All Stories

  1. Discovering skin-rejuvenating matrikines - a basic and applied Dermatology new frontier

    Article • British Journal of Dermatology, March 2024, Oxford University Press (OUP)

    Dr. Ilaria Dal Prà

  2. Human Keratinocytes and Fibroblasts Co-Cultured on Silk Fibroin Scaffolds Exosomally Overrelease Angiogenic and Growth Factors

    Article • Cells, July 2023, MDPI AG

    Dr. Ilaria Dal Prà, Anna Chiarini

  3. NLRP3 Inflammasome’s Activation in Acute and Chronic Brain Diseases—An Update on Pathogenetic Mechanisms and Therapeutic Perspectives with Respect to Other Inflammasomes

    Article • Biomedicines, March 2023, MDPI AG

    Dr. Ilaria Dal Prà, Anna Chiarini

  4. Human EVI2B acts as a Janus-faced oncogene/antioncogene by differently affecting as per cancer type neoplastic cells growth and immune infiltration

    Article • ONCOLOGIE, March 2023, De Gruyter

    Anna Chiarini, Dr. Ilaria Dal Prà

  5. “Other Than NLRP3” Inflammasomes: Multiple Roles in Brain Disease

    Article • The Neuroscientist, July 2022, SAGE Publications

    Dr. Ilaria Dal Prà, Anna Chiarini

  6. Adult Human Vascular Smooth Muscle Cells on 3D Silk Fibroin Nonwovens Release Exosomes Enriched in Angiogenic and Growth-Promoting Factors

    Article • Polymers, February 2022, MDPI AG

    Dr. Ilaria Dal Prà, Anna Chiarini

  7. Electrospun Silk Fibroin Scaffolds for Tissue Regeneration: Chemical, Structural, and Toxicological Implications of the Formic Acid-Silk Fibroin Interaction

    Article • Frontiers in Bioengineering and Biotechnology, January 2022, Frontiers

    Dr. Ilaria Dal Prà, Anna Chiarini

  8. Exosomes of adult human fibroblasts cultured on 3D silk fibroin nonwovens intensely stimulate neoangiogenesis

    Article • Burns & Trauma, January 2021, Oxford University Press (OUP)

    Dr. Ilaria Dal Prà, Anna Chiarini

  9. A novel method for objectively, rapidly and accurately evaluating burn depth via near infrared spectroscopy

    Article • Burns & Trauma, January 2021, Oxford University Press (OUP)

    Dr. Ilaria Dal Prà

  10. Danger-Sensing/Patten Recognition Receptors and Neuroinflammation in Alzheimer’s Disease

    Article • International Journal of Molecular Sciences, November 2020, MDPI AG

    Dr. Ilaria Dal Prà, Anna Chiarini

  11. CaSR Antagonist (Calcilytic) NPS 2143 Hinders the Release of Neuroinflammatory IL-6, Soluble ICAM-1, RANTES, and MCP-2 from Aβ-Exposed Human Cortical Astrocytes

    Article • Cells, June 2020, MDPI AG

    Dr. Ilaria Dal Prà, Anna Chiarini

  12. Linking astrocytes' exosomes to Alzheimer pathogenesis and therapy

    Article • January 2020, Elsevier

    Dr. Ilaria Dal Prà

  13. Mesenchymal stromal cells-exosomes: a promising cell-free therapeutic tool for wound healing and cutaneous regeneration

    Article • Burns & Trauma, December 2019, Oxford University Press (OUP)

    Dr. Ilaria Dal Prà, Anna Chiarini

  14. Three-Layered Silk Fibroin Tubular Scaffold for the Repair and Regeneration of Small Caliber Blood Vessels: From Design to in vivo Pilot Tests

    Article • Frontiers in Bioengineering and Biotechnology, November 2019, Frontiers

    Dr. Ilaria Dal Prà, Anna Chiarini

  15. Family C G-Protein-Coupled Receptors in Alzheimer’s Disease and Therapeutic Implications

    Article • Frontiers in Pharmacology, October 2019, Frontiers

    Dr. Ilaria Dal Prà, Anna Chiarini

  16. Maladaptive remodeling of pulmonary artery root autografts after Ross procedure: A proteomic study

    Article • Journal of Thoracic and Cardiovascular Surgery, August 2019, Elsevier

    Dr. Ilaria Dal Prà, Anna Chiarini

  17. Over Expressed TKTL1, CIP-2A, and B-MYB Proteins in Uterine Cervix Epithelium Scrapings as Potential Risk Predictive Biomarkers in HR-HPV-Infected LSIL/ASCUS Patients

    Article • Frontiers in Oncology, April 2019, Frontiers

    Dr. Ilaria Dal Prà, Anna Chiarini

  18. Studies on sporadic non-syndromic thoracic aortic aneurysms: 1. Deregulation of Jagged/Notch 1 homeostasis and selection of synthetic/secretor phenotype smooth muscle cells

    Article • European Journal of Preventive Cardiology, April 2018, SAGE Publications

    Dr. Ilaria Dal Prà, Anna Chiarini

  19. Studies on sporadic non-syndromic thoracic aortic aneurysms: II. Alterations of extra-cellular matrix components and focal adhesion proteins

    Article • European Journal of Preventive Cardiology, April 2018, SAGE Publications

    Anna Chiarini, Dr. Ilaria Dal Prà

  20. Astrocytes’ Role in Alzheimer’s Disease Neurodegeneration

    Article • March 2018, IntechOpen

    Dr. Ilaria Dal Prà

  21. Targeting Human Astrocytes' Calcium-sensing Receptors for Treatment of Alzheimer's Disease

    Article • Current Pharmaceutical Design, January 2018, Bentham Science Publishers

    Professor Ubaldo Armato, Anna Chiarini, Dr. Ilaria Dal Prà

  22. Calcium-Sensing Receptor Antagonist NPS 2143 Restores Amyloid Precursor Protein Physiological Non-Amyloidogenic Processing in Aβ-Exposed Adult Human Astrocytes

    Article • Scientific Reports, April 2017, Springer Science + Business Media

    Dr. Ilaria Dal Prà, Anna Chiarini

  23. Amyloid β-Exposed Human Astrocytes Overproduce Phospho-Tau and Overrelease It within Exosomes, Effects Suppressed by Calcilytic NPS 2143—Further Implications for Alzheimer's Therapy

    Article • Frontiers in Neuroscience, April 2017, Frontiers

    Dr. Ilaria Dal Prà, Anna Chiarini

  24. Increased Calcium-Sensing Receptor Immunoreactivity in the Hippocampus of a Triple Transgenic Mouse Model of Alzheimer's Disease

    Article • Frontiers in Neuroscience, February 2017, Frontiers

    Dr. Ilaria Dal Prà, Anna Chiarini

  25. Biocompatible Silk Noil-Based Three-Dimensional Carded-Needled Nonwoven Scaffolds Guide the Engineering of Novel Skin Connective Tissue

    Article • Tissue Engineering Part A, August 2016, Mary Ann Liebert Inc

    Dr. Ilaria Dal Prà, Anna Chiarini

  26. Calcium-Sensing Receptors of Human Neural Cells Play Crucial Roles in Alzheimer's Disease

    Article • Frontiers in Physiology, April 2016, Frontiers

    Dr. Ilaria Dal Prà, Anna Chiarini

  27. Evidence for caspase-dependent programmed cell death along with repair processes in affected skeletal muscle fibres in patients with mitochondrial disorders

    Article • Clinical Science, November 2015, Portland Press Ltd.

    Dr. Ilaria Dal Prà, Anna Chiarini

  28. Eukaryotic initiation factor 6 modulates myofibroblast differentiation at transforming growth factor- 1 transcription level via H2A.Z occupancy and Sp1 recruitment

    Article • Journal of Cell Science, September 2015, The Company of Biologists

    Dr. Ilaria Dal Prà

  29. Bcl10 crucially nucleates the pro-apoptotic complexes comprising PDK1, PKCζ and caspase-3 at the nuclear envelope of etoposide-treated human cervical carcinoma C4-I cells

    Article • International Journal of Molecular Medicine, July 2015, Spandidos Publications

    Dr. Ilaria Dal Prà, Anna Chiarini

  30. The Possible Roles of the Dentate Granule Cell’s Leptin and Other Ciliary Receptors in Alzheimer’s Neuropathology

    Article • Cells, July 2015, MDPI AG

    Dr. Ilaria Dal Prà

  31. Preventing the Spread of Alzheimer’s Disease Neuropathology: A Role for Calcilytics?

    Article • Current Pharmaceutical Biotechnology, June 2015, Bentham Science Publishers

    Professor Ubaldo Armato, Dr. Ilaria Dal Prà, Anna Chiarini

  32. Antagonizing amyloid-β/calcium-sensing receptor signaling in human astrocytes and neurons: a key to halt Alzheimer′s disease progression?

    Article • Neural Regeneration Research, January 2015, Medknow

    Professor Ubaldo Armato, Dr. Ilaria Dal Prà, Anna Chiarini

  33. Calcium-Sensing Receptors of Human Astrocyte-Neuron Teams: Amyloid-β-Driven Mediators and Therapeutic Targets of Alzheimer’s Disease

    Article • Current Neuropharmacology, August 2014, Bentham Science Publishers

    Dr. Ilaria Dal Prà

  34. Combining immunofluorescence with in situ proximity ligation assay: a novel imaging approach to monitor protein–protein interactions in relation to subcellular localization

    Article • Histochemistry and Cell Biology, July 2014, Springer Science + Business Media

    Dr. Ilaria Dal Prà, Anna Chiarini

  35. The Aβ Peptides-Activated Calcium-Sensing Receptor Stimulates the Production and Secretion of Vascular Endothelial Growth Factor-A by Normoxic Adult Human Cortical Astrocytes

    Article • NeuroMolecular Medicine, June 2014, Springer Science + Business Media

    Dr. Ilaria Dal Prà, Anna Chiarini

  36. Do Astrocytes Collaborate with Neurons in Spreading the “Infectious” Aβ and Tau Drivers of Alzheimer’s Disease?

    Article • The Neuroscientist, April 2014, SAGE Publications

    Dr. Ilaria Dal Prà, Anna Chiarini

  37. Calcium-sensing receptor antagonist (calcilytic) NPS 2143 specifically blocks the increased secretion of endogenous Aβ42 prompted by exogenous fibrillary or soluble Aβ25–35 in human cortical astrocytes and neurons—Therapeutic relevance to Alzheimer's d...

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, October 2013, Elsevier

    Dr. Ilaria Dal Prà, Anna Chiarini

  38. The calcium-sensing receptor: A novel Alzheimer's disease crucial target?

    Article • Journal of the Neurological Sciences, November 2012, Elsevier

    Dr. Ilaria Dal Prà, Anna Chiarini

  39. Reduction of the immunostainable length of the hippocampal dentate granule cells’ primary cilia in 3xAD-transgenic mice producing human Aβ1-42 and tau

    Article • Biochemical and Biophysical Research Communications, October 2012, Elsevier

    Dr. Ilaria Dal Prà

  40. Role-Shifting PKCζ Fosters Its Own Proapoptotic Destruction by Complexing with Bcl10 at the Nuclear Envelope of Human Cervical Carcinoma Cells: A Proteomic and Biochemical Study

    Article • Journal of Proteome Research, July 2012, American Chemical Society (ACS)

    Dr. Ilaria Dal Prà, Anna Chiarini

  41. Astrocytes may drive a Beta-Amyloid contagion in human Alzheimer's disease brains

    Article • Alzheimer s & Dementia, July 2012, Elsevier

    Dr. Ilaria Dal Prà

  42. Hippocampal Membrane-Associated p75NTR Levels are Increased in Alzheimer's Disease

    Article • Journal of Alzheimer s Disease, June 2012, IOS Press

    Dr. Ilaria Dal Prà

  43. A stable panel comprising 18 urinary proteins in the human healthy population

    Article • PROTEOMICS, April 2012, Wiley

    Dr. Ilaria Dal Prà

  44. Direct screening of herbal blends for new synthetic cannabinoids by MALDI-TOF MS

    Article • Journal of Mass Spectrometry, January 2012, Wiley

    Dr. Ilaria Dal Prà, Anna Chiarini

  45. Leptin, Sonic Hedgehogs, and Neurogenesis- A Primary Cilium’s Taleon

    Article • Journal of Alzheimer’s Disease & Parkinsonism, January 2012, OMICS Publishing Group

    Dr. Ilaria Dal Prà, Anna Chiarini

  46. The Amyloid-β42 Proxy, Amyloid-β25-35, Induces Normal Human Cerebral Astrocytes to Produce Amyloid-β42

    Article • Journal of Alzheimer s Disease, April 2011, IOS Press

    Dr. Ilaria Dal Prà, Anna Chiarini

  47. A Paradigm-Changing Surprise from Dentate Gyrus Granule Cells— Cilium-Localized p75NTR May Drive Their Progenitor Cell Proliferation

    Article • Journal of Alzheimer’s Disease & Parkinsonism, January 2011, OMICS Publishing Group

    Dr. Ilaria Dal Prà, Anna Chiarini

  48. Is Alzheimer’s Disease at Least Partly a Ciliopathy?

    Article • Journal of Alzheimer’s Disease & Parkinsonism, January 2011, OMICS Publishing Group

    Dr. Ilaria Dal Prà, Anna Chiarini

  49. The p75 neurotrophin receptor is localized to primary cilia in adult murine hippocampal dentate gyrus granule cells

    Article • Biochemical and Biophysical Research Communications, October 2010, Elsevier

    Dr. Ilaria Dal Prà, Anna Chiarini

  50. Amyloid-β25–35, an Amyloid-β1–42 Surrogate, and Proinflammatory Cytokines Stimulate VEGF-A Secretion by Cultured, Early Passage, Normoxic Adult Human Cerebral Astrocytes

    Article • Journal of Alzheimer s Disease, September 2010, IOS Press

    Dr. Ilaria Dal Prà, Anna Chiarini

  51. Calphostin C, a remarkable multimodal photodynamic killer of neoplastic cells by selective nuclear lamin B1 destruction and apoptogenesis (Review)

    Article • Oncology Reports, March 2010, Spandidos Publications

    Dr. Ilaria Dal Prà

  52. Calcium-Sensing Receptor (CaSR) in Human Brains Pathophysiology: Roles in Late-Onset Alzheimers Disease (LOAD)

    Article • Current Pharmaceutical Biotechnology, April 2009, Bentham Science Publishers

    Dr. Ilaria Dal Prà, Anna Chiarini

  53. Proteomic analysis of GTP cyclohydrolase 1 multiprotein complexes in cultured normal adult human astrocytes under both basal and cytokine-activated conditions

    Article • PROTEOMICS, April 2009, Wiley

    Dr. Ilaria Dal Prà, Anna Chiarini

  54. Photoexcited calphostin C selectively destroys nuclear lamin B1 in neoplastic human and rat cells — A novel mechanism of action of a photodynamic tumor therapy agent

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, September 2008, Elsevier

    Dr. Ilaria Dal Prà, Anna Chiarini

  55. Comano's (Trentino) thermal water interferes with tumour necrosis factor-α expression and interleukin-8 production and secretion by cultured human psoriatic keratinocytes: Yet other mechanisms of its anti-psoriatic action

    Article • International Journal of Molecular Medicine, March 2007, Spandidos Publications

    Dr. Ilaria Dal Prà

  56. Comano's (Trentino) thermal water interferes with interleukin-6 production and secretion and with cytokeratin-16 expression by cultured human psoriatic keratinocytes: Further potential mechanisms of its anti-psoriatic action

    Article • International Journal of Molecular Medicine, December 2006, Spandidos Publications

    Dr. Ilaria Dal Prà

  57. Comano's (Trentino) thermal water interferes with the expression and secretion of vascular endothelial growth factor-A protein isoforms by cultured human psoriatic keratinocytes: A potential mechanism of its anti-psoriatic action

    Article • International Journal of Molecular Medicine, July 2006, Spandidos Publications

    Dr. Ilaria Dal Prà

  58. De novo engineering of reticular connective tissue in vivo by silk fibroin nonwoven materials

    Article • Biomaterials, May 2005, Elsevier

    Dr. Ilaria Dal Prà, Anna Chiarini

  59. BH4 (tetrahydrobiopterin)-dependent activation, but not the expression, of inducible NOS (nitric oxide synthase)-2 in proinflammatory cytokine-stimulated, cultured normal human astrocytes is mediated by MEK-ERK kinases

    Article • Journal of Cellular Biochemistry, January 2005, Wiley

    Dr. Ilaria Dal Prà, Anna Chiarini

  60. Roles of Ca2+ and the Ca2+-sensing receptor (CASR) in the expression of inducible NOS (nitric oxide synthase)-2 and its BH4 (tetrahydrobiopterin)-dependent activation in cytokine-stimulated adult human astrocytes

    Article • Journal of Cellular Biochemistry, January 2005, Wiley

    Dr. Ilaria Dal Prà, Anna Chiarini

  61. Expression of protein kinase C isoforms and interleukin-1  in myofibrillar myopathy

    Article • Neurology, May 2004, Wolters Kluwer Health

    Dr. Ilaria Dal Prà

  62. Silk Fibroin-Coated Three-Dimensional Polyurethane Scaffolds for Tissue Engineering: Interactions with Normal Human Fibroblasts

    Article • Tissue Engineering, December 2003, Mary Ann Liebert Inc

    Dr. Ilaria Dal Prà

  63. Silk fibroin/poly(carbonate)-urethane as a substrate for cell growth: in vitro interactions with human cells

    Article • Biomaterials, February 2003, Elsevier

    Dr. Ilaria Dal Prà, Anna Chiarini

  64. Role of p75 Neurotrophin Receptor in the Neurotoxicity by β-amyloid Peptides and Synergistic Effect of Inflammatory Cytokines

    Article • The Journal of Experimental Medicine, April 2002, Rockefeller University Press

    Dr. Ilaria Dal Prà

  65. Protein Kinase C-βIIIs an Apoptotic Lamin Kinase in Polyomavirus-transformed, Etoposide-treated pyF111 Rat Fibroblasts

    Article • Journal of Biological Chemistry, March 2002, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr. Ilaria Dal Prà, Anna Chiarini

  66. Neurotrophin p75 Receptor Is Involved in Neuronal Damage by Prion Peptide-(106–126)

    Article • Journal of Biological Chemistry, August 2001, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr. Ilaria Dal Prà

  67. Increased Activity of the Protein Kinase C-δ Holoenzyme in the Cytoplasmic Particulate Fraction Precedes the Activation of Caspases in Polyomavirus-Transformed pyF111 Rat Fibroblasts Exposed to Calphostin C or Topoisomerase-II Inhibitors

    Article • Experimental Cell Research, March 2000, Elsevier

    Dr. Ilaria Dal Prà, Anna Chiarini

  68. β-Amyloid Activates the O⨪2Forming NADPH Oxidase in Microglia, Monocytes, and Neutrophils

    Article • Journal of Biological Chemistry, May 1999, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr. Ilaria Dal Prà

  69. Changes in Nuclear Protein Kinase C-δ Holoenzyme, Its Catalytic Fragments, and Its Activity in Polyomavirus-Transformed pyF111 Rat Fibroblasts while Proliferating and Following Exposure to Apoptogenic Topoisomerase-II Inhibitors

    Article • Experimental Cell Research, May 1999, Elsevier

    Dr. Ilaria Dal Prà, Anna Chiarini

  70. Opposite effects of cell differentiation and apoptosis on Ap3A/Ap4A ratio in human cell cultures

    Article • FEBS Letters, September 1997, Wiley

    Dr. Ilaria Dal Prà

  71. Silk fibroin-polyurethane scaffolds for tissue engineering

    Article • Institute of Electrical & Electronics Engineers (IEEE)

    Dr. Ilaria Dal Prà, Anna Chiarini