa Ait-Belgnaoui

  6. P075 Modulation du microbiote intestinale par un probiotique (Probio'Stick®) : impact sur l’activité cérébrale dans un modèle de stress chronique

    Article • Cahiers de Nutrition et de Diététique, December 2013, Elsevier

    Dr Afifa Ait-Belgnaoui, Dr Thomas A Tompkins

  7. P075 Modulation du microbiote intestinale par un probiotique (Probio'Stick®) : impact sur l’activité cérébrale dans un modèle de stress chronique

    Article • Nutrition Clinique et Métabolisme, December 2013, Elsevier

    Dr Afifa Ait-Belgnaoui, Dr Thomas A Tompkins

  8. Luminal Cysteine-Proteases Degrade Colonic Tight Junction Structure and Are Responsible for Abdominal Pain in Constipation-Predominant IBS

    Article • The American Journal of Gastroenterology, May 2013, Nature

    Dr Afifa Ait-Belgnaoui

  9. Tu1969 Probiotic (Probio'Stick®) Attenuates Hypothalamic-Pituitary-Adrenal (HPA) Axis Response to Chronic Psychological Stress Through an Improvement of Cellular Proliferation and Changes Gene Expression in the Brain Mice

    Article • Gastroenterology, May 2013, Elsevier

    Dr Thomas A Tompkins, Dr Afifa Ait-Belgnaoui

  10. 482 Intestinal Mucus Alterations Induced by Chronic Stress Are Linked to Changes in Mucin O-Glycan Structure Rather Than MUC2 Expression: Prevention by a Probiotic Treatment

    Article • Gastroenterology, May 2013, Elsevier

    Dr Afifa Ait-Belgnaoui

  11. Prevention of gut leakiness by a probiotic treatment leads to attenuated HPA response to an acute psychological stress in rats

    Article • Psychoneuroendocrinology, November 2012, Elsevier

    Dr Afifa Ait-Belgnaoui

  12. Sa2073 A Probiotic Treatment Attenuates Hypothalamic-Pituitary-Adrenal (HPA) Axis Response to Chronic Psychological Stress Through Improvement of Cellular Proliferation in the Hippocampus

    Article • Gastroenterology, May 2012, Elsevier

    Dr Thomas A Tompkins, Dr Afifa Ait-Belgnaoui

  13. 414 Short-Time Maternal Separation in Early Neonate Rats Markedly Increases Intestinal Permeability, Induces Bacterial Translocation and Impacts Gene Expression in the Liver

    Article • Gastroenterology, May 2012, Elsevier

    Dr Afifa Ait-Belgnaoui

  14. 1002 Fecal Supernatants From Constipation-Predominant Irritable Bowel Syndrome Patients Impair Epithelial Tight Junctions Integrity, Permeability, and Colonic Sensitivity in Mice: A Role for Cysteine-Proteases

    Article • Gastroenterology, May 2012, Elsevier

    Dr Afifa Ait-Belgnaoui

  15. T2031 Attenuation of the Hypothalamic-pituitary-Adrenal (HPA) Response to Stress by Lactobacillus Farciminis Treatment is Mediated Through a Prevention of Gut Leakiness and Associated Lipopolysaccharide Upload in Rats

    Article • Gastroenterology, May 2010, Elsevier

    Dr Afifa Ait-Belgnaoui

  16. Fecal proteases from diarrheic-IBS and ulcerative colitis patients exert opposite effect on visceral sensitivity in mice

    Article • Pain, July 2009, Wolters Kluwer Health

    Dr Afifa Ait-Belgnaoui

  17. Luminal Cathepsin G and Protease-Activated Receptor 4

    Article • American Journal Of Pathology, July 2009, Elsevier

    Dr Afifa Ait-Belgnaoui

  18. 1079 A Probiotic Treatment (Lactobacillus farciminis) Attenuates the Hypothalamic-Pituitary-Adrenal (HPA) Axis Response to Acute Stress in Rats

    Article • Gastroenterology, May 2009, Elsevier

    Dr Afifa Ait-Belgnaoui

  19. Lactobacillus farciministreatment attenuates stress-induced overexpression of Fos protein in spinal and supraspinal sites after colorectal distension in rats

    Article • Neurogastroenterology & Motility, May 2009, Wiley

    Dr Afifa Ait-Belgnaoui

  20. 106 Fecal Supernatants from Ulcerative Colitis Patients Display Antinociceptive Effects On Colorectal Sensitivity When Infused Intracolonically in Mice: Role of Cathepsin-G

    Article • Gastroenterology, May 2009, Elsevier

    Dr Afifa Ait-Belgnaoui

  21. P.35 Un traitement probiotique (Lactobacillus farciminis) atténue la réponse au stress de l’axe hypothalamo-hypophyso-surrénalien (HPA) chez le rat

    Article • Gastroentérologie Clinique et Biologique, March 2009, Elsevier

    Dr Afifa Ait-Belgnaoui

  22. P.301 La cathepsine-G des surnageants fécaux de patients RCH est responsable d’une hyposensibibité viscérale en réponse à la distension colorectale chez la souris : un effet médié par l’activation des récepteurs aux protéases de type IV

    Article • Gastroentérologie Clinique et Biologique, March 2009, Elsevier

    Dr Afifa Ait-Belgnaoui

  23. Brain Glucagon-Like Peptide 1 Signaling Controls the Onset of High-Fat Diet-Induced Insulin Resistance and Reduces Energy Expenditure

    Article • Endocrinology, October 2008, Endocrine Society

    Patrice D. Cani, Dr Afifa Ait-Belgnaoui

  24. Intracolonic infusion of faecal supernatant fraction from patients with diarrhoea-predominant irritable bowel syndrome evokes visceral hyperalgaesia in mice: reversal by a probiotic treatment

    Article • Proceedings of The Nutrition Society, May 2008, Cambridge University Press

    Dr Afifa Ait-Belgnaoui

  25. T1454 Intracolonic Infusion of Fecal Supernatants from Diarrhea-Predominant Irritable Bowel Syndrome Patients (IBS-D) Evokes Visceral Hyperalgesia in Mice: Reversal By a Probiotic Treatment Via a Decrease of Luminal Serine-Protease Activity

    Article • Gastroenterology, April 2008, Elsevier

    Dr Afifa Ait-Belgnaoui

  26. Increased faecal serine protease activity in diarrhoeic IBS patients: a colonic lumenal factor impairing colonic permeability and sensitivity

    Article • Gut, January 2008, BMJ

    Dr Afifa Ait-Belgnaoui

  27. Dexamethasone prevents visceral hyperalgesia but not colonic permeability increase induced by luminal protease-activated receptor-2 agonist in rats

    Article • Gut, August 2007, BMJ

    Dr Afifa Ait-Belgnaoui

  28. Improvement of an experimental colitis in rats by lactic acid bacteria producing superoxide dismutase

    Article • Inflammatory Bowel Diseases, November 2006, Oxford University Press (OUP)

    Dr Afifa Ait-Belgnaoui

  29. Lactobacillus farciminis treatment suppresses stress induced visceral hypersensitivity: a possible action through interaction with epithelial cell cytoskeleton contraction

    Article • Gut, September 2005, BMJ

    Dr Afifa Ait-Belgnaoui

  30. Acute stress-induced hypersensitivity to colonic distension depends upon increase in paracellular permeability: role of myosin light chain kinase

    Article • Pain, January 2005, Wolters Kluwer Health

    Dr Afifa Ait-Belgnaoui