All Stories

  1. Phenotypic and functional patterns of murine bone marrow-derived dendritic cells influenced by in vitro differentiation conditions

    Article • PLOS One, August 2026, PLOS

    Dr Adrian Onu

  2. Red Alga Porphyridium Supports High‐Yield Production of a Functional Chimeric Hepatitis B Surface Antigen With Strong Cellular and Humoral Immunogenicity

    Article • Plant Biotechnology Journal, July 2025, Wiley

    Dr Adrian Onu

  3. Humanized mouse model reveals the immunogenicity of Hepatitis B Virus vaccine candidates produced in CRISPR/Cas9-edited Nicotiana benthamiana

    Article • Frontiers in Immunology, April 2025, Frontiers

    Dr Adrian Onu

  4. The red alga Porphyridium as a host for molecular farming: Efficient production of immunologically active hepatitis C virus glycoprotein

    Article • Proceedings of the National Academy of Sciences, June 2024, Proceedings of the National Academy of Sciences

    Dr Adrian Onu

  5. Generation of a DSF-Guided Refolded Bacterially Expressed Hemagglutinin Ectodomain of Influenza Virus A/Puerto Rico/8/1934 H1N1 as a Model for Influenza Vaccine Antigens

    Article • Vaccines, September 2023, MDPI AG

    Dr Adrian Onu

  6. The “humanized” N‐glycosylation pathway in CRISPR/Cas9‐edited Nicotiana benthamiana significantly enhances the immunogenicity of a S/preS1 Hepatitis B Virus antigen and the virus‐neutralizing antibody response in vaccinated...

    Article • Plant Biotechnology Journal, March 2023, Wiley

    PhD Catalin Lazar, Dr Adrian Onu

  7. Comparison of truncated human angiotensin-converting enzyme 2 (hACE2) expression in pET28a(+) versus pET-SUMO vector and two Escherichia coli strains

    Article • Advances in Medical Sciences, March 2023, Elsevier

    Dr Adrian Onu

  8. Efficient cellular and humoral immune response and production of virus-neutralizing antibodies by the Hepatitis B Virus S/preS116-42 antigen

    Article • Frontiers in Immunology, July 2022, Frontiers

    PhD Catalin Lazar, Dr Adrian Onu

  9. Hepatitis C virus E2 envelope glycoprotein produced in Nicotiana benthamiana triggers humoral response with virus‐neutralizing activity in vaccinated mice

    Article • Plant Biotechnology Journal, June 2021, Wiley

    Dr Adrian Onu

  10. The Application of Single Use Bioreactors for the Production of a Carotenoids Mix, Mainly Torularhodin

    Article • Revista de Chimie, February 2019, Revista de Chimie SRL

    Dr Adrian Onu

  11. Oral administration of a chimeric Hepatitis B Virus S/preS1 antigen produced in lettuce triggers infection neutralizing antibodies in mice

    Article • Vaccine, September 2018, Elsevier

    PhD Catalin Lazar, Dr Adrian Onu

  12. A novel chimeric Hepatitis B virus S/preS1 antigen produced in mammalian and plant cells elicits stronger humoral and cellular immune response than the standard vaccine-constituent, S protein

    Article • Antiviral Research, August 2017, Elsevier

    Dr Adrian Onu, PhD Catalin Lazar

  13. Lettuce-produced hepatitis C virus E1E2 heterodimer triggers immune responses in mice and antibody production after oral vaccination

    Article • Plant Biotechnology Journal, June 2017, Wiley

    Dr Adrian Onu, PhD Catalin Lazar, Lisa Paruch

  14. Influenza Vaccine Manufacturing: Effect of Inactivation, Splitting and Site of Manufacturing. Comparison of Influenza Vaccine Production Processes

    Article • PLOS One, March 2016, PLOS

    Dr Adrian Onu

  15. Technology transfer of oil-in-water emulsion adjuvant manufacturing for pandemic influenza vaccine production in Romania: Preclinical evaluation of split virion inactivated H5N1 vaccine with adjuvant

    Article • Human Vaccines & Immunotherapeutics, November 2015, Taylor & Francis

    Dr Adrian Onu

  16. Technology transfer of oil-in-water emulsion adjuvant manufacturing for pandemic influenza vaccine production in Romania

    Article • Vaccine, March 2013, Elsevier

    Dr Adrian Onu

  17. Model and Kinetic Parameters Identification for Therapeutical Product Obtained According to the GMP Guidelines

    Article • Revista de Chimie, August 2008, Revista de Chimie SRL

    Dr Adrian Onu

  18. The cultivation of Pseudomonas aeruginosa for therapeutic purpose

    Article • Journal of Biotechnology, September 2007, Elsevier

    Dr Adrian Onu

  19. Regulatory Mechanisms Differ in UMP Kinases from Gram-negative and Gram-positive Bacteria

    Article • Journal of Biological Chemistry, December 2006, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Adrian Onu

  20. Matrix metalloproteinase-9 and its natural inhibitor TIMP-1 expressed or secreted by peripheral blood mononuclear cells from patients with systemic lupus erythematosus

    Article • Journal of Autoimmunity, June 2003, Elsevier

    Dr Adrian Onu

  21. Pycnogenol® efficacy in the treatment of systemic lupus erythematosus patients

    Article • Phytotherapy Research, October 2001, Wiley

    Dr Adrian Onu

  22. Dysregulation of p56 lck Kinase in Patients with Systemic Lupus Erythematosus

    Article • Autoimmunity, January 2001, Taylor & Francis

    Dr Adrian Onu

  23. p56 lck Activity and Expression in Peripheral Blood Lymphocytes from Patients with Systemic Lupus Erythematosus

    Article • Autoimmunity, January 1999, Taylor & Francis

    Dr Adrian Onu

  24. DIFFERENTIAL REGULATION OF HUMAN T LYMPHOBLAST FUNCTIONS BY IL-2 AND IL-15

    Article • Cytokine, July 1997, Elsevier

    Dr Adrian Onu

  25. Regulation of IL-15 secretion via the leader peptide of two IL-15 isoforms

    Article • The Journal of Immunology, January 1997, Oxford University Press (OUP)

    Dr Adrian Onu

  26. Suppression of cell-mediated and humoral immune responses by an interleukin-2-immunoglobulin fusion protein in mice.

    Article • Journal of Clinical Investigation, March 1996, American Society for Clinical Investigation

    Dr Adrian Onu

  27. Immunomodulation in Experimental and Clinical Nephrology Using Chimeric Proteins

    Article • Kidney and Blood Pressure Research, January 1996, Karger Publishers

    Dr Adrian Onu

  28. Tyrosine Phosphorylation in Peripheral Lymphocytes from Patients with Systemic Lupus Erythematosus

    Article • Autoimmunity, January 1996, Taylor & Francis

    Dr Adrian Onu

  29. Naturally Occurring Anti-Idiotypic Antibodies to Anti-Phosphotyrosine in Systemic Lupus Erythematosus Interact with SRC-Homology 2 Domains

    Article • Autoimmunity, January 1995, Taylor & Francis

    Francisco Ramos-Morales, Dr Adrian Onu

  30. Novel heterogeneity of the leucocyte common antigen (CD45): disulfide-bound heterodimers between CD45 and an 80 kDa polypeptide

    Article • Immunology Letters, April 1994, Elsevier

    Dr Adrian Onu, Dr Tamas Oravecz

  31. Identification of Anti-Idiotypic Antibodies to Anti-Phosphotyrosine Antibodies in Human Sera

    Article • Autoimmunity, January 1993, Taylor & Francis

    Dr Adrian Onu