All Stories

  1. Identification of prognostic variables in patients with recurrent head and neck squamous cell carcinoma treated with salvage surgery: Implications for treatment with immunotherapy

    Article • Oral Oncology, April 2026, Elsevier

    Dr Xavier León

  2. Neuropilin-2 upregulation by stromal TGFβ1 induces lung disseminated tumor cells dormancy escape and promotes metastasis outgrowth

    Article • Neoplasia, October 2025, Elsevier

    Dr Xavier León

  3. Opening of a phase Ib/II study to investigate the safety and efficacy of Afatinib in patients with Fanconi anemia and unresectable locally advanced or metastatic head and neck squamous cell carcinoma

    Article • BMC Cancer, August 2025, Springer Science + Business Media

    Dr Xavier León

  4. Endoscopic-assisted maxillectomy: our experience in tumours affecting the posterior wall of the maxillary sinus

    Article • The Journal of Laryngology & Otology, July 2025, Cambridge University Press

    Dr Xavier León

  5. Prognostic value of pretreatment peripheral blood biomarkers in patients with head and neck squamous cell carcinoma treated with chemo/bioradiotherapy

    Article • Revista de Oncología, May 2025, Springer Science + Business Media

    Dr Xavier León

  6. Relación de la infección por el virus del papiloma humano con la aparición de segundas neoplasias y su repercusión pronóstica en los pacientes con carcinoma de orofaringe

    Article • Acta Otorrinolaringológica Española, April 2025, Elsevier

    Dr Xavier León

  7. Transcriptional Expression of SLC2A3 and SDHA Predicts the Risk of Local Tumor Recurrence in Patients with Head and Neck Squamous Cell Carcinomas Treated Primarily with Radiotherapy or Chemoradiotherapy

    Article • International Journal of Molecular Sciences, March 2025, MDPI AG

    Dr Xavier León

  8. Lower lip reconstruction with the Karapandzic flap or the Colmenero flap: Description of results

    Article • Acta Otorrinolaringologica (English Edition), March 2025, Elsevier

    Dr Xavier León

  9. Análisis de la supervivencia de los pacientes con tumores malignos de cabeza y cuello diagnosticados durante la pandemia de COVID-19

    Article • Acta Otorrinolaringológica Española, February 2025, Elsevier

    Dr Xavier León

  10. Survival of patients with malignant head and neck tumors diagnosed during the COVID-19 pandemic

    Article • Acta Otorrinolaringologica (English Edition), February 2025, Elsevier

    Dr Xavier León

  11. PATH classification: a proposal for patients with HNSCC treated with salvage surgery

    Article • European Archives of Oto-Rhino-Laryngology, September 2024, Springer Science + Business Media

    Dr Xavier León

  12. Predictive capacity for local disease control of neogenin-1 (NEO1) transcriptional expression in patients with head and neck squamous cell carcinoma

    Article • Revista de Oncología, June 2024, Springer Science + Business Media

    Dr Xavier León

  13. Results of surgical treatment of lymph node metastases in patients with cutaneous squamous cell carcinoma of the head and neck

    Article • Acta Otorrinolaringologica (English Edition), May 2024, Elsevier

    Dr Xavier León

  14. Descending necrotizing mediastinitis: key points to reduce the high associated mortality in a consecutive case series

    Article • Mediastinum, March 2024, AME Publishing Company

    Dr Xavier León

  15. Prognostic capacity of PIV (pan-immune-inflammation value) in patients with head and neck squamous cell carcinoma

    Article • Acta Otorrinolaringologica (English Edition), March 2024, Elsevier

    Dr Xavier León

  16. Surgical treatment of 186 sinonasal inverted papillomas and analysis of the immunohistochemical and molecular features associated with recurrences

    Article • American Journal of Otolaryngology, March 2024, Elsevier

    Dr Xavier León

  17. Survivin/BIRC5 as a novel molecular effector at the crossroads of glucose metabolism and radioresistance in head and neck squamous cell carcinoma

    Article • Head & Neck, February 2024, Wiley

    Dr Xavier León

  18. External validation of the GETTEC algorithm for elective neck dissection in patients candidates for salvage total laryngectomy

    Article • Oral Oncology, February 2024, Elsevier

    Dr Xavier León

  19. Oncological results of salvage treatment in patients with oropharynx carcinoma treated with radiotherapy

    Article • Acta Otorrinolaringologica (English Edition), January 2024, Elsevier

    Dr Xavier León

  20. Host-related indexes in head and neck cancer

    Article • Current Opinion in Otolaryngology & Head & Neck Surgery, December 2023, Wolters Kluwer Health

    Dr Xavier León

  21. Predictive capacity of FAT1 transcriptional expression in patients with head and neck squamous cell carcinomas treated with radiotherapy

    Article • Acta Otorrinolaringologica (English Edition), November 2023, Elsevier

    Dr Xavier León

  22. Relationship between transcriptional expression of pyruvate dehydrogenase and local control of disease in patients with oral cavity carcinomas

    Article • Acta Otorrinolaringologica (English Edition), November 2023, Elsevier

    Dr Xavier León

  23. Second esophageal neoplasms after head and neck index tumor: Incidence, risk factors and prognosis

    Article • Acta Otorrinolaringologica (English Edition), November 2023, Elsevier

    Dr Xavier León

  24. Is long-term screening for lung cancer justified in patients with head and neck carcinoma?

    Article • Acta Otorrinolaringologica (English Edition), September 2023, Elsevier

    Dr Xavier León

  25. Association between maximum standarised uptake value (SUV) and local control in patients with oropharyngeal carcinoma treated with radiotherapy

    Article • Acta Otorrinolaringologica (English Edition), July 2023, Elsevier

    Dr Xavier León

  26. Results of radiotherapy in oropharyngeal carcinomas

    Article • Acta Otorrinolaringologica (English Edition), May 2023, Elsevier

    Dr Xavier León

  27. Facial nerve palsy following parotid gland surgery: A machine learning prediction outcome approach

    Article • World Journal of Otorhinolaryngology - Head and Neck Surgery, March 2023, Wiley

    Dr Xavier León

  28. Differential characteristics of patients with squamous cell carcinoma of the head and neck with no history of tobacco or alcohol use

    Article • Acta Otorrinolaringologica (English Edition), January 2023, Elsevier

    Dr Xavier León

  29. External validation of the H‐index (host index) in patients with head and neck squamous cell carcinomas

    Article • Head & Neck, October 2022, Wiley

    Dr Xavier León

  30. Concordance of p16INK4a and E6*I mRNA among HPV-DNA-Positive Oropharyngeal, Laryngeal, and Oral Cavity Carcinomas from the ICO International Study

    Article • Cancers, August 2022, MDPI AG

    Dr Xavier León

  31. Prognostic capacity of the transcriptional expression of lactate dehydrogenase A in patients with head and neck squamous cell carcinoma

    Article • Head & Neck, August 2022, Wiley

    Dr Xavier León

  32. Prognostic value of transcriptional expression of fibronectin type III domain-containing 4 (FNDC4) in head and neck carcinoma patients treated with chemoradiotherapy

    Article • Revista de Oncología, June 2022, Springer Science + Business Media

    Dr Xavier León

  33. The extended SCIP flap: an anatomical and clinical study of a new SCIP flap design

    Article • Journal of Plastic Reconstructive & Aesthetic Surgery, June 2022, Elsevier

    Dr Xavier León

  34. Semaphorin-3F/Neuropilin-2 Transcriptional Expression as a Predictive Biomarker of Occult Lymph Node Metastases in HNSCC

    Article • Cancers, April 2022, MDPI AG

    Dr Xavier León

  35. A Novel CXCR4-Targeted Diphtheria Toxin Nanoparticle Inhibits Invasion and Metastatic Dissemination in a Head and Neck Squamous Cell Carcinoma Mouse Model

    Article • Pharmaceutics, April 2022, MDPI AG

    Dr Xavier León

  36. CXCR4-targeted nanotoxins induce GSDME-dependent pyroptosis in head and neck squamous cell carcinoma

    Article • Journal of Experimental & Clinical Cancer Research, February 2022, Springer Science + Business Media

    Dr Xavier León

  37. Pharyngocutaneous fistula in irradiated patients: systematic review and our experience

    Article • The Journal of Laryngology & Otology, January 2022, Cambridge University Press

    Dr Xavier León

  38. Relationship between the transcriptional expression of PIM1 and local control in patients with head and neck squamous cell carcinomas treated with radiotherapy

    Article • European Archives of Oto-Rhino-Laryngology, January 2022, Springer Science + Business Media

    Dr Xavier León

  39. Causes of long-term mortality in patients with head and neck squamous cell carcinomas

    Article • European Archives of Oto-Rhino-Laryngology, December 2021, Springer Science + Business Media

    Dr Xavier León

  40. Anatomic mapping of the collateral branches of the external carotid artery with regard to daily clinical practice

    Article • Annals of Anatomy - Anatomischer Anzeiger, November 2021, Elsevier

    Dr Xavier León

  41. Capacidad predictiva de la expresión de IL-8 en pacientes con carcinomas escamosos de cabeza y cuello tratados con radioterapia o quimio-radioterapia

    Article • Acta Otorrinolaringológica Española, November 2021, Elsevier

    Dr Xavier León

  42. Differential Characteristics of Patients With Squamous Cell Carcinoma of the Head and Neck According to Gender

    Article • Acta Otorrinolaringologica (English Edition), November 2021, Elsevier

    Dr Xavier León

  43. Predictive capacity of IL-8 expression in head and neck squamous carcinoma patients treated with radiotherapy or chemoradiotherapy

    Article • Acta Otorrinolaringologica (English Edition), November 2021, Elsevier

    Dr Xavier León

  44. Low skeletal muscle mass assessed directly from the 3rd cervical vertebra can predict pharyngocutaneous fistula risk after total laryngectomy in the male population

    Article • European Archives of Oto-Rhino-Laryngology, October 2021, Springer Science + Business Media

    Dr Xavier León

  45. Self-assembling protein nanocarrier for selective delivery of cytotoxic polypeptides to CXCR4+ head and neck squamous cell carcinoma tumors

    Article • Acta Pharmaceutica Sinica B, October 2021, Elsevier

    Dr Xavier León

  46. COVID-19 Pandemic and its Impact on the Management of Head and Neck Cancer in the Spanish Healthcare System.

    Article • International Archives of Otorhinolaryngology, October 2021, Thieme Publishing Group

    Dr Xavier León

  47. The carotid axis revisited

    Article • Scientific Reports, July 2021, Springer Science + Business Media

    Dr Xavier León

  48. Head and neck squamous cell carcinoma in cigar smokers. Distinctive epidemiological and prognostic characteristics

    Article • Acta Otorrinolaringologica (English Edition), July 2021, Elsevier

    Dr Xavier León

  49. Predictive value of transcriptional expression of Krüppel-like factor-6 (KLF6) in head and neck carcinoma patients treated with radiotherapy

    Article • Revista de Oncología, June 2021, Springer Science + Business Media

    Dr Xavier León

  50. Prognostic value of the nodal yield in elective neck dissections in patients with head and neck carcinomas

    Article • European Archives of Oto-Rhino-Laryngology, May 2021, Springer Science + Business Media

    Dr Xavier León

  51. Preservación de órgano en pacientes con tumores avanzados de laringe. Resultados de la quimioterapia de inducción versus quimio-radioterapia en la práctica clínica real

    Article • Acta Otorrinolaringológica Española, May 2021, Elsevier

    Dr Xavier León

  52. Succinate Pathway in Head and Neck Squamous Cell Carcinoma: Potential as a Diagnostic and Prognostic Marker

    Article • Cancers, April 2021, MDPI AG

    Dr Xavier León

  53. Trends in disease-specific survival of head and neck squamous cell carcinoma patients treated in a single institution over a 30-year period

    Article • Oral Oncology, April 2021, Elsevier

    Dr Xavier León

  54. The Effect of Perioperative Blood Transfusions on Microvascular Anastomoses

    Article • Journal of Clinical Medicine, March 2021, MDPI AG

    Dr Xavier León

  55. The aspartate aminotransaminase/alanine aminotransaminase (De Ritis) ratio predicts sensitivity to radiotherapy in head and neck carcinoma patients

    Article • Head & Neck, March 2021, Wiley

    Dr Xavier León

  56. Resultados oncológicos del tratamiento de rescate en pacientes con carcinomas de hipofaringe

    Article • Acta Otorrinolaringológica Española, March 2021, Elsevier

    Dr Xavier León

  57. Prognostic capacity of the weighted lymph node ratio in head and neck squamous cell carcinoma patients treated with salvage neck dissection

    Article • European Archives of Oto-Rhino-Laryngology, January 2021, Springer Science + Business Media

    Dr Xavier León

  58. Preservación de órgano tras un tratamiento con quimioterapia de inducción en pacientes con carcinomas localmente avanzados (T3-T4) de cavidad oral y orofaringe

    Article • Acta Otorrinolaringológica Española, January 2021, Elsevier

    Dr Xavier León

  59. Salvage surgery in head and neck cancer: External validation of predictors of disease-specific survival

    Article • Oral Oncology, October 2020, Elsevier

    Dr Xavier León

  60. Traqueotomía en pacientes COVID-19: un procedimiento necesario de alto riesgo. Experiencia de dos centros

    Article • Archivos de Bronconeumología (English Edition), October 2020, Elsevier

    Dr Xavier León

  61. Capacidad pronóstica de la densidad ganglionar en los carcinomas escamosos de cabeza y cuello

    Article • Acta Otorrinolaringológica Española, September 2020, Elsevier

    Dr Xavier León

  62. Un caso de sialometaplasia necrosante

    Article • Acta Otorrinolaringológica Española, September 2020, Elsevier

    Dr Xavier León

  63. Long-term outcomes of induction chemotherapy followed by chemoradiotherapy vs chemoradiotherapy alone as treatment of unresectable head and neck cancer: follow-up of the Spanish Head and Neck Cancer Group (TTCC) 2503 Trial

    Article • Revista de Oncología, August 2020, Springer Science + Business Media

    Dr Xavier León

  64. Epidemiology of human papillomavirus-related oropharyngeal cancer in a classically low-burden region of southern Europe

    Article • Scientific Reports, August 2020, Springer Science + Business Media

    Dr Xavier León

  65. Circulating microRNAs modulating glycolysis as non-invasive prognostic biomarkers of HNSCC

    Article • European Archives of Oto-Rhino-Laryngology, July 2020, Springer Science + Business Media

    Dr Xavier León

  66. Oral cavity colon adenocarcinoma metastases: case report with surgical approach and review of more than 30 years literature

    Article • Oral and Maxillofacial Surgery, July 2020, Springer Science + Business Media

    Dr Xavier León

  67. Pharyngeal closure after a total laryngectomy: mechanical versus manual technique

    Article • The Journal of Laryngology & Otology, July 2020, Cambridge University Press

    Dr Xavier León

  68. Significado pronóstico de los niveles de albúmina previos al tratamiento en los pacientes con carcinoma escamoso de cabeza y cuello

    Article • Acta Otorrinolaringológica Española, July 2020, Elsevier

    Dr Xavier León

  69. Valoración de la capacidad pronóstica de la afectación ganglionar de los pacientes con carcinoma de orofaringe en función del estatus HPV

    Article • Acta Otorrinolaringológica Española, July 2020, Elsevier

    Dr Xavier León

  70. Weighted lymph node ratio: New tool in the assessment of postoperative staging of the neck dissection in HPV ‐negative head and neck squamous cell carcinoma patients

    Article • Head & Neck, June 2020, Wiley

    Dr Xavier León

  71. Análisis de la supervivencia específica y el control local mediante un análisis de partición recursiva en pacientes con carcinomas de cabeza y cuello

    Article • Acta Otorrinolaringológica Española, May 2020, Elsevier

    Dr Xavier León

  72. Does age influence disease‐specific survival in patients with squamous cell carcinomas of the head and neck?

    Article • Journal of Surgical Oncology, March 2020, Wiley

    Dr Xavier León

  73. Resultados oncológicos de la laringectomía de rescate en pacientes con carcinomas escamosos de laringe

    Article • Acta Otorrinolaringológica Española, March 2020, Elsevier

    Dr Xavier León

  74. Riesgo de aparición de segundas neoplasias y neoplasias sucesivas en pacientes con un tumor índice de cabeza y cuello

    Article • Acta Otorrinolaringológica Española, January 2020, Elsevier

    Dr Xavier León

  75. Pretreatment peripheral blood leukocytes are independent predictors of survival in oral cavity cancer

    Article • Cancer, December 2019, Wiley

    Dr Xavier León

  76. Prognostic capacity of Systemic Inflammation Response Index (SIRI) in patients with head and neck squamous cell carcinoma

    Article • Head & Neck, November 2019, Wiley

    Dr Xavier León

  77. Pacientes con carcinoma localmente avanzado de hipofaringe. Resultados a lo largo de un periodo de 30 años

    Article • Acta Otorrinolaringológica Española, November 2019, Elsevier

    Dr Xavier León

  78. Infección parotídea por Mycobacterium malmoense

    Article • Enfermedades Infecciosas y Microbiología Clínica, October 2019, Elsevier

    Dr Xavier León

  79. Características epidemiológicas de los pacientes con carcinomas escamosos de cabeza y cuello. Resultados de un registro hospitalario

    Article • Acta Otorrinolaringológica Española, September 2019, Elsevier

    Dr Xavier León

  80. Absence of disruptive TP53 mutations in high‐risk human papillomavirus‐driven neck squamous cell carcinoma of unknown primary

    Article • Head & Neck, August 2019, Wiley

    Dr Xavier León

  81. Indications and results of extended total laryngectomy with en-bloc resection of overlying cervical skin

    Article • European Archives of Oto-Rhino-Laryngology, July 2019, Springer Science + Business Media

    Dr Xavier León

  82. Repair of post-laryngectomy pharyngocutaneous fistulas using a pectoralis major flap

    Article • Brazilian Journal of Otorhinolaryngology, May 2019, Elsevier

    Dr Xavier León

  83. The combined use of EFS, GPX2, and SPRR1A expression could distinguish favorable from poor clinical outcome among epithelial‐like head and neck carcinoma subtypes

    Article • Head & Neck, January 2019, Wiley

    Dr Xavier León

  84. Competing mortality in oropharyngeal carcinoma according to human papillomavirus status

    Article • Head & Neck, December 2018, Wiley

    Dr Xavier León

  85. Effect of serpinE1 overexpression on the primary tumor and lymph node, and lung metastases in head and neck squamous cell carcinoma

    Article • Head & Neck, December 2018, Wiley

    Dr Xavier León

  86. The Use of HPV16-E5, EGFR, and pEGFR as Prognostic Biomarkers for Oropharyngeal Cancer Patients

    Article • Frontiers in Oncology, December 2018, Frontiers

    Dr Xavier León

  87. Distinctive Expression and Amplification of Genes at 11q13 in Relation to HPV Status with Impact on Survival in Head and Neck Cancer Patients

    Article • Journal of Clinical Medicine, December 2018, MDPI AG

    Dr Xavier León

  88. Pharyngocutaneous fistula after total laryngectomy: multivariate analysis of risk factors and a severity-based classification proposal

    Article • European Archives of Oto-Rhino-Laryngology, November 2018, Springer Science + Business Media

    Dr Xavier León

  89. Prognostic role of extracapsular spread in planned neck dissection after chemoradiotherapy

    Article • Head & Neck, October 2018, Wiley

    Dr Xavier León

  90. Carcinoma análogo del secretor mamario de glándulas salivales: a propósito de un caso clínico

    Article • Acta Otorrinolaringológica Española, September 2018, Elsevier

    Dr Xavier León

  91. Significado pronóstico de la extensión extranodal en pacientes con carcinomas escamosos de cabeza y cuello cN0 con metástasis ganglionares ocultas

    Article • Acta Otorrinolaringológica Española, May 2018, Elsevier

    Dr Xavier León

  92. HPV-relatedness definitions for classifying HPV-related oropharyngeal cancer patient do impact on TNM classification and patients’ survival

    Article • PLOS One, April 2018, PLOS

    Dr Xavier León

  93. Elective neck dissection during salvage surgery after radiotherapy in patients with head and neck squamous cell carcinoma

    Article • Acta Otorhinolaryngologica Italica, April 2018, Pacini Editore

    Dr Xavier León

  94. Impacto de la laringectomía total en la situación laboral

    Article • Acta Otorrinolaringológica Española, March 2018, Elsevier

    Dr Xavier León

  95. Double positivity for HPV-DNA/p16ink4a is the biomarker with strongest diagnostic accuracy and prognostic value for human papillomavirus related oropharyngeal cancer patients

    Article • Oral Oncology, March 2018, Elsevier

    Dr Xavier León

  96. Postoperative staging of the neck dissection using extracapsular spread and lymph node ratio as prognostic factors in HPV-negative head and neck squamous cell carcinoma patients

    Article • Oral Oncology, February 2018, Elsevier

    Ms Cristina Valero, Dr Xavier León

  97. Prognostic value of CD45 transcriptional expression in head and neck cancer

    Article • European Archives of Oto-Rhino-Laryngology, November 2017, Springer Science + Business Media

    Dr Xavier León

  98. Prognostic relevance of insulin resistance on disease-free survival in head and neck squamous cell carcinomas: Preliminary results

    Article • Head & Neck, September 2017, Wiley

    Dr Xavier León

  99. Validation of the pathological classification of lymph node metastasis for head and neck tumors according to the 8th edition of the TNM Classification of Malignant Tumors

    Article • Oral Oncology, July 2017, Elsevier

    Dr Xavier León

  100. Modifications in the treatment of advanced laryngeal cancer throughout the last 30 years

    Article • European Archives of Oto-Rhino-Laryngology, June 2017, Springer Science + Business Media

    Dr Xavier León

  101. The prognostic value of pretreatment platelet count in patients with head and neck squamous cell carcinoma

    Article • Auris Nasus Larynx, June 2017, Elsevier

    Ms Cristina Valero, Dr Xavier León

  102. Relationship between response to induction chemotherapy and disease control in patients with advanced laryngeal carcinoma included in an organ preservation protocol

    Article • European Archives of Oto-Rhino-Laryngology, March 2017, Springer Science + Business Media

    Ms Cristina Valero, Dr Xavier León

  103. Human papillomavirus as prognostic marker with rising prevalence in neck squamous cell carcinoma of unknown primary: A retrospective multicentre study

    Article • European Journal of Cancer, March 2017, Elsevier

    Dr Xavier León

  104. Nasopharyngeal carcinoma: 30-year experience of a single institution in a non-endemic area

    Article • Revista de Oncología, January 2017, Springer Science + Business Media

    Dr Xavier León

  105. The role of HPV on the risk of second primary neoplasia in patients with oropharyngeal carcinoma

    Article • Oral Oncology, January 2017, Elsevier

    Dr Xavier León

  106. Nodules en cavité orale, pharynx et larynx

    Article • Annales françaises d Oto-rhino-laryngologie et de Pathologie Cervico-faciale, September 2016, Elsevier

    Dr Xavier León

  107. Oral cavity, pharynx and larynx nodules

    Article • European Annals of Otorhinolaryngology Head and Neck Diseases, September 2016, Elsevier

    Dr Xavier León

  108. Pretreatment count of peripheral neutrophils, monocytes, and lymphocytes as independent prognostic factor in patients with head and neck cancer

    Article • Head & Neck, August 2016, Wiley

    Ms Cristina Valero, Dr Xavier León

  109. Prognostic significance of extracapsular spread in isolated neck recurrences in head and neck squamous cell carcinoma patients

    Article • European Archives of Oto-Rhino-Laryngology, August 2016, Springer Science + Business Media

    Dr Xavier León

  110. uPA/uPAR and SERPINE1 in head and neck cancer: role in tumor resistance, metastasis, prognosis and therapy

    Article • Oncotarget, June 2016, Impact Journals, LLC

    Dr Xavier León

  111. Expression of the CXCL12/CXCR4 chemokine axis predicts regional control in head and neck squamous cell carcinoma

    Article • European Archives of Oto-Rhino-Laryngology, June 2016, Springer Science + Business Media

    Dr Xavier León

  112. Management of recurrent head and neck cancer: variables related to salvage surgery

    Article • European Archives of Oto-Rhino-Laryngology, May 2016, Springer Science + Business Media

    Dr Xavier León

  113. Expresión de Heat Shock Protein-90 (HSP-90) como factor predictor de la respuesta a radioterapia en pacientes con tumores de cabeza y cuello

    Article • Acta Otorrinolaringológica Española, May 2016, Elsevier

    Dr Xavier León

  114. Classification of parotidectomies: a proposal of the European Salivary Gland Society

    Article • European Archives of Oto-Rhino-Laryngology, February 2016, Springer Science + Business Media

    Professor Pavel Dulguerov, Professor Orlando Guntinas-Lichius, Dr Xavier León

  115. HPV Involvement in Head and Neck Cancers: Comprehensive Assessment of Biomarkers in 3680 Patients

    Article • JNCI Journal of the National Cancer Institute, January 2016, Oxford University Press (OUP)

    Dr Xavier León

  116. External validation of sTWEAK as a prognostic noninvasive biomarker for head and neck squamous cell carcinoma

    Article • Head & Neck, December 2015, Wiley

    Dr Xavier León

  117. CKMT1 and NCOA1 expression as a predictor of clinical outcome in patients with advanced-stage head and neck squamous cell carcinoma

    Article • Head & Neck, October 2015, Wiley

    Dr Xavier León

  118. Expression of IL-1α correlates with distant metastasis in patients with head and neck squamous cell carcinoma

    Article • Oncotarget, October 2015, Impact Journals, LLC

    Dr Xavier León

  119. Reconstrucción de defectos de cavidad oral con colgajos tipo FAMM (colgajo músculo-mucoso de arteria facial). Nuestra experiencia

    Article • Acta Otorrinolaringológica Española, September 2015, Elsevier

    Dr Xavier León

  120. Enhanced cell migration and apoptosis resistance may underlie the association between high SERPINE1 expression and poor outcome in head and neck carcinoma patients

    Article • Oncotarget, August 2015, Impact Journals, LLC

    Dr Xavier León

  121. Salvage surgery after local recurrence in patients with head and neck carcinoma treated with chemoradiotherapy or bioradiotherapy

    Article • Auris Nasus Larynx, April 2015, Elsevier

    Dr Xavier León

  122. Tratamiento quirúrgico de los carcinomas escamosos de cabeza y cuello en España durante el periodo 2006-2011

    Article • Acta Otorrinolaringológica Española, March 2015, Elsevier

    Dr Xavier León

  123. Management of Sinonasal Mucosal Melanomas and Comparison of Classification Staging Systems

    Article • American Journal of Rhinology and Allergy, January 2015, SAGE Publications

    Dr Xavier León

  124. Parotid Incidentaloma Identified by Positron Emission/Computed Tomography: When to Consider Diagnoses Other than Warthin Tumor

    Article • International Archives of Otorhinolaryngology, December 2014, Thieme Publishing Group

    Dr Xavier León

  125. Prostacyclin-synthase expression in head and neck carcinoma patients and its prognostic value in the response to radiotherapy

    Article • The Journal of Pathology, December 2014, Wiley

    Mercedes Camacho, Dr Xavier León

  126. Stomal recurrence in head and neck cancer patients with temporary tracheostomy

    Article • Auris Nasus Larynx, October 2014, Elsevier

    Dr Xavier León

  127. Reply to letter to the editor

    Article • Head & Neck, July 2014, Wiley

    Dr Xavier León

  128. Etiología y tratamiento de la parálisis laríngea: estudio retrospectivo de 108 pacientes

    Article • Acta Otorrinolaringológica Española, July 2014, Elsevier

    Dr Xavier León

  129. Low blood levels of sTWEAK are related to locoregional failure in head and neck cancer

    Article • European Archives of Oto-Rhino-Laryngology, May 2014, Springer Science + Business Media

    Dr Xavier León

  130. High RAB 25 expression is associated with good clinical outcome in patients with locally advanced head and neck squamous cell carcinoma

    Article • Cancer Medicine, October 2013, Wiley

    Dr Xavier León

  131. Elective treatment of the neck for second primary tumors of the head and neck

    Article • European Archives of Oto-Rhino-Laryngology, July 2013, Springer Science + Business Media

    Dr Xavier León

  132. Adherencia crónica al humidificador de traqueostoma en pacientes laringectomizados

    Article • Acta Otorrinolaringológica Española, July 2013, Elsevier

    Dr Xavier León

  133. Inclusion of Extracapsular Spread in the pTNM Classification System

    Article • JAMA Otolaryngology–Head & Neck Surgery, May 2013, American Medical Association (AMA)

    Dr Xavier León

  134. Prognostic role of MMP-9 expression in head and neck carcinoma patients treated with radiotherapy or chemoradiotherapy

    Article • Oral Oncology, April 2013, Elsevier

    Dr Xavier León

  135. Endonasal Endoscopic Scalpel-Forceps Dacryocystorhinostomy vs Endocanalicular Diode Laser Dacryocystorhinostomy

    Article • European Journal of Ophthalmology, January 2013, SAGE Publications

    Dr Xavier León

  136. Delayed carotid blow-out syndrome: a new complication of chemoradiotherapy treatment in pharyngolaryngeal carcinoma

    Article • The Journal of Laryngology & Otology, September 2012, Cambridge University Press

    Dr Xavier León

  137. Prognostic factors in head and neck squamous cell carcinoma: Comparison of CHAID decision trees technology and cox analysis

    Article • Head & Neck, June 2012, Wiley

    Dr Xavier León

  138. Gene expression signatures and molecular markers associated with clinical outcome in locally advanced head and neck carcinoma

    Article • Carcinogenesis, June 2012, Oxford University Press (OUP)

    Dr Xavier León

  139. Overexpression of the nuclear factor-kappa B (p65) in association with local failure in patients with head and neck carcinoma undergong radiotherapy or chemoradiotherapy

    Article • Head & Neck, March 2012, Wiley

    Dr Xavier León

  140. Comparison of Chi-Squared Automatic Interaction Detection Classification Trees vs TNM Classification for Patients With Head and Neck Squamous Cell Carcinoma

    Article • Archives of Otolaryngology - Head and Neck Surgery, March 2012, American Medical Association (AMA)

    Dr Xavier León

  141. Second, third, and fourth head and neck tumors. A progressive decrease in survival

    Article • Head & Neck, February 2012, Wiley

    Dr Xavier León

  142. Interaction between head and neck squamous cell carcinoma cells and fibroblasts in the biosynthesis of PGE2

    Article • Journal of Lipid Research, February 2012, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Xavier León

  143. Sarcomas de cabeza y cuello. Nuestra experiencia

    Article • Acta Otorrinolaringológica Española, November 2011, Elsevier

    Dr Xavier León

  144. Total or subtotal glossectomy with microsurgical reconstruction: Functional and oncological results

    Article • Microsurgery, September 2011, Wiley

    Dr Xavier León

  145. Tumor cells induce COX-2 and mPGES-1 expression in microvascular endothelial cells mainly by means of IL-1 receptor activation

    Article • Microvascular Research, May 2011, Elsevier

    Dr Xavier León

  146. Extended deep inferior epigastric artery perforator flap for head and neck reconstruction: A clinical experience with 100 patients

    Article • Head & Neck, November 2010, Wiley

    Dr Xavier León

  147. Salvage surgery after locoregional failure in head and neck carcinoma patients treated with chemoradiotherapy

    Article • European Archives of Oto-Rhino-Laryngology, August 2010, Springer Science + Business Media

    Dr Xavier León

  148. Risk of third and fourth tumors in patients with head and neck cancer

    Article • Head & Neck, February 2010, Wiley

    Dr Xavier León

  149. Management of Sinonasal Inverted Papillomas and Comparison of Classification Staging Systems

    Article • American Journal of Rhinology and Allergy, January 2010, SAGE Publications

    Dr Xavier León

  150. Parotidectomías en tumores benignos: clasificación «Sant Pau» de la extensión de la resección

    Article • Acta Otorrinolaringológica Española, January 2010, Elsevier

    Dr Xavier León

  151. Tratamiento endoscópico combinado vs. abierto en el divertículo de Zenker

    Article • Acta Otorrinolaringológica Española, November 2009, Elsevier

    Dr Xavier León

  152. Treatment results for ethmoid sinus carcinoma

    Article • The Journal of Laryngology & Otology, August 2009, Cambridge University Press

    Dr Xavier León

  153. Resultados de un protocolo de preservación de órgano en pacientes con tumores localmente avanzados de la laringe

    Article • Acta Otorrinolaringológica Española, June 2009, Elsevier

    Dr Xavier León

  154. Ceratocricoid muscle: An embryological and anatomical study

    Article • Clinical Anatomy, May 2009, Wiley

    Dr Xavier León

  155. Influence of the persistence of tobacco and alcohol use in the appearance of second neoplasm in patients with a head and neck cancer. A case–control study

    Article • Cancer Causes & Control, December 2008, Springer Science + Business Media

    Dr Xavier León

  156. Prostaglandin E2pathway in head and neck squamous cell carcinoma

    Article • Head & Neck, September 2008, Wiley

    Mercedes Camacho, Dr Xavier León

  157. Ku70 predicts response and primary tumor recurrence after therapy in locally advanced head and neck cancer

    Article • International Journal of Cancer, September 2008, Wiley

    Dr Xavier León

  158. Colgajo de pectoral mayor

    Article • Acta Otorrinolaringológica Española, July 2008, Elsevier

    Dr Xavier León

  159. Overview of the efficacy of cetuximab in recurrent and/or metastatic squamous cell carcinoma of the head and neck in patients who previously failed platinum-based therapies

    Article • Cancer, June 2008, Wiley

    Dr Xavier León

  160. Trasplante de la laringe: ¿una opción terapéutica para el siglo XXI? Revisión de la literatura

    Article • Acta Otorrinolaringológica Española, March 2008, Elsevier

    Dr Xavier León

  161. Potential Structures That Could Be Confused With a Nonrecurrent Inferior Laryngeal Nerve: An Anatomic Study

    Article • The Laryngoscope, January 2008, Wiley

    Dr Xavier León

  162. Recurrent laryngeal squamous cell carcinoma: rTNM versus composite laryngeal recurrence staging system. Proposal for a modification of the CLRSS to improve patient classification

    Article • Head & Neck, January 2008, Wiley

    Dr Xavier León

  163. Modalidades de preservación de órgano en carcinomas de laringe e hipofaringe

    Article • Acta Otorrinolaringológica Española, December 2007, Elsevier

    Dr Xavier León

  164. External validation of a risk group defined by recursive partitioning analysis in patients with head and neck carcinoma treated with surgery and postoperative radiotherapy

    Article • Head & Neck, September 2007, Wiley

    Dr Xavier León

  165. Supracricoid laryngectomy as salvage surgery after failure of radiation therapy

    Article • European Archives of Oto-Rhino-Laryngology, February 2007, Springer Science + Business Media

    Dr Xavier León

  166. Organ Preservation in Laryngeal and Hypopharyngeal Cancer

    Article • Acta Otorrinolaringologica (English Edition), January 2007, Elsevier

    Dr Xavier León

  167. A Retrospective Analysis of the Outcome of Patients with Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck Refractory to a Platinum-based Chemotherapy

    Article • Clinical Oncology, September 2005, Elsevier

    Dr Xavier León

  168. Metachronous second primary tumours in the aerodigestive tract in patients with early stage head and neck squamous cell carcinomas

    Article • European Archives of Oto-Rhino-Laryngology, May 2005, Springer Science + Business Media

    Dr Xavier León

  169. Comparison of the Radiation Therapy Oncology Group recursive partitioning classification and Union Internationale Contre le Cancer TNM classification for patients with head and neck carcinoma

    Article • Head & Neck, March 2005, Wiley

    Dr Xavier León

  170. Incidence and Significance of Clinically Unsuspected Thyroid Tissue in Lymph Nodes Found During Neck Dissection in Head and Neck Carcinoma Patients

    Article • The Laryngoscope, March 2005, Wiley

    Dr Xavier León

  171. Variability in Nerve Patterns of the Adductor Muscle Group Supplied by the Recurrent Laryngeal Nerve

    Article • The Laryngoscope, February 2005, Wiley

    Dr Xavier León

  172. Laryngeal cancer in non-smoking and non-drinking patients

    Article • Acta Oto-Laryngologica, August 2004, Taylor & Francis

    Dr Xavier León

  173. Is dissection of level V necessary in patients with T2–T4N0 supraglottic cancer?

    Article • The Journal of Laryngology & Otology, March 2004, Cambridge University Press

    Dr Xavier León

  174. Results of an organ preservation protocol with induction chemotherapy and radiotherapy in patients with locally advanced laryngeal carcinoma

    Article • European Archives of Oto-Rhino-Laryngology, February 2004, Springer Science + Business Media

    Dr Xavier León

  175. Variability of the Nerve Supply Patterns of the Human Posterior Cricoarytenoid Muscle

    Article • The Laryngoscope, April 2003, Wiley

    Dr Xavier León

  176. Is the External Laryngeal Nerve an Exclusively Motor Nerve? The Cricothyroid Connection Branch

    Article • The Laryngoscope, March 2003, Wiley

    Dr Xavier León

  177. The effect of waiting time on local control and survival in head and neck carcinoma patients treated with radiotherapy

    Article • Radiotherapy and Oncology, March 2003, Elsevier

    Dr Xavier León

  178. Second Primary Tumors in Head and Neck Cancer Patients

    Article • Acta Oto-Laryngologica, October 2002, Taylor & Francis

    Dr Xavier León, Professor Patrick James Bradley

  179. Results of salvage surgery for local or regional recurrence after larynx preservation with induction chemotherapy and radiotherapy

    Article • Head & Neck, August 2001, Wiley

    Dr Xavier León

  180. Selective dissection of levels II-III with intraoperative control of the upper and middle jugular nodes: A therapeutic option for the no neck

    Article • Head & Neck, May 2001, Wiley

    Dr Xavier León

  181. An anatomical study of anastomoses between the laryngeal nerves

    Article • The Laryngoscope, June 1999, Wiley

    Dr Xavier León

  182. Foramen Thyroideum: A Comparative Study in Embryos, Fetuses, and Adults

    Article • The Laryngoscope, August 1997, Wiley

    Dr Xavier León