All Stories

  1. Cardiomyocyte maturation alters molecular stress response capacities and determines cell survival upon mitochondrial dysfunction

    Article • Free Radical Biology and Medicine, March 2024, Elsevier

    Dr Jörg-Detlef Drenckhahn

  2. Cardiomyocyte hyperplasia and immaturity but not hypertrophy are characteristic features of patients with RASopathies

    Article • Journal of Molecular and Cellular Cardiology, March 2023, Elsevier

    Dr Jörg-Detlef Drenckhahn

  3. Inhibition of mitochondrial respiration has fundamentally different effects on proliferation, cell survival and stress response in immature versus differentiated cardiomyocyte cell lines

    Article • Frontiers in Cell and Developmental Biology, September 2022, Frontiers

    Dr Jörg-Detlef Drenckhahn

  4. Dietary protein restriction throughout intrauterine and postnatal life results in potentially beneficial myocardial tissue remodeling in the adult mouse heart

    Article • Scientific Reports, October 2019, Springer Science + Business Media

    Dr Jörg-Detlef Drenckhahn

  5. Impact of Intrauterine Growth Restriction on the Capillarisation of the Early Postnatal Rat Heart

    Article • The Anatomical Record, November 2018, Wiley

    Dr Jörg-Detlef Drenckhahn

  6. P448Dietary protein restriction throughout intrauterine development and postnatal life alters myocardial tissue composition but not left ventricular function in the adult mouse heart

    Article • Cardiovascular Research, April 2018, Oxford University Press (OUP)

    Dr Jörg-Detlef Drenckhahn

  7. Molecular regulation of fetal growth and prenatal heart development

    Article • Journal of the American Heart Association, August 2017, Wolters Kluwer Health

    Dr Jörg-Detlef Drenckhahn

  8. Stress response of the hypoplastic mouse heart

    Article • Journal of Developmental Origins of Health and Disease, July 2017, Cambridge University Press

    Dr Jörg-Detlef Drenckhahn

  9. Preserved Heart Function after Left Ventricular Pressure Overload in Adult Mice Subjected to Neonatal Cardiac Hypoplasia

    Article • The Thoracic and Cardiovascular Surgeon, February 2017, Thieme Publishing Group

    Dr Jörg-Detlef Drenckhahn

  10. Transcriptional profiling of regenerating embryonic mouse hearts

    Article • Genomics Data, September 2016, Elsevier

    Dr Jörg-Detlef Drenckhahn

  11. Embryonic cardiomyocytes can orchestrate various cell protective mechanisms to survive mitochondrial stress

    Article • Journal of Molecular and Cellular Cardiology, August 2016, Elsevier

    Dr Jörg-Detlef Drenckhahn

  12. Activation of Peroxisome Proliferator–Activated Receptor-δ as Novel Therapeutic Strategy to Prevent In-Stent Restenosis and Stent ThrombosisHighlights

    Article • Arteriosclerosis Thrombosis and Vascular Biology, June 2016, Wolters Kluwer Health

    Dr Seppo Yla-Herttuala, Dr Jörg-Detlef Drenckhahn

  13. Prenatal mTORC1 Inhibition causes Fetal Growth Restriction and Impairs Heart Development

    Article • The Thoracic and Cardiovascular Surgeon, February 2016, Thieme Publishing Group

    Dr Jörg-Detlef Drenckhahn

  14. Neonatal Cardiac Hypoplasia Alters Postnatal Growth and Stress Response in the Murine Heart

    Article • The Thoracic and Cardiovascular Surgeon, June 2015, Thieme Publishing Group

    Dr Jörg-Detlef Drenckhahn

  15. Impaired myocardial development resulting in neonatal cardiac hypoplasia alters postnatal growth and stress response in the heart

    Article • Cardiovascular Research, February 2015, European Society of Cardiology

    Dr Jörg-Detlef Drenckhahn, Timothy Cox

  16. P313Embryonic cardiomyocytes can orchestrate various cell protective mechanisms to survive metabolic stress

    Article • Cardiovascular Research, June 2014, European Society of Cardiology

    Dr Jörg-Detlef Drenckhahn

  17. Fine Mapping of the 1p36 Deletion Syndrome Identifies Mutation of PRDM16 as a Cause of Cardiomyopathy

    Article • The American Journal of Human Genetics, July 2013, Elsevier

    Dr Jörg-Detlef Drenckhahn

  18. Heart Development: Mitochondria in Command of Cardiomyocyte Differentiation

    Article • Developmental Cell, September 2011, Elsevier

    Dr Jörg-Detlef Drenckhahn

  19. Growth plasticity of the embryonic and fetal heart

    Article • BioEssays, December 2009, Wiley

    Dr Jörg-Detlef Drenckhahn

  20. Disruption of the murine dynein light chain gene Tcte3-3 results in asthenozoospermia

    Article • Reproduction, September 2009, Bioscientifica

    Dr Jörg-Detlef Drenckhahn

  21. Compensatory Growth of Healthy Cardiac Cells in the Presence of Diseased Cells Restores Tissue Homeostasis during Heart Development

    Article • Developmental Cell, October 2008, Elsevier

    Dr Jörg-Detlef Drenckhahn, Timothy Cox

  22. Mutations in Sarcomere Protein Genes in Left Ventricular Noncompaction

    Article • Circulation, May 2008, Wolters Kluwer Health

    Dr Jörg-Detlef Drenckhahn

  23. Arrhythmogenic Right Ventricular Cardiomyopathy Type 5 Is a Fully Penetrant, Lethal Arrhythmic Disorder Caused by a Missense Mutation in the TMEM43 Gene

    Article • The American Journal of Human Genetics, April 2008, Elsevier

    Dr Jörg-Detlef Drenckhahn

  24. The impact of implantable cardioverter-defibrillator therapy on survival in autosomal-dominant arrhythmogenic right ventricular cardiomyopathy (ARVD5)

    Article • Journal of the American College of Cardiology, February 2005, Elsevier

    Dr Jörg-Detlef Drenckhahn

  25. Corrigendum: Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy

    Article • Nature Genetics, January 2005, Nature

    Dr Jörg-Detlef Drenckhahn

  26. Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy

    Article • Nature Genetics, October 2004, Nature

    Dr Jörg-Detlef Drenckhahn

  27. Identification of the human ortholog of the t-complex-encoded protein TCTE3 and evaluation as a candidate gene for primary ciliary dyskinesia

    Article • Cytogenetic and Genome Research, February 2003, Karger Publishers

    Dr Jörg-Detlef Drenckhahn

  28. 3-D Imaging of Biomedical Samples

    Article • Wiley

    Dr Jörg-Detlef Drenckhahn, Timothy Cox