Molecular allergology: a clinical laboratory tool for precision diagnosis, stratification and follow-up of allergic patients

What is it about?

Allergic diseases affect nowadays up to 30% of the population. Since the turn of the 21st century, the place of the clinical laboratory in the diagnosis and management of allergic diseases has dramatically shifted to the frontstage, thanks to a novel precision medicine tool known as molecular allergens. Allergens are defined by their ability to trigger allergic reactions. Humans encounter potential allergens from various sources: pollen grains, house dust mites, food, insect stings etc. Access to the molecular level of allergens is recent, progressively implemented since the end of the 20th century as protein tools for the clinical laboratory. Our review aims to educate clinical laboratory specialists on molecular allergens and their use for the diagnosis and management of allergic diseases.

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