All Stories

  1. Excessive homozygosity identified by chromosomal microarray at a known GCDH mutation locus correlates with brain MRI abnormalities in an infant with glutaric aciduria
  2. A multicenter clinical exome study in unselected cohorts from a consanguineous population of Saudi Arabia demonstrated a high diagnostic yield
  3. High expression of matrix metalloproteinases: MMP-2 and MMP-9 predicts poor survival outcome in colorectal carcinoma
  4. The evaluation of DiGeorge syndrome gene deletion using molecular cytogenetic techniques
  5. Targeting the disturbed redox equilibrium in chronic lymphocytic leukemia by novel reactive oxygen species-catalytic ‘sensor/effector’ compounds
  6. Synthesis and Selective Anticancer Activity of Organochalcogen Based Redox Catalysts
  7. Pharmacologic interception in T-cell leukemia 1A associated pathways as a treatment rationale for chronic lymphocytic leukemia
  8. Elevated PIN1 expression by C/EBPα-p30 blocks C/EBPα-induced granulocytic differentiation through c-Jun in AML
  9. Cell-cycle regulator E2F1 and microRNA-223 comprise an autoregulatory negative feedback loop in acute myeloid leukemia
  10. Proteomic identification of the MYST domain histone acetyltransferase TIP60 (HTATIP) as a co-activator of the myeloid transcription factor C/EBPα
  11. Target proteins of C/EBP p30 in AML: C/EBP p30 enhances sumoylation of C/EBP p42 via up-regulation of Ubc9
  12. Proteomic analysis of acute promyelocytic leukemia: PML-RARα leads to decreased phosphorylation of OP18 at serine 63
  13. Elevated c-Jun expression in acute myeloid leukemias inhibits C/EBPα DNA binding via leucine zipper domain interaction
  14. Downregulation of c-Jun expression and cell cycle regulatory molecules in acute myeloid leukemia cells upon CD44 ligation
  15. Proteomic analysis of transcription factor interactions in myeloid stem cell development and leukaemia