All Stories

  1. Global Analysis of Human Nonreceptor Tyrosine Kinase Specificity Using High-Density Peptide Microarrays

    Article • Journal of Proteome Research, August 2014, American Chemical Society (ACS)

    Dr Vesa P Hytönen, Dr Heung-Chin Cheng

  2. pH-Dependent Deformations of the Energy Landscape of Avidin-like Proteins Investigated by Single Molecule Force Spectroscopy

    Article • Molecules, August 2014, MDPI AG

    Dr Vesa P Hytönen

  3. Cationic polymer brush-modified cellulose nanocrystals for high-affinity virus binding

    Article • Nanoscale, August 2014, Royal Society of Chemistry

    Dr Vesa P Hytönen

  4. Molecular engineering of avidin and hydrophobin for functional self-assembling interfaces

    Article • Colloids and Surfaces B Biointerfaces, August 2014, Elsevier

    Dr Vesa P Hytönen

  5. Chimeric Avidin – NMR Structure and Dynamics of a 56 kDa Homotetrameric Thermostable Protein

    Article • PLoS ONE, June 2014, PLOS

    Dr Vesa P Hytönen

  6. Positive association between biotin and the abundance of root-feeding nematodes

    Article • Soil Biology and Biochemistry, June 2014, Elsevier

    Dr Vesa P Hytönen

  7. Enhancement of adhesion and promotion of osteogenic differentiation of human adipose stem cells by poled electroactive poly(vinylidene fluoride)

    Article • Journal of Biomedical Materials Research Part A, May 2014, Wiley

    Dr Vesa P Hytönen, Dr Vitor Sencadas, Professor Senentxu Lanceros-Mendez

  8. Coxsackievirus B3 VLPs purified by ion exchange chromatography elicit strong immune responses in mice

    Article • Antiviral Research, April 2014, Elsevier

    Dr Vesa P Hytönen

  9. A Novel Chimeric Avidin with Increased Thermal Stability Using DNA Shuffling

    Article • PLoS ONE, March 2014, PLOS

    Dr Vesa P Hytönen

  10. Investigating the binding behaviour of two avidin‐based testosterone binders using molecular recognition force spectroscopy

    Article • Journal of Molecular Recognition, January 2014, Wiley

    Dr Vesa P Hytönen

  11. Protein conformation as a regulator of cell–matrix adhesion

    Article • Physical Chemistry Chemical Physics, January 2014, Royal Society of Chemistry

    Dr Vesa P Hytönen

  12. The talin–integrin interface under mechanical stress

    Article • Molecular BioSystems, January 2014, Royal Society of Chemistry

    Dr Vesa P Hytönen

  13. Beta carbonic anhydrases: novel targets for pesticides and anti-parasitic agents in agriculture and livestock husbandry

    Article • Parasites & Vectors, January 2014, Springer Science + Business Media

    Dr Vesa P Hytönen, Dr Reza Zolfaghari Emameh

  14. Kinetics of bioconjugate nanoparticle label binding in a sandwich-type immunoassay

    Article • Analytical and Bioanalytical Chemistry, November 2013, Springer Science + Business Media

    Dr Vesa P Hytönen

  15. Zebavidin

    Article • November 2013, Protein Data Bank, Rutgers University

    Dr Vesa P Hytönen

  16. Crystal structure of core-bradavidin

    Article • October 2013, Protein Data Bank, Rutgers University

    Dr Vesa P Hytönen

  17. Crystal structure of an avidin mutant

    Article • October 2013, Protein Data Bank, Rutgers University

    Dr Vesa P Hytönen

  18. Reversible Biofunctionalization of Surfaces with a Switchable Mutant of Avidin

    Article • Bioconjugate Chemistry, September 2013, American Chemical Society (ACS)

    Dr Vesa P Hytönen

  19. The highly dynamic oligomeric structure of bradavidin II is unique among avidin proteins

    Article • Protein Science, June 2013, Wiley

    Dr Vesa P Hytönen

  20. GFP's Mechanical Intermediate States

    Article • PLoS ONE, October 2012, PLOS

    Dr Vesa P Hytönen

  21. Cysteine-tagged chimeric avidin forms high binding capacity layers directly on gold

    Article • Sensors and Actuators B Chemical, August 2012, Elsevier

    Dr Vesa P Hytönen

  22. Structural and Functional Characteristics of Chimeric Avidins Physically Adsorbed onto Functionalized Polythiophene Thin Films

    Article • ACS Applied Materials & Interfaces, July 2012, American Chemical Society (ACS)

    Dr Vesa P Hytönen

  23. Peptide-functionalized chitosan–DNA nanoparticles for cellular targeting

    Article • Carbohydrate Polymers, July 2012, Elsevier

    Dr Vesa P Hytönen

  24. Protein–Protein Interactions: Inhibition of Mammalian Carbonic Anhydrases I–XV by the Murine Inhibitor of Carbonic Anhydrase and Other Members of the Transferrin Family

    Article • Journal of Medicinal Chemistry, May 2012, American Chemical Society (ACS)

    Dr Vesa P Hytönen

  25. Structure of Bradavidin – C-Terminal Residues Act as Intrinsic Ligands

    Article • PLoS ONE, May 2012, PLOS

    Dr Vesa P Hytönen

  26. Purification of norovirus-like particles (VLPs) by ion exchange chromatography

    Article • Journal of Virological Methods, April 2012, Elsevier

    Dr Sarah Jane Butcher, Dr Vesa P Hytönen

  27. Resonance assignments of the 56 kDa chimeric avidin in the biotin-bound and free forms

    Article • Biomolecular NMR Assignments, March 2012, Springer Science + Business Media

    Dr Vesa P Hytönen

  28. Production and characterization of virus-like particles and the P domain protein of GII.4 norovirus

    Article • Journal of Virological Methods, January 2012, Elsevier

    Dr Sarah Jane Butcher, Dr Vesa P Hytönen

  29. Printable and flexible macroporous organosilica film with high protein adsorption capacity

    Article • Thin Solid Films, January 2012, Elsevier

    Dr Vesa P Hytönen

  30. DNA family shuffling within the chicken avidin protein family – A shortcut to more powerful protein tools

    Article • Journal of Biotechnology, January 2012, Elsevier

    Dr Vesa P Hytönen

  31. A comparison of immunogenicity of norovirus GII‐4 virus‐like particles and P‐particles

    Article • Immunology, December 2011, Wiley

    Dr Vesa P Hytönen

  32. Identification of proprotein convertase substrates using genome-wide expression correlation analysis

    Article • BMC Genomics, December 2011, Springer Science + Business Media

    Dr Vesa P Hytönen

  33. Versatile bio-ink for covalent immobilization of chimeric avidin on sol–gel substrates

    Article • Colloids and Surfaces B Biointerfaces, October 2011, Elsevier

    Dr Vesa P Hytönen

  34. Acetaldehyde-derived modifications on cytosolic human carbonic anhydrases

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, June 2011, Taylor & Francis

    Dr Vesa P Hytönen

  35. Modification of the loops in the ligand-binding site turns avidin into a steroid-binding protein

    Article • BMC Biotechnology, June 2011, Springer Science + Business Media

    Dr Vesa P Hytönen

  36. Construction of Chimeric Dual-Chain Avidin by Tandem Fusion of the Related Avidins

    Article • PLoS ONE, May 2011, PLOS

    Dr Vesa P Hytönen

  37. Defined-size DNA triple crossover construct for molecular electronics: modification, positioning and conductance properties

    Article • Nanotechnology, May 2011, Institute of Physics Publishing

    Dr Vesa P Hytönen

  38. Bifunctional Avidin with Covalently Modifiable Ligand Binding Site

    Article • PLoS ONE, January 2011, PLOS

    Dr Vesa P Hytönen

  39. Growth of immobilized DNA by polymerase: bridging nanoelectrodes with individual dsDNA molecules

    Article • Nanoscale, January 2011, Royal Society of Chemistry

    Dr Vesa P Hytönen

  40. Chimeric avidin shows stability against harsh chemical conditions—biochemical analysis and 3D structure

    Article • Biotechnology and Bioengineering, November 2010, Wiley

    Dr Vesa P Hytönen

  41. Analysis of a shortened form of human carbonic anhydrase VII expressed in vitro compared to the full-length enzyme

    Article • Biochimie, August 2010, Elsevier

    Dr Vesa P Hytönen

  42. Characterization of the first beta-class carbonic anhydrase from an arthropod (Drosophila melanogaster) and phylogenetic analysis of beta-class carbonic anhydrases in invertebrates

    Article • BMC Biochemistry, January 2010, Springer Science + Business Media

    Dr Vesa P Hytönen

  43. Translating Mechanical Force into Discrete Biochemical Signal Changes

    Article • November 2009, Cambridge University Press

    Dr Vesa P Hytönen

  44. Structural and functional characteristics of xenavidin, the first frog avidin from Xenopus tropicalis

    Article • BMC Structural Biology, September 2009, Springer Science + Business Media

    Dr Vesa P Hytönen

  45. Crystal Structure of Rhizavidin: Insights into the Enigmatic High-Affinity Interaction of an Innate Biotin-Binding Protein Dimer

    Article • Journal of Molecular Biology, February 2009, Elsevier

    Dr Vesa P Hytönen

  46. Bradavidin II from Bradyrhizobium japonicum: A new avidin-like biotin-binding protein

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, July 2008, Elsevier

    Dr Vesa P Hytönen

  47. Rational Modification of Ligand‐Binding Preference of Avidin by Circular Permutation and Mutagenesis

    Article • ChemBioChem, May 2008, Wiley

    Dr Vesa P Hytönen

  48. Rational Modification of Ligand‐Binding Preference of Avidin by Circular Permutation and Mutagenesis

    Article • ChemBioChem, April 2008, Wiley

    Dr Vesa P Hytönen

  49. Critical importance of loop conformation to avidin-enhanced hydrolysis of an active biotin ester

    Article • Acta Crystallographica Section D Biological Crystallography, February 2008, International Union of Crystallography

    Dr Vesa P Hytönen

  50. How Force Might Activate Talin's Vinculin Binding Sites: SMD Reveals a Structural Mechanism

    Article • PLoS Computational Biology, February 2008, PLOS

    Dr Vesa P Hytönen

  51. Trapping of 27 bp–8 kbp DNA and immobilization of thiol-modified DNA using dielectrophoresis

    Article • Nanotechnology, June 2007, Institute of Physics Publishing

    Dr Vesa P Hytönen

  52. Brave new (strept)avidins in biotechnology

    Article • Trends in Biotechnology, June 2007, Elsevier

    Dr Vesa P Hytönen

  53. Structure and characterization of a novel chicken biotin-binding protein A (BBP-A)

    Article • BMC Structural Biology, March 2007, Springer Science + Business Media

    Dr Vesa P Hytönen

  54. Binding Properties of HABA-Type Azo Derivatives to Avidin and Avidin-Related Protein 4

    Article • Chemistry & Biology, October 2006, Elsevier

    Dr Vesa P Hytönen

  55. Carbon Nanotubes as Electrodes for Dielectrophoresis of DNA

    Article • Nano Letters, June 2006, American Chemical Society (ACS)

    Dr Vesa P Hytönen

  56. Controlling Quaternary Structure Assembly: Subunit Interface Engineering and Crystal Structure of Dual Chain Avidin

    Article • Journal of Molecular Biology, June 2006, Elsevier

    Dr Vesa P Hytönen

  57. Factors Dictating the Pseudocatalytic Efficiency of Avidins

    Article • Journal of Molecular Biology, May 2006, Elsevier

    Dr Vesa P Hytönen

  58. 188. Internalization of Novel Delivery Vector TAT-Streptavidin into Human Cells

    Article • Molecular Therapy, January 2006, Elsevier

    Dr Vesa P Hytönen

  59. Tetravalent single-chain avidin: from subunits to protein domains via circularly permuted avidins

    Article • Biochemical Journal, December 2005, Portland Press Ltd.

    Dr Vesa P Hytönen

  60. Dual‐affinity avidin molecules

    Article • Proteins Structure Function and Bioinformatics, September 2005, Wiley

    Dr Vesa P Hytönen

  61. High-resolution crystal structure of an avidin-related protein: insight into high-affinity biotin binding and protein stability

    Article • Acta Crystallographica Section D Biological Crystallography, April 2005, International Union of Crystallography

    Dr Vesa P Hytönen

  62. Design and Construction of Highly Stable, Protease-resistant Chimeric Avidins

    Article • Journal of Biological Chemistry, January 2005, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vesa P Hytönen

  63. How force might activate talin's vinculin binding sites: SMD reveals a structural mechanism

    Article • PLoS Computational Biology, January 2005, PLOS

    Dr Vesa P Hytönen

  64. Efficient production of active chicken avidin using a bacterial signal peptide inEscherichia coli

    Article • Biochemical Journal, December 2004, Portland Press Ltd.

    Dr Vesa P Hytönen, Dr Seppo Yla-Herttuala

  65. Introduction of histidine residues into avidin subunit interfaces allows pH‐dependent regulation of quaternary structure and biotin binding

    Article • FEBS Letters, November 2003, Wiley

    Dr Vesa P Hytönen

  66. Chicken avidin-related proteins show altered biotin-binding and physico-chemical properties as compared with avidin

    Article • Biochemical Journal, May 2002, Portland Press Ltd.

    Dr Vesa P Hytönen