All Stories

  1. Magnesium Ion-Driven Folding and Conformational Switching Kinetics of Tetracycline Binding Aptamer: Implications for in vivo Riboswitch Engineering
  2. A Hairpin Ribozyme Derived Spliceozyme
  3. Boronic Acid Assisted Self‐Assembly of Functional RNAs
  4. Reinforcement of the Tumor Suppressing Properties of microRNA-1 by Substitution at the C2′ Position of Varying Ribose Residues in Chemically Synthesized microRNA-1 Molecules
  5. CAG-Repeat RNA Hairpin Folding and Recruitment to Nuclear Speckles with a Pivotal Role of ATP as a Cosolute
  6. Azide‐Modified Nucleosides as Versatile Tools for Bioorthogonal Labeling and Functionalization
  7. Design and NMR characterization of reversible head-to-tail boronate-linked macrocyclic nucleic acids
  8. Vesicle encapsulation stabilizes intermolecular association and structure formation of functional RNA and DNA
  9. RNA self-splicing by engineered hairpin ribozyme variants
  10. Azido Functionalized Nucleosides Linked to Controlled Pore Glass as Suitable Starting Materials for Oligonucleotide Synthesis by the Phosphoramidite Approach
  11. Tumor-Specific Delivery of 5-Fluorouracil–Incorporated Epidermal Growth Factor Receptor–Targeted Aptamers as an Efficient Treatment in Pancreatic Ductal Adenocarcinoma Models
  12. Towards Higher Complexity in the RNA World: Hairpin Ribozyme Supported RNA Recombination
  13. Self-cleaving ribozymes: substrate specificity and synthetic biology applications
  14. Synthesis of fully protected trinucleotide building blocks on a disulphide-linked soluble support
  15. Boronic Acid‐Mediated Activity Control of Split 10–23 DNAzymes
  16. Changed reactivity of secondary hydroxy groups in C8-modified adenosine – lessons learned from silylation
  17. Reductive Charge Transfer through an RNA Aptamer
  18. Reductive Charge Transfer through an RNA Aptamer
  19. Changed reactivity of secondary hydroxyl groups in C8-modified adenosine – lessons learned from silylation
  20. Selective Chemical Modification of DNA with Boronic Acids by On-Column CuAAc Reactions
  21. Recent advances in understanding circular RNAs
  22. Splitting aptamers and nucleic acid enzymes for the development of advanced biosensors
  23. A mouse model for intellectual disability caused by mutations in the X-linked 2′‑O‑methyltransferase Ftsj1 gene
  24. Solid Phase Assembly of Fully Protected Trinucleotide Building Blocks for Codon-Based Gene Synthesis
  25. Engineering of hairpin ribozyme variants for RNA recombination and splicing
  26. Synthesis of Trinucleotide Building Blocks in Solution and on Solid Phase
  27. Preparation of trinucleotide phosphoramidites as synthons for the synthesis of gene libraries
  28. Ligand‐Induced Dimerization of a Truncated Parallel MYC G‐Quadruplex
  29. Preparation and characterization of pyrene modified uridine derivatives as potential electron donors in RNA
  30. RNA-based boronate internucleosidic linkages: an entry into reversible templated ligation and loop formation
  31. Synthesis and Engineering of Circular RNAs
  32. Phosphorous chemistry in vivo: what makes the phosphoesters in DNA and RNA so diverse?
  33. Special Issue: Ribozymes and RNA Catalysis
  34. Challenges and Perspectives in Nucleic Acid Enzyme Engineering
  35. Sugar-Edge Interactions in a DNA-RNA G-Quadruplex: Evidence of Sequential C−H⋅⋅⋅O Hydrogen Bonds Contributing to RNA Quadruplex Folding
  36. Zuckerseitige Wechselwirkungen in einem DNA-RNA-G-Quadruplex: Hinweise auf sequentielle C−H⋅⋅⋅O-Wasserstoffbrücken als Beitrag zur RNA-Quadruplex-Faltung
  37. Review - Ribozymes and Nucleic Acid Catalysis
  38. Challenges and Opportunities in the Development of Aptamers for TNFα
  39. RNA Hairpin Folding in the Crowded Cell
  40. In vitro repair of a defective EGFP transcript and translation into a functional protein
  41. Hairpin ribozyme mediated RNA recombination
  42. Landmarks in the Evolution of (t)-RNAs from the Origin of Life up to Their Present Role in Human Cognition
  43. Sequence-controlled RNA self-processing: computational design, biochemical analysis, and visualization by AFM
  44. Faculty of 1000 evaluation for NAD captureSeq indicates NAD as a bacterial cap for a subset of regulatory RNAs.
  45. Engineering of ribozymes with useful activities in the ancient RNA world
  46. Nucleic Acids
  47. RNA circularization strategies in vivo and in vitro
  48. Ribozymes that can be regulated by external stimuli
  49. Faculty of 1000 evaluation for The selective tRNA aminoacylation mechanism based on a single G•U pair.
  50. Synthesis of a bifunctional cytidine derivative and its conjugation to RNA for in vitro selection of a cytidine deaminase ribozyme
  51. Design and Characterization of a Twin Ribozyme for Potential Repair of a Deletion Mutation within the OncogenicCTNNB1-ΔS45 mRNA
  52. Faculty of 1000 evaluation for A semi-synthetic organism with an expanded genetic alphabet.
  53. RNA Aminoacylation Mediated by Sequential Action of Two Ribozymes and a Nonactivated Amino Acid
  54. RNA Ligation
  55. Faculty of 1000 evaluation for Architecture of the large subunit of the mammalian mitochondrial ribosome.
  56. Preparation of modified long-mer RNAs and analysis of FMN binding to theypaAaptamer fromB. subtilis
  57. Faculty of 1000 evaluation for A ribozyme that triphosphorylates RNA 5'-hydroxyl groups.
  58. Generation and selection of ribozyme variants with potential application in protein engineering and synthetic biology
  59. Synthesis of Site-Specifically Modified Long-mer RNAs
  60. Faculty of 1000 evaluation for Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo.
  61. Faculty of 1000 evaluation for Nanoplasmonic imaging of latent fingerprints and identification of cocaine.
  62. Faculty of 1000 evaluation for Tetrahydrobiopterin biosynthesis as an off-target of sulfa drugs.
  63. Faculty of 1000 evaluation for Circular RNAs are a large class of animal RNAs with regulatory potency.
  64. Complex formation with nucleic acids and aptamers alters the antigenic properties of platelet factor 4
  65. RNA self-processing: Formation of cyclic species and concatemers from a small engineered RNA
  66. Faculty of 1000 evaluation for Single-molecule detection of 5-hydroxymethylcytosine in DNA through chemical modification and nanopore analysis.
  67. Faculty of 1000 evaluation for An acetylene-bridged 6,8-purine dimer as a fluorescent switch-on probe for parallel g-quadruplexes.
  68. Faculty of 1000 evaluation for Visualization of Latent Fingermarks Using an Aptamer-Based Reagent.
  69. 2′-modified oligoribonucleotides containing 1,2-diol and aldehyde groups. Synthesis and properties
  70. RNA self-ligation: From oligonucleotides to full length ribozymes
  71. Faculty of 1000 evaluation for Widespread genetic switches and toxicity resistance proteins for fluoride.
  72. Faculty of 1000 evaluation for Small-molecule-induced DNA damage identifies alternative DNA structures in human genes.
  73. Faculty of 1000 evaluation for Direct fluorescence monitoring of DNA base excision repair.
  74. Mixed oligonucleotides for random mutagenesis: best way of making them
  75. A new and convenient approach for the preparation of β-cyanoethyl protected trinucleotide phosphoramidites
  76. Kinetic Characterization of Hairpin Ribozyme Variants
  77. The many faces of the hairpin ribozyme: Structural and functional variants of a small catalytic rna
  78. Faculty of 1000 evaluation for Cell-like systems with riboswitch controlled gene expression.
  79. Faculty of 1000 evaluation for Organization of intracellular reactions with rationally designed RNA assemblies.
  80. Faculty of 1000 evaluation for Ribozyme-catalyzed transcription of an active ribozyme.
  81. Faculty of 1000 evaluation for An isothermal system that couples ligand-dependent catalysis to ligand-independent exponential amplification.
  82. Faculty of 1000 evaluation for Real-time tRNA transit on single translating ribosomes at codon resolution.
  83. Accurate Distance Determination of Nucleic Acids via Förster Resonance Energy Transfer: Implications of Dye Linker Length and Rigidity
  84. Accurate Single-Molecule FRET Studies of Nucleic Acids Using Multi-Parameter Fluorescence Detection
  85. Synthesis of Specifically Modified Oligonucleotides for Application in Structural and Functional Analysis of RNA
  86. Design of hairpin ribozyme variants with improved activity for poorly processed substrates
  87. Impedimetric Detection of Hairpin Ribozyme Activity
  88. Faculty of 1000 evaluation for Combinatorial mutation interference analysis reveals functional nucleotides required for DNA catalysis.
  89. Potential of Aptamers as Artificial Receptors in Chemical Sensors
  90. Ligand-induced conformational capture of a synthetic tetracycline riboswitch revealed by pulse EPR
  91. Faculty of 1000 evaluation for New strategy for the synthesis of chemically modified RNA constructs exemplified by hairpin and hammerhead ribozymes.
  92. Faculty of 1000 evaluation for Stoichiometry and architecture of active DNA replication machinery in Escherichia coli.
  93. Faculty of 1000 evaluation for Reengineering orthogonally selective riboswitches.
  94. Faculty of 1000 evaluation for 19F NMR spectroscopy for the analysis of RNA secondary structure populations.
  95. Einzelmolekülsequenzierung von RNA
  96. Faculty of 1000 evaluation for Lack of evolvability in self-sustaining autocatalytic networks constraints metabolism-first scenarios for the origin of life.
  97. Reading the Code of Single RNA Molecules
  98. Faculty of 1000 evaluation for Crystal structure of the catalytic core of an RNA-polymerase ribozyme.
  99. Faculty of 1000 evaluation for Direct RNA sequencing.
  100. Faculty of 1000 evaluation for Rapid and simple ribozymic aminoacylation using three conserved nucleotides.
  101. Faculty of 1000 evaluation for Synthesis of activated pyrimidine ribonucleotides in prebiotically plausible conditions.
  102. Faculty of 1000 evaluation for One RNA plays three roles to provide catalytic activity to a group I intron lacking an endogenous internal guide sequence.
  103. Faculty of 1000 evaluation for Autocatalytic aptazymes enable ligand-dependent exponential amplification of RNA.
  104. Nucleic Acids from A to Z: A Concise Encyclopedia. Edited by Sabine Müller.
  105. Faculty of 1000 evaluation for TokenRNA: a new type of sequence-specific, label-free fluorescent biosensor for folded RNA molecules.
  106. Faculty of 1000 evaluation for A discontinuous hammerhead ribozyme embedded in a mammalian messenger RNA.
  107. Faculty of 1000 evaluation for Following translation by single ribosomes one codon at a time.
  108. Electrochemically Induced Modulation of the Catalytic Activity of a Reversible Redoxsensitive Riboswitch
  109. Faculty of 1000 evaluation for Click-click-click: single to triple modification of DNA.
  110. Quadruplex Nucleic Acids. Herausgegeben von Stephen Neidle und Shankar Balasubramanian.
  111. Quadruplex Nucleic Acids. Edited by Stephen Neidle and Shankar Balasubramanian.
  112. Faculty of 1000 evaluation for DNA-catalyzed formation of nucleopeptide linkages.
  113. Faculty of 1000 evaluation for Construction of DNA architectures with RNA hairpins.
  114. Synthesis of guanosine 5′-conjugates and their use as initiator molecules for transcription priming
  115. Faculty of 1000 evaluation for Structure and mechanism of a metal-sensing regulatory RNA.
  116. Twin ribozyme mediated removal of nucleotides from an internal RNA site
  117. Faculty of 1000 evaluation for Simultaneous nucleotide activation and synthesis of amino acid amides by a potentially prebiotic multi-component reaction.
  118. Faculty of 1000 evaluation for RNA maps reveal new RNA classes and a possible function for pervasive transcription.
  119. Faculty of 1000 evaluation for Selection and evolution of enzymes from a partially randomized non-catalytic scaffold.
  120. Drugs Made of RNA: Development and Application of Engineered RNAs for Gene Therapy
  121. Faculty of 1000 evaluation for Host immune system gene targeting by a viral miRNA.
  122. Faculty of 1000 evaluation for An RNA G-quadruplex in the 5' UTR of the NRAS proto-oncogene modulates translation.
  123. Faculty of 1000 evaluation for Protein composition of catalytically active human telomerase from immortal cells.
  124. Faculty of 1000 evaluation for CPD damage recognition by transcribing RNA polymerase II.
  125. Faculty of 1000 evaluation for Synthesis-mediated release of a small RNA inhibitor of RNA polymerase.
  126. Faculty of 1000 evaluation for Emergence of the universal genetic code imprinted in an RNA record.
  127. Methods in Molecular Biology, Vol. 335: Fluorescent Energy Transfer Nucleic Acid Probes: Designs and Protocols. Edited by Vladimir V. Didenko.
  128. RNA self-processing towards changed topology and sequence oligomerization
  129. Faculty of 1000 evaluation for Complete crystallographic analysis of the dynamics of CCA sequence addition.
  130. The Methanothermobacter thermautotrophicus ExoIII homologue Mth212 is a DNA uridine endonuclease
  131. Faculty of 1000 evaluation for Tertiary contacts distant from the active site prime a ribozyme for catalysis.
  132. Faculty of 1000 evaluation for Thermodynamic control of asymmetric amplification in amino acid catalysis.
  133. Lipidverankerte Oligonucleotide zur Bildung stabiler Doppelhelices in Membrandomänen
  134. Lipid-Anchored Oligonucleotides for Stable Double-Helix Formation in Distinct Membrane Domains
  135. Faculty of 1000 evaluation for Oligonucleotide-modified gold nanoparticles for intracellular gene regulation.
  136. Faculty of 1000 evaluation for Aptamer to ribozyme: the intrinsic catalytic potential of a small RNA.
  137. Faculty of 1000 evaluation for Folding DNA to create nanoscale shapes and patterns.
  138. Redoxaktive RNA-Schalter: allosterische Regulation von Ribozymaktivität durch Steuerung der Ligandengeometrie
  139. Redox-Active Riboswitching: Allosteric Regulation of Ribozyme Activity by Ligand-Shape Control
  140. Sensors made of RNA: tailored ribozymes for detection of small organic molecules, metals, nucleic acids and proteins
  141. Site-Specific Fluorescent and Affinity Labelling of RNA by Using a Small Engineered Twin Ribozyme
  142. Efficient RNA ligation by reverse-joined hairpin ribozymes and engineering of twin ribozymes consisting of conventional and reverse-joined hairpin ribozyme units
  143. Twin Ribozymes
  144. Chemische Biologie, biologische Chemie, bioorganische Chemie, Biochemie?: Chemical Biology. Von Herbert Waldmann, Petra Janning. Wiley-VCH, Weinheim, 2004. 247Seiten, brosch. 24,90 Euro. ISBN 3-527-30778-8
  145. Chemical synthesis of an artificially branched hairpin ribozyme variant with RNA cleavage activity
  146. RNA Synthesis by T7 RNA Polymerase Supported Primer Extension
  147. Stereoselective Synthesis oftrans-threo-trans-Oligopyrrolidines: Potential Agents for RNA Cleavage
  148. Current Strategies for the Synthesis of RNA
  149. The Preparation of DNA Duplexes Containing Internucleotide Phosphorothioate Groups in Various Positions of the Recognition Site for the EcoRII Restriction Endonuclease
  150. Engineered Ribozymes as Molecular Tools for Site-Specific Alteration of RNA Sequence
  151. Another Face of RNA: Metabolite-Induced “Riboswitching” for Regulation of Gene Expression
  152. Gezielte RNA-Sequenz-Veränderung durch ein synthetisches Twinribozym
  153. Site-Directed Alteration of RNA Sequence Mediated by an Engineered Twin Ribozyme
  154. External Regulation of Hairpin Ribozyme Activity by an Oligonucleotide Effector
  155. 5-(Benzylmercapto)-1H-tetrazole as activator for 2′-O-TBDMS phosphoramidite building blocks in RNA synthesis
  156. Buchbesprechung: Chemistry for the 21st Century. Herausgegeben von Ehud Keinan und Israel Schechter
  157. Buchbesprechung: Chemistry for the 21st Century. Herausgegeben von Ehud Keinan und Israel Schechter
  158. Book Review: Chemistry for the 21st Century. Edited by Ehud Keinan and Israel Schechter
  159. Spermine Supports Catalysis of Hairpin Ribozyme Variants to Differing Extents
  160. RNA double cleavage by a hairpin-derived twin ribozyme
  161. Inter-domain cross-linking and molecular modelling of the hairpin ribozyme
  162. Base and Sugar Requirements for RNA Cleavage of Essential Nucleoside Residues in Internal Loop B of the Hairpin Ribozyme: Implications for Secondary Structure
  163. A New Approach to the Synthesis of 2-Aminopurine-2′-deoxyribosideviaTri-n-butyltin Hydride Reduction
  164. The interaction of DNA duplexes containing 2-aminopurine with restrictionendonucleases EcoRllandSsoll
  165. Sequence-specific and mechanism-based crosslinking of Dcm DNA cytosine-C5methyltransferase ofE.coliK-12 to synthetic oligonucleotides containing 5-fluoro-2'-deoxycytidine
  166. The use of oligonucleotide probes containing 2′-deoxy-2′-fluoronucleosides for regiospecific cleavage of RNA by RNase H from Escherichia coli
  167. Chemical synthesis of 2′-deoxyoligonucleotides containing 5-fluoro-2′-deoxycytidine
  168. Fast Quantitative Assay of Sequence-Specific Endonuclease Activity Based on DNA Sequencer Technology
  169. Transformation von Uridin- zu Cytidinderivaten durch selektive Aminierung