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  1. Effect of Pharmaceutical Intervention in Pharmacologically Treated Hypertensive Patients—A Cluster-Randomized Clinical Trial: AFPRES-CLM Study

    Article • Journal of Personalized Medicine, October 2023, MDPI AG

    Dr Cristina Núñez

  2. Morphine-withdrawal aversive memories and their extinction modulate H4K5 acetylation and Brd4 activation in the rat hippocampus and basolateral amygdala

    Article • Biomedicine & Pharmacotherapy, September 2023, Elsevier

    Dr Cristina Núñez

  3. Dopamine D3 Receptor Modulates Akt/mTOR and ERK1/2 Pathways Differently during the Reinstatement of Cocaine-Seeking Behavior Induced by Psychological versus Physiological Stress

    Article • International Journal of Molecular Sciences, July 2023, MDPI AG

    Dr Cristina Núñez

  4. Editorial: Unraveling vulnerability factors in addiction drug use and potential treatments

    Article • Frontiers in Neuroscience, July 2022, Frontiers

    Dr Cristina Núñez

  5. Molecular Mechanisms Underlying the Retrieval and Extinction of Morphine Withdrawal-Associated Memories in the Basolateral Amygdala and Dentate Gyrus

    Article • Biomedicines, March 2022, MDPI AG

    Dr Cristina Núñez

  6. Disentangling the molecular mechanisms underlying the retrieval and extinction of morphine withdrawal-associated memories in the basolateral amygdala and dentate gyrus

    Article • February 2022, Cold Spring Harbor Laboratory Press

    Dr Cristina Núñez

  7. Distinct Regulation of Dopamine D3 Receptor in the Basolateral Amygdala and Dentate Gyrus during the Reinstatement of Cocaine CPP Induced by Drug Priming and Social Stress

    Article • International Journal of Molecular Sciences, March 2021, MDPI AG

    Dr Cristina Núñez

  8. Distinct regulation of dopamine D3 receptor in the basolateral amygdala and dentate gyrus during the reinstatement of cocaine CPP induced by drug priming and social stress

    Article • January 2021, Cold Spring Harbor Laboratory Press

    Dr Cristina Núñez

  9. Blockade of D3 receptor prevents changes in DAT and D3R expression in the mesolimbic dopaminergic circuit produced by social stress- and cocaine prime-induced reinstatement of cocaine-CPP

    Article • Journal of Psychopharmacology, July 2020, SAGE Publications

    Dr Cristina Núñez

  10. Unraveling the molecular mechanisms involved in alcohol intake and withdrawal in adolescent mice exposed to alcohol during early life stages

    Article • Progress in Neuro-Psychopharmacology and Biological Psychiatry, June 2020, Elsevier

    Dr Cristina Núñez

  11. Pharmacological modulation of the behavioral effects of social defeat in memory and learning in male mice

    Article • Psychopharmacology, May 2019, Springer Science + Business Media

    Dr Cristina Núñez

  12. Modulation of stress- and cocaine prime-induced reinstatement of conditioned place preference after memory extinction through dopamine D3 receptor

    Article • Progress in Neuro-Psychopharmacology and Biological Psychiatry, January 2019, Elsevier

    Dr Cristina Núñez

  13. The involvement of CRF1 receptor within the basolateral amygdala and dentate gyrus in the naloxone-induced conditioned place aversion in morphine-dependent mice

    Article • Progress in Neuro-Psychopharmacology and Biological Psychiatry, June 2018, Elsevier

    Dr Cristina Núñez

  14. Repeated social defeat and the rewarding effects of cocaine in adult and adolescent mice: dopamine transcription factors, proBDNF signaling pathways, and the TrkB receptor in the mesolimbic system

    Article • Psychopharmacology, May 2017, Springer Science + Business Media

    Dr Cristina Núñez

  15. Different contribution of glucocorticoids in the basolateral amygdala to the formation and expression of opiate withdrawal-associated memories

    Article • Psychoneuroendocrinology, December 2016, Elsevier

    Dr Cristina Núñez

  16. Glucocorticoid Homeostasis in the Dentate Gyrus Is Essential for Opiate Withdrawal-Associated Memories

    Article • Molecular Neurobiology, October 2016, Springer Science + Business Media

    Dr Cristina Núñez

  17. Corticotropin-releasing factor 1 receptor mediates the activity of the reward system evoked by morphine-induced conditioned place preference

    Article • Neuropharmacology, August 2015, Elsevier

    Dr Cristina Núñez

  18. Regulation of dopaminergic markers expression in response to acute and chronic morphine and to morphine withdrawal

    Article • Addiction Biology, December 2014, Wiley

    Dr Cristina Núñez

  19. Glial activation and midkine and pleiotrophin transcription in the ventral tegmental area are modulated by morphine administration

    Article • Journal of Neuroimmunology, September 2014, Elsevier

    Dr Cristina Núñez

  20. Dysregulation of dopaminergic regulatory mechanisms in the mesolimbic pathway induced by morphine and morphine withdrawal

    Article • Referate und Beiträge zur Anatomie und Entwickelungsgeschichte, April 2014, Springer Science + Business Media

    Dr Cristina Núñez

  21. 10.1111/bph.12083

    Article • Addiction Biology, August 2013, Wiley

    Dr Cristina Núñez

  22. Differential Changes in Expression of Stress- and Metabolic-Related Neuropeptides in the Rat Hypothalamus during Morphine Dependence and Withdrawal

    Article • PLoS ONE, June 2013, PLOS

    Dr Cristina Núñez

  23. Morphine administration modulates expression of Argonaute 2 and dopamine-related transcription factors involved in midbrain dopaminergic neurons function

    Article • British Journal of Pharmacology, March 2013, Wiley

    Dr Cristina Núñez

  24. Glucocorticoids Regulation of FosB/ΔFosB Expression Induced by Chronic Opiate Exposure in the Brain Stress System

    Article • PLoS ONE, November 2012, PLOS

    Dr Cristina Núñez

  25. Hypothalamic Orexin-A Neurons Are Involved in the Response of the Brain Stress System to Morphine Withdrawal

    Article • PLoS ONE, May 2012, PLOS

    Dr Cristina Núñez

  26. Involvement of Noradrenergic Transmission in the PVN on CREB Activation, TORC1 Levels, and Pituitary-Adrenal Axis Activity during Morphine Withdrawal

    Article • PLoS ONE, February 2012, PLOS

    Dr Cristina Núñez

  27. 10.1016/j.neuint.2010.06.011

    Article • British Journal of Pharmacology, January 2011, Wiley

    Dr Cristina Núñez

  28. CP154,526, a selective inhibitor of CRF 1 receptor, blocks the acquisition of opioid withdrawal-induced conditioned place aversion in mice

    Article • Pharmacological Reports, January 2011, Springer Science + Business Media

    Dr Cristina Núñez

  29. Morphine withdrawal induces the activation of the orexinergic neurons in the rat lateral hypothalamus

    Article • Pharmacological Reports, January 2011, Springer Science + Business Media

    Dr Cristina Núñez

  30. δFosB expression in the brain stress system from adrenalectomized rats during morphine dependence

    Article • Pharmacological Reports, January 2011, Springer Science + Business Media

    Dr Cristina Núñez

  31. Changes in metabolic-related variables during chronic morphine treatment

    Article • Neurochemistry International, October 2010, Elsevier

    Dr Cristina Núñez

  32. Induction of FosB/ΔFosB in the brain stress system-related structures during morphine dependence and withdrawal

    Article • Journal of Neurochemistry, April 2010, Wiley

    Dr Cristina Núñez

  33. Effects of Corticotropin-Releasing Factor Receptor-1 Antagonists on the Brain Stress System Responses to Morphine Withdrawal

    Article • Molecular Pharmacology, February 2010, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr Cristina Núñez

  34. Effects of rolipram and diazepam on the adaptive changes induced by morphine withdrawal in the hypothalamic paraventricular nucleus

    Article • European Journal of Pharmacology, October 2009, Elsevier

    Dr Cristina Núñez

  35. Elevated Glucocorticoid Levels Are Responsible for Induction of Tyrosine Hydroxylase mRNA Expression, Phosphorylation, and Enzyme Activity in the Nucleus of the Solitary Tract during Morphine Withdrawal

    Article • Endocrinology, July 2009, Endocrine Society

    Dr Cristina Núñez

  36. Regulation of extracellular signal-regulated kinases (ERKs) by naloxone-induced morphine withdrawal in the brain stress system

    Article • Naunyn-Schmiedeberg s Archives of Pharmacology, June 2008, Springer Science + Business Media

    Dr Cristina Núñez

  37. Regulation of Serine (Ser)-31 and Ser40 Tyrosine Hydroxylase Phosphorylation during Morphine Withdrawal in the Hypothalamic Paraventricular Nucleus and Nucleus Tractus Solitarius-A2Cell Group: Role of ERK1/2

    Article • Endocrinology, December 2007, Endocrine Society

    Dr Cristina Núñez

  38. Activation of stress‐related hypothalamic neuropeptide gene expression during morphine withdrawal

    Article • Journal of Neurochemistry, January 2007, Wiley

    Dr Cristina Núñez

  39. Morphine withdrawal-induced c-fos expression in the hypothalamic paraventricular nucleus is dependent on the activation of catecholaminergic neurones

    Article • Journal of Neurochemistry, September 2002, Wiley

    Dr Cristina Núñez