All Stories

  1. Quantitative proteomics identifies tumour matrisome signatures in patients with non-small cell lung cancer

    Article • Frontiers in Oncology, June 2023, Frontiers

    Dr Adam Byron

  2. FAK suppresses antigen processing and presentation to promote immune evasion in pancreatic cancer

    Article • Gut, March 2023, BMJ

    Dr Adam Byron

  3. Mena regulates nesprin-2 to control actin–nuclear lamina associations, trans-nuclear membrane signalling and gene expression

    Article • Nature Communications, March 2023, Springer Science + Business Media

    Dr Adam Byron

  4. Endoglin and MMP14 Contribute to Ewing Sarcoma Spreading by Modulation of Cell–Matrix Interactions

    Article • International Journal of Molecular Sciences, August 2022, MDPI AG

    Dr Adam Byron

  5. Characterisation of a nucleo-adhesome

    Article • Nature Communications, June 2022, Springer Science + Business Media

    Dr Adam Byron

  6. Characterisation of the Stromal Microenvironment in Lobular Breast Cancer

    Article • Cancers, February 2022, MDPI AG

    Dr Adam Byron

  7. Characterisation of a nucleo-adhesome

    Article • August 2021, Cold Spring Harbor Laboratory Press

    Dr Adam Byron

  8. Multicenter reverse-phase protein array data integration

    Article • August 2021, Cold Spring Harbor Laboratory Press

    Dr Adam Byron

  9. Glioblastomas acquire myeloid-affiliated transcriptional programs via epigenetic immunoediting to elicit immune evasion

    Article • Cell, April 2021, Elsevier

    Dr Adam Byron

  10. mTORC1 activity is supported by spatial association with focal adhesions

    Article • Journal of Cell Biology, February 2021, Rockefeller University Press

    Dr Adam Byron

  11. FAK regulates IL-33 expression by controlling chromatin accessibility at c-Jun motifs

    Article • Scientific Reports, January 2021, Springer Science + Business Media

    Dr Adam Byron

  12. Integrative analysis of multi-platform reverse-phase protein array data for the pharmacodynamic assessment of response to targeted therapies

    Article • Scientific Reports, December 2020, Springer Science + Business Media

    Dr Adam Byron

  13. Network Analysis of Integrin Adhesion Complexes

    Article • November 2020, Springer Science + Business Media

    Dr Adam Byron

  14. Structural basis of Focal Adhesion Kinase activation on lipid membranes

    Article • The EMBO Journal, August 2020, EMBO

    Dr Adam Byron

  15. Basement membrane ligands initiate distinct signalling networks to direct cell shape

    Article • Matrix Biology, August 2020, Elsevier

    Dr Adam Byron

  16. The autophagy protein Ambra1 regulates gene expression by supporting novel transcriptional complexes

    Article • Journal of Biological Chemistry, August 2020, Elsevier

    Dr Adam Byron

  17. Novel roles of PRK1 and PRK2 in cilia and cancer biology

    Article • Scientific Reports, March 2020, Springer Science + Business Media

    Dr Adam Byron

  18. A Synergistic Anticancer FAK and HDAC Inhibitor Combination Discovered by a Novel Chemical–Genetic High-Content Phenotypic Screen

    Article • Molecular Cancer Therapeutics, February 2020, American Association for Cancer Research (AACR)

    Dr Adam Byron

  19. Evaluation of Gene Expression Data From Cybrids and Tumours Highlights Elevated NDRG1-Driven Proliferation in Triple-Negative Breast Cancer

    Article • Breast Cancer Basic and Clinical Research, January 2020, SAGE Publications

    Dr Adam Byron

  20. Regulation of Cell-Matrix Adhesion Networks: Insights from Proteomics

    Article • January 2020, Springer Science + Business Media

    Dr Adam Byron

  21. Integrative analysis of multi-platform reverse-phase protein array data for the pharmacodynamic assessment of response to targeted therapies

    Article • September 2019, Cold Spring Harbor Laboratory Press

    Dr Adam Byron

  22. Reproducibility and Crossplatform Validation of Reverse-Phase Protein Array Data

    Article • January 2019, Springer Science + Business Media

    Dr Adam Byron

  23. E-cadherin loss induces targetable autocrine activation of growth factor signalling in lobular breast cancer

    Article • Scientific Reports, October 2018, Springer Science + Business Media

    Dr Adam Byron

  24. Trafficking of Adhesion and Growth Factor Receptors and Their Effector Kinases

    Article • Annual Review of Cell and Developmental Biology, October 2018, Annual Reviews

    Dr Adam Byron

  25. Eps8 is a convergence point integrating EGFR and integrin trafficking and crosstalk

    Article • September 2018, Cold Spring Harbor Laboratory Press

    Dr Adam Byron

  26. Kindlin-1 Promotes Pulmonary Breast Cancer Metastasis

    Article • Cancer Research, March 2018, American Association for Cancer Research (AACR)

    Dr Adam Byron

  27. Proteomic Profiling of Integrin Adhesion Complex Assembly

    Article • January 2018, Springer Science + Business Media

    Dr Adam Byron

  28. IL-33 and ST2 mediate FAK-dependent antitumor immune evasion through transcriptional networks

    Article • Science Signaling, December 2017, American Association for the Advancement of Science

    Dr Adam Byron

  29. Nuclear FAK and Runx1 Cooperate to Regulate IGFBP3, Cell-Cycle Progression, and Tumor Growth

    Article • Cancer Research, October 2017, American Association for Cancer Research (AACR)

    Dr Adam Byron

  30. Ambra1 spatially regulates Src activity and Src/FAK-mediated cancer cell invasion via trafficking networks

    Article • eLife, March 2017, eLife

    Dr Adam Byron

  31. Improved LC-MS chromatographic alignment increases the accuracy of label-free quantitative proteomics: Comparison of spectral counting versus ion intensity-based proteomic quantification strategies

    Article • February 2017, Cold Spring Harbor Laboratory Press

    Dr Adam Byron

  32. Characterization of the Phospho-Adhesome by Mass Spectrometry-Based Proteomics

    Article • January 2017, Springer Science + Business Media

    Dr Adam Byron

  33. Clustering and Network Analysis of Reverse Phase Protein Array Data

    Article • January 2017, Springer Science + Business Media

    Dr Adam Byron

  34. Ligand-induced Epitope Masking

    Article • Journal of Biological Chemistry, August 2016, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Adam Byron

  35. Adhesion protein networks reveal functions proximal and distal to cell-matrix contacts

    Article • Current Opinion in Cell Biology, April 2016, Elsevier

    Dr Adam Byron

  36. Identification of novel pathways linking epithelial-to-mesenchymal transition with resistance to HER2-targeted therapy

    Article • Oncotarget, February 2016, Impact Journals, LLC

    Dr Adam Byron

  37. Definition of a consensus integrin adhesome and its dynamics during adhesion complex assembly and disassembly

    Article • Nature, October 2015, Nature

    Dr Adam Byron

  38. Proteomic analysis of integrin‐associated complexes from mesenchymal stem cells

    Article • PROTEOMICS - CLINICAL APPLICATIONS, September 2015, Wiley

    Dr Adam Byron

  39. Nuclear FAK Controls Chemokine Transcription, Tregs, and Evasion of Anti-tumor Immunity

    Article • Cell, September 2015, Elsevier

    Dr Adam Byron

  40. Genetic Background is a Key Determinant of Glomerular Extracellular Matrix Composition and Organization

    Article • Journal of the American Society of Nephrology, April 2015, American Society of Nephrology

    Dr Adam Byron

  41. Isolation of Integrin‐Based Adhesion Complexes

    Article • Current Protocols in Cell Biology, March 2015, Wiley

    Dr Adam Byron, Dr Adam Byron

  42. Defining the phospho-adhesome through the phosphoproteomic analysis of integrin signalling

    Article • Nature Communications, February 2015, Springer Science + Business Media

    Dr Adam Byron, Dr Adam Byron

  43. A proteomic approach reveals integrin activation state-dependent control of microtubule cortical targeting

    Article • Nature Communications, January 2015, Springer Science + Business Media

    Dr Adam Byron, Dr Adam Byron, Christopher Chen

  44. Microtubule-Dependent Modulation of Adhesion Complex Composition

    Article • PLOS One, December 2014, PLOS

    Dr Adam Byron, Dr Adam Byron

  45. Exploring mechanisms of acquired resistance to HER2 (human epidermal growth factor receptor 2)-targeted therapies in breast cancer

    Article • Biochemical Society Transactions, August 2014, Portland Press Ltd.

    Dr Adam Byron, Dr Adam Byron

  46. Global Analysis Reveals the Complexity of the Human Glomerular Extracellular Matrix

    Article • Journal of the American Society of Nephrology, May 2014, Wolters Kluwer Health

    Dr Adam Byron, Dr Adam Byron

  47. Glomerular Cell Cross-Talk Influences Composition and Assembly of Extracellular Matrix

    Article • Journal of the American Society of Nephrology, May 2014, Wolters Kluwer Health

    Dr Adam Byron, Dr Adam Byron

  48. Rac1 is deactivated at integrin activation sites through an IQGAP1-filamin-A-RacGAP1 pathway

    Article • Journal of Cell Science, July 2013, The Company of Biologists

    Dr Adam Byron, Dr Adam Byron, Christopher Chen

  49. The effect of peptide adsorption on signal linearity and a simple approach to improve reliability of quantification

    Article • Journal of Proteomics, June 2013, Elsevier

    Dr Adam Byron, Dr Adam Byron

  50. Comparative Proteomic Analysis of Supportive and Unsupportive Extracellular Matrix Substrates for Human Embryonic Stem Cell Maintenance

    Article • Journal of Biological Chemistry, May 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Adam Byron, Simon Borg-Bartolo, Dr Adam Byron

  51. Defining the extracellular matrix using proteomics

    Article • International Journal of Experimental Pathology, February 2013, Wiley

    Dr Adam Byron, Dr Adam Byron

  52. Alternative cellular roles for proteins identified using proteomics

    Article • Journal of Proteomics, July 2012, Elsevier

    Dr Adam Byron, Dr Adam Byron

  53. Proteomic analysis of α4β1 integrin adhesion complexes reveals α‐subunit‐dependent protein recruitment

    Article • PROTEOMICS, July 2012, Wiley

    Dr Adam Byron, Dr Adam Byron

  54. Proteomic analysis of extracellular matrix from the hepatic stellate cell line LX-2 identifies CYR61 and Wnt-5a as novel constituents of fibrotic liver

    Article • Journal of Proteome Research, June 2012, American Chemical Society (ACS)

    Dr Adam Byron, Dr Adam Byron

  55. A Syndecan-4 Hair Trigger Initiates Wound Healing through Caveolin- and RhoG-Regulated Integrin Endocytosis

    Article • Developmental Cell, October 2011, Elsevier

    Dr Adam Byron, Dr Adam Byron

  56. Analyzing the Anatomy of Integrin Adhesions

    Article • Science Signaling, April 2011, American Association for the Advancement of Science

    Dr Adam Byron, Dr Adam Byron

  57. Proteomic Analysis of Integrin Adhesion Complexes

    Article • Science Signaling, March 2011, American Association for the Advancement of Science

    Dr Adam Byron, Dr Adam Byron

  58. Adhesion signalling complexes

    Article • Current Biology, December 2010, Elsevier

    Dr Adam Byron, Dr Adam Byron

  59. Mapping the ligand-binding pocket of integrin α5β1 using a gain-of-function approach

    Article • Biochemical Journal, December 2009, Portland Press Ltd.

    Dr Adam Byron, Dr Adam Byron

  60. Anti-integrin monoclonal antibodies

    Article • Journal of Cell Science, November 2009, The Company of Biologists

    Dr Adam Byron, Dr Adam Byron

  61. Proteomic Analysis of Integrin-Associated Complexes Identifies RCC2 as a Dual Regulator of Rac1 and Arf6

    Article • Science Signaling, September 2009, American Association for the Advancement of Science

    Dr Adam Byron, Dr Adam Byron

  62. Giving off mixed signals—Distinct functions of α5β1 and αvβ3 integrins in regulating cell behaviour

    Article • IUBMB Life, June 2009, Wiley

    Dr Adam Byron, Dr Adam Byron

  63. Integrin ligands at a glance

    Article • Journal of Cell Science, October 2006, The Company of Biologists

    Dr Adam Byron, Dr Adam Byron

  64. Utilisation of the budding yeast Saccharomyces cerevisiae for the generation and isolation of non‐lethal ricin A chain variants

    Article • Yeast, December 2005, Wiley

    Dr Adam Byron, Dr Adam Byron