Early Detection of β-Cell Decline Using Home Dried-Blood-Spot C-Peptide Levels in New-Onset Type 1 Diabetes

What is it about?

We investigated whether at-home dried blood spot (DBS) C-peptide testing could be a simpler alternative to the standard mixed-meal tolerance test for tracking beta-cell decline in newly diagnosed type 1 diabetes. Our findings show that six-month changes in stimulated DBS C-peptide predicted beta-cell function at 12 months, highlighting its potential for monitoring disease progression.

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