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Knowledge of factors that lead to and sustain excessive drinking are crucial in developing effective prevention and intervention programs. The authors provided the first repeated assessment of acute alcohol responses in the same people over a substantial period of time. They found that persons developing alcohol use disorder had higher initial pleasurable responses to alcohol and these stimulating and rewarding responses were magnified over time. This suggests that long-held views of tolerance to alcohol's pleasurable effects in those becoming addicted were not substantiated.

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This page is a summary of: Subjective Responses to Alcohol in the Development and Maintenance of Alcohol Use Disorder, American Journal of Psychiatry, June 2021, American Psychiatric Association,
DOI: 10.1176/appi.ajp.2020.20030247.
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