All Stories

  1. Multiple LPA3 Receptor Agonist Binding Sites Evidenced Under Docking and Functional Studies

    Article • International Journal of Molecular Sciences, April 2025, MDPI AG

    Dr. J. Adolfo García-Sáinz

  2. Antidepressants interact with an LPA3receptor binding site: functional and docking studies

    Article • March 2025, Cold Spring Harbor Laboratory Press

    Dr. J. Adolfo García-Sáinz

  3. LPA3: Pharmacodynamic Differences Between Lysophosphatidic Acid and Oleoyl-Methoxy Glycerophosphothionate: Biased Agonism, Two Sites

    Article • Receptors, December 2024, MDPI AG

    Dr. J. Adolfo García-Sáinz

  4. LPA3: Pharmacodynamic differences between lysophosphatidic acid and oleoyl-methoxy glycerophosphothionate. Biased agonism, two sites

    Article • September 2024, Cold Spring Harbor Laboratory Press

    Dr. J. Adolfo García-Sáinz

  5. Multiple LPA3 receptor agonist binding sites evidenced under docking and functional studies

    Article • September 2024, Cold Spring Harbor Laboratory Press

    Dr. J. Adolfo García-Sáinz

  6. Lysophosphatidic Acid Receptor 3 (LPA3): Signaling and Phosphorylation Sites

    Article • International Journal of Molecular Sciences, June 2024, MDPI AG

    Dr. J. Adolfo García-Sáinz

  7. LPA3 Receptor Phosphorylation Sites: Roles in Signaling and Internalization

    Article • International Journal of Molecular Sciences, May 2024, MDPI AG

    Dr. J. Adolfo García-Sáinz

  8. Lysophosphatidic Acid Receptor 3 (LPA3): Signaling and Phosphorylation Sites

    Article • April 2024, MDPI AG

    Dr. J. Adolfo García-Sáinz

  9. LPA3 Receptor Phosphorylation Sites: Roles in Signaling and Internalization

    Article • April 2024, MDPI AG

    Dr. J. Adolfo García-Sáinz

  10. Roles of the α1B-Adrenergic Receptor Phosphorylation Domains in Signaling and Internalization

    Article • International Journal of Molecular Sciences, November 2023, MDPI AG

    Dr. J. Adolfo García-Sáinz

  11. Lysophosphatidic acid receptor LPA1 trafficking and interaction with Rab proteins, as evidenced by Förster resonance energy transfer

    Article • Molecular and Cellular Endocrinology, June 2023, Elsevier

    Dr. J. Adolfo García-Sáinz

  12. Cell Trafficking and Function of G Protein-coupled Receptors

    Article • Archives of Medical Research, July 2022, Elsevier

    Dr. J. Adolfo García-Sáinz

  13. Mutation of putative phosphorylation sites in the free fatty acid receptor 1: Effects on signaling, receptor phosphorylation, and internalization

    Article • Molecular and Cellular Endocrinology, April 2022, Elsevier

    Dr. J. Adolfo García-Sáinz

  14. Roles of Receptor Phosphorylation and Rab Proteins in G Protein-Coupled Receptor Function and Trafficking

    Article • Molecular Pharmacology, March 2022, Elsevier

    Dr. J. Adolfo García-Sáinz

  15. The LPA3 Receptor: Regulation and Activation of Signaling Pathways

    Article • International Journal of Molecular Sciences, June 2021, MDPI AG

    Dr. J. Adolfo García-Sáinz

  16. Updates in the function and regulation of α1‐adrenoceptors

    Article • British Journal of Pharmacology, April 2019, Wiley

    Dr. J. Adolfo García-Sáinz

  17. Distinct phosphorylation sites/clusters in the carboxyl terminus regulate α1D-adrenergic receptor subcellular localization and signaling

    Article • Cellular Signalling, January 2019, Elsevier

    Dr. J. Adolfo García-Sáinz

  18. S1P1 receptor phosphorylation, internalization, and interaction with Rab proteins: effects of sphingosine 1-phosphate, FTY720-P, phorbol esters, and paroxetine

    Article • Bioscience Reports, October 2018, Portland Press Ltd.

    Dr. J. Adolfo García-Sáinz

  19. Protein Kinase C Activation Promotes α1B-Adrenoceptor Internalization and Late Endosome Trafficking through Rab9 Interaction. Role in Heterologous Desensitization

    Article • Molecular Pharmacology, January 2017, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr. J. Adolfo García-Sáinz

  20. Novel Structural Approaches to Study GPCR Regulation

    Article • International Journal of Molecular Sciences, December 2016, MDPI AG

    Dr. J. Adolfo García-Sáinz

  21. A Latin American Perspective on G Protein–Coupled Receptors

    Article • Molecular Pharmacology, October 2016, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr. J. Adolfo García-Sáinz

  22. α1B-Adrenergic Receptors Differentially Associate with Rab Proteins during Homologous and Heterologous Desensitization

    Article • PLOS One, March 2015, PLOS

    Dr. J. Adolfo García-Sáinz

  23. Visualizing G Protein-coupled Receptors in Action through Confocal Microscopy Techniques

    Article • Archives of Medical Research, May 2014, Elsevier

    Dr. J. Adolfo García-Sáinz

  24. Isoforms of protein kinase C involved in phorbol ester-induced sphingosine 1-phosphate receptor 1 phosphorylation and desensitization

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, February 2014, Elsevier

    Dr. J. Adolfo García-Sáinz

  25. Conventional protein kinase C isoforms mediate phorbol ester-induced lysophosphatidic acid LPA1 receptor phosphorylation

    Article • European Journal of Pharmacology, January 2014, Elsevier

    Dr. J. Adolfo García-Sáinz

  26. Free fatty acids and protein kinase C activation induce GPR120 (free fatty acid receptor 4) phosphorylation

    Article • European Journal of Pharmacology, January 2014, Elsevier

    Dr. J. Adolfo García-Sáinz

  27. Differential Phosphorylation, Desensitization, and Internalization of α1A−Adrenoceptors Activated by Norepinephrine and Oxymetazoline

    Article • Molecular Pharmacology, January 2013, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr. J. Adolfo García-Sáinz

  28. Sphingosine 1-phosphate-mediated α1B-adrenoceptor desensitization and phosphorylation. Direct and paracrine/autocrine actions

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, February 2012, Elsevier

    Dr. J. Adolfo García-Sáinz

  29. Roles of phosphoinositide-dependent kinase-1 in α1B-adrenoceptor phosphorylation and desensitization

    Article • European Journal of Pharmacology, January 2012, Elsevier

    Dr. J. Adolfo García-Sáinz

  30. EGF and angiotensin II modulate lysophosphatidic acid LPA1 receptor function and phosphorylation state

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, December 2011, Elsevier

    Dr. J. Adolfo García-Sáinz

  31. Mechanisms involved in α1B-adrenoceptor desensitization

    Article • IUBMB Life, August 2011, Wiley

    Dr. J. Adolfo García-Sáinz

  32. Dissecting how receptor tyrosine kinases modulate G protein-coupled receptor function

    Article • European Journal of Pharmacology, December 2010, Elsevier

    Dr. J. Adolfo García-Sáinz

  33. Roles of the α1A-adrenergic receptor carboxyl tail in protein kinase C-induced phosphorylation and desensitization

    Article • Naunyn-Schmiedeberg s Archives of Pharmacology, October 2010, Springer Science + Business Media

    Dr. J. Adolfo García-Sáinz

  34. α1D-Adrenergic Receptors

    Article • January 2010, Elsevier

    Dr. J. Adolfo García-Sáinz

  35. Receptor tyrosine kinases regulate α1D-adrenoceptor signaling properties: Phosphorylation and desensitization

    Article • The International Journal of Biochemistry & Cell Biology, June 2009, Elsevier

    Dr. J. Adolfo García-Sáinz

  36. Signaling properties of human α1D-adrenoceptors lacking the carboxyl terminus: intrinsic activity, agonist-mediated activation, and desensitization

    Article • Naunyn-Schmiedeberg s Archives of Pharmacology, May 2009, Springer Science + Business Media

    Dr. J. Adolfo García-Sáinz

  37. Effect of inhibitors of mitogen-activated protein kinase kinase on α1B-adrenoceptor phosphorylation

    Article • Autonomic and Autacoid Pharmacology, January 2009, Wiley

    Dr. J. Adolfo García-Sáinz

  38. G Protein-Coupled Receptor-Receptor Tyrosine Kinase Receptor Crosstalk: Regulation of Receptor Sensitivity and Roles of Autocrine Feedback Loops and Signal Integration

    Article • Current Signal Transduction Therapy, September 2008, Bentham Science Publishers

    Dr. J. Adolfo García-Sáinz

  39. Regulation of LPA receptor function by estrogens

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, February 2008, Elsevier

    Dr. J. Adolfo García-Sáinz

  40. Phosphorylation, desensitization and internalization of human α1B-adrenoceptors induced by insulin-like growth factor-I

    Article • European Journal of Pharmacology, January 2008, Elsevier

    Dr. J. Adolfo García-Sáinz

  41. Roles of c-Src in α1B-adrenoceptor phosphorylation and desensitization

    Article • Autonomic and Autacoid Pharmacology, January 2008, Wiley

    Dr. J. Adolfo García-Sáinz

  42. Lysophosphatidic acid LPA1 receptor close-up

    Article • Signal Transduction, December 2007, Wiley

    Dr. J. Adolfo García-Sáinz

  43. Editorial: Signal transduction in Mexico

    Article • Signal Transduction, December 2007, Wiley

    Dr. J. Adolfo García-Sáinz

  44. Insulin-Like Growth Factor-I Induces α1B-Adrenergic Receptor Phosphorylation through Gβγ and Epidermal Growth Factor Receptor Transactivation

    Article • Molecular Endocrinology, November 2006, Endocrine Society

    Dr. J. Adolfo García-Sáinz

  45. Role of epidermal growth factor receptor transactivation in α1B-adrenoceptor phosphorylation

    Article • European Journal of Pharmacology, August 2006, Elsevier

    Dr. J. Adolfo García-Sáinz

  46. Estrogens Cross-Talk to α1b-Adrenergic Receptors

    Article • Molecular Pharmacology, April 2006, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr. J. Adolfo García-Sáinz

  47. Okadaic acid increases the phosphorylation state of α1A-adrenoceptors and induces receptor desensitization

    Article • European Journal of Pharmacology, November 2005, Elsevier

    Dr. J. Adolfo García-Sáinz

  48. Agonist-Induced Interactions between Angiotensin AT1 and Epidermal Growth Factor Receptors

    Article • Molecular Pharmacology, May 2005, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr. J. Adolfo García-Sáinz

  49. Phosphorylation and desensitization of the lysophosphatidic acid receptor LPA1

    Article • Biochemical Journal, February 2005, Portland Press Ltd.

    Dr. J. Adolfo García-Sáinz

  50. The elusive α1D-adrenoceptor: molecular and cellular characteristics and integrative roles

    Article • European Journal of Pharmacology, October 2004, Elsevier

    Dr. J. Adolfo García-Sáinz

  51. Insulin induces α1B-adrenergic receptor phosphorylation and desensitization

    Article • Life Sciences, September 2004, Elsevier

    Dr. J. Adolfo García-Sáinz

  52. Human α1D-adrenoceptor phosphorylation and desensitization

    Article • Biochemical Pharmacology, May 2004, Elsevier

    Dr. J. Adolfo García-Sáinz

  53. Peroxovanadate induces $alpha;1B-adrenoceptor phosphorylation and association with protein kinase C

    Article • European Journal of Pharmacology, February 2004, Elsevier

    Dr. J. Adolfo García-Sáinz

  54. Lysophosphatidic acid induces $alpha;1B-adrenergic receptor phosphorylation through G$beta;$gamma;, phosphoinositide 3-kinase, protein kinase C and epidermal growth factor receptor transactivation

    Article • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, July 2003, Elsevier

    Dr. J. Adolfo García-Sáinz

  55. G protein-coupled receptor cross-talk: pivotal roles of protein phosphorylation and protein?protein interactions

    Article • Cellular Signalling, June 2003, Elsevier

    Dr. J. Adolfo García-Sáinz

  56. α1B-Adrenergic receptor phosphorylation and desensitization induced by transforming growth factor-β

    Article • Biochemical Journal, December 2002, Portland Press Ltd.

    Dr. J. Adolfo García-Sáinz

  57. Molecular cloning and functional expression of the guinea pig α1a-adrenoceptor

    Article • European Journal of Pharmacology, August 2001, Elsevier

    Dr. J. Adolfo García-Sáinz

  58. Protein kinase C-α1b-adrenoceptor coimmunoprecipitation: effect of hormones and phorbol myristate acetate

    Article • European Journal of Pharmacology, May 2001, Elsevier

    Dr. J. Adolfo García-Sáinz

  59. Phosphorylation and desensitization of α1d-adrenergic receptors

    Article • Biochemical Journal, February 2001, Portland Press Ltd.

    Dr. J. Adolfo García-Sáinz

  60. Cross-talk between receptors with intrinsic tyrosine kinase activity and α1b-adrenoceptors

    Article • Biochemical Journal, September 2000, Portland Press Ltd.

    Dr. J. Adolfo García-Sáinz

  61. Norepinephrine- and Phorbol Ester-induced Phosphorylation of α1a-Adrenergic Receptors

    Article • Journal of Biological Chemistry, February 2000, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr. J. Adolfo García-Sáinz

  62. α1-Adrenoceptors: function and phosphorylation

    Article • European Journal of Pharmacology, February 2000, Elsevier

    Dr. J. Adolfo García-Sáinz

  63. Protein kinase C-mediated phosphorylation and desensitization of human α1b-adrenoceptors

    Article • European Journal of Pharmacology, December 1999, Elsevier

    Dr. J. Adolfo García-Sáinz

  64. Inverse α1A and α1D adrenoceptor mRNA expression during isolation of hepatocytes

    Article • European Journal of Pharmacology, November 1999, Elsevier

    Dr. J. Adolfo García-Sáinz

  65. α1-Adrenoceptors

    Article • Archives of Medical Research, November 1999, Elsevier

    Dr. J. Adolfo García-Sáinz

  66. Intracellular Calcium and α1b-Adrenoceptor Phosphorylation

    Article • Archives of Medical Research, September 1999, Elsevier

    Dr. J. Adolfo García-Sáinz

  67. Modulation of basal intracellular calcium by inverse agonists and phorbol myristate acetate in rat-1 fibroblasts stably expressing α1d -adrenoceptors

    Article • FEBS Letters, January 1999, Wiley

    Dr. J. Adolfo García-Sáinz

  68. Angiotensin AT1 receptors in Clone 9 rat liver cells: Ca2+ signaling and c-fos expression

    Article • European Journal of Pharmacology, December 1998, Elsevier

    Dr. J. Adolfo García-Sáinz

  69. Crosstalk: phosphorylation of α1b -adrenoceptors induced through activation of bradykinin B2 receptors

    Article • FEBS Letters, January 1998, Wiley

    Dr. J. Adolfo García-Sáinz

  70. Chloroquine inhibits α1B-adrenergic action in hepatocytes

    Article • European Journal of Pharmacology, January 1998, Elsevier

    Dr. J. Adolfo García-Sáinz

  71. α1-Adrenoceptor subtype activation increases proto-oncogene mRNA levels. Role of protein kinase C

    Article • European Journal of Pharmacology, January 1998, Elsevier

    Dr. J. Adolfo García-Sáinz

  72. Activation of Endothelin ETAReceptors Induces Phosphorylation of α1b-Adrenoreceptors in Rat-1 Fibroblasts

    Article • Journal of Biological Chemistry, October 1997, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr. J. Adolfo García-Sáinz

  73. Atypical angiotensin II receptors coupled to phosphoinositide turnover/calcium signalling in catfish hepatocytes

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, June 1997, Elsevier

    Dr. J. Adolfo García-Sáinz

  74. Purification and Characterization of Receptors for Activated Protein Kinase C from Rat Hepatocytes

    Article • Protein Expression and Purification, June 1997, Elsevier

    Dr. J. Adolfo García-Sáinz

  75. Hormonal Responsiveness of Hepatocytes After Hypothermic Preservation in University of Wisconsin Solution

    Article • Cellular Signalling, May 1997, Elsevier

    Dr. J. Adolfo García-Sáinz

  76. Characterization of the β2 adrenoceptors of dog liver

    Article • Comparative Biochemistry and Physiology Part C Pharmacology Toxicology and Endocrinology, September 1996, Elsevier

    Dr. J. Adolfo García-Sáinz

  77. Coexpression of α1A- and α1B-adrenoceptors in the liver of the rhesus monkey (Macaca mulatta)

    Article • European Journal of Pharmacology, September 1996, Elsevier

    Dr. J. Adolfo García-Sáinz

  78. Characterization of the α1-adrenoceptors of cat liver. Predominance of the α1A-adrenergic subtype

    Article • Life Sciences, June 1996, Elsevier

    Dr. J. Adolfo García-Sáinz

  79. Hormonal modulation of c-fos expression in isolated hepatocytes. Effects of angiotensin II and phorbol myristate acetate on transcription and mRNA degradation

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, February 1996, Elsevier

    Dr. J. Adolfo García-Sáinz

  80. Characterization of the human liver α1-adrenoceptors: predominance of the α1A subtype

    Article • European Journal of Pharmacology Molecular Pharmacology, March 1995, Elsevier

    Dr. J. Adolfo García-Sáinz

  81. α1-Adrenoceptor subtype selectivity of tamsulosin: Studies using livers from different species

    Article • European Journal of Pharmacology Molecular Pharmacology, March 1995, Elsevier

    Dr. J. Adolfo García-Sáinz

  82. Protein kinases and phosphatases modulate c-fos expression in rat hepatocytes. effects of angiotensin II and phorbol myristate acetate

    Article • Life Sciences, January 1995, Elsevier

    Dr. J. Adolfo García-Sáinz

  83. Characterization of the α1B-Adrenoceptors of Catfish Hepatocytes: Functional and Binding Studies

    Article • General and Comparative Endocrinology, January 1995, Elsevier

    Dr. J. Adolfo García-Sáinz

  84. Characterization of the α1-adrenoceptors of dog liver: predominance of the α1A-subtype

    Article • European Journal of Pharmacology, January 1995, Elsevier

    Dr. J. Adolfo García-Sáinz

  85. Glycyl-histidyl-lysine interacts with the angiotensin II AT1 receptor

    Article • Peptides, January 1995, Elsevier

    Dr. J. Adolfo García-Sáinz

  86. Inhibition of hormone-stimulated inositol phosphate production and disruption of cytoskeletal structure. Effects of okadaic acid, microcystin, chlorpromazine, W7 and nystatin

    Article • Toxicon, January 1994, Elsevier

    Marina Macias-Silva, Dr. J. Adolfo García-Sáinz

  87. Characterization of the hepatic α1B-adrenoceptors of rats, mice and hamsters

    Article • Life Sciences, January 1994, Elsevier

    Dr. J. Adolfo García-Sáinz

  88. Characterization of the α1B-adrenergic receptors of chicken hepatocytes. Signal transduction and actions

    Article • Comparative Biochemistry and Physiology Part C Pharmacology Toxicology and Endocrinology, November 1993, Elsevier

    Dr. J. Adolfo García-Sáinz

  89. α1-adrenergic action: Receptor subtypes, signal transduction and regulation

    Article • Cellular Signalling, September 1993, Elsevier

    Dr. J. Adolfo García-Sáinz

  90. Hepatocyte homologous β2-adrenergic desensitization is associated with a decrease in number of plasma membrane β2-adrenoceptors

    Article • European Journal of Pharmacology Molecular Pharmacology, January 1993, Elsevier

    Dr. J. Adolfo García-Sáinz

  91. Guinea pig hepatocyte α1A-adrenoceptors: characterization, signal transduction and regulation

    Article • European Journal of Pharmacology Molecular Pharmacology, November 1992, Elsevier

    Marina Macias-Silva, Dr. J. Adolfo García-Sáinz

  92. Histamine activates phosphorylase and inositol phosphate production in guinea pig hepatocytes

    Article • European Journal of Pharmacology Molecular Pharmacology, November 1992, Elsevier

    Marina Macias-Silva, Dr. J. Adolfo García-Sáinz

  93. Angiotensin II and active phorbol esters induce proto-oncogene expression in isolated rat hepatocytes

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, September 1992, Elsevier

    Dr. J. Adolfo García-Sáinz

  94. Species heterogeneity of hepatic α1-adrenoceptors: α1A-, α1B- and α1C-subtypes

    Article • Biochemical and Biophysical Research Communications, July 1992, Elsevier

    Marina Macias-Silva, Dr. J. Adolfo García-Sáinz

  95. Modulation by protein kinase C of the hormonal responsiveness of hepatocytes from lean (Fa/fa?) and obese (fa/fa) Zucker rats

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, June 1992, Elsevier

    Dr. J. Adolfo García-Sáinz

  96. Characterization and detoxification of an easily prepared acellular pertussis vaccine. Antigenic role of the A protomer of pertussis toxin

    Article • Vaccine, January 1992, Elsevier

    Dr. J. Adolfo García-Sáinz

  97. Effect of okadaic acid on hormone- and mastoparan-stimulated phosphoinositide turnover in isolated rat hepatocytes

    Article • Biochemical and Biophysical Research Communications, September 1991, Elsevier

    Marina Macias-Silva, Dr. J. Adolfo García-Sáinz

  98. Differences in phorbol ester-induced decrease of the activity of protein kinase C isozymes in rat hepatocytes

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, August 1991, Elsevier

    Dr. J. Adolfo García-Sáinz

  99. α1-Adrenoceptor subtypes in aorta (α1A) and liver (α1B)

    Article • European Journal of Pharmacology Molecular Pharmacology, March 1991, Elsevier

    Dr. J. Adolfo García-Sáinz

  100. Activation of protein kinase C inhibits hormonal stimulation of the GTPase activity of Gi in human platelets

    Article • FEBS Letters, February 1991, Wiley

    Dr. J. Adolfo García-Sáinz

  101. Angiotensin II stimulates phosphoinositide turnover and phosphorylase through AII-1 receptors in isolated rat hepatocytes

    Article • Biochemical and Biophysical Research Communications, October 1990, Elsevier

    Marina Macias-Silva, Dr. J. Adolfo García-Sáinz

  102. Contrasting effects of phorbol dibutyrate and phorbol myristate acetate in rabbit aorta

    Article • Biochemical and Biophysical Research Communications, September 1990, Elsevier

    Dr. J. Adolfo García-Sáinz

  103. Modulation of glucagon actions by phorbol myristate acetate in isolated hepatocytes. Effect of hypothyroidism

    Article • Cellular Signalling, January 1990, Elsevier

    Marina Macias-Silva, Dr. J. Adolfo García-Sáinz

  104. Activation of protein kinase C alters the interaction of α2 -adrenoceptors and the inhibitory GTP-binding protein (Gi ) in human platelets

    Article • FEBS Letters, November 1989, Wiley

    Dr. J. Adolfo García-Sáinz

  105. Beta1-adrenoceptors in rat hepatoma. Desensitization by isoproterenol and phorbol-myristate-acetate

    Article • Life Sciences, January 1989, Elsevier

    Dr. J. Adolfo García-Sáinz

  106. Intercellular communication within the liver has clinical implications

    Article • Trends in Pharmacological Sciences, January 1989, Elsevier

    Dr. J. Adolfo García-Sáinz

  107. Homologous and heterologous β-adrenergic desensitization in hepatocytes. Additivity and effect of pertussis toxin

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, December 1988, Elsevier

    Marina Macias-Silva, Dr. J. Adolfo García-Sáinz

  108. ‘Inhibitory’ receptors and ion channel effectors

    Article • Trends in Pharmacological Sciences, August 1988, Elsevier

    Dr. J. Adolfo García-Sáinz

  109. Multiple species and isoforms of Bordetella pertussis toxin substrates

    Article • Biochemical and Biophysical Research Communications, May 1988, Elsevier

    Dr. J. Adolfo García-Sáinz

  110. Effect of phorbol esters on the hormonal responsiveness of isolated white fat cells

    Article • European Journal of Pharmacology, February 1988, Elsevier

    Dr. J. Adolfo García-Sáinz

  111. Phorbol esters and calcium-mobilizing hormones increase membrane-associated protein kinase C activity in rat hepatocytes

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, January 1988, Elsevier

    Dr. J. Adolfo García-Sáinz

  112. Angiotensin II receptors: one type coupled to two signals or receptor subtypes?

    Article • Trends in Pharmacological Sciences, February 1987, Elsevier

    Dr. J. Adolfo García-Sáinz

  113. Insulin-like effect of epidermal growth factor in isolated rat hepatocytes

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, November 1986, Elsevier

    Dr. J. Adolfo García-Sáinz

  114. Effect of pertussis toxin on the heart acetylcholine muscarinic receptor affinity

    Article • European Journal of Pharmacology, August 1986, Elsevier

    Dr. J. Adolfo García-Sáinz

  115. Effect of pertussis toxin on the heart muscarinic-cholinergic receptors and their function

    Article • Life Sciences, August 1986, Elsevier

    Dr. J. Adolfo García-Sáinz

  116. Homologous and heterologous desensitization of one of the pathways of the α1-adrenergic action. Effects of epinephrine, vasopressin, angiotensin II and phorbol 12-myristate 13-acetate

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, June 1986, Elsevier

    Dr. J. Adolfo García-Sáinz

  117. Phorbol esters, vasopressin and angiotensin II block α1-adrenergic action in rat hepatocytes. Possible role of protein kinase C

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, June 1986, Elsevier

    Dr. J. Adolfo García-Sáinz

  118. Possible existence of two mechanisms involved in α1-adrenergic action: Effect of Sgd 101/75

    Article • European Journal of Pharmacology, June 1986, Elsevier

    Dr. J. Adolfo García-Sáinz

  119. Pertussis toxin effects on adenylate cyclase activity, cyclic AMP accumulation and lipolysis in adipocytes from hypothyroid, euthyroid and hyperthyroid rats

    Article • Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, May 1986, Elsevier

    Dr. J. Adolfo García-Sáinz

  120. Effects of [1-Nα-trinitrophenylhistidine, 12-homoarginine]glucagon on cyclic AMP levels and free fatty acid release in isolated rat adipocytes

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, April 1986, Elsevier

    Dr. J. Adolfo García-Sáinz

  121. Pertussis toxin enhances the beta-adrenergic and blocks the alpha-adrenergic regulation of renin secretion in renal cortical slices

    Article • Life Sciences, March 1986, Elsevier

    Dr. J. Adolfo García-Sáinz

  122. Effect of pertussis toxin on water metabolism in the rat

    Article • Life Sciences, January 1986, Elsevier

    Dr. J. Adolfo García-Sáinz

  123. Guanine nucleotide-induced positive cooperativity in muscarinic-cholinergic antagonist binding

    Article • Biochemical and Biophysical Research Communications, January 1986, Elsevier

    Dr. J. Adolfo García-Sáinz

  124. Hormonal responsiveness of liver cells during the liver regeneration process induced by carbon tetrachloride administration

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, January 1986, Elsevier

    Dr. J. Adolfo García-Sáinz

  125. Pertussis toxin and the heart

    Article • Trends in Pharmacological Sciences, January 1986, Elsevier

    Dr. J. Adolfo García-Sáinz

  126. Stimulation of hepatic glycogenolysis by 12-O-tetradecanoyl-phorbol-13-acetate (TPA) via cyclooxygenase products

    Article • Biochemical and Biophysical Research Communications, October 1985, Elsevier

    Dr. J. Adolfo García-Sáinz

  127. Differential effects of adrenergic agonists and phorbol esters on the α1-adrenoceptors of hepatocytes and aorta

    Article • European Journal of Pharmacology, June 1985, Elsevier

    Dr. J. Adolfo García-Sáinz

  128. Differential selectivities of RU 24969 and 8-OH-DPAT for the purported 5-HT1A and 5-HT1B binding sites. Correlation between 5-HT1A affinity and hypotensive activity

    Article • European Journal of Pharmacology, June 1985, Elsevier

    Dr. J. Adolfo García-Sáinz

  129. Pertussis toxin potentiates anesthesia-induced renin secretion

    Article • European Journal of Pharmacology, May 1985, Elsevier

    Dr. J. Adolfo García-Sáinz

  130. Possible involvement of two mechanisms of signal transduction in α1-adrenergic action. Selective effect of cycloheximide

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, April 1985, Elsevier

    Dr. J. Adolfo García-Sáinz

  131. Transmodulation, receptor phosphorylation and protein kinases

    Article • Trends in Pharmacological Sciences, January 1985, Elsevier

    Dr. J. Adolfo García-Sáinz

  132. α1-Adrenergic and M1-muscarinic actions and signal propagation

    Article • Trends in Pharmacological Sciences, January 1985, Elsevier

    Dr. J. Adolfo García-Sáinz

  133. Pertussis toxin catalyzes the ADP-ribosylation of two distinct peptides, 40 and 41 kDa, in rat fat cell membranes

    Article • FEBS Letters, October 1984, Wiley

    Dr. J. Adolfo García-Sáinz

  134. Effect of pertussis toxin on the adrenergic regulation of plasma renin activity

    Article • Life Sciences, October 1984, Elsevier

    Dr. J. Adolfo García-Sáinz

  135. Forskolin effects on the beta-adrenergic responsiveness of rat hepatocytes

    Article • Biochemical Pharmacology, October 1984, Elsevier

    Dr. J. Adolfo García-Sáinz

  136. Possible involvement of cyclooxygenase products in the actions of platelet-activating factor and of lipoxygenase products in the vascular effects of epinephrine in perfused rat liver

    Article • Biochemical and Biophysical Research Communications, September 1984, Elsevier

    Dr. J. Adolfo García-Sáinz

  137. Effects of adenosine on liver cell damage induced by carbon tetrachloride

    Article • Biochemical Pharmacology, August 1984, Elsevier

    Dr. J. Adolfo García-Sáinz

  138. Metabolic effects and cyclic AMP levels produced by glucagon, (1-Nα-trinitrophenylhistidine,12-homoarginine)glucagon and forskolin in isolated rat hepatocytes

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, August 1984, Elsevier

    Dr. J. Adolfo García-Sáinz

  139. Effect of pertussis toxin on α2 -adrenoceptors: decreased formation of the high-affinity state for agonists

    Article • FEBS Letters, June 1984, Wiley

    Dr. J. Adolfo García-Sáinz

  140. Pertussis toxin blocks the action of morphine, norepinephrine and clonidine on isolated guinea-pig ileum

    Article • European Journal of Pharmacology, May 1984, Elsevier

    Dr. J. Adolfo García-Sáinz

  141. Activation of lipolysis and cyclic AMP accumulation in rabbit adipocytes by isoproterenol in the presence of forskolin or pertussis toxin

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, April 1984, Elsevier

    Dr. J. Adolfo García-Sáinz

  142. RX781094 a potent and selective α2-adrenergic antagonist. Effects in adipocytes and hepatocytes

    Article • European Journal of Pharmacology, April 1984, Elsevier

    Dr. J. Adolfo García-Sáinz

  143. Direct action of pertussis toxin in isolated hamster fat cells

    Article • European Journal of Pharmacology, March 1984, Elsevier

    Dr. J. Adolfo García-Sáinz

  144. Phorbol esters inhibit alpha1 adrenergic stimulation of glycogenolysis in isolated rat hepatocytes

    Article • Biochemical and Biophysical Research Communications, March 1984, Elsevier

    Dr. J. Adolfo García-Sáinz

  145. Modulation by thyroid status of cyclic AMP-dependent and Ca2+-dependent mechanisms of hormone action in rat liver cells

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, February 1984, Elsevier

    Dr. J. Adolfo García-Sáinz

  146. Adrenergic regulation of ureogenesis in hepatocytes from adrenalectomized rats

    Article • FEBS Letters, January 1984, Wiley

    Dr. J. Adolfo García-Sáinz

  147. Effect of insulin on alpha1-adrenergic actions in hepatocytes from euthyroid and hypothyroid rats

    Article • Biochemical and Biophysical Research Communications, January 1984, Elsevier

    Dr. J. Adolfo García-Sáinz

  148. Pertussis toxin induces tachycardia and impairs the increase in blood pressure produced by alpha2-adrenergic agonists

    Article • Life Sciences, December 1983, Elsevier

    Dr. J. Adolfo García-Sáinz

  149. Effect of pertussis toxin on the hormonal regulation of cyclic AMP levels in hamster fat cells

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, October 1983, Elsevier

    Dr. J. Adolfo García-Sáinz

  150. Pertussis toxin reverses Gpp(NH)p inhibition of basal and forskolin activated adipocyte adenylate cyclase

    Article • Biochemical and Biophysical Research Communications, October 1983, Elsevier

    Dr. J. Adolfo García-Sáinz

  151. Inositol administration restores the sensitivity of liver cells formed during liver regeneration to alpha1-adrenergic amines, vasopressin and angiotensin II

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, September 1983, Elsevier

    Dr. J. Adolfo García-Sáinz

  152. Roles of alpha1- and beta-adrenergic receptors in adrenergic responsiveness of liver cells formed after partial hepatectomy

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, September 1983, Elsevier

    Dr. J. Adolfo García-Sáinz

  153. Sensitivity of liver cells formed after partial hepatectomy to glucagon, vasopressin and angiotensin II

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, September 1983, Elsevier

    Dr. J. Adolfo García-Sáinz

  154. Effect of pertussis toxin on hormonal responsiveness of rat hepatocytes

    Article • FEBS Letters, August 1983, Wiley

    Dr. J. Adolfo García-Sáinz

  155. H1-histaminergic activation stimulates phosphatidylinositol labeling in rabbit aorta

    Article • European Journal of Pharmacology, June 1983, Elsevier

    Dr. J. Adolfo García-Sáinz

  156. Hypothyroidism abolishes the glycogenolytic effect of vasopressin, angiotensin II and A23187 but not that of α1 -adrenergic amines in rat hepatocytes

    Article • FEBS Letters, March 1983, Wiley

    Dr. J. Adolfo García-Sáinz

  157. Bordetella pertussis toxin and adenylate cyclase

    Article • Trends in Pharmacological Sciences, January 1983, Elsevier

    Dr. J. Adolfo García-Sáinz

  158. α1-Adrenergic action: only calcium?

    Article • Trends in Pharmacological Sciences, January 1983, Elsevier

    Dr. J. Adolfo García-Sáinz

  159. Characterization of the α1-adrenoceptors of rat white fat cells

    Article • European Journal of Pharmacology, January 1983, Elsevier

    Dr. J. Adolfo García-Sáinz

  160. Vasopressin and angiotensin II stimulate ureogenesis through increased mitochondrial citrulline production.

    Article • Life Sciences, November 1982, Elsevier

    Dr. J. Adolfo García-Sáinz

  161. Effect of pertussis vaccine on α-adrenoceptors of the circulatory system of the rat

    Article • European Journal of Pharmacology, September 1982, Elsevier

    Dr. J. Adolfo García-Sáinz

  162. Stimulation of ureogenesis through α1- and β-adrenoceptors in juvenile rat hepatocytes

    Article • European Journal of Pharmacology, August 1982, Elsevier

    Dr. J. Adolfo García-Sáinz

  163. Angiotensin II inhibits the accumulation of cyclic AMP produced by glucagon but not its metabolic effects

    Article • FEBS Letters, June 1982, Wiley

    Dr. J. Adolfo García-Sáinz

  164. Cycloheximide: An adrenergic agent

    Article • Life Sciences, May 1982, Elsevier

    Dr. J. Adolfo García-Sáinz

  165. Regulation of adipose tissue metabolism by catecholamines: roles of alpha1, alpha2 and beta-adrenoceptors

    Article • Trends in Pharmacological Sciences, January 1982, Elsevier

    Dr. J. Adolfo García-Sáinz

  166. Two types of alpha adrenoceptors in liver cells

    Article • Trends in Pharmacological Sciences, January 1982, Elsevier

    Dr. J. Adolfo García-Sáinz

  167. Effect of thyroid status on α- and β-catecholamine responsiveness of hamster adipocytes

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, December 1981, Elsevier

    Dr. J. Adolfo García-Sáinz

  168. Effects of pertussis vaccine on the lipid metabolism of hamsters

    Article • Life Sciences, September 1981, Elsevier

    Dr. J. Adolfo García-Sáinz

  169. α1-adrenoceptor activation stimulates ureogenesis in rat hepatocytes

    Article • European Journal of Pharmacology, July 1981, Elsevier

    Dr. J. Adolfo García-Sáinz

  170. Decreased sensitivity to α2 adrenergic amines, adenosine and prostaglandins in white fat cells from hamsters treated with pertussis vaccine

    Article • FEBS Letters, April 1981, Wiley

    Dr. J. Adolfo García-Sáinz

  171. Alpha2 adrenergic amines, adenosine and prostaglandis inhibit lipolysis and cyclic AMP accumulation in hamster adipocytes in the absence of extracellular sodium.

    Article • Life Sciences, January 1981, Elsevier

    Dr. J. Adolfo García-Sáinz

  172. Alpha1-adrenergic activation of phosphatidylinositol labeling in isolated brown fat cells

    Article • Biochemical Pharmacology, December 1980, Elsevier

    Dr. J. Adolfo García-Sáinz

  173. Role of alpha1 adrenoceptors in the turnover of phosphatidylinositol and of alpha2 adrenoceptors in the regulation of cyclic AMP accumulation in hamster adipocytes

    Article • Life Sciences, September 1980, Elsevier

    Dr. J. Adolfo García-Sáinz

  174. Effects of adenosine on ethanol-induced modifications of liver metabolism

    Article • Biochemical Pharmacology, June 1980, Elsevier

    Dr. J. Adolfo García-Sáinz

  175. Role of phosphatidylinositol turnover in alpha1 and of adenylate cyclase inhibition in alpha2 effects of catecholamines

    Article • Life Sciences, April 1980, Elsevier

    Dr. J. Adolfo García-Sáinz

  176. Mechanism of the fatty liver induced by cycloheximide and its reversibility by adenosine

    Article • Biochemical Pharmacology, April 1979, Elsevier

    Dr. J. Adolfo García-Sáinz

  177. On the mechanism of ethanol-induced fatty liver and its reversibility by adenosine

    Article • Archives of Biochemistry and Biophysics, September 1978, Elsevier

    Dr. J. Adolfo García-Sáinz

  178. Importance of the esterification process in adipose tissue metabolism as evidenced by cycloheximide

    Article • Biochemical Pharmacology, January 1978, Elsevier

    Dr. J. Adolfo García-Sáinz

  179. Effect of ethanol and n-butanol on alloxan inhibition of glucose-induced insulin release in isolated pancreatic islets

    Article • Biochemical Pharmacology, January 1978, Elsevier

    Dr. J. Adolfo García-Sáinz

  180. Lipogenic action of cycloheximide on the rat epididymal fat pad

    Article • Biochemical Pharmacology, April 1975, Elsevier

    Dr. J. Adolfo García-Sáinz