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GLP-1 receptor agonists are associated with a slight increase in risk of ischemic optic neuropathy (~1 extra case per 2,700 patients), yet their cardio-metabolic benefits far outweigh this rare harm.

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This page is a summary of: Association Between GLP-1 Receptor Agonists and Ischemic Optic Neuropathy: A Meta-analysis, Diabetes Care, January 2026, American Diabetes Association,
DOI: 10.2337/dc25-1238.
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